The multi-level storage architecture has been widely adopted in servers and data centers. However, while prefetching has been shown as a crucial technique to exploit sequentiality in accesses common for such systems and hide the increasing relative cost of disk I/O, existing multi-level storage studies have focused mostly on cache replacement strategies. In this paper, we show that prefetching algorithms designed for single-level systems may have their limitations magnified when applied to multi-level systems. Overly conservative prefetching will not be able to effectively use the lower-level cache space, while overly aggressive prefetching will be compounded across levels and generate large amounts of wasted prefetch. We design and implement a hierarchy-aware lower-level prefetching strategy called PMS(Prefetching strategy for Multi-level Storage system) that applicable to any upper level prefetching algorithms. PMS does not require any application hints, a priori knowledge from the application or modification to the va interface. Instead, it monitors the upper-level access patterns as well as the lower-level cache status, and dynamically adjusts the aggressiveness of the lower-level prefetching activities. We evaluated the PMS through extensive simulation studies using a verified multi-level storage simulator, an accurate disk simulator, and access traces with different access patterns. Our results indicate that PMS dynamically controls aggressiveness of lower-level prefetching in reaction to multiple system and workload parameters, improving the overall system performance in all 32 test cases. Working with four well-known existing prefetching algorithms adopted in real systems, PMS obtains an improvement of up to 35% for the average request response time, with an average improvement of 16.56% over all cases.
Journal of the Korea Society of Computer and Information
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v.26
no.10
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pp.125-137
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2021
This study was intended to develop a prototype of new Hanbok Cheollik one-piece based on design extracted through a preference survey on new Hanbok Cheollik one-piece. Through this, it was intended to provide information on patterns that are fundamental to the production of new Hanbok Cheollik one piece. The pattern of the experiment was produced by modifying D pattern, which was selected as excellent in the comparison of commercial Cheollik one-piece patterns. The SPSS 26.0 program was used to analyze the appearance evaluation of patterns. As a result of the 1st evaluation of appearance and garment pressure, the shoulder, sleeve length, skirt length and sleeve width required modification, reducing the sleeve length by 8.0cm and the sleeve width by 1.0cm in total. The length of the skirt was reduced by 5.0cm and the shoulder end point was reduced by 0.5cm on both sides to modify the shoulder width. As a result of the 2nd evaluation, the waist area, sleeve width, and skirt wrinkles were required to be corrected, reducing 2.0 cm waist width and 1.0 cm sleeve width and removing wrinkles on the front center and side area. The final pattern was highly appreciated. In future studies, it is thought that research should be conducted through study of Cheollik one-piece pattern according to material and age and the actual wearing experiment according to fabric and age.
This research is to anticipate problems of Ray's disabled experiment welfare vehicles for 17 drivers with disability, improving them. In addition it is to provide the criteria for ergonomic design based on perspective of drivers with disability by investigating 18 items of usability test. The results are as follows. First, satisfaction degree of Ray, disabled experiment welfare vehicle, was shown to be 3.88 which is higher than normal vehicles whose degree is 3.20. This showed that the disabled experiment welfare vehicle is the one with much improvement. Second, so as to develop a welfare vehicle it needs to take into account some factors including rear slope, wheelchair locker, seat belt, safety grip, and high roof. Third, in case of rear slope, high roof and width of manual or automatic wheel chairs should be considered and motor-operated device should also be taken into account for safety lockers, which make a wheelchair firmly fixed. Moreover, motor-operated seat and rear slope can be chosen for either of the disabled and the elderly.
Roolf, Catrin;Saleweski, Jan-Niklas;Stein, Arno;Richter, Anna;Maletzki, Claudia;Sekora, Anett;Escobar, Hugo Murua;Wu, Xiao-Feng;Beller, Matthias;Junghanss, Christian
Biomolecules & Therapeutics
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v.27
no.5
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pp.492-501
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2019
Nitrogen-containing heterocycles such as quinoline, quinazolinones and indole are scaffolds of natural products and have broad biological effects. During the last years those structures have been intensively synthesized and modified to yield new synthetic molecules that can specifically inhibit the activity of dysregulated protein kinases in cancer cells. Herein, a series of newly synthesized isoquinolinamine (FX-1 to 8) and isoindoloquinazolinone (FX-9, FX-42, FX-43) compounds were evaluated in regards to their anti-leukemic potential on human B- and T- acute lymphoblastic leukemia (ALL) cells. Several biological effects were observed. B-ALL cells (SEM, RS4;11) were more sensitive against isoquinolinamine compounds than T-ALL cells (Jurkat, CEM). In SEM cells, metabolic activity decreased with $10{\mu}M$ up to 26.7% (FX-3), 25.2% (FX-7) and 14.5% (FX-8). The 3-(p-Tolyl) isoquinolin-1-amine FX-9 was the most effective agent against B- and T-ALL cells with IC50 values ranging from 0.54 to $1.94{\mu}M$. None of the tested compounds displayed hemolysis on erythrocytes or cytotoxicity against healthy leukocytes. Anti-proliferative effect of FX-9 was associated with changes in cell morphology and apoptosis induction. Further, influence of FX-9 on PI3K/AKT, MAPK and JAK/STAT signaling was detected but was heterogeneous. Functional inhibition testing of 58 kinases revealed no specific inhibitory activity among cancer-related kinases. In conclusion, FX-9 displays significant antileukemic activity in B- and T-ALL cells and should be further evaluated in regards to the mechanisms of action. Further compounds of the current series might serve as templates for the design of new compounds and as basic structures for modification approaches.
