• Title/Summary/Keyword: Detection of Probability

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Absorbed Spectrum Comparison of Lead and Tungsten in Continuous X-ray Energy using Monte Carlo Simulation (몬테카를로 시뮬레이션을 통한 연속 엑스선 에너지에서 납(Pb)과 텅스텐(W)의 흡수 스펙트럼 비교 연구)

  • Kim, Kyotae;Kang, Sangsik;Noh, Sicheul;Jung, Bongjae;Cho, Changhoon;Heo, Yeji;Park, Jikoon
    • Journal of the Korean Society of Radiology
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    • v.6 no.6
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    • pp.483-487
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    • 2012
  • In 1895, the discovered X-ray is used for not only in this field of medicine wide but also field. The detection of radiation after, people realized the risk of the radiation exposured recommended the principle about the protection of radiation by the part of the effort for lowering the radiation exposure. In this recommendation, all unnecessary radiation exposure have to be prevented by All doses include the protection of radiation, general idea of applicable two kinds of that it has to low maintain. Presently, in the General X-ray room of the clinical, the lead (Pb) was used for the shielding, However, because it had the problem of the lead poisoning which is fatal in the human body, the alternatives was showed. and Among them, the material that it is the tungsten was presented. in this research, the absorbed spectrum according to the thickness in the continuous X-ray energy of the tungsten which is not harmful to the human body through the Monte Carlo simulation, tried to compare with the absorbed spectrum of the lead (Pb). The tungsten confirmed that simulation presumption than result lead in the whole domain that absorbed probability was higher and it is considered that tungsten shows the absorbed efficiency higher than the lead in particularly, 70 keV ~ 90 keV and the tungsten is more useful to the X-ray energy cover of the high energy diagnostic area.

Evaluation of Serological Surveillance System for Improving Foot-and-Mouth Disease Control (구제역 관리를 위한 혈청학적 예찰계획 평가)

  • Pak, Son-Il;Shin, Yeun-Kyung
    • Journal of Veterinary Clinics
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    • v.30 no.4
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    • pp.258-263
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    • 2013
  • The primary goal of this study was to compute sample sizes required to achieve the each aim of a variety of foot-and-mouth disease (FMD) surveillance programs, using a statistically valid technique that takes the following factors into account: sensitivity (Se) and specificity (Sp) of diagnostic test system, desired minimum detectable prevalence, precision, population size, and desired power of the survey. In addition, sample sizes to detect FMD if the disease is present and also as proof of freedom were computed. The current FMD active surveillance programs consist of clinical, virological, and serological surveillance. For the 2012 serological surveillance, annual sample sizes (n = 265,065) are planned at four separate levels: statistical (n = 60,884) and targeted (n = 115,232) at breeding pig farms and slaughter house, in together with the detection of structural proteins (SP) antibodies against FMD (n = 88,949). Overall, the sample size was not designed taking the specific aims of each surveillance stream into account. The sample sizes for statistical surveillance, assuming stratified two-stage sampling technique, was based to detect at least one FMD-infected case in the general population. The resulting sample size can be used to obtain evidence of freedom from FMD infection, not for detecting animals that have antibodies against FMD virus non-structural proteins (NSP). Additionally, sample sizes for targeted surveillance were not aimed for the population at risk, and also without consideration of statistical point of view. To at least the author's knowledge, sampling plan for targeted, breeding pig farms and slaughter house is not necessary and need to be included in the part of statistical surveillance. Assuming design prevalence of 10% in an infinite population, a total of 29 animals are required to detect at least one positive with probability of 95%, using perfect diagnostic test system (Se = Sp = 100%). A total of 57,211 animals needed to be sampled to give 95% confidence of estimating SP prevalence of 80% at the individual animal-level with a precision of ${\pm}5%$, assuming 800 herds with an average 200 heads per farm, within-farm variance of 0.2, between-farm variance of 0.05, cost ratio of 100:1 of farm against animals. Furthermore, 779,736 animals were required to demonstrate FMD freedom, and the sample size can further be reduced depending on the parameters assumed.

