• 한국전자파학회논문지
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• 제26권10호
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• pp.841-850
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• 2015

전자 및 전파 통신기술의 급속한 발전에 따라 인류는 정보통신의 커다란 혜택을 누릴 수 있게 되었다. 그러나 전자파환경은 보다 복잡해지고, 각종 전자기기를 비롯한 인체에 다양한 영향을 미치게 되어 ANSI, FCC, CISPR 등과 같은 국제기구에서는 다양한 전자파환경을 규제하고, 효율적인 제어 및 대책을 수립해 오고 있다. 본 논문에서는 방열 기능을 가지면서 고성능의 전파흡수체 제조 방법을 제안하고, 나아가 미래의 스마트 전파흡수체의 전망을 기술하였다. 산화철($Fe_2O_3$)과 세라믹의 혼합물을 고온 열처리한 후, 탄소 물질과 배합하여 저온 열처리하고, 개구를 형성하여 2~2.45 GHz에서 방열 기능을 가지면서 흡수능이 20 dB 이상인 고성능 전파흡수체를 개발하였다. 이 스마트 전파흡수체는 다양한 전자, 통신, 제어, 전파 시스템의 회로 및 부품 보호용 소재로 활용성이 높을 것으로 보인다.

• 한국미생물생명공학회:학술대회논문집
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• 한국미생물생명공학회 2004년도 Annual Meeting BioExibition International Symposium
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• pp.60-61
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• 2004

Metabolic engineering is now a well established discipline, used extensively to determine and execute rational strategies of strain development to improve the performance of micro-organisms employed in industrial fermentations. The basic principle of this approach is that performance of the microbial catalyst should be adequately characterised metabolically so as to clearlyidentify the metabolic network constraints, thereby identifying the most probable targets for genetic engineering and the extent to which improvements can be realistically achieved. In order to harness correctly this potential, it is clear that the physiological analysis of each strain studied needs to be undertaken under conditions as close as possible to the physico-chemical environment in which the strain evolves within the full-scale process. Furthermore, this analysis needs to be undertaken throughoutthe entire fermentation so as to take into account the changing environment in an essentially dynamic situation in which metabolic stress is accentuated by the microbial activity itself, leading to increasingly important stress response at a metabolic level. All too often these industrial fermentation constraints are overlooked, leading to identification of targets whose validity within the industrial context is at best limited. Thus the conceptual error is linked to experimental design rather than inadequate methodology. New tools are becoming available which open up new possibilities in metabolic engineering and the characterisation of complex metabolic networks. Traditionally metabolic analysis was targeted towards pre-identified genes and their corresponding enzymatic activities within pre-selected metabolic pathways. Those pathways not included at the onset were intrinsically removed from the network giving a fundamentally localised vision of pathway functionality. New tools from genome research extend this reductive approach so as to include the global characteristics of a given biological model which can now be seen as an integrated functional unit rather than a specific sub-group of biochemical reactions, thereby facilitating the resolution of complexnetworks whose exact composition cannot be estimated at the onset. This global overview of whole cell physiology enables new targets to be identified which would classically not have been suspected previously. Of course, as with all powerful analytical tools, post-genomic technology must be used carefully so as to avoid expensive errors. This is not always the case and the data obtained need to be examined carefully to avoid embarking on the study of artefacts due to poor understanding of cell biology. These basic developments and the underlying concepts will be illustrated with examples from the author's laboratory concerning the industrial production of commodity chemicals using a number of industrially important bacteria. The different levels of possibleinvestigation and the extent to which the data can be extrapolated will be highlighted together with the extent to which realistic yield targets can be attained. Genetic engineering strategies and the performance of the resulting strains will be examined within the context of the prevailing experimental conditions encountered in the industrial fermentor. Examples used will include the production of amino acids, vitamins and polysaccharides. In each case metabolic constraints can be identified and the extent to which performance can be enhanced predicted

• 한국산업보건학회지
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• 제5권2호
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• pp.200-211
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• 1995