The purpose of this study was to understand educational changes and effects of cognitive behavioral art therapy using the smart device. The participant of the study was a 4th grade of male elementary school student who had aggressiveness and impulsiveness with emotional instability. The study was conducted one to two times a week for six months with a total of 30 educational sessions. Among 80 minutes per session, 60 minutes of art therapy and 20 minutes of cognitive behavioral therapy were applied, and during the sessions, cognitive action art therapy (drawing and shaping activities), cognitive restructuring, behavioral modification, systemic dullness, social skills training, empathy and landscaping training were applied. For the numeral assessment, Traffic Anxiety Inventory for Children (TAIC), Beck Anxiety Inventory (BAI) and emotional instability measures were used. Research showed that cognitive behavioral art therapy using smart devices had the effect of positive emotional change in children with emotional anxiety, and based on this, future development directions including systematic instructional design, scientific analysis and feedback technologies were discussed.
Bae, Jang Won;Choi, Seon Han;Lee, Chun-Hee;Paik, Euihyun
Journal of the Korea Society for Simulation
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v.30
no.1
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pp.103-112
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2021
In recent years, public bicycle systems are widely spread over the world according to the development of ICT technology. Since the public bicycle systems in large cities need to secure both publicity and convenience for citizens, analysis of various their issues from introduction to operation is required. In addition, it is also necessary to prepare for various scenarios for coexistence with the PM business, which is recently in the spotlight as a last mile means and normally managed privately. This paper introduces modeling and simulation for efficient operations of public bicycle systems. In particular, the proposed method was developed in a form that can be easily used in other cities by modeling the general structure and behavior of the public bicycle system, and it was developed to facilitate modification and expansion of the future model with a component-based model configuration. This paper provides a case study of the propose method, which is the public bicycle simulation in Sejong City. The simulation results were derived by applying the data from the public bicycle system of Sejong City, and they were verified with the associated real data of Sejong City. Using the verified model, it is expected that it can be used as a tool to design and analyze various services on the public bicycle systems, which were especially suitable for Sejong City.
Objective: In this study we aimed to evaluate the effect of dietary live yeast supplementation on ruminal pH pattern, fermentation characteristics and associated bacteria in beef cattle. Methods: This work comprised of in vitro and in vivo experiments. In vitro fermentation was conducted by incubating 0%, 0.05%, 0.075%, 0.1%, 0.125%, and 0.15% active dried yeast (Saccharomyces cerevisiae, ADY) with total mixed ration substrate to determine its dose effect. According to in vitro results, 0.1% ADY inclusion level was assigned in in vivo study for continuously monitoring ruminal fermentation characteristics and microbes. Six ruminally cannulated steers were randomly assigned to 2 treatments (Control and ADY supplementation) as two-period crossover design (30-day). Blood samples were harvested before-feeding and rumen fluid was sampled at 0, 3, 6, 9, and 12 h post-feeding on 30 d. Results: After 24 h in vitro fermentation, pH and gas production were increased at 0.1% ADY where ammonia nitrogen and microbial crude protein also displayed lowest and peak values, respectively. Acetate, butyrate and total volatile fatty acids concentrations heightened with increasing ADY doses and plateaued at high levels, while acetate to propionate ratio was decreased accordingly. In in vivo study, ruminal pH was increased with ADY supplementation that also elevated acetate and propionate. Conversely, ADY reduced lactate level by dampening Streptococcus bovis and inducing greater Selenomonas ruminantium and Megasphaera elsdenii populations involved in lactate utilization. The serum urea nitrogen decreased, whereas glucose, albumin and total protein concentrations were increased with ADY supplementation. Conclusion: The results demonstrated dietary ADY improved ruminal fermentation dose-dependently. The ruminal lactate reduction through modification of lactate metabolic bacteria could be an important reason for rumen pH stabilization induced by ADY. ADY supplementation offered a complementary probiotics strategy in improving gluconeogenesis and nitrogen metabolism of beef cattle, potentially resulted from optimized rumen pH and fermentation.
