• Title/Summary/Keyword: Depth recovery

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Histopathological and Neurobehavioral Characterization in Adult Mice Exposed to Traumatic Brain Injury (C57BL/6 쥐 외상성 뇌손상 모델에서 뇌 손상 정도에 따른 조직병리학적 변화 및 신경행동학적 특징)

  • Oh, Ki Young;Choi, Dong Won;Jang, Moon Soon;Lee, Ji Han;Kim, Sang Chul;Park, Jung Soo;Lee, Suk Woo;Kim, Hoon
    • Journal of The Korean Society of Emergency Medicine
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    • v.28 no.5
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    • pp.457-466
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    • 2017
  • Purpose: Traumatic brain injury (TBI) is a significant cause of morbidity and mortality worldwide. Severity of the initial insult is one of the most significant factors affecting outcome following TBI. In order to investigate the mechanisms of cellular injury and develop novel therapeutic strategies for TBI, we designed a standardized animal TBI model and evaluated histological and functional outcomes according to the degree of impact severity. Methods: Male adult C57Bl/6 mice underwent controlled cortical impact (CCI) at varying depths of deflection (1.0-2.0 mm). We performed hematoxylin and eosin staining at 7 days after recovery from TBI. Neurobehavioral characterization after TBI was analyzed by the Barnes maze test, passive avoidance test, open field test, rotarod test, tail suspension test, and light/dark test. Results: We observed a graded injury response according to the degree of deflection depths tested (diameter, 3 mm; velocity, 3 m/s; and duration, 500 ms) compared to sham controls. In the Barnes maze test, the severe TBI (2 mm depth) group showed reduced spatial memory as compared with the sham and mild TBI (1 mm depth) groups at 7 days after TBI. There was a significant difference in the results of the open field test and light/dark test among the three groups. Conclusion: Our findings demonstrate that the graded injury responses following TBI resulted in differential histopathological and behavioral outcomes in a mouse experimental CCI model. Thus, a model of CCI with histologic/behavioral outcome analysis may offer a reliable and convenient design for preclinical TBI research involving mice.

Exploring the Meaning of Teaching Experience of Middle School Physical Education Teachers (중학교 체육교사의 교직 경험 의미 탐색)

  • Seung-Yong Kim
    • Journal of Industrial Convergence
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    • v.22 no.3
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    • pp.39-49
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    • 2024
  • The purpose of this study was to explore the meaning of the teaching experience of middle school physical education teachers, listening to in-depth statements related to teaching experience based on the physical education teacher's teaching identity, and analyzing the meaningful content and meaning structure found therein. The study participants were four current middle school physical education teachers. The research method used Colaizzi's phenomenological method to analyze the meaning structure through in-depth interviews with research participants, group interviews, additional interviews, and field records. In order to solve the research questions, the interviews were conducted as semi-structured interviews, and the individual interviews were terminated when there were no more duplicate cases or similar phenomena related to teaching experience. As a result of the study, the meaning of experience was constructed based on narrative statements through interviews with research participants, and a collection of 2 items, 6 categories, and 12 themes were extracted by exploring concepts from the constructed meaning. The reasons for going into the teaching profession were categorized into 'motivation' and 'beliefs', and the meaning of teaching experience was categorized into 'mission', 'relationships', 'exhaustion', and 'overcoming'. In conclusion, although the research participants faced numerous difficulties, they experienced challenges and recovery by pursuing the joy and value of sharing within the school community.

Methane Fermentation of Facultative Pond in Pond System for Ecological Treatment and Recycling of Livestock Wastewater (축산폐수 처리 및 재활용을 위한 조건성연못의 메탄발효)

  • Yang, Hong-Mo
    • Korean Journal of Environmental Agriculture
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    • v.19 no.2
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    • pp.171-176
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    • 2000
  • A wastewater treatment pond system was developed for treatment and recycling of dairy cattle excreta of $5\;m^1$ per day. The wastes were diluted by the water used for clearing stalls. The system was composed of three ponds in series. A submerged gas collector for the recovery of methane was installed at the bottom of secondary pond with water depth of 2.4m. This paper deals mainly with performance of methane fermentation of secondary pond which is faclutative one. The average $BOD_5$, SS, TN, and TP concentrations of influent into secondary pond were 49.1, 53.4, 48.6, and 5.3 mg/l, and those of effluent from it were 27.9, 45.7, 30.8, 3.2 mg/l respectively. Methane fermentation of 2.4-meter-deep secondary pond bottom was well established at $16^{\circ}C$ and gas garnered from the collector at that temperature was 80% methane. Literature on methane fermentation of wastewater treatment ponds shows that methane bacteria grow well around $24^{\circ}C$, the rate of daily accumulation and decomposition of sludge is approximately equal at $19^{\circ}C$, and activities of methanogenic bacteria are ceased below $14^{\circ}C$. The good methane fermentation of the pond bottom around $16^{\circ}C$, about $3^{\circ}C$ lower than $19^{\circ}C$, results from temperature stability, anaerobic condition, and neutral pH of the bottom sludge layer. It is recommended that the depth of pond water could be 2.4m. Gas from the collector during active methane fermentation was almost 83% methane, less than 17% nitrogen. Carbon dioxide was less than 1% of the gas, which indicates that carbon dioxide produced in bottom sludges was dissolved in the overlaying water column. Thus a purified methane can be collected and used as energy source. Sludge accumulation on the pond bottom for a nine month period was 1.3cm and annual sludge depth can be estimated to be 1.7cm. Design of additional pond depth of 0.3m can lead to 15 - 20 year sludge removal.