This study was designed to evaluate the effects of temperature and humidity on the sampling efficiency of mixed organic vapors of l,2-DCE, benzene, and MIBK by 3 different types of diffusion monitors. Independent variables used for the study were temperatures ($25^{\circ}C$, $35^{\circ}C$), humidities (30%, 80%), and vapor concentrations (low, medium, and high). In addition, vapor concentrations measured by the traditional charcoal tube method were used as reference values and were compared with those of by diffusion monitors. The results were as follows: 1. The desorption efficiencies(DE) of 1,2-DCE and benzene from charcoal tubes and from diffusion monitors ranged from 98% to 105%. In contrast, the DEs of MIBK from charcoal tubes and diffusion monitors except DM1 ranged from 71% to 85%. The DE of MIBK from DM1 was 98%. 2. No statistically significant differences of 1,2-DCE concentrations and the sampling efficiencies regardless of temperatures and humidities studied between charcoal tube and 3 diffusion monitors were found. 3. At 80% humidity, increasing frequencies of 1,2-DCE breakthrough at higher temperature and higher vapor concentration measured by charcoal tubes were observed. 4. No statistically significant difference of benzene concentrations were found between charcoal tube and diffusion monitors except DM3. The sampling efficiencies of DM3 were statistically significantly lower at all experimental conditions except the $35^{\circ}C$ and 30% humidity condition. 5. No statistically significant difference of MIBK concentrations were found between charcoal tube and diffusion monitors except DM3. The sampling efficiencies of DM3 were statistically significantly higher at higher humidity conditions regardless of temperature. Although statistically not significant, sampling efficiency of MIBK showed positive correlation with humidity while negative correlation with concentration was observed. 6. For sampling 1,2-DCE and benzene, no significant variations of concentrations among three diffusion monitors regardless of temperature and humidity conditions were found. For MIBK sampling, however, wide variations with increasing humidity among diffusion monitors were obtained. In conclusion, this study suggests that diffusion monitors will be a reasonables substitute for the traditional charcoal tubes for sampling non-polar organic vapors at temperature and humidity conditions studied. For polar organic vapors, use of an alternative desorption solution other than CS2 is recommended because of its low desorption efficiency. In addition, since variable among diffusion monitors for polar organic vapors particularly at higher humidity conditions were observed, further study is recommended of the effects of humidity on the performance of diffusion monitors.

• 조형예술학연구
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• 제3권
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• pp.33-61
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• 2001

Dans les arts modernes, nous ressentons souvent un $probl\`{e}me$ $disloqu\'{e}par$ rapport aux humains. Ceci ne viendrait-il pas $peut-\^{e}tre$ do notre $pens\'{e}e$ dans l' $\'{e}change$ culturelle entre le monde et nous qui s' appuie trop une $temporalit\'{e}$ et logique? Cette $the\`{s}e$ approche ce $probl\`{e}me$ $\`{a}$ travers one perception anthropologique do monde, en $\'{e}tudiant$ les arts tridimensionnels avec ses $\'{e}schelles$ qui deviennes plus on plus agrandis. Maurice Merleau-Ponty, dans son livre 'la $ph\'{e}nom\'{e}nologie$ de la perception', bien $r\'{e}sumait$ une $intersubjectivit\'{e}$ entre l' espace et nous. Selon lui, l' homme prend conscience do la forme des objets avec son environnement parce quil est un corps on interaction avec eux. Donc nous $r\'{e}f\'{e}rons$ ce livre pour notre set. Et on essayera ici d' $\'{e}tudier$ le travail do Constantin Brancusi, de Alberto Giacometti, do Richard Serra et do quelques d' autres travaux d' artistes L' oeuvre do Brancusi 'la Colonne sans fin', la taille plus de 29 m, produit one impression sur le spectateur relativement $\grave{a}$ la forme continue et $r\'{e}p\'{e}t\'{e}e$ $\`{a}$ linfini de $mani\'{e}re$ unifome. La pratique de Giacometti qui tenait compte do son envergure et de la longueur do son corps ainsi que do distance et de la mesure do sos bras, Il $d\'{e}formait$ aussi les silhouettes et transformait les objects en les $\'{e}tirant$ dans la perspective. Rosalind Krauss parler $\`{a}$ loeuvre do Serra, dans son livre 'l' originalit de lavant-garde et sutres mythes modernistes' (pp. 319-333), le spectateur est toujours on mouvement on liaison entre l' horizon do corps et celui do monde. Cette $transitivit\'{e}$ abstraite $r\'{e}ciproque$ entre le regardeur et le $regard\'{e}$, qui est comme le sujet de nombreuses oeuvres do Serra. Cependant le Maximalisme est $\`{a}$ l' origine Minimalisme qui s' $\'{e}tend$ dans ses efforts $th\'{e}oriques$ jusqu' au l' espace architecturale. Ces sculptures do grandes dimensions so situent autour de $b\^{a}timent$ ou dans lespace environnementale, comme ils sent l' architecture et le paysage. On suppose ici, leurs concepts de l' espace $\'{e}largit$ $\`{a}$ celui d' architecture. La sculpture et l' architecture $r\'{e}ciproque$ l' espace tridimensionnel entre eux, mais selon l' argument do Herbert Read pour la distinction de ces deux arts originaux sont, deux saisies de l' espace, ici englobant, $l\`{a}$ $englob\'{e}$. On $\'{e}tudie$ dans co set de concept de l' espace et de l' $\'{e}chelle$ d' objet par rapport au corps humain.

