• Title/Summary/Keyword: Design spectrum

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A Study on the Breakwater Characteristics considering Seismic Magnitude (지진규모를 고려한 방파제 특성에 관한 연구)

  • Jeong, Jin-Ho;Lee, Kwang-Yeol;Lim, Chang-Kyu
    • Journal of the Korean Geosynthetics Society
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    • v.13 no.1
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    • pp.71-83
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    • 2014
  • Busan is located at the mouth of Nakdong River and if an earthquake occurs, it is very likely that the damage by the earthquake will be worse as liquefaction can happen in the sand layer, builtup soil, and landfill ground due to amplification in the lower sedimentary layer that is well developed in the river mouth. Therefore, this study first examined the possibility of liquefaction in the replaced sand layer under breakwater using 14 earthquakes in 5.6-7.9 scale and artificial earthquakes including the seismic wave suggested in the standard specifications for seismic design of ports and fishing port facilities to evaluate the stability of breakwater which is the primary protective structure for port facilities against earthquakes. Second, analysis on characteristics of the seismic energy and acceleration response spectrum by size of earthquake was performed to suggest the most appropriate size of seismic wave for the condition in Korea. Third, finite element analysis was performed using the suggested seismic wave to study the characteristics of earthquake by finding the dynamic lateral displacement of breakwater and verifying the stability of structure and the displacement and forces occurring at geotextile. Results of the study showed that the possibility of liquefaction in the landfill and replaced sand layer, the dynamic lateral displacement of breakwater, and changes of geotextile are greatly affected by the subsurface ground (replaced sand layer).

Screening and isolation of antibacterial proteinaceous compounds from flower tissues: Alternatives for treatment of healthcare-associated infections

  • de Almeida, Renato Goulart;Silva, Osmar Nascimento;de Souza Candido, Elizabete;Moreira, Joao Suender;Jojoa, Dianny Elizabeth Jimenez;Gomes, Diego Garces;de Souza Freire, Mirna;de Miranda Burgel, Pedro Henrique;de Oliveira, Nelson Gomes Junior;Valencia, Jorge William Arboleda;Franco, Octavio Luiz;Dias, Simoni Campos
    • CELLMED
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    • v.4 no.1
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    • pp.5.1-5.8
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    • 2014
  • Healthcare-associated infection represents a frequent cause of mortality that increases hospital costs. Due to increasing microbial resistance to antibiotics, it is necessary to search for alternative therapies. Consequently, novel alternatives for the control of resistant microorganisms have been studied. Among them, plant antimicrobial protein presents enormous potential, with flowers being a new source of antimicrobial molecules. In this work, the antimicrobial activity of protein-rich fractions from flower tissues from 18 different species was evaluated against several human pathogenic bacteria. The results showed that protein-rich fractions of 12 species were able to control bacterial development. Due its broad inhibition spectrum and high antibacterial activity, the protein-rich fraction of Hibiscus rosa-sinensis was subjected to DEAE-Sepharose chromatography, yielding a retained fraction and a non-retained fraction. The retained fraction inhibits 29.5% of Klebsiella pneumoniae growth, and the non-retained fraction showed 31.5% of growth inhibition against the same bacteria. The protein profile of the chromatography fractions was analyzed by using SDS-PAGE, revealing the presence of two major protein bands in the retained fraction, of 20 and 15 kDa. The results indicate that medicinal plants have the biotechnological potential to increase knowledge about antimicrobial protein structure and action mechanisms, assisting in the rational design of antimicrobial compounds for the development of new antibiotic drugs.

