• Nutrition Research and Practice
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• 제15권4호
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• pp.468-478
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• 2021

BACKGROUND/OBJECTIVES: This study aimed to analyze the association between dietary omega-3 fatty acid intake and depression in postmenopausal women using data from the Korea National Health and Nutrition Examination Survey (KNHANES) VI. SUBJECTS/METHODS: The KNHANES is a cross-sectional nationwide health and nutrition survey. Dietary data, including omega-3 fatty acids, were assessed using the 24-h recall method. Depression was evaluated using a survey questionnaire. The association between dietary omega-3 fatty acids and depression was evaluated using multivariate logistic regression analysis. Depression, according to the dietary omega-3 fatty acid intake, was expressed as the odds ratio (OR) with a 95% confidence interval (CI). A total of 4,150 postmenopausal women were included in the analysis. RESULTS: In the fully-adjusted model, the group with the highest dietary omega-3 fatty acid intake significantly showed lower prevalence of depression than the group with the lowest intake (OR, 0.52; 95% CI, 0.33-0.83); a significant linear trend was detected (P for trend = 0.04). According to the dose-response analysis using cubic restricted spline regression, this association was linear and monotonic (P for non-linearity = 0.32). CONCLUSIONS: In this study, the dietary omega-3 fatty acid intake in postmenopausal women was inversely proportional to depression in a dose-response manner. Large cohort studies are needed to verify the causality between omega-3 fatty acids and depression in Korean postmenopausal women.

• Journal of Korean Biological Nursing Science
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• 제11권1호
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• pp.23-31
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• 2009

Purpose: The purpose of the present study was to investigate the prevalence and related factors of sleep-wake disturbance (SWD) in Korean post-stroke patients. This study was the first to address post-stroke SWD in Korea using a structured questionnaire. Method: We investigated the prevalence of SWD and related factors including lesion location, stroke severity, presence of depression and fatigue. We assessed sleep-wake pattern including quality of sleep, sleep latency, wake episodes, wake time after sleep onset, daytime sleep episode and sleep time at daytime. Ninety stroke patients admitted to a university affiliated hospital in Seoul between the period September 2008 and January 2009 were included in the study. Result: Thirty five patients (38.9%) complained insomnia and 32 (35.6%) complained excessive daytime sleepiness (EDS). Quality of sleep (p=.000), sleep latency (p=.000) and total sleep time (p=.001) were significantly poorer in 16 patients with both insomnia and EDS than in the others. The related factors to insomnia were level of education (p=.030), depression (p=.007) and fatigue (p=.034), though related factors to EDS were stroke onset time (p=.049), stroke severity (p=.005), motor dysfunction (p=.035), dysphasia (p=.018), fatigue (p=.001) and lesion location (p=.019). Conclusion: Sleep-wake disturbance is a common problem in Korean stroke patients. Strategies to improve quality of sleep are urgently needed in the post-stroke patients.

• 대한약침학회지
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• 제27권3호
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• pp.253-263
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• 2024

Objectives: Nurses face mental health issues like emotional labor, stress, and depression, increasing the risk of medical errors. This study assesses the mental health and medical errors among nurses in Korean medicine clinics in South Korea. Methods: The cross-sectional analysis involved 83 nurses, examining relationships between emotional labor, stress, depression, cognitive failure, Hwa-byung (HB) (a syndrome of suppressed anger in Korean culture), and medical errors. It identified factors associated with HB and medical errors using multiple regression analysis, presenting their odds ratios (ORs) with 95% confidence intervals (CIs). Results: The findings revealed a current HB prevalence of 19.28% and a 6-month medical error prevalence of 16.87% among participants. The regression analysis showed that higher levels of depression (OR = 1.368, 95% CI = 1.098 to 1.703, p = 0.005), cognitive failure (OR = 1.072, 95% CI = 1.011 to 1.136, p = 0.020), and HB trait (OR = 1.136, 95% CI = 1.005 to 1.284, p = 0.041) significantly correlated with HB presence. Conclusion: This groundbreaking study on this previously under-researched nurse workforce highlights the critical need for comprehensive mental health care, with the objective of significantly enhancing their mental well-being and improving their overall work environment.

• Asian Pacific Journal of Cancer Prevention
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• 제16권3호
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• pp.1251-1254
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• 2015

Background: To compare prevalence of anxiety in ovarian cancer patients following primary treatment to that of normal women and to examine predicting factor. Materials and Methods: In this cross-sectional study, 56 ovarian cancer patients who had primary surgical treatment within the past five years (cancer group) and 56 age-matched women who attended an outpatient clinic for check-ups (non-cancer group) were recruited from June 2013 to January 2014. The hospital anxiety and depression scale (HADS), was used to determine anxiety level of the participants with the score of ${\geq}11$ suggestive of anxiety. The prevalence of anxiety symptoms and mean HADS scores for anxiety were compared between the study groups. For those with ovarian cancer, associations of demographic and clinical factors with anxiety was examined. A p-value of <0.05 was considered significant. Results: Participants in the non-cancer group had higher rate of medical comorbidity, higher salary, and more frequent university education. The prevalence of anxiety was not different between the groups, at 7.1% each. The mean HADS scores for anxiety subscale were not significantly different between the groups, 5.0 in the cancer group vs 6.1 in the non-cancer group (p=0.09). On multivariable analysis, no demographic or clinical factors significantly associated with anxiety were identified. For the cancer group, no association between any particular factors and anxiety was demonstrated. Conclusions: The prevalence of anxiety in women with ovarian cancer following primary treatment was comparable to that of normal women seeking routine check-up.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제22권6호
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• pp.527-535
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• 2019