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Implementation of Motion Analysis System based on Inertial Measurement Units for Rehabilitation Purposes (재활훈련을 위한 관성센서 기반 동작 분석 시스템 구현)

  • Kang, S.I.;Cho, J.S.;Lim, D.H.;Lee, J.S.;Kim, I.Y.
    • Journal of rehabilitation welfare engineering & assistive technology
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    • v.7 no.2
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    • pp.47-54
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    • 2013
  • In this paper, we present an inertial sensor-based motion capturing system to measure and analyze whole body movements. This system implements a wireless AHRS(attitude heading reference system) we developed using a combination of rate gyroscope, accelerometer and magnetometer sensor signals. Several AHRS modules mounted on segments of the patient's body provide the quaternions representing the patient segments's orientation in space. We performed 3D motion capture using the quaternion data calculated. And a method is also proposed for calculating three-dimensional inter-segment joint angle which is an important bio-mechanical measure for a variety of applications related to rehabilitation. To evaluate the performance of our AHRS module, the Vicon motion capture system, which offers millimeter resolution of 3D spatial displacements and orientations, is used as a reference. The evaluation resulted in a RMSE of 2.56 degree. The results suggest that our system will provide an in-depth insight into the effectiveness, appropriate level of care, and feedback of the rehabilitation process by performing real-time limbs or gait analysis during the post-stroke recovery process.

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Distribution Characteristics and Cost Estimation of Collection and Treatment of Deposited Marine Debris in Coastal Fisheries around the Southwestern Islands of Korea (서남해 주요 도서 연안 어장 침적쓰레기의 분포 실태 조사 및 수거 처리 비용 추정)

  • Kim, Seondong;Kang, Wonsoo
    • Journal of the Korean Society for Marine Environment & Energy
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    • v.15 no.4
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    • pp.330-336
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    • 2012
  • We surveyed and evaluated quantities and distribution characteristics of debris on the sea floor around active fishing grounds around the islands in the southwest coast of Korea in 2007 where the average depth is below 40m. Proper recovery gears mainly to haul the derelict fishing gears are selected considering the sea bed types of the areas. The collected debris amounts were used to estimate the total amount of the surveyed area. The number of hauls per trial times the amount of the debris was extended to whole sampling area and the weighting factor from the opinion was applied to reach the total amount of marine debris on the floor. The amount of the deposited marine debris around Wangdeung-do area is estimated as about 686 $kg/km^2$, and the cost of the collection and treatment for the deposited marine debris is estimated about 3.9 billion KRW after consideration of the proper size of the working ships, labor, transport and treatment cost.

Case study of the mining-induced stress and fracture network evolution in longwall top coal caving

  • Li, Cong;Xie, Jing;He, Zhiqiang;Deng, Guangdi;Yang, Bengao;Yang, Mingqing
    • Geomechanics and Engineering
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    • v.22 no.2
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    • pp.133-142
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    • 2020
  • The evolution of the mining-induced fracture network formed during longwall top coal caving (LTCC) has a great influence on the gas drainage, roof control, top coal recovery ratio and engineering safety of aquifers. To reveal the evolution of the mining-induced stress and fracture network formed during LTCC, the fracture network in front of the working face was observed by borehole video experiments. A discrete element model was established by the universal discrete element code (UDEC) to explore the local stress distribution. The regression relationship between the fractal dimension of the fracture network and mining stress was established. The results revealed the following: (1) The mining disturbance had the most severe impact on the borehole depth range between approximately 10 m and 25 m. (2) The distribution of fractures was related to the lithology and its integrity. The coal seam was mainly microfractures, which formed a complex fracture network. The hard rock stratum was mainly included longitudinal cracks and separated fissures. (3) Through a numerical simulation, the stress distribution in front of the mining face and the development of the fracturing of the overlying rock were obtained. There was a quadratic relationship between the fractal dimension of the fractures and the mining stress. The results obtained herein will provide a reference for engineering projects under similar geological conditions.

