• Animal Bioscience
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• v.36 no.10
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• pp.1517-1529
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• 2023

Objective: The objective of this study was to investigate the phylogenetic and expression analysis of the angiopoietin-like (ANGPTL) gene family and their role in lipid metabolism in pigs. Methods: In this study, the amino acid sequence analysis, phylogenetic analysis, and chromosome adjacent gene analysis were performed to identify the ANGPTL gene family in pigs. According to the body weight data from 60 Jinhua pigs, different tissues of 6 pigs with average body weight were used to determine the expression profile of ANGPTL1-8. The ileum, subcutaneous fat, and liver of 8 pigs with distinct fatness were selected to analyze the gene expression of ANGPTL3, ANGPTL4, and ANGPTL8. Results: The sequence length of ANGPTLs in pigs was between 1,186 and 1,991 bp, and the pig ANGPTL family members shared common features with human homologous genes, including the high similarity of the amino acid sequence and chromosome flanking genes. Amino acid sequence analysis showed that ANGPTL1-7 had a highly conserved domain except for ANGPTL8. Phylogenetic analysis showed that each ANGPTL homologous gene shared a common origin. Quantitative reverse-transcription polymerase chain reaction analysis showed that ANGPTL family members had different expression patterns in different tissues. ANGPTL3 and ANGPTL8 were mainly expressed in the liver, while ANGPTL4 was expressed in many other tissues, such as the intestine and subcutaneous fat. The expression levels of ANGPTL3 in the liver and ANGPTL4 in the liver, intestine and subcutaneous fat of Jinhua pigs with low propensity for adipogenesis were significantly higher than those of high propensity for adipogenesis. Conclusion: These results increase our knowledge about the biological role of the ANGPTL family in this important economic species, it will also help to better understand the role of ANGPTL3, ANGPTL4, and ANGPTL8 in lipid metabolism of pigs, and provide innovative ideas for developing strategies to improve meat quality of pigs.

• The Journal of Korean Academic Society of Nursing Education
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• v.29 no.2
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• pp.124-137
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• 2023

Purpose: This study's aim was to confirm the importance and performance of the clinical practice of nurses working in the general wards of a tertiary hospital and to analyze their educational needs. Methods: The study employed a descriptive research design, and a self-reported questionnaire was developed and used for nurses in a tertiary hospital. Data were collected from July 22 to July 29, 2022, analyzed by an independent t-test, paired t-test, and one-way ANOVA for the importance and performance of each clinical nursing practice according to general characteristics, and then a post hoc verification was performed by Scheffé's test. An Importance-Performance Analysis and Borich needs assessment model were used to analyze clinical nursing education needs. Results: Clinical nursing practice performance showed a significant difference according to length of total clinical career, time working in current department, and preceptor experience. According to the results of the Importance-Performance Analysis, neurological evaluation, and nursing intervention, artificial respirator and high-flow oxygen inhalation nursing, chemotherapy, emergency nursing, and cardiopulmonary resuscitation were identified as belonging to the "concentrate here" quadrant. All these items ranked in the top 10 in the Borich needs assessment model. Conclusion: Based on these results, the current education system should be reviewed, and short and long term education strategies based on educational needs should be established to strengthen the competence of nurses.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.28 no.1B
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• pp.11-20
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• 2008

The spillway type of small and midsize dams in Korea is almost overflow weir. To examine flood control capacity of overflow spillway, FLOW-3D was applied to Daesuho dam and analysis was focused on the discharge of dam spillway by changing weir shape. Overflow phases and discharges of linear labyrinth weir and curved labyrinth weir were compared with those of existing linear ogee weir. Hydraulic model experiment was performed to verify numerical result. Verification results showed that overflow behaviors and flow characteristics in the side channel by hydraulic model experiment and numerical simulation are well matched, and water surface elevation at side wall coincides with each other. When the reservoir elevation was increased up to design flood level, in case of the linear ogee weir the flow over the crest ran through smoothly in the side channel, whereas in cases of linear labyrinth weir and curved labyrinth weirs, the flow discharge was increased by 40 cms, and the flow over the weir crest, rotating counter-clockwise, was submerged in the side channel. The results of the water level-discharge curve revealed that labyrinth weir can increase discharge by 71% compared to the discharge of linear ogee weir at low reservoir elevation since it can have longer effective length. But as water surface elevation rises, the slope of water level-discharge curve of labyrinth weir becomes milder by submergence and nappe interference in the side channel.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.26 no.2A
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• pp.301-310
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• 2006