Purpose: There is increasing prevalence of psychiatric disorders among inflammatory bowel Disease (IBD) population. Further, presence of psychiatric disorders has been shown as an independent predictor of quality of life among patients with IBD. We intended to explore the prevalence of various psychiatric disorders among pediatric and young adult population with IBD as a population-based analysis. Methods: We did a retrospective case control analysis using a deidentified cloud-based database including health care data across 26 health care networks comprising of more than 360 hospitals across USA. Data collected across different hospitals were classified and stored according to Systematized Nomenclature of Medicine-Clinical Terms. We preidentified 10 psychiatric disorders and the queried the database for the presence of at least one of the ten psychiatric disorders among IBD patients between 5 and 24 years of age and compared with controls. Results: Total of 11,316,450 patients in the age group between 5 and 24 years and the number of patients with a diagnosis of IBD, Crohn's disease or ulcerative colitis were 58,020. The prevalence of psychiatric disorders was 21.6% among IBD mainly comprising of depression and anxiety disorder. Multiple logistic regression analysis showed, IBD is 5 times more likely associated with psychiatric disorders than controls, p<0.001). We showed a steady increasing trend in the incidence of psychiatric disorders among IBD patients (2% in 2006 to 15% in 2017). Conclusion: Largest population-based analysis demonstrated an increased prevalence of psychiatric disorders among IBD patients. Our study emphasizes the need for psychological and mental health services to be incorporated as a part of the routine IBD clinic.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• 제23권3호
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• pp.134-142
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• 2012

Objectives : Childhood depressive disorder one of the most prevalent chronic health conditions affecting school aged children. The objective of this study was to examine the prevalence and epidemiological characteristics of childhood depressive disorder in Korea. Methods : In this study, a survey was conducted of elementary school children in the Cheonan area from September 2009 to August 2010. A total of 12,084 children were included in the analyses. The primary measure of depression was the 27-item Kovacs' Children's Depression Inventory (CDI), the Korean Dupaul attention-deficit hyperactivity disorder Rating Scales (K-ARS), Autism Spectrum Screening Questionnaire (ASSQ) and Restless Legs Syndrome Questionnaire (RLSQ) were also administered. Results : The prevalence rate of childhood depressive disorder was 3.07%. The mean age was $9.21{\pm}1.81$ years for the control group (5,969 male, 6,054 female) and $9.91{\pm}1.83$ years for the depression group (CDI score${\geq}$22 ; 159 male, 210 female). Age, height, weight, and economic status were similar for the two groups. However, there were statistically significant differences in the distribution of sex. The distribution of school grade also differed between the two groups. Scores for CDI, K-ARS, and ASSQ in the depressive group were higher than those of the control group. Conclusions : This is the first large-scale population-based study to report on the prevalence of childhood depressive disorder in South Korea. Increased rates of childhood depressive disorder, as reported by primary caretakers, might reflect the increasing negative impact of environmental risk factors on neurobehavioral health. Longitudinal study of the prevalence of childhood depressive disorder should be considered for further evaluation.

• 구강회복응용과학지
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• 제36권1호
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• pp.12-20
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• 2020

목적: 본 연구는 일반 인구의 대표 표본에서 우울증의 발현과 심각도, 씹기 불편감 사이의 관계를 분석하였다. 연구 재료 및 방법: 전국 대표 표본(n = 8150)을 대상으로 하였으며, 씹기 불편감은 해당 문제에 관한 설문 조사에 응답한 사람들로 정의하였다. 우울증은 PHQ-9 설문 조사에서 총 점수가 10점 이상인 대상자로 정의하였다. 인구 통계, 사회적 경제적 특성 및 동반 질환에 관한 데이터를 포함하여 다중 로지스틱 회귀 분석을 수행하고 분석하였다. 결과: 한국인의 경우 씹기 불편감이 없는 사람(10.2%)보다 씹기 불편감이 있는 사람(17.2%)에서 우울증의 유병률이 유의하게 더 높았다. 다변량 로지스틱 회귀 분석에서 우울증의 존재는 CP와 유의하게 관련 있었다(adjusted odd ratio [aOR]: 1.90, P < 0.001). 씹기 불편감의 위험은 우울증의 심각도가 증가함에 따라 증가하였다: 중증 우울증(OR: 2.62, P < 0.001), 중등도 우울증(OR: 2.19, P < 0.001). 결론: 중증 우울증을 보이는 개인에서 우울증의 공존여부가 씹기 불편감과 상당히 연관되었다. 씹기 불편감 환자 치료에 있어 우울증의 선별검사가 고려되어야 한다.