• Journal of the Korean Wood Science and Technology
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• 제12권3호
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• pp.25-34
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• 1984

This experiment was carried out to investigate the effects of monosaccharides extracted by saturated portland cement solution on the cement setting in comparision with the inhibitory index (I) of each lignocellulosic-cement system. The wood species which have been widely reforested in Korea, Populus alba-grandulosa, Larix leptolepis, Abies holophylla, Pinus koraiensis, Pinus rigida, Pinus densiflora and agricultural wastes of rice husk and rice stalk were used at this study. The wood meal, 0.50g on dry weight basis, through 0.83 mm(20 mesh) and retained on 0.35mm (40 mesh) screen was extracted by 25 ml saturated portland cement solution and the pH of saturated portland cement solution Was 12.7. To eliminate cation exsisting in the extracted solution, the cation exchange column was used (Fig. 4). Afterwards the extracted monosaccharides were reduced into alditols with sodium borohydride and analyzed by the gas-liquid chromatography for xylan, mannan, arabinan, galactan, gluean. The heat of cement hydration for lignocellulosic-cement system was measured in Dewar flask (Fig. 2). And then the inhibitory indices were calculated from maximum hydration temperature, time and maximum slops of hydration curve of ligno cellulosic-cement systems. The results obtained were as follows; (1) The inhibitory index of pines-Pinus rigida (I=29.33) and Pinus densiflora (I=35.76), were lower than that of poplar-Populus alba-glandulosa (I=41.48), and the index of Larix ieptoiepis (I=73.00) was the highest among eight lignocellulosic-cement systems, and accordingly both Pinus rigida and Pinus des(flora were seemed to be good wood species for wood-cement composite manufacture. (2) In case of Pinus rigida, the inhibitory index was 29.33 and the ratio of the hexoses to the pemoses was 6.04 and in case of Larix leptolepis, the index and the ratio were 73.00 and 35.19, respectively. Therefore the inhibitory index increased with increasing the ratios of the hexoses to the pentoses. (3) The richer amount of xylose and mannose in species caused decreasing the slops of the hydration curve of the lignocellulosic-cement system, prohahly due to the chemical adsorption of the acetyl groups in the hemicellulose on the surface of cement grains. (4) The amoun of xylose and mannose were significant to the inhibitory index of each lignocellulosic-cement system but any specific relation between the amount of glucose and inhibitory index was not found.

• 방송공학회논문지
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• 제17권2호
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• pp.374-387
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• 2012

본 논문에서는 이산 웨이블릿 패킷 변환을 이용하여 디지털 홀로그램의 중요 성분을 추적하고 암호화하는 알고리즘을 위한 하드웨어를 구현하였다. 웨이블릿 변환과 부대역의 패킷화를 이용한 암호화 방법을 이용하고, 적용된 암호화 기법은 웨이블릿 변환의 레벨과 에너지 값을 선택함으로써 다양한 강도로 암호화가 가능하다. 디지털 홀로그램의 암호화는 크게 두 부분으로 구성되는데 첫 번째는 웨이블릿 변환을 수행하는 것이고, 두 번째는 암호화를 수행하는 것이다. 고속의 웨이블릿 변환을 하드웨어로 구현하기 위해서 리프팅 기반의 하드웨어 구조를 제안하고, 다양한 암호화를 수행하기 위해서는 다중모드를 가지는 블록암호시스템의 구조를 제안한다. 동일한 구조의 반복적인 연산을 통해서 수행되는 리프팅의 특성을 이용하여 단위 연산을 수행할 수 있는 셀을 제안하고 이를 확장하여 전체 리프팅 하드웨어를 구성하였다. 블록 암호시스템의 구성을 위해서 AES, SEED, 그리고 3DES의 블록암호화 알고리즘을 사용하였고 데이터를 최소의 대기시간(최소 128클록, 최대 256클록)만을 가지면서 실시간으로 데이터를 암호화 혹은 복호화시킬 수 있다. 디지털 홀로그램은 전체 데이터 중에서 단지 0.032%의 데이터만을 암호화되더라도 객체를 분간할 수 없었다. 또한 구현된 하드웨어는 $0.25{\mu}m$ CMOS 공정에서 약 20만 게이트의 자원을 사용하였고, 타이밍 시뮬레이션 결과에서 살펴볼 때 약 165MHz의 클록속도에서 안정적으로 동작할 수 있었다.

