• Women's Health Nursing
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• v.9 no.4
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• pp.479-488
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• 2003

Purpose: The purpose of this study was to identify the relationship between self reported climacteric symptoms, and depression, and the quality of life in middle aged women. Method: The subjects of this study were 149 women from 40 to 64 years of age. Climacteric symptoms were measured with Neugarton's tool(1965) and depression with Zung's tool. Quality of life was related to self reported climacteric symptoms were education level (F=3.011, p=.035), income measured by Rho's tool(1988). Result: The general characteristic variables significantly level (F=2.670, p=.057), income satisfaction (F=3.413. p=.011), perceived subjective health condition(F=28.623, p=.000). The general characteristic variables significantly related to depression were age(t=-2.476, p=.014), education level (F=4.492, p.013). income satisfaction (F=2.845, p.026), perceived subjective health condition (F = 8.468, p=.000). The general characteristics variables significantly related to quality of life were income level (F= 5.010, p=.000), income satisfaction (F=6.314, p=.000), perceived subjective health condition (F=3.516, p<=.032). menstruation cycles(t=-2.66, p=.023). The relationship between self reported climacteric symptoms and depression had a statistically a positive correlation (r=.357, p=.000). The relationship between depression and quality of life had a statistically with a negative correlation(r=-.397, p=.000). Conclusion: These results may contribute to a better understanding of depression and quality of life in middle aged women. Therefore, health programs for prompting climacteric women´s health should be a planned based on results of the study.

• Tuberculosis and Respiratory Diseases
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• v.82 no.3
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• pp.217-226
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• 2019

Background: Depression is a recognized complication of lung cancer underreported in developing countries such as Malaysia. Treating and identifying depression in cancer patients increases survival and quality of life. Our objectives are to study prevalence of depressive symptoms in newly diagnosed lung carcinoma, and examine the relationship of depressive symptoms with other influencing risk factors. Methods: A 2-year, cross sectional study February 2015-February 2017, was conducted at Hospital Tengku Ampuan Afzan, and Penang General Hospital. One hundred and three patients with newly diagnosed, biopsy confirmed primary lung carcinoma were recruited. Self-rated patient's identification sheet, validated Center for Epidemiologic Studies Depression (CES-D), and Dukes University Religion Index score from three different main languages were used. Results: Prevalence of current depressive symptoms (CES-D total score ${\geq}16$) is 37.9%. The result suggests prevalence of those at high risk of moderate to major depression, may need treatment. Multivariate analysis reveals those with good Eastern Cooperation Oncology Group factor (${\eta}2=0.24$, p<0.001) married (${\eta}2=0.14$, p<0.001) with intrinsic religiosity (IR) (${\eta}2=0.07$, p<0.02) are more resistant to depression. Conclusion: One in three of lung carcinoma patients, are at increased risk for depression. Clinicians should be aware that risk is highest in those with poor performance status, single, and with poor IR. We suggest routine screening of depression symptoms as it is feasible, to be performed during a regular clinic visit with immediate referral to psychiatrist when indicated.

• Journal of Oriental Neuropsychiatry
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• v.20 no.2
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• pp.177-186
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• 2009

Objectives : We investigated if korean traditional treatment and psychotherapy is effective in patients with depression and menopausal symptoms. Methods : We treated two patients with typical korean traditional medical treatment( Acupuncture, Giungoroen therapy(至言高論療法), Moxibustion ) and progressive muscle relaxation. Results : After treatment, the chief complaint and accompanying symptoms were subsided and improved. BDI score and Kupperman's index were decreased. Conclusions : We may conclude that korean traditional treatment and psychotherapy is effective in patients with depression and menopausal symptoms.

• Journal of Korean Academy of Nursing
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• v.37 no.7
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• pp.1131-1138
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• 2007

Purpose: The purpose of this study was to investigate the relationships among depression, somatic symptoms, and activities of daily living of elderly women in urban areas. Method: After obtaining participant's consent forms, a one-time, face-to-face, and private interview was conducted with each participant from Sep, 2006 to Jan, 2007 by trained graduate-level students. The questionnaire consisted of K-GDS, PHQ-15, Barthel Index, and Instrumental Activity of Daily Living. The collected data was analyzed with the SPSS/PC 12.0 program, which was used for frequency, percentage, mean, standard deviation, Pearson correlation coefficients, and multiple regression. Results: The major findings of this study were as follows 1) 34.1% of participants belonged to the depression group. 2) There were significant relationships between depression and monthly income, somatic symptoms, ADL, IADL, and number of chronic disease. 3) Significant factors influencing depression were somatic symptoms, ADL, and monthly income. Conclusion: The results of this study give useful information for designing interventions and program development for appropriate depression management and care for elderly women.