Journal of Korea Entertainment Industry Association
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v.14
no.6
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pp.289-299
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2020
The purpose of this study was to confirm the effect of mindfulness education on perceived stress, mindfulness, psychological well-being, and brain waves. The study used a repeated-measures design to examine 42 female university students currently enrolled in mindfulness courses. Subjects participated in the mindfulness course once a week for eight weeks, 50 minutes per session. The main outcome variables, such as perceived stress, mindfulness, and psychological well-being, were measured with a structured questionnaire and brain waves were measured with an electroencephalograph. The same variables were then measured after the completion of the eight-week course. The results demonstrate that perceived stress significantly decreased from 1.85±0.39 to 1.66±0.39 points (t=3.44, p=.001), while, on the other hand, mindfulness increased from 3.10±0.26 points to 3.19±0.32 points (t =-2.78, p=.008). There was also a significant difference in the level of autonomy, a subcategory of psychological well-being (t=-2.70, p=.010). In addition, EEG indicated significant changes in the frequencies of Theta channel 19 and Rapid Alpha channels 7 and 10. These results suggest that further studies are needed to elucidate the effects of mindfulness education through the modification of mindfulness course plans, diversification of teaching methods, and improvement in the educational environment.
Kim, Sung-Il;Lee, Jungwhee;Lee, Pil-Goo;Kim, Choong-Eon
KSCE Journal of Civil and Environmental Engineering Research
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v.30
no.6A
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pp.535-542
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2010
Precise estimation of a structure's dynamic characteristics is indispensable for ensuring stable dynamic responses during lifetime especially for the structures which can experience resonance such as railway bridges. In this paper, the results of forced vibration tests of different excitation methods (vibration exciter and impact hammer) are compared to examine the differences and the cause of differences of extracted natural frequencies. Consequently a natural frequency modification method is suggested to eliminate effects of non-structural disturbance factors. Also, sequential forced vibration tests are performed before and after track construction according to the construction stage of a railway bridge, and the variation of natural frequencies are examined. Effect of added mass of vibration exciter and variation of support condition due to the level of excitation force are concluded as the major cause of natural frequency differences. Thus eliminating these effects can enhance the reliability of the extracted natural frequencies. Construction of track affects not only the mass of structure but also the stiffness of the structure. Also, the amount of increase in stiffness varies according to the level of structural deflection. Therefore, reasonable estimation of the level of structural response during operation is important for precise natural frequency calculation at design phase.
The Journal of Korea Institute of Information, Electronics, and Communication Technology
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v.16
no.6
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pp.385-391
/
2023
As the use of electric vehicles has increased to minimize carbon emissions, the analyzing the state and performance of lithium-ion batteries that is instrumental in electric vehicles have been important. Comprehensive analysis using not only the voltage, current and temperature of the battery pack, which can affect the condition and performance of the battery, but also the driving data and charging pattern data of the electric vehicle is required. Therefore, a thorough analysis is imperative, utilizing electric vehicle operation data, charging pattern data, as well as battery pack voltage, current, and temperature data, which collectively influence the condition and performance of the battery. Therefore, collection and preprocessing of battery data collected from electric vehicles, collection and preprocessing of data on driver driving habits in addition to simple battery data, detailed design and modification of artificial intelligence algorithm based on the analyzed influencing factors, and A battery analysis and evaluation model was designed. In this paper, we gathered operational data and battery data from real-time electric buses. These data sets were then utilized to train a Random Forest algorithm. Furthermore, a comprehensive assessment of battery status, operation, and charging patterns was conducted using the explainable Artificial Intelligence (XAI) algorithm. The study identified crucial influencing factors on battery status, including rapid acceleration, rapid deceleration, sudden stops in driving patterns, the number of drives per day in the charging and discharging pattern, daily accumulated Depth of Discharge (DOD), cell voltage differences during discharge, maximum cell temperature, and minimum cell temperature. These factors were confirmed to significantly impact the battery condition. Based on the identified influencing factors, a battery analysis and evaluation model was designed and assessed using the Random Forest algorithm. The results contribute to the understanding of battery health and lay the foundation for effective battery management in electric vehicles.
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