The phenomenological study on the Experience of the Stop-out of Korean Medicine Students (한의대생의 휴학경험에 관한 현상학적 연구)

  • An, Hyo Ja;Shin, Heon Tae
    • Journal of Society of Preventive Korean Medicine
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    • v.20 no.2
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    • pp.39-51
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    • 2016
  • Objectives : This study was to identify the stop-out experiences of Korean Medicine Students(K.M.S.). The stop-out is defined as a withdrawal temporarily from enrollment at a university. Methods : Data was collected through in-depth individual interviews from 2013 to 2016 and analyzed with Colaizzi's phenomenological methodology. The participants were interviewed once or twice, for 30minutes to 50minutes per interview. Results : Ten theme-clusters were identified from 21 themes. These theme-clusters were divided to 4 divisions as when they made the decision for the stop-out, during their stop-out period, when they went back to school and the meaning of their stop-out. 'A difficult situation to continue the study', 'Uncertainty about their decision and anxiety of the future' are 2 theme-clusters for when they made the decision for the stop-out, 'Conflict and anxiety', 'Novel and free time', 'Improving family relationship and finding new relationship' are 3 theme-clusters for during their stop-out period, 'Anxiety for the returning to school', 'New relationship and sense of relief' are 2 theme-clusters for when they went back to school, and 'Making a present for me', 'An opportunity for the emotional growth', 'Recovery of learning will' are 3 theme-clusters for the meaning of their stop-out that they gave to it. Conclusions : The stop - out of K.M.S. began at the hope that they want to take the lead for their lives. And they would find themselves more mature after the experience of their stop-out. This result could be a basic reference for the counselling of the faculty working with K.M.S.

The gob-side entry retaining with the high-water filling material in Xin'an Coal Mine

  • Li, Tan;Chen, Guangbo;Qin, Zhongcheng;Li, Qinghai;Cao, Bin;Liu, Yongle
    • Geomechanics and Engineering
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    • v.22 no.6
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    • pp.541-552
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    • 2020
  • With the increasing tension of current coal resources and the increasing depth of coal mining, the gob-side entry retaining technology has become a preferred coal mining method in underground coal mines. Among them, the technology of the gob-side entry retaining with the high-water filling material can not only improve the recovery rate of coal resources, but also reduce the amount of roadway excavation. In this paper, based on the characteristics of the high-water filling material, the technological process of gob-side entry retaining with the high-water filling material is introduced. The early and late stress states of the filling body formed by the high-water filling materials are analyzed and studied. Taking the 8th floor No.3 working face of Xin'an coal mine as engineering background, the stress and displacement of surrounding rock of roadway with different filling body width are analyzed through the FLAC3D numerical simulation software. As the filling body width increases, the supporting ability of the filling body increases and the deformation of the surrounding rock decreases. According to the theoretical calculation and numerical simulation of the filling body width, the filling body width is finally determined to be 3.5m. Through the field observation, the deformation of the surrounding rock of the roadway is within the reasonable range. It is concluded that the gob-side entry retaining with the high-water filling material can control the deformation of the surrounding rock, which provides a reference for gob-side entry retaining technology with similar geological conditions.

Penetration of Weathered Oil and Dispersed Oil and its Ecological Effects on Tidal Flat - as Infiltration of Dissolved Matter - (유출된 풍화유와 분산유의 조간대 침투 및 생태계 영향 - 용존상 물질의 침투량 변화 -)

  • Cheong, Cheong-Jo
    • Journal of the Korean Society for Marine Environment & Energy
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    • v.8 no.3
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    • pp.134-139
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    • 2005
  • The purpose of this study is to quantify the penetration behavior of spilled weathered oil and dispersed oil and to evaluate the influence of the penetrated oils on seawater infiltration in tidal flat environment. The penetration depths of the spilled oils into the tidal flat sediments were gradually deeper according to increase the stranded oil volume. The penetration depth of stranded oil were abruptly dropped at first falling tide, but were not significantly fluctuated after that. Moreover, hydrocarbon concentration was most high within the upper 2 cm. Seawater infiltration was decreased in proportion to the stranded oil volume. Dispersed oil was easily permitted the seawater infiltration than weathered oil and crude oil. Therefore, quick cleaning actions fur penetrated oil will be required far recovery of seawater infiltration, because the seawater contains oxygen and nutrients required for the survival of benthic organisms in tidal flat.

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The Effects of Drugs, including Alcohol, on Ocular Health and Contact Lens Wear (약물과 알코올이 눈과 콘택트렌즈에 미치는 영향)

  • Kim, Jae-Min
    • Journal of Korean Ophthalmic Optics Society
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    • v.5 no.1
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    • pp.73-81
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    • 2000
  • This review on ocular toxicology concentrates on the effects on ocular health and contact lens wear induced by systemically used drugs, including alcohol. Many systemically administered drugs produce ocular adverse effects. Fortunately, relatively few are capable of causing significant, irreversible visual impairment. The visual symptoms of acute intoxication are as follows : Drop in vision/visual acuity, diplopia, poor dark adaptation, increase in time for glare recovery, early cataract, decreased depth perception, blue-yellow or red-green colour defect and visual hallucinations. Blinking pattern, tear production, and discoloration of contact lenses can be affected by some systemic or local ocular medications. The cornea, conjunctiva, or eyelids may react to some systemic medications and to some preservatives used in contact lens solutions. The hydrogel contact lens act as a drug reservoir that emits the drug over time. I discuss management of contact lens-induced infectious and inflammatory conditions.

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