• Journal of Korean Academy of Nursing
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• v.46 no.3
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• pp.420-430
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• 2016

Purpose: The purpose of this study was to test a hypothetical model of chemotherapy-related cognitive impairment (CRCI) and depression in people with gastrointestinal cancer. Methods: A purposive sample of 198 patients undergoing chemotherapy was recruited from November 2014 to July 2015. The instruments were Everyday Cognition (ECog), Hospital Anxiety Depression Scale (HADS), Functional Assessment of Chronic Illness Therapy-Fatigue (FACIT-F), and M. D. Anderson Symptom Inventory-Gastrointestinal Cancer Module. Data were analyzed using descriptive statistics, correlation, and path analysis. Results: CRCI was directly affected by cancer symptoms (${\beta}=.19$, p=.004) and fatigue (${\beta}=.56$, p<.001)($R^2=47.2%$). Depression was directly affected by fatigue (${\beta}=.48$, p<.001) and CRCI (${\beta}=.27$, p<.001). However, The impact of cancer symptoms on depression was confirmed through the mediating effect of CRCI. Conclusion: Results indicate that in patients with gastrointestinal cancer undergoing chemotherapy along with the direct physiologic effects (fatigue, symptoms) of cancer treatment may have altered cognitive function leading to depression.

• Journal of Preventive Medicine and Public Health
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• v.49 no.3
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• pp.176-182
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• 2016

Objectives: Prospective evaluations of the associations between depressive symptoms and suicide deaths have been mainly performed in high-risk populations, such as individuals with psychiatric disorders or histories of self-harm. The purpose of this study was to prospectively examine whether more severe depressive symptoms assessed using the Geriatric Depression Scale (GDS) were associated with a greater risk of death from suicide in a general-risk population. Methods: A total of 113 478 men from the Korean Veterans Health Study (mean age, 58.9 years) who participated in a postal survey in 2004 were followed up for suicide mortality until 2010. Results: Over 6.4 years of follow-up, 400 men died by suicide (56.7 deaths per 100 000 person-years). More severe depressive symptoms were associated with greater risk of suicide death (p for trend <0.001). The unadjusted hazard ratios (HRs) in comparison to the absence of depression were 2.18 for mild depression, 2.13 for moderate depression, 3.33 for severe depression, and 3.67 for extreme depression. After adjusting for potential confounders, men with a potential depressive disorder had an approximate 90% higher mortality from suicide (adjusted HR, 1.92; 95% confidence interval [CI], 1.38 to 2.68; p<0.001) than men without depression. Each five-point increase in the GDS score was associated with a higher risk of death by suicide (adjusted HR, 1.22; p<0.001). The value of the area under the receiver operating characteristics curve of GDS scores for suicide deaths was 0.61 (95% CI, 0.58 to 0.64). Conclusions: Depressive symptoms assessed using the GDS were found to be a strong independent predictor of future suicide. However, the estimate of relative risk was weaker than would be expected based on retrospective psychological autopsy studies.

• Journal of Korean Academy of Nursing
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• v.29 no.2
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• pp.225-237
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• 1999

The purpose of this study was to analyze the relationship among the health promoting behaviors, self-reported climacteric symptoms and depression on a cross-sectional survey desist The subjects were 108 middle-aged women who were nonhystrectomized and ranged in age from 40 to 60. They were selected in Seoul and Kyoung-ki province. Korea. Data were collected from Oct. 25 to Nov. 10, 1997 by a structured Questionnaire. The instrument used for this study was the revised Health Promotion Lifestyle Profile(HPLP) developed by Walker, Sechrist and Pender, revised Climacteric Symptoms Scale developed by Chi, Sung Ai, and the Beck's Depression Inventory(BID). The data were analyzed by the SPSS /PC$^{＋}$ program using t-test, ANOVA and Scheffe test as a post hoc and Pearson Correlation Coefficient. The results of the study were as follows ; 1. The mean score of health promoting behaviors was low(2.42$\pm$0.35). There were statistically significant difference in the score of health promoting behaviors according to the educational background. family income, marital satisfaction, and whether or not taking a restoraitve food(t ＝－2.07, F＝2.60~7.57, p＜0.05). 2. The mean score of self-reported climacteric symptoms was 1.69 ; 99% of middle-aged women had symptoms. There were statistically significant difference in the score of middle-aged women's self-reported climacteric symptoms according to the age, number of children, educational background, occupation, family income, marital satisfaction, whether or not receiving hormone replacement therapy(HRT) or consultation experience with a professional, and perceived health status(t＝－2.04~3.69. F＝2.87~11.63, p＜0.05). 3. The mean score of depression was 10.84. There were statistically significant differences in the score of the depression according to the age, number of children, educational background, occupation, marital satisfaction, whether or not receiving menopausal treatment or consultation by a professional, and perceived health status(t ＝－2.25~3.00, F＝3.50~9.24, p＜0.05). 4. Women's degree of health promoting behaviors was a negative correlation with the degree of climacteric symptoms(r＝－0.19, p＝0.03) and the degree of depression(r＝－0.23, p＝0.01). The degree of climacteric stmptoms was a positive correlation with the degree of depression(r＝0.64 p＝0.01). In conclusion. health promoting behavior should be considered when developing nursing strategies for middle-aged women. especially when dealing with climacteric symptoms and depression.