Effect of Grinding on Solubility and Particle Size of Pefioxacin by Planetary Ball-Mill (유성볼밀을 이용한 난용성 Pefloxacin의 분쇄조작에 의한 입자 설계)

  • 임영근;김진우;최우식;야마모토;정해영
    • Journal of Life Science
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    • v.9 no.2
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    • pp.194-200
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    • 1999
  • Grinding aid is a necessary unit operation when the raw materials are handled in solid form, and the purpose is to improve the bioavailability by reducing the particle size. For the particle design of pefloxacin, the dry planetary ball-mill was used. With the drying process, 330 g of zirconia ball with its size of 2 mm in diameter and 10 g of pefloxacin were transferred to the pot and mixed well. The mixture was ground at 112 rpm (60 Hz) for 15, 30, and 60 min, respectively. The most satisfactory grinding products were generated at 15 min of grinding time for their particle size. The volume mean diameter $\X_50$ of the grinding products was 2.97 $\mu$m. X-ray diffraction (XRD), differential scanning calorimeter (DSC), and infrared spectroscopy (IR) patterns were relatively unchanged before pulverizing pefloxacin and in the progress of grinding. Thus, these results suggest that this pulverizing method can be used for grinding products without evident effect on stability of the drug pefloxacin. Dissolution test was carried out to set up the optimal detective condition against residual antibacteria of fish by HPLC. The grinding pefloxacin for 15 min is most effective in dissolution test.

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Sensitivity Analysis of Satellite BUV Ozone Profile Retrievals on Meteorological Parameter Errors (기상 입력장 오차에 대한 자외선 오존 프로파일 산출 알고리즘 민감도 분석)

  • Shin, Daegeun;Bak, Juseon;Kim, Jae Hwan
    • Korean Journal of Remote Sensing
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    • v.34 no.3
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    • pp.481-494
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    • 2018
  • The accurate radiative transfer model simulation is essential for an accurate ozone profile retrieval using optimal estimation from backscattered ultraviolet (BUV) measurement. The input parameters of the radiative transfer model are the main factors that determine the model accuracy. In particular, meteorological parameters such as temperature and surface pressure have a direct effect on simulating radiation spectrum as a component for calculating ozone absorption cross section and Rayleigh scattering. Hence, a sensitivity of UV ozone profile retrievals to these parameters has been investigated using radiative transfer model. The surface pressure shows an average error within 100 hPa in the daily / monthly climatological data based on the numerical weather prediction model, and the calculated ozone retrieval error is less than 0.2 DU for each layer. On the other hand, the temperature shows an error of 1-7K depending on the observation station and altitude for the same daily / monthly climatological data, and the calculated ozone retrieval error is about 4 DU for each layer. These results can help to understand the obtained vertical ozone information from satellite. In addition, they are expected to be used effectively in selecting the meteorological input data and establishing the system design direction in the process of applying the algorithm to satellite operation.

Fabrication of [320×256]-FPA Infrared Thermographic Module Based on [InAs/GaSb] Strained-Layer Superlattice ([InAs/GaSb] 응력 초격자에 기초한 [320×256]-FPA 적외선 열영상 모듈 제작)

  • Lee, S.J.;Noh, S.K.;Bae, S.H.;Jung, H.
    • Journal of the Korean Vacuum Society
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    • v.20 no.1
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    • pp.22-29
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    • 2011
  • An infrared thermographic imaging module of [$320{\times}256$] focal-plane array (FPA) based on [InAs/GaSb] strained-layer superlattice (SLS) was fabricated, and its images were demonstrated. The p-i-n device consisted of an active layer (i) of 300-period [13/7]-ML [InAs/GaSb]-SLS and a pair of p/n-electrodes of (60/115)-period [InAs:(Be/Si)/GaSb]-SLS. FTIR photoresponse spectra taken from a test device revealed that the peak wavelength (${\lambda}_p$) and the cutoff wavelength (${\lambda}_{co}$) were approximately $3.1/2.7{\mu}m$ and $3.8{\mu}m$, respectively, and it was confirmed that the device was operated up to a temperature of 180 K. The $30/24-{\mu}m$ design rule was applied to single pixel pitch/mesa, and a standard photolithography was introduced for [$320{\times}256$]-FPA fabrication. An FPA-ROIC thermographic module was accomplished by using a $18/10-{\mu}m$ In-bump/UBM process and a flip-chip bonding technique, and the thermographic image was demonstrated by utilizing a mid-infrared camera and an image processor.

