• Nutrition Research and Practice
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• v.10 no.6
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• pp.575-582
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• 2016

BACKGROUNG/OBJECTIVES: The study was performed to investigate the effects and mechanisms of action of high maysin corn silk extract on body weight and fat deposition in experimental animals. MATERIALS/METHODS: A total of 30 male C57BL/6J mice, 4-weeks-old, were purchased and divided into three groups by weight using a randomized block design. The normal-fat (NF) group received 7% fat (diet weight basis), the high-fat (HF) group received 25% fat and 0.5% cholesterol, and the high-fat corn silk (HFCS) group received high-fat diet and high maysin corn silk extract at 100 mg/kg body weight through daily oral administration. Body weight and body fat were measured, and mRNA expression levels of proteins involved in adipocyte differentiation, fat accumulation, fat synthesis, lipolysis, and fat oxidation in adipose tissue and the liver were measured. RESULTS: After experimental diet intake for 8 weeks, body weight was significantly lower in the HFCS group compared to the HF group (P < 0.05), and kidney fat and epididymal fat pad weights were significantly lower in the HFCS group compared to the HF group (P < 0.05). In the HFCS group, CCAAT/enhancer binding protein-${\beta}$, peroxisome proliferator-activated receptor-${\gamma}1$ (PPAR-${\gamma}1$), and PPAR-${\gamma}2$ mRNA expression levels were significantly reduced (P < 0.05) in the epididymal fat pad, whereas cluster of differentiation 36, lipoprotein lipase, acetyl-CoA carboxylase-1, sterol regulatory element binding protein-1c, pyruvate dehydrogenase kinase, isozyme-4, glucose-6-phosphate dehydrogenase, and stearoyl-CoA desaturase-1 mRNA expression levels were significantly decreased in liver and adipose tissues (P < 0.05). In the HFCS group, mRNA expression levels of AMP-activated protein kinase, hormone-sensitive lipase, and carnitine palmitoyltransferase-1 were elevated (P < 0.05). CONCLUSIONS: It can be concluded that high maysin corn silk extract inhibits expression of genes involved in adipocyte differentiation, fat accumulation, and fat synthesis as well as promotes expression of genes involved in lipolysis and fat oxidation, further inhibiting body fat accumulation and body weight elevation in experimental animals.

• Korean Journal of Construction Engineering and Management
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• v.20 no.5
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• pp.21-30
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• 2019

Environmental and energy issues such as abnormal climate and depletion of fossil fuel due to global warming have emerged as a critical task to threaten human survival. As a result, interest in the Zero Energy Building is increasing as it is an innovative building that can significantly contribute to building energy reduction and greenhouse gas reduction. In the market, however, the added cost of construction is a major stumbling block to the revitalization of the Zero Energy certification. In this study, general private apartment complexes were selected for research, detailed elements for Zero Energy certification were presented based on the construction criteria for eco-friendly houses from the initial design stage, and the cost efficiency analysis of the components for certification were presented. It has been analyzed that only Grade 3 certification can be implemented in apartments due to technical level and physical limitations. Also, after reviewing the cost trend during the lifecycle cost, all expenses can be recovered within 13 years after completion only in the case of grade 5 of the Zero Energy Building. The additional costs proposed in the present study are reflected appropriately in the review of projects for apartments scheduled for order in the future to contribute to the revitalization of the Zero Energy Building certification.

• Applied Biological Chemistry
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• v.17 no.1
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• pp.31-41
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• 1974

This study was conducted to determine the effects of soybean cultivation on yield and other characters in a newly reclaimed soil. Four factois - (1) plant density (2) compost application (3) innoculation of nodule bacteria (Rhizobium japonicum) combined with lime application (4) NPK application-were examined in a 24 factorial experiments arranged in randomized complete block design with 4 replicates. Kangio variety was used and the results obtained are summarized as follows; (1) Dense plant population, Application of Compost and application of fertilizer (NPK) gave the yields 1.7, 1.4 and 2.1 times the check respectively. The Combinations of, dense $population{\times}compost$, dense $compost{\times}fertilizer$ (NPK), $population{\times}compost{\times}fertilizer$ (NPK), and dense $population{\times}compost{\times}nodule$ bacteria with $lime{\times}fertilizer$ (NPK) increased the yields by 2.0, 3.0, 2.6 and 5.4 times than the check respectively. But little effect on yield was noted in the treatment inoculated with nodule bacteria with lime. (2) In the case of higher yield, the increased weight of 100 seeds was found. (3) A markedly increased PH was observed in all of the plots under study after the completion of experiment. (4) The compost treatment and the ferttilizer (NPK) treatment greatly increased the organic matter, total nitrogen and the available phosphorus in the soil. (5) The variation in the grain yield appeared to have a close correlation with the content of available $P_2O_5$ in the soil.