• 한국식품영양과학회지
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• 제43권10호
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• pp.1467-1476
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• 2014

본 연구에서는 비타민 D와 정신질환, 특히 전 세계적으로 높은 유병률 추이를 보이고 있는 우울증과의 연관성을 살펴보기 위해 비타민 D의 종류, 급원 식품, 비타민 D 영양상태 현황 및 이에 영향을 미치는 요인, 비타민 D와 우울증과의 연관성에 대한 국내외 문헌을 체계적으로 고찰하여 요약하였다. 그 결과 첫째, 비타민 D는 자연계에 주로 비타민 $D_2$(ergocalciferol)와 $D_3$(cholecalciferol) 두 가지 형태로 존재하며 주로 대구간유, 고등어, 정어리와 같은 지방이 많은 생선, 난황, 표고버섯 등이 주요 급원 식품이다. 둘째, 국내 외 다양한 인구 집단을 대상으로 비타민 D 수준을 고찰한 결과 비타민 D 결핍은 매우 높은 수준을 보이고 있다. 특히 한국인의 청소년을 대상으로 한 연구 결과 혈청 25(OH)D 20 ng/mL 미만인 남녀는 각각 89%, 99%로 매우 낮은 비타민 D 수준을 보였다. 셋째, 체내 비타민 D의 수준에 영향을 미칠 수 있는 요인으로는 인종, 거주 지역, 위도, 의복차림, 계절적 차이, 직업, 자외선 노출 정도, 보충제 복용 여부 등이 보고되었으며, 일반적으로 연령의 증가(한국인 및 일본인의 경우 반대 방향), 자외선 차단제의 사용, 어두운 피부색, 흡수 불량 및 비만은 비타민 D의 합성, 흡수 및 이용률에 영향을 주어 비타민 D 부족증의 원인이 될 수 있다고 보고되었다. 넷째, 최근 비타민 D 수준과 우울증과의 연관성을 분석한 국외 역학연구들은 꾸준히 보고되고 있으며 이에 대한 횡단 연구와 코호트 연구 결과는 불일치한 양상을 보이고 있다. 또한 최근 비타민 D 보충과의 관계를 규명하기 위해 임상시험연구도 일부 진행되었으나 이 또한 불일치한 결과를 보였지만 보충제로 얻는 비타민 D는 식이로부터 얻는 비타민 D와 다르다는 가능성을 제시하고 있다. 더 나아가 횡단 연구 및 코호트 연구를 메타 분석한 연구 결과 우울증에 대한 비타민 D의 이로운 효과에 대하여 비교적 일치하는 연구 결과를 제시하고 있다. 그러나 대부분의 연구 결과는 국외에서 진행된 연구이며 한국인을 대상으로 분석된 연구는 매우 제한적이다. 따라서 한국인을 대상으로 한 후속 연구가 요구된다.

• 근관절건강학회지
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• 제27권2호
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• pp.189-198
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• 2020

Purpose: The prevalence rate of stroke is increasing due to the rise in the aging population. The stroke sequela, including physical and mental disabilities, remain even though patients are alive, and these circumstances are causing major problems, both socially and economically. This correlation study aimed to identify uncertainty, depression, and quality of life among stroke patients. Methods: Participants included 94 outpatients who were diagnosed with stroke and discharged from a tertiary hospital in S city. Between September and October 2014, a survey on uncertainty, depression, and quality of life was conducted. Data collected were analyzed using SPSS 22.0. Results: The average scores of uncertainty, depression, and quality of life were 48.36 out of 80, 41.90 out of 80, and 175.94 out of 245, respectively. The uncertainties exhibited a positive correlation with depression and a negative correlation with quality of life. The correlation between depression and quality of life was found to be negative. Conclusion: To enhance the quality of life of stroke patients, interventions to reduce uncertainty and depression as well as improve physical care to reduce difficulties in daily living should be implemented.

• 여성건강간호학회지
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• 제12권4호
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• pp.355-362
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• 2006

Purpose: This study was to investigate the degree of postpartum depression and its predictors at six months postpartum. Methods: The subjects were 161 women six months after delivery who were registered with the public health center. The instruments included a survey of various characteristics, the Edinburgh Postnatal Depression Scale(EPDS), husband support, maternal self-esteem, and marital adjustment scale. The data was analyzed using the $x^2$-test, t-test, the Pearson correlation coefficients, and the logistic regression. Results: The point prevalence of postpartum depression at six months postpartum was 14.3%, corresponding to a score of 12 or higher on the EPDS. Postpartum depression was significantly associated with husband support, maternal self-esteem, and marital adjustment. Predictors of postpartum depression identified by the logistic regression analysis include marital adjustment (OR .29 [95% CI .13-.61]) and the delivery method(OR 3.57 [95% CI 1.25-10.23]). Conclusion: Strategies for improving postpartum depression, considerations of husband support and maternal self-esteem are important in research and practice. In addition, interventions for reducing Cesarean delivery and improving marital adjustment are needed.