Assessment of Surface Topographic Effect in Earthquake Ground Motion on the Upper Slope via Two-Dimensional Geotechnical Finite Element Modeling (이차원 지반 유한요소 모델링을 통한 사면상부 지진지반운동의 지표면 지형효과 분석)

  • Sun, Chang-Guk;Bang, Kiho;Cho, Wanjei
    • The Journal of Engineering Geology
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    • v.25 no.2
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    • pp.201-213
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    • 2015
  • Site effects resulting in the amplification of earthquake ground motion are strongly influenced not only by the subsurface soil conditions and structure, but also by the surface topography. Yet, over the last several decades, most studies of site-specific seismic responses in Korea have focused primarily on the seismic amplification associated with geologic and soil conditions. For example, the effects of local geology are now well established and have been incorporated into current Korean seismic design codes, whereas topographic effects have not been considered. To help address this shortcoming, two-dimensional (2D) seismic site response analyses, using finite element (FE) ground modeling with three different slope angles, were performed in order to assess the site effects of surface topography. We then compared our results, specifically peak ground acceleration (PGA) and acceleration response spectrum, to those of one-dimensional (1D) FE model analyses conducted alongside our study. Throughout much of the upper slope region, PGAs and spectral accelerations are larger in the 2D analyses than in the 1D analyses as a result of the topographic effect.

Growth-inhibitory Effects of Citrus Oils and Synthetic Agricultural Fungicides on Molds Isolated from Putrefied Citrus Fruits (감귤 부패 사상균에 대한 감귤 정유와 시판 합성 농약의 항균 효과)

  • Kim, Yu-Kyoung;Koh, Jeong-Sam;Huh, Yoon-Hee;Ko, Young-Hwan
    • Applied Biological Chemistry
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    • v.42 no.4
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    • pp.356-360
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    • 1999
  • Growth-inhibitory effects of citrus oils and agricultural fungicides, which were on the market, on several molds isolated from putrefied citrus fruits were investigated. When fungicidal activities of 11 kinds of synthetic agrochemicals against 6 species of molds, Alternaria alternata, Rhizopus sp., Botrytis cinerea, Monilia candida, Penicillium italicum and Penicillium digitatum, were investigated, agrochemicals containing mancozeb or fluazinam as an effective component had the broadest fungicidal spectrum. Agrochemicals containing iprodione, benomyl, azoxystrobin or thiophanate were less effective on the molds and those containing conazole derivative were intermediately effective. Resistance of the molds to the agrochemicals were species- and agrochemical-dependent. Among those molds tested, Penicillium italicum and Alternaria alternata showed relatively higher level of survival in the presence of synthetic fungicides. On the other hand, when the molds were exposed to citrus oils by direct contact, no cell could survive regardless of the species. The fungicidal activity of citrus oils was also confirmed by paper disk method and microscopic observation. These results suggested that citrus oils had broad killing activity against molds. Therefore, it would be necessary to design method for the application of citrus oils in order to improve post-harvest storage of citrus fruits.

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Processing and Physicochemical Properties of Collagen from Yellowfin Tuna (Thunnus albacares) Abdominal Skin (황다랑어 복부 껍질을 이용한 콜라겐의 제조 및 물리화학적 특성 해석)

  • Yoo, Sung-Jae;Cho, Sueng-Mock;Woo, Jin-Wook;Kim, Sang-Ho;Han, Yoo-Na;Ahn, Ju-Ryun;Kim, Su-Yeon;Kim, Tae-Wan;Kim, Seon-Bong
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.41 no.6
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    • pp.427-434
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    • 2008
  • Processing of collagen from yellowfin tuna (Thunnus albacares) abdominal skins was optimized by response surface methodology and central composite design. The values of independent variables at optimal conditions were NaOH concentration: 0.5 N, NaOH treatment time: 36.2 hr, pepsin concentration: 1:4.9 ratio (0.245%, w/v), and digestion time: 48.1 hr, respectively. The collagen content estimated under optimal conditions was 33.1%, and the actual experimental collagen content was 32.3%. Physicochemical properties of collagen from yellowfin tuna abdominal skin were investigated by amino acids analysis, SDS-PAGE, FT-IR, viscosity and denaturation temperature. Amino acids content of the collagen was 21.0%. SDS-PAGE pattern of the collagen showed two different $\alpha$-chain (${\alpha}_1$- and ${\alpha}_2$- chain), $\beta$-component and $\gamma$-component. The spectrum of FT-IR of the collagen showed wavenumber at 3,434, 1,650, 1,542 and $1,235\;cm^{-1}$ representing the regions of amide A, I, II and III, respectively. Relative viscosity of the collagen decreased continuously on heating up to $32^{\circ}C$, and the rate of decrease was retarded in the temperature range of $35-50^{\circ}C$. Denaturation temperature (Td) of the collagen solution (0.06%, w/v) was $31^{\circ}C$ and was lower than calf skin collagen ($35^{\circ}C$).