• Asian-Australasian Journal of Animal Sciences
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• v.15 no.10
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• pp.1422-1427
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• 2002

Fifteen crossbred cattle bulls of about 22-24 months age (mean body weight ranged from 291.0 to 298.1 kg) were randomly divided into 3 groups of 5 animals following randomized block design. Animals in group 1 were fed concentrate mixture containing wheat bran 97%, mineral mixture 2% and salt 1% plus ad libitum chopped green sugarcane tops (SCT) as a roughage source. Animals in group 2 were fed concentrate mixture containing lentil chuni 97%, mineral mixture 2% and salt 1% while group 3 concentrate contained wheat bran 48.5%, lentil chuni 48.5%, mineral mixture 2% and salt 1% plus ad libitum chopped green SCT to meet their maintenance requirements. During metabolism trial period, the mean total intake and digestibility of DM in groups 1, 2 and 3 was $8.09{\pm}0.41$, $8.41{\pm}0.49$ and $7.86{\pm}0.16kg/d$ and 60.24, 63.24 and 65.05%, respectively. The intake of CP (p<0.05) and EE (p<0.01) was significantly higher in group 2 and group 1, respectively as compared to remaining 2 groups, which were comparable. Digestibility of CP and EE was significantly (p<0.01) higher in group 3 and that of CP was comparable with group 2. The intake and digestibility of total carbohydrates, NDF, ADF, Hemi-cellulose and cellulose were similar among 3 groups. The mean body weight changes in group 1, 2 and 3 were 173.4, 253.4 and 203.4 g/d, respectively, which was significantly (p<0.05) higher in group 2. The total nitrogen (N) and phosphorus (P) intakes were significantly higher in group 2 and group 1, respectively. The total volatile fatty acids, ammonia-N, trichloro-acetic acid precipitable nitrogen (TCA ppt.-N; p<0.05), total-N concentrations and pH were significantly (p<0.01) higher in group 3, however, pH and TCA ppt.-N was comparable with group 2 and 1, respectively. From the results, it may be deduced that the feeding of chopped green SCT supplemented with a concentrate mixture having both wheat bran (48.5%) and lentil chuni (48.5%) has shown a better performance with respect to intake and digestibility of nutrients and growth as well.

• Journal of Animal Science and Technology
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• v.66 no.1
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• pp.145-155
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• 2024

This study was conducted to determine the effects of amino acid (AA) supplementation in low-protein (LP) diets on growth performance and nitrogen (N) excretion. A total of 175 7-day-old Ross 308 male broilers, with a mean body weight (BW) of 165 g (standard deviation = 11.2 g), were grouped into five blocks by BW and allocated to seven treatments according to a randomized complete block design with five replicate cages at five birds per cage. Dietary treatments comprised a control diet containing 20.0% crude protein (CP) and six LP diets containing either 18.5% or 17.0% CP. These LP diets were supplemented with either no AA supplementation, indispensable AA, or both indispensable and dispensable AA (glutamic acid and glycine). Birds were fed experimental grower diets from day 7 to 21 and then commercial finisher diets until day 28. During the grower period (day 7 to 21), birds fed LP diets supplemented with indispensable AA exhibited greater (p < 0.05) BW, body weight gain (BWG), feed intake (FI), and gain-to-feed ratio (G:F) than birds fed LP diets without crystalline AA and were comparable to birds fed the control diet. During the finisher period (day 21 to 28), birds fed LP diets supplemented with indispensable AA showed greater (p < 0.05) BW than birds fed LP diets without crystalline AA, and their growth performance was comparable to birds fed the control diet. Throughout the overall period, supplementing indispensable AA in LP diets resulted in elevated (p < 0.05) BWG, FI, and G:F more than those of LP diets without crystalline AA and were comparable to those of the control diet. Supplementing indispensable AA in LP diets decreased amount and coefficient of N excretion as much as the control diet. Dispensable AA supplementation in LP diets did not influence growth performance and N excretion. In conclusion, supplementing indispensable AA in LP diets maintains growth performance and N excretion until the dietary CP lowers from 20.0% to 17.0% during the grower period. As long as dietary CP is above 17.0%, dispensable AA may not be deficient in LP diets during the grower period.

• Journal of the Institute of Electronics Engineers of Korea SD
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• v.44 no.12
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• pp.54-60
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• 2007

This paper proposes a built-in-self-repair (BISR) structure using 2-dimensional spare memory to effectively self-repair faults of an embedded memory. In case of multiple faults in the same row (column) of an embedded memory, the previous method using 1-D spare column (row) memory needs the same number of spare memory columns (rows) as the number of faults to self-repair them. while the new method using 2-D spare memory needs only one spare row (column) to self-repair them. Also, the virtual divided memory is adopted to be able to self-repair using not a full spare column memory but the only partial spare column memory corresponding to the faults. A self-repair circuit with $64\times1-bit$ core memory and $2\times8$ 2-D spare memory is designed. And the circuit includes a built-in-self-test block using the 13N March algorithm. The circuit has been implemented using the $0.25{\mu}m$ MagnaChip CMOS process and has $1.1\times0.7mm^2$ chip area with 10,658 transistors.