Knowledge, Barriers and Attitudes Towards Breast Cancer Mammography Screening in Jordan

  • Abu-Helalah, Munir Ahmad;Alshraideh, Hussam Ahmad;Al-Serhan, Ala-Aldeen Ahmad;Kawaleet, Mariana;Nesheiwat, Adel Issa
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.9
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    • pp.3981-3990
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    • 2015
  • Background: Breast cancer is the most common type of cancer in Jordan. Current efforts are focused on annual campaigns aimed at increasing awareness about breast cancer and encouraging women to conduct mammogram screening. In the absence of regular systematic screening for breast cancer in Jordan, there is a need to evaluate current mammography screening uptake and its predictors, assess women's knowledge and attitudes towards breast cancer and screening mammograms and to identify barriers to this preventive service. Materials and Methods: This cross-sectional study was conducted in six governorates in Jordan through face-to-face interviews on a random sample of women aged 40 to 69 years. Results: A total of 507 participants with mean age of $46.8{\pm}7.8$ years were interviewed. There was low participation rate in early detection of breast cancer practices. Breast self-examination, doctor examination and periodic mammography screening were reported by 34.9%, 16.8% and 8.6% of study participants, respectively. Additionally 3.8% underwent breast cancer screening at least once but not periodically, while 87.6% had never undergone mammography screening. Reported reasons for conducting the screening were: perceived benefit (50%); family history of breast cancer (23.1%); perceived severity (21.2%); and advice from friend or family member (5.8%). City residents have shown higher probability of undergoing mammogram than those who live in towns or villages. Results revealed negative perceptions and limited knowledge of study participants on breast cancer and breast cancer screening. The most commonly reported barriers for women who never underwent screening were: fear of results (63.8%); no support from surrounding environment (59.7); cost of the test (53.4%); and religious belief, i.e. Qadaa Wa Qadar (51.1%). Conclusions: In the absence of regular systematic screening for breast cancer in Jordan, the uptake of this preventive service is very low. It is essential for the country of Jordan to work on applying regular systematic mammography screening for breast cancer. Additionally, there is a need for improvement in the current health promotion programmes targeting breast cancer screening. Other areas that could be targeted in future initiatives in this field include access to screening in rural areas and removal of current barriers.

PHA-Induced Peripheral Blood Cytogenetics and Molecular Anslysis : a Valid Diagnostic and Follow-up Modality For Acute Primyelocytic Leukemia Patients Treated With ATRA and/or Arsenic Tri-oxide

  • Baba, Shahid M;Azad, Niyaz A;Shah, Zaffar A;Afroze, Dil;Pandith, Arshad A;Jan, Aleem;Aziz, Sheikh A;Dar, Fayaz A
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.4
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    • pp.1999-2006
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    • 2016
  • Background: Acute promyelocytic leukemia (APML) is characterized by the reciprocal translocation t(15;17) (p22;p12) resulting in the PML-$RAR{\alpha}$ fusion gene. A dual diagnostic and follow up approach was applied including cytogenetic demonstration of the t(15;17) translocation and detection dg PML-$RAR{\alpha}$ chimeric transcripts by molecular means. Purpose: Conventional cytogenetics involving bone marrow is beset with high probability of poor metaphase index and was substituted with phytohemagglutinin (PHA)-induced peripheral blood culture based cytogenetic analysis as a diagnostic & follow up modality in APML patients of Kashmir (North India). Both qualitative (RT-PCR) and quantitative (Q-PCR) tests were simultaneously carried out to authenticte the modified cytogenetics. Materials and Method: Patient samples were subjected to the said techniques to establish their baseline as well as follow-up status. Results: Initial cytogenetics revealed 30 patients (81%) Positive for t(15;17) whereas 7 (19%) had either cryptic translocation or were negative for t(15;17). Two cases had chromosome 16q deletion and no hallmark translocation t(15;17). Q-PCR status for PML-$RAR{\alpha}$ was found to be positive for all patients. All the APML patients were reassessed at the end of consolidation phase and during maintenance phase of chemotherapy where 6 patients had molecular relapse, wherein 4 also demonstrated cytogenetic relapse. Conclusions: It was found that PHA-induced peripheral blood cytogenetics along with molecular analysis could prove a reliable modality in the diagnosis and assessment of follow up response of APML patients.