A Strategy for Developing New Road Projects (경관도로 등 신개념의 도로사업 개발에 관한 연구)

  • Kim, Eung-Cheol
    • International Journal of Highway Engineering
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    • v.9 no.2 s.32
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    • pp.115-127
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    • 2007
  • Developed countries, especially in road construction and management fields, introduce new road porjects such as National Scenic Byways Program(NSBP program) in USA and the Eco-road project in Japan. This study develops a conceptual model for deploying new road projects in Korea. The four step approach is suggested to create new road projects, including foundation of an act based on the existing Road Act, creation of new road project ideas, development of evaluation process and guidelines, and enhancement of an administrative scheme. To create new road projects, three different ways are devised; (1) designation of national roads having uniqueness in overall spectrum, (2) designation of roads having intrinsic values in a different aspect, (3) designation of single structures of engineering outcomes such as bridges, tunnels, new design techniques, considerable Value Engineering output, and well analyzed Life Cycle Cost Analysis practices. For the evaluation process, NSBP program of USA and/or Sustainable City Award program of Korea would be recommended. An administrative scheme and integrated funding process for the new road projects are also suggested based on evaluation of tasks of each team or division of Korea Ministry of Construction and Transportation.

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Frontiers in Magneto-optics of Magnetophotonic Crystals

  • Inoue, M.;Fedyanin, A.A.;Baryshev, A.V.;Khanikaev, A.B.;Uchida, H.;Granovsky, A.B.
    • Journal of Magnetics
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    • v.11 no.4
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    • pp.195-207
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    • 2006
  • The recently published and new results on design and fabrication of magnetophotonic crystals of different dimensionality are surveyed. Coupling of polarized light to 3D photonic crystals based on synthetic opals was studied in the case of low dielectric contrast. Transmissivity of opals was demonstrated to strongly depend on the propagation direction of light and its polarization. It was shown that in a vicinity of the frequency of a single Bragg resonance in a 3D photonic crystal the incident linearly polarized light excites inside the crystal the TE- and TM-eigen modes which passing through the crystal is influenced by Brags diffraction of electromagnetic field from different (hkl) sets of crystallographic planes. We also measured the faraday effect of opals immersed in a magneto-optically active liquid. It was shown that the behavior of the faraday rotation spectrum of the system of the opal sample and magneto-optically active liquid directly interrelates with transmittance anisotropy of the opal sample. The photonic band structure, transmittance and Faraday rotation of the light in three-dimensional magnetophotonic crystals of simple cubic and face centered cubic lattices formed from magneto-optically active spheres where studied by the layer Korringa-Kohn-Rostoker method. We found that a photonic band structure is most significantly altered by the magneto-optical activity of spheres for the high-symmetry directions where the degeneracies between TE and TM polarized modes for the corresponding non-magnetic photonic crystals exist. The significant enhancement of the Faraday rotation appears for these directions in the proximity of the band edges, because of the slowing down of the light. New approaches for one-dimensional magnetophotonic crystals fabrication optimized for the magneto-optical Faraday effect enhancement are proposed and realized. One-dimensional magnetophotonic crystals utilizing the second and the third photonic band gaps optimized for the Faraday effect enhancement have been successfully fabricated. Additionally, magnetophotonic crystals consist of a stack of ferrimagnetic Bi-substituted yttrium-iron garnet layers alternated with dielectric silicon oxide layers of the same optical thickness. High refractive index difference provides the strong spatial localization of the electromagnetic field with the wavelength corresponding to the long-wavelength edge of the photonic band gap.