• Women's Health Nursing
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• v.26 no.3
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• pp.231-239
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• 2020

Purpose: The purpose of this study was to investigate factors affecting premenstrual symptoms among nursing students, focusing on depression, fatigue, and body esteem. Methods: The participants were 145 nursing students at a university located in Changwon, Korea. Data were collected from November 2 to November 30, 2019 using self-reported structured questionnaires, and analyzed using descriptive statistics, independent t-test, analysis of variance, Pearson correlation coefficients, and multiple regression analysis. Results: The mean item score for premenstrual symptoms was 2.52±0.92, indicating a low level. The mean score for depression was 16.05±7.72, and 15.2% of participants were found to be moderately depressed and 9.7% severely depressed. The mean item score for fatigue was 4.84±0.84, indicating a moderate level, and body esteem was 2.94±0.44, indicating a moderate level. The premenstrual symptoms of nursing students showed a statistically significant correlation with depression (r=-.58, p<.001), fatigue (r=.33, p<.001), and body esteem (r=-.28, p<.001). Factors impacting premenstrual symptoms of nursing students were depression (β=.47, p<.001), dysmenorrhea (β=-.18, p=.009), menstrual cycle irregularity (β=.17, p=.013), and body esteem (β=-.14, p=.038). The total explanatory power of these variables was 41.0%. Conclusion: Findings from this sample of nursing students suggest that intervention programs to relieve premenstrual symptoms should focus on depression, menstrual cycle irregularity, dysmenorrhea, and body esteem.

• Korean Journal of Biological Psychiatry
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• v.17 no.2
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• pp.86-93
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• 2010

Objectives : The aim of this research is to determine the effects of depression and anxiety symptoms of schizophrenic psychopathology on the HPA axis. Methods : Twenty patients with schizophrenia were included and divided into the medication non-exposed group(n = 10) and the medication exposed group(n = 10). Evaluated scales were the Positive and Negative Syndrome Scale(PANSS), Scale for the Assessment of Negative Symptoms(SANS), Scale for the Assessment of Positive Symptoms(SAPS), Hamilton Depression Inventory(HAM-D) and Hamilton Anxiety Inventory (HAM-A), and then the combined Dexamethasone/Corticotropin Releasing Hormone(DEX/CRH) test was conducted to determine the basal level, the peak level and the area under the curve(AUC) of cortisol and adrenocorticotropic hormone(ACTH). Results : When the correlations between each psychopathology and cortisol level or ACTH AUC value were analyzed, HAM-D showed a negative correlation, whereas HAM-A showed a positive correlation. Also, the non-depression group(HAM-D ${\leq}$ 18) showed higher cortisol and ACTH concentrations than the depression group(HAM-D > 18), and the anxiety group(HAM-A ${\geq}$ 14) showed significantly higher concentrations than the non-anxiety group(HAM-D < 14)(p < 0.05). Also, as for the comparison between the medication non-exposed group and the medication exposed group, the non-exposed group showed significantly higher cortisol and ACTH concentration than exposed group(p < 0.05). Conclusion : This study suggest that anxiety symptoms rather than depression symptoms are related to the increased activity of the HPA axis of schizophrenics.

• Korean Journal of Clinical Pharmacy
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• v.34 no.2
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• pp.118-125
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• 2024

Background: Numerous studies have consistently demonstrated that depression can be associated with cognitive function decline, primarily focusing on older adults due to the neurodegenerative characteristics of dementia. With persistent depression frequently reported in patients with early-onset or young-onset dementia, this study aimed to assess the impact of depression, specifically the changes in depressive symptoms over time, on the risk of cognitive function decline in middle-aged adults in Korea. Methods: This retrospective study utilized data from the first four waves (2006-2012) of the Korean Longitudinal Study of Aging (KLoSA), focusing on middle-aged adults with normal cognitive function at baseline. Changes in depressive symptoms were categorized into four groups based on the CES-D score, and their association with cognitive function decline was evaluated using a multivariate logistic regression model. Results: Of the initial 10,254 participants, 3,400 were included in the analysis. Depressive status, particularly newly onset (adjusted odds ratio [aOR] 1.96; 95% confidence interval [CI] 1.32-2.93) and persistent depression groups (aOR 5.59; 95% CI 2.90-10.78), were significantly associated with cognitive function decline. In contrast, recovery from depressive symptoms was not significantly associated with cognitive function decline (p=0.809). Conclusions: Our study showed a significant association between changes in depressive symptoms and cognitive function decline in middle-aged Korean adults. This suggests that management of depressive symptoms could be crucial for the prevention of cognitive function decline in this population.