Development of Intelligent Database Program for PSI/ISI Data Management of Nuclear Power Plant (원자력발전소 PSI/ISI 데이터 관리를 위한 지능형 데이터 베이스 프로그램 개발)

  • Park, Un-Su;Park, Ik-Keun;Um, Byong-Guk;Park, Yun-Won;Kang, Suk-Chul
    • Journal of the Korean Society for Nondestructive Testing
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    • v.18 no.5
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    • pp.389-397
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    • 1998
  • For an effective and efficient management of large amounts of preservice/inservice inspection(PSI/ISI) data in nuclear power plants, an intellegent Windows 95-based data management program was developed. This program enables the prompt extraction of previously conducted PSI/ISI conditions and results so that the time-consuming data management, painstaking data processing and analysis in the past are avoided. The program extracts, and the associated remedies. Furthermore, additional inspection data and comments can be easily added or deleted for subsequent PSI/ISI operation. Although the initial version of the program was applied to Kori nuclear power plant, this program can be equally applied to other nuclear power plant. And also this program can be used to offer the fundamental data for application of evaluation data related to fracture mechanics analysis(FMA), probabilistic reliability assessment(PRA) of PSI/ISI results, performance demonstration initiative(PDI) and risk-informed ISI based on probability of detection(POD) information of ultrasonic examination. Besides, the program can be further developed as a unique PSI/ISI data management expert system that can be apart of PSI/ISI data management expert system that can be a part of PSI/ISI Total Support System(TSS) for Korean nuclear power plants.

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Monitoring Extensive Breeding Populations and Daily Call Activity of the Gold-spotted Pond Frog, Rana chosenica in Chungju City and Chungwon Gun (청주시와 청원군에서 금개구리 (Rana chosenica) 번식 군집 모니터링 및 일중 울음소리 빈도)

  • Sung, Ha-Cheol;Cha, Sang-Min;Kim, Suk-Kyung;Park, Dae-Sik;Park, Shi-Ryong;Cheong, Seok-Wan
    • Korean Journal of Environmental Biology
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    • v.25 no.2
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    • pp.94-99
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    • 2007
  • To investigate the spatial distribution and daily calling pattern of the Gold-spotted pond frog, Rana chosenica, in Chungju city and Chungwon gun, Chungbuk province, Korea, we divided the study area into 226 plots with a $2{\times}2km^2$ plot on the map, of which we assigned 32 plots for monitoring populations. Call monitoring on whether the species are present or not were conducted for 5 minutes in between sunset and the midnight from at the end of May to July in 2006. Gold-spotted pond frogs were detected at least once four out of 32 plots. Using program Presence, we obtained site occupancy rate as 0.170 which was quite low compared with other species, while detection probability was 0.66 that propose at least three times to visit the monitoring site to confirm the absence of the frogs. The frogs were actively calling from 21:00 to 02:00, and the number of calling male was significantly and highly correlated with water temperature and humidity. This study shows the present status of the Gold-spotted pond frogs in Chungju city and Chungwon gun and we suggests various effective monitoring methods based on the this study.

Risk Assessment for Aquatic Organisms of Pesticides Detected In Water Phase of Six Major Rivers in Korea (주요 하천수역에서 검출된 농약의 수서생물에 대한 위해성 평가)

  • Lee, Ji-Ho;Park, Byung-Jun;Kim, Jin-Kyung;Kim, Won-Il;Hong, Su-Myung;Im, Geon-Jae;Hong, Moo-Ki
    • The Korean Journal of Pesticide Science
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    • v.15 no.1
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    • pp.48-54
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    • 2011
  • Risk assessments of pesticides detected in six major rivers during peak season were estimated for algae, Daphnia, and fish using hazard quotient (HQ) indexes. The eight pesticides (isoprothiolane, hexaconazole, diazinon, chlorpyrifos, prothiofos, alachlor, butachlor, molinate) were detected within the range of 0.027~12.871 ${\mu}g/L$. Detection frequency of isoprothiolate was estimated to be high at 67.5%, and those of the others varied from 15.0 to 37.5%, Hazard Quotients (HQ) indexes varied by freshwater organisms (algae, Daphnia, and fish). Overall, the ecological risk probability due to exposure of pesticides detected in major rivers did not reveal based on HQ indexes below 1.0. Particularly, butachlor and molinate for algae, chlorpyrifos, diazinon, prothiofos for Daphnia, and chlorpyrifos for fish acted as dominant contributors in increasing the ecological risk in six major rivers. This implied that integrated ecological risk assessment is required using various biological species, reflecting toxicity sensitivity. This study may provide the essential data in establishing the priority for pesticides management in major rivers, Korea.