• 대한환경공학회지
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• 제22권11호
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• pp.1985-1994
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• 2000

본 연구는 페놀의 초기 홉착량, 온도, pH가 유기용매에 의한 페놀 탈착에 미치는 영향을 조사하기 위한 것으로 methanol, acetone, N,N-dimethylformamide(DMF)를 유기용매로 사용하였다. 초기 흡착량은 166.1mg/g, 180.7mg/g, 197.9mg/g의 세 경우, 온도는 $15{\sim}55^{\circ}C$까지 $10^{\circ}C$ 간격으로 다섯 온도 조건, pH는 산성, 중성, 염기성에서의 페놀 탈착율 변화를 살펴보았다. 페놀의 탈착은 용매의 극성 모멘트와 비례하여 methanol < acetone < DMF 순으로 나타났으며, acetone과 DMF의 경우에는 탈착율이 약 90% 정도로 유사하였다. 초기 흡착량이 증가할수록 용매에 의한 페놀 탈착율은 직선적으로 감소하였으며, DMF에 의한 탈착율 감소 정도가 가장 완만한 것으로 미루어 초기 흡착량이 DMF 탈착 성능에 미치는 영향이 가장 적은 것으로 나타났다. 온도가 높아질수록 페놀 탈착도 증가하였으며, methanol의 증가폭이 가장 큰 것으로 미루어 methanol에 의한 페놀 탈착반응이 온도에 가장 민감함을 알 수 있다. 용매 pH가 높아질수록 페놀 탈착율도 증가하였으며, 특히 methanol의 경우는 pH 12에서 페놀의 탈착율이 10% 이상 급격히 증가되었으며, 이는 methanol의 탈착 능력이 pH의 영향을 가장 많이 받는 것으로 추정된다. 세 용매 중에서 methanol의 페놀 탈착율이 가장 떨어졌으나, 온도와 pH를 조절하게 된다면 acetone, DMF와 유사한 탈착율을 보였으며, methanol이 가장 저렴하기 때문에 적정한 탈착 조건을 선정 적용한다면 경쟁력있는 재생 용매로서 가능성을 지니고 있다고 판단된다.

• 환경생물
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• 제19권2호
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• pp.159-171
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• 2001

시화호 내해의 저서퇴적물에 서식하는 중형저서생물의 군집구조, 수평분포, 서식 밀도, 선충류/저서성 요각류비 등을 연구하기 위하여 1999년 5월과 2000년 5월에 총 19개의 정점에서 조사를 실시하였다. 중형저서동물은 1999년 총 11개의 분류군, 2000년 8개의 분류군이 출현하여, 다른 연안 해역에 비하여 아주 낮은 분류군이 출현하였다. 두 시기 모두 출현 분류군 중 선충류(nemato-des)가 가장 우점하고 있었고, 그 다음으로 중요한 출현분류군은 유공충류(sarcomastigophorans), 갑각류의 유생(nauplius), 저서성 요각류 (benthic harpacticoids), 갯지렁이류(polychaetes)로 이들 5개의 분류군이 전체 중형동물 출현 개체수의 90% 이상을 차지하고 있었다. 2000년에는 이들 분류군 이외에 갯지렁이의 유생 (poly-chaetes larvae)이 아주 많이 나타나는 특징을 보였다. 개체수 크기는 체 크기 0.063mm에 들어가는 크기의 생물들이 가장 많이 나타났다. 서식 밀도는 시화호 안쪽의 상부 정점들에서 각 시기 모두 아주 낮게 나타났고, 시화호 배수 갑문 근처인 하부 해역에서 높게 나타났으며, 그 중간 해역에서는 서식밀도 역시 중간 값을 보였다. 환경 오염 지수의 하나인 선충류/저서성요각류 비(N/C ratio)역시 시화호 배수 갑문 근처의 정점들에서는 낮게 나타나고, 안쪽의 상부 정점들에서는 아주 높게 나타나, 시화호 저서 퇴적물의 환경은 시화호 하부인 수문이 위치한 해역에서 상부로 갈수록 생물들이 서식하기에 적합하지 않은 현상을 보였으며, 특히 상부 해역은 아주 극심한 오염된 환경을 나타냈다.