Carbon fiber reinforced polymer (CRFP) materials are well suited to the rehabilitation of civil engineering structures due to their corrosion resistance, high strength to weight ratio and high stiffness to weight ratio. Their application in the field of the rehabilitation of concrete structures is increased due to the vast number of bridges and buildings in need of strengthening. However, RC members, strengthened with externally bonded CFRP plates, happened to collapse before reaching the expected design failure load. Therefore, it is necessary to develop the new strengthening method to overcome the problems of previous bonded strengthening method. This problems can be solved by prestressing the CFRP plate before bonding to the concrete. In this study, a total of 21 specimens of 3.3 m length were tested by the four point bending method after strengthening them with externally bonded CFRP plates. The CFRP plates were bonded without prestress and with various prestress levels ranging from 0.4% to 0.8% of CFRP plate strain. All specimen with end anchorage failed by a plate fracture regardless of the prestress levels while the specimen without end anchorage failed by the separation of the plate from the beam due to premature debonding. The cracking loads was proportionally related to the prestress levels, but the maximum loads of specimens strengthened with prestressed CFRP plates were insignificantly affected by the prestress levels.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.30 no.2D
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• pp.153-161
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• 2010

The city planning of a local government is a continuous process that does not end with the creation of a plan but proceeds through decision-making, monitoring and evaluation phases. As a new city planning is changed and confirmed, there is a chance to construct a large scale road that is connected with an under constructed road. In this case, the expansion of the width and length of road, the addition of bridges or tunnels, and the change of the size and location of interchanges lead to many changes on road design and construction. In the past, the consignment contracts for a road construction have been made in limited numbers and for limited civil works. Now, it is growing in numbers and is making for large scale multi-works. However, the standard process and guidelines for the consignment contracts have not been suggested yet, so there is difficulty in performing the consigned road construction effectively. In this paper, the important factors for the consignment contracts are determined by construction document reviews and expert interviews. Based on these results, a standard process for the consigned contracts and a guideline for agreeing on construction cost are suggested. The costs that should be paid by a consignor are also defined.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.26 no.3B
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• pp.271-278
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• 2006

In design of groyne series, groyne spacing is a important factor and have an effect on not only the characteristics of backward and recirculation flow in groyne zone but also flow field in main channel. It is necessary study about flow pattern of recirculation zone and main channel that is a cause of bad change, local scour and bank erosion by groyne spacing. In this study, flow variation of groyne zone and main chanel for spacing of groynes were analyzed from the experiment results in order to offer a fundamental data that can be used to decide the proper groyne spacing. Experiments were conducted 12 cases for groyne spacing(L) by groyne length(l) rate and the velocity profile was measured using LSPIV and ADV. From the results, two vortex flows developed in recirculation zone for L/l=3~9 and three vortex flows developed over L/l=10. The velocity of backward flow in recirculation zone was decreased up to 20% over L/l=4. The velocity of main channel flow was increased from 1.3 to 2.0 times by groyne spacing and the rate of velocity increased by increasing groyne spacing. The maximum velocity occurred in 0.7~0.8 times of groyne spacing downstream of upper groyne.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.30 no.2A
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• pp.81-92
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• 2010