The Study on Design of Semiconductor Detector for Checking the Position of a Radioactive Source in an NDT (비파괴검사 분야에서 방사선원의 위치 확인을 위한 반도체 검출기 설계에 관한 연구)

  • Kim, Kyo-Tae;Kim, Joo-Hee;Han, Moo-Jae;Heo, Ye-Ji;Ahn, Ki-Jung;Park, Sung-Kwang
    • Journal of the Korean Society of Radiology
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    • v.11 no.3
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    • pp.171-175
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    • 2017
  • In the non-destructive inspection field, we invest a lot of time and resources in developing the radiation source system to ensure the safety of the workers. However, the probability of accidents is still high. In order to prevent potential radiation accidents in advance, it is necessary to directly verify the position of the radiation source, but the research is still insufficient. In this study, we developed a monitoring system that can detect the position of the radiation source in the source guide tube in the gamma-ray irradiator. The characteristics of the radiation detector are estimated by monte carlo simulation. As a result, the radiation detector for Ir-192 gamma-ray energy was analyzed to have secondary electron equilibrium at $150{\mu}m$ regardless of the semiconductor material. Also, it is expected that the gamma ray response characteristic is the best in $HgI_2$. These results are expected to be used as a basis for determining the optimal thickness of the radiation detector located in the detection part of the future monitoring system. In addition, when developing a monitoring system based on this, radiation workers can easily recognize the danger and secure safety, as well as prevent and preemptively respond to potential radiation accidents.

Improved Direction of Arrival Estimation Based on Coprime Array and Propagator Method by Noise Power Spectral Density Estimation (잡음 파워 스펙트럼 밀도 추정을 이용한 서로소 배열과 프로퍼게이터 기법 기반의 향상된 도래각 추정 기법)

  • Byun, Bu-Guen;Yoo, Do-Sik
    • Journal of Advanced Navigation Technology
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    • v.20 no.4
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    • pp.367-373
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    • 2016
  • We propose an improved direction of arrival (DoA) estimation algorithm based on co-prime array and propagator method. The propagator method with co-prime array does not require singular value decomposition (SVD) requiring much less computational complexity but exhibiting somewhat worse performance in comparison with MUSIC based on co-prime array. We notice that one cause of the performance degradation was in the avoidance of the usage of the diagonal elements of the signal autocorrelation matrix that contains the noise power spectral density. So we propose an algorithm with the diagonal elements of the signal autocorrelation matrix based on the fact that the noise power spectral density can be estimated using noise observation over a long period of time. We observe, through simulations, that the proposed scheme in this paper improves the performance, with 4 times more computational requirement, by signal-to-noise ratio of 1.5dB and by DoA resolution of $0.7^{\circ}$ at the detection probability of 95% compared with the previously introduced co-prime array propagator scheme, resulting in performance much closer to that of co-prime array-based MUSIC scheme.

Prevalence-based Interpretation of Predictive Values of Diagnostic Tests: An Example for Detection of Canine Heartworm Infection (진단키트 검사결과에 대한 유병율 위주 해석: 개 심장사상충의 예)

  • Park, Choi-Kyu;Pak, Son-Il
    • Journal of Veterinary Clinics
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    • v.26 no.2
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    • pp.130-133
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    • 2009
  • The use of screening tests as part of a diagnostic work-up is common in domestic canine practice, but understanding of the diagnostic test characteristics and factors affecting diagnostic accuracy is not clear among clinicians. This article was aimed to provide clinicians with a better understanding on the selection of test kits and with a proper interpretation of test results using an example from heartworm(Dirofilaria immitis) studies. From the literatures, diagnostic accuracy varied depending on the kits: percent average sensitivity and specificity of ELISA antigen-detecting kits were DiroChek(Synbiotics, USA) 78.1 and 95.2, SNAP(IDEXX, USA) 66.3 and 98.1, and Solo Step(Heska, Switzerland) 69.5 and 97.5, respectively, while the values for three hematological methods(Modified Knott's, direct smear and capillary tube) ranged from 38.4 to 81.8% and from 96.9 to 100%, respectively. Furthermore, it was also reported that the prevalence of heartworm disease in domestic dog populations varied depending on the regions studied: 2.5-22.8% for microfilarial test and 2.2-66.3% by ELISA. The values of predictive values for positive(PPV) and negative(NPV) provide useful information to clinicians on the probability of heartworm infection, but the PPV and NPV are greatly dependent on the heartworm prevalence. This suggests that PPV or NPV values of a test should be interpreted carefully in different clinical settings. Practical methods on the interpretation taking into account heartworm prevalence were discussed.