• Fisheries and Aquatic Sciences
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• 제22권12호
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• pp.30.1-30.11
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• 2019

Marine natural products isolated from the sponge Fascaplysinopsis cf reticulata, in French Polynesia, were investigated as an alternative to antibiotics to control pathogens in aquaculture. The overuse of antibiotics in aquaculture is largely considered to be an environmental pollution, because it supports the transfer of antibiotic resistance genes within the aquatic environment. One environmentally friendly alternative to antibiotics is the use of quorum sensing inhibitors (QSIs). Quorum sensing (QS) is a regulatory mechanism in bacteria which control virulence factors through the secretion of autoinducers (AIs), such as acyl-homoserine lactone (AHL) in gram-negative bacteria. Vibrio harveyi QS is controlled through three parallel pathways: HAI-1, AI-2, and CAI-1. Bioassay-guided purification of F. cf reticulata extract was conducted on two bacterial species, i.e., Tenacibaculum maritimum and V. harveyi for antibiotic and QS inhibition bioactivities. Toxicity bioassay of fractions was also evaluated on the freshwater fish Poecilia reticulata and the marine fish Acanthurus triostegus. Cyclohexanic and dichloromethane fractions of F. cf reticulata exhibited QS inhibition on V. harveyi and antibiotic bioactivities on V. harveyi and T. maritimum, respectively. Palauolide (1) and fascaplysin (2) were purified as major molecules from the cyclohexanic and dichloromethane fractions, respectively. Palauolide inhibited QS of V. harveyi through HAI-1 QS pathway at 50 ㎍ ml^-1 (26 μM), while fascaplysin affected the bacterial growth of V. harveyi (50 ㎍ ml^-1) and T. maritimum (0.25 ㎍). The toxicity of fascaplysin-enriched fraction (FEF) was evaluated and exhibited a toxic effect against fish at 50 ㎍ ml^-1. This study demonstrated for the first time the QSI potential of palauolide (1). Future research may assess the toxicity of both the cyclohexanic fraction of the sponge and palauolide (1) on fish, to confirm their potential as alternative to antibiotics in fish farming.

• The Korean Journal of Physiology and Pharmacology
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• 제22권2호
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• pp.173-182
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• 2018

Recent studies have provided several lines of evidence that peripheral administration of oxytocin induces analgesia in human and rodents. However, the exact underlying mechanism of analgesia still remains elusive. In the present study, we aimed to identify which receptor could mediate the analgesic effect of intraperitoneal injection of oxytocin and its cellular mechanisms in thermal pain behavior. We found that oxytocin-induced analgesia could be reversed by $d(CH_2)_5[Tyr(Me)^2,Dab^5]$ AVP, a vasopressin-1a (V1a) receptor antagonist, but not by $desGly-NH_2-d(CH_2)_5[D-Tyr^2,Thr^4]OVT$, an oxytocin receptor antagonist. Single cell RT-PCR analysis revealed that V1a receptor, compared to oxytocin, vasopressin-1b and vasopressin-2 receptors, was more profoundly expressed in dorsal root ganglion (DRG) neurons and the expression of V1a receptor was predominant in transient receptor potential vanilloid 1 (TRPV1)-expressing DRG neurons. Fura-2 based calcium imaging experiments showed that capsaicin-induced calcium transient was significantly inhibited by oxytocin and that such inhibition was reversed by V1a receptor antagonist. Additionally, whole cell patch clamp recording demonstrated that oxytocin significantly increased potassium conductance via V1a receptor in DRG neurons. Taken together, our findings suggest that analgesic effects produced by peripheral administration of oxytocin were attributable to the activation of V1a receptor, resulting in reduction of TRPV1 activity and enhancement of potassium conductance in DRG neurons.