In design of steel frames, it is generally believed that elastic system buckling analysis cannot predict real behaviors of structures, while inelastic system buckling analysis can give informative buckling behaviors of individual members considering inelastic material behavior. However, the use of Euler buckling equation with these system buckling analyses have the inherent problem that the methods evaluate unexpectedly large effective lengths of members having relatively small axial forces. This paper proposes a new method of obtaining elastic and inelastic effective lengths of all members in steel frames. Considering a fictitious axial force factor for each story of frames, the proposed method determines the effective lengths using the inelastic stiffness reduction factor and the iterative eigenvalue analysis. In order to verify the validity of the proposed method, the effective lengths of example frames by the proposed method were compared to those of previously established methods. As a result, the proposed method gives reasonable effective lengths of all members in steel frames. The effect of inelastic material behavior on the effective lengths of members was also discussed.

• Journal of the Korean Society of Marine Environment & Safety
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• v.29 no.7
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• pp.971-979
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• 2023

Small ships (<499 GT) constitute 46% of the existing ships, therefore, it can be concluded that they produce relatively high CO₂ gas emissions. Operating in optimal trim conditions can reduce the resistance of the ship, which results in fewer greenhouse gases. An affordable way for trim optimization is to adjust the weight distribution to obtain an optimum longitudinal center of gravity (LCG). Therefore, in this study, the effect of LCG changes on the resistance of a small planing ship is studied using empirical and numerical analyses. The Savitsky method employing Maxsurf resistance and the STAR-CCM+ commercial computational fluid dynamics (CFD) software is used for the empirical and numerical analyses, respectively. Finally, the total resistance from the ship design process is compared to obtain the optimum LCG. To summarize, using numerical analysis, optimum LCG is achieved at the 46.2% length overall (LoA) at Froude Number 0.56, and 43.4% LoA at Froude Number 0.63, which provides a significant resistance reduction of 41.12 - 45.16% compared to the reference point at 29.2% LoA.

• Journal of Aerospace System Engineering
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• v.18 no.1
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• pp.53-63
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• 2024

Adopting an engine igniter with high efficiency and ignition performance is essential for reliable operation of liquid rocket engines. In this study, we developed a spark torch igniter for a 450 N-scale methane-oxygen liquid rocket engine by conducting numerical analyses, igniter manufacturing and validation. Specifically, we conducted a parametric study for maximizing the enthalpy at the igniter exit, specifically by adjusting the mass flow rate, nozzle area ratio, fuel-oxidizer mixture ratio, and the igniter length-to-diameter. The heat transferred via the igniter nozzle exit was computed using 3-dimensional numerical simulations. We also manufactured and tested the igniter based on a deduced design to confirm ignition performance of the designed spark torch igniter. The igniter developed through this study could contribute to the development of practical propulsion systems such as upper-stage engines of small launch vehicles.

• Journal of the Korea institute for structural maintenance and inspection
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• v.28 no.2
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• pp.61-68
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• 2024

The majority of high-speed railway bridges along the domestic Gyeongbu and Honam lines feature a PSC-box type structure with a span length ranging from 35 to 40m, which typically exhibits a first bending natural frequency of approximately 4 to 5Hz. When KTX high-speed trains transverse these bridges at speeds ranging from 290 to 310km/h, the vibration induced by the trains approaches the first bending natural frequency of the bridge. Furthermore, with the upcoming operation of a EMU-320 high-speed train and the anticipated increase in the speeds of these high-speed trains, there is a need to analyze the dynamic response of high-speed railway bridges. For this, based on measured responses from actual railway bridges, a numerical model was constructed using a numerical model updating technique. The dynamic response of the updated numerical model exhibited a strong agreement with the measured response from the actual railway bridges. Subsequently, this updated model was utilized to analyze the dynamic response characteristics of the bridges when KTX and EMU-320 trains operate at increased speeds. The maximum vertical displacement and acceleration at the mid-span of the bridges were also compared to those specified in the railway design standard with the increasing speed of KTX and EMU-320.