• Journal of the Korean GEO-environmental Society
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• v.8 no.6
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• pp.53-60
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• 2007

L/EPS, manufactured in the shape of block and used for civil engineering, is a lightweight material with an excellent resistance to compression, and provides a superb self-sufficient stability. EPS is a suitable material capable of resolving the problem of settlement and lateral flow if it is applied as the soil on soft ground. The Korean Standards (KS) has not yet proposed any testing method for use of EPS as an engineering banking material. Only its testing and quality ordinance as a heat insulation material has been standardized. The design criteria for EPS has been established and applied through the trial construction of KHC (Korea Highway Corporation) and quality test of manufacturer, but most studies on them have been confined to factory products. This study is focused on comparing and analyzing long-term durability by conducting cyclic load test, freezing and thawing test, absorption rate test and others. EPS used in the test was chosen from construction sites and factory products, focusing on the long-term durability of EPS depending on the passage of time. Unconfined compression test results indicated that the strength of collected samples was lower than factory products. While the triaxial compression test results indicated that the shear strength increased in proportion to the increase of confining pressure, and factory products had declining shear strength as the confining pressure rose.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.22 no.1
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• pp.100-108
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• 2018

This paper describes a design of scalable RSA public-key cryptography processor supporting four key lengths of 512/1,024/2,048/3,072 bits. The modular multiplier that is a core arithmetic block for RSA crypto-system was designed with 32-bit datapath, which is based on the CIOS (Coarsely Integrated Operand Scanning) Montgomery modular multiplication algorithm. The modular exponentiation was implemented by using L-R binary exponentiation algorithm. The scalable RSA crypto-processor was verified by FPGA implementation using Virtex-5 device, and it takes 456,051/3,496347/26,011,947/88,112,770 clock cycles for RSA computation for the key lengths of 512/1,024/2,048/3,072 bits. The RSA crypto-processor synthesized with a $0.18{\mu}m$ CMOS cell library occupies 10,672 gate equivalent (GE) and a memory bank of $6{\times}3,072$ bits. The estimated maximum clock frequency is 147 MHz, and the RSA decryption takes 3.1/23.8/177/599.4 msec for key lengths of 512/1,024/2,048/3,072 bits.

• The Journal of the Korea Contents Association
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• v.18 no.1
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• pp.164-172
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• 2018

This study explores how to implement a learning experience-based professionalism program for a medical students and evaluates its program through effectiveness and usability test. This study aims to provide practical implications for experience-based learning in an undergraduate level. Seventy four first-year medical students enrolled in PDS1(Patient-Doctor-Society 1): professionalism, one-week block (30 hours), one-credit program based on a experience-based learning model. All of the students were given six learning themes and learning resources and supporting tools, and conducted stepwise learning activities; preparation, organization, sharing, reflection and evaluation of experiences. The effectiveness of learning was evaluated by comparing the pre and post results of student's self-assessment on 24 questionnaire items about professionalism. After the course, the students and instructors conducted a usability evaluation of the program through questionnaires or group interviews. Learners' self-assessment results of professionalism such as leadership, self-directed learning, professional attitude, and social accountability all showed significant differences between the pre- and post-test. Satisfaction of the program was distributed to 3.58~3.78 according to items. Instructors and learner interviews confirmed practical usability throughout the course design, implementation and students evaluation. The results of the study showed the feasibility of implementing learning experience-based professionalism program in medical school. This study provides practical implications to develope and evaluate the learning experience-based professionalism program in medical education.

• Animal Bioscience
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• v.36 no.1
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• pp.119-131
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• 2023

Objective: This study was to assess the effects of different doses of an essential oil blend (EOB) on growth performance, diarrhea occurrence (DO), hematological and blood biochemical profile, intestinal morphometry, morphology and microbiology, relative weight and length of organs, digestive content pH, and liver antioxidant status in weaning piglets. Methods: A total of 135 barrows (7.09±0.29 kg body weight) were allotted randomly in a randomized complete block design based on body weight with nine replications and three animals per pen. Dietary treatments were a negative control (NC): basal diet; positive control (PC): NC plus 125 mg performance-enhancing antibiotic (enramycin 8%)/kg diet; NC plus 100 mg EOB/kg diet (EO100); NC plus 200 mg EOB/kg diet (EO200); and NC plus 400 mg EOB/kg diet (EO400). Diarrhea occurrence was monitored daily, and performance at the end of each phase. Results: Gain to feed ratio was greater (p<0.05) in starter II pigs fed EO400 and EO200 than in those fed EO100. Pigs fed EO400 had lower (p<0.05) DO than those fed NC and EO100 in the total period. Pre-starter II pigs fed NC had (p<0.05) lower serum total protein and plasma protein than pigs fed PC. Pigs fed EO100 showed smaller (p<0.05) mean corpuscular volume (MCV) than pigs fed EO400. Starter II pigs fed EO400 had (p<0.05) greater MCV and lower mean corpuscular hemoglobin and erythrocytes than those fed EO100. There was a greater concentration (p<0.05) of band cells for PC, similar to EO400 and EO200. Performance-enhancing antibiotic and EOB to diets increased (p<0.05) liver superoxide dismutase activity. Conclusion: Adding 200 and 400 mg EOB/kg diet decreased DO and was advantageous to hematological and blood biochemical profile and liver antioxidant status without being detrimental to growth performance and gastrointestinal health in nursery pigs.