• IEIE Transactions on Smart Processing and Computing
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• v.4 no.5
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• pp.305-310
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• 2015

We propose a new concept for a depth of interaction (DOI) positron emission tomography (PET) detector based on dual-ended-scintillator (DES) readout for small animal imaging. The detector consists of lutetium yttrium orthosilicate (LYSO) arrays coupled with orthogonal wavelength-shifting (WLS) fibre placed on the top and bottom of the arrays. On every other line, crystals that are 2 mm shorter are arranged to create grooves. WLS fibre is inserted into these grooves. This paper describes the design and performance evaluation of this PET detector using Monte Carlo simulations. To investigate sensitivity by crystal size, five types of PET detectors were simulated. Because the proposed detector is composed of crystals with three different lengths, degradation in sensitivity across the field of view was also explored by simulation. In addition, the effect of DOI resolution on image quality was demonstrated. The simulation results proved that the devised PET detector with excellent DOI resolution is helpful for reducing the channels of sensors/electronics and minimizing gamma ray attenuation and scattering while maintaining good detector performance.

• Environmental Mutagens and Carcinogens
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• v.25 no.2
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• pp.76-81
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• 2005

25-Hydroxycholesterol (cholest-5-ene-3, 25-diol, 25-OHC) showed the cytotoxicity on HeLa human cervix and NCI-H460 human lung cancer cells, $0.5{\mu}M\;of\;50\%$ inhibitory concentration. We studied 25-OHC as the possibility of radiation sensitizer. The combination effect of 25-OHC and y-irradiation measured using flow cytometer with propidium iodide stained cells. The combined treatment of 25-OHC and $\gamma-irradiation$ did not show significant enhancing effects on Hela and NCI-H460 cells.

• Environmental Mutagens and Carcinogens
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• v.25 no.3
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• pp.104-109
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• 2005

[ $7{\beta}$ ]-Hydroxycholesterol (cholest-5-ene-3, 7-diol, $7{\beta}$-OHC) showed the cytotoxicity on human cervical carcinoma cells (HeLa), $10{\mu}M$ of 50% inhibitory concentration. We evaluated $7{\beta}$-OHC as the possibility of radiation sensitizer. The combination effect of $7{\beta}-OHC\;and\;{\gamma}$-irradiation was measured using colony forming assay and flow cytometer with propidium iodide and $DiOC_6$ stained cells, respectively. The combined treatment of $7{\beta}-OHC\;and\;{\gamma}$-irradiation did not show significant enhancing effects on HeLa cells.

• Journal of Magnetics
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• v.21 no.4
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• pp.593-598
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• 2016

In order to reduce the amount of noise component in X-ray imaging system, various reduction techniques were frequently used in the field of diagnostic imaging. Although the previous techniques -such as median, Wiener filters and Anscombe noise reduction technique - were able to reduce the noise, the edge information was still damaged. In order to cope with this problem, total variation (TV) noise reduction technique has been developed and researched. The purpose of this study was to evaluate and compare the image quality using normalized noise power spectrum (NNPS) and contrast-to-noise ratio (CNR) through simulations and experiments with respect to the above-mentioned noise reduction techniques. As a result, not only lowest NNPS value but also highest CNR values were acquired using a TV noise reduction technique. In conclusion, the results demonstrated that TV noise reduction technique is proved as the most practical method to ensure accurate denoising in X-ray imaging system.

• Journal of radiological science and technology
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• v.28 no.2
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• pp.129-135
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• 2005

IT communication industries of current society are developed in enormous growth, our country leading the world in the number of super high speed internet equipments in use. In the pride oneself on communication network of those, mobile terminal technology and wireless phone production hold a high rank. Data communication and networking may be the fastest growing technologies in our culture today. In this way, IT fields conjugated in the daily quick, the fact that department of radiological science didn't discharged one's duties on current IT education. The curriculum of radiological technologists that play an important part between skill and occupation's education as major and personality didn't performed one's part most effectively on current IT environments and digital radiological equipments interface. Therefore, in this paper current curriculum of radiological science are catched hold of trend and problems on digital radiology environments, on fact the present state of problems, for radiological engineering and HIS manager, new curriculum course are suggested a reform measure of culture and major education curriculum introduction.

• Applied Microscopy
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• v.38 no.3
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• pp.235-243
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• 2008

A compact soft x-ray microscope operated in the 'water window' wavelength region ($2.3{\sim}4.4nm$) was used for observing cells with nano-scale spatial resolution. To obtain cellular imaging captured with colloidal gold nanoparticles using a compact soft x-ray microscope. The colloidal gold nanoparticles showed higher contrast and lower transmission more than 7 times than that of cellular protein on the soft x-ray wavelength region. The structure and thickness of the cell membrane of the Coscinodiscus oculoides (diatome) and red blood cells were seen clearly. The gold nanoparticles within the HT1080 and MDA-MB 231 cells were seen clearly on the soft x-ray microscopy. The gold nanoparticles were aggregated within vesicles by endocytosis.

• Proceedings of the Korean Society for Applied Microbiology Conference
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• 2005.06a
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• pp.341-341
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• 2005

• Journal of radiological science and technology
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• v.29 no.4
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• pp.293-301
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• 2006

Currently, Educational program of radiological science is developed in enormous growth, our educational environments leading allied health science education program in the number of super high speed medical industry. Radiological science may be the fastest growing technologies in our medical department today. In this way, Medical industry fields converged in the daily quick, the fact that department of radiological science didn't discharged ones duties on current educational environments. The curriculum of radiological technologists that play an important part between skill and occupation's education as major and personality didn't performed one's part most effectively on current medical environments and digital radiological equipments interface. We expect improvement and suggestion to grow natural disposition as studies in the graduate of radiological science. Therefore, in this paper, current curriculum of radiological science are catched hold of trend and problems on digital radiology environments, on fact the present state of problems, for Graduate program of radiological science, graduate courses of MS and Ph.D. are suggested a reform measure of major education curriculum introduction.

• Journal of radiological science and technology
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• v.28 no.1
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• pp.45-53
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• 2005

This study is aimed at analyzing the relationship between personal factors of radiological technologists and their job stressors. For this aim, a survey was conducted by means of 890 questionnaires from the middle of July to the end of August 2003 to the subjects of radiological technologists who are working for 44 general hospitals in 16 cities and provinces across the country. The results of the survey could be summed up as follows: 1. The biggest stressor that affects a radiological technologist personally under the working situation turned out to be position, job satisfaction and physical symptom(p<0.001), while job satisfaction and physical symptom also played an important role in personal relationship(p<0.001). 2. In terms of job conflicts, colleagues, immediate seniors, job satisfaction and physical symptoms appeared to exercise great impact(p<0.001), As for job autonomy, age, position and job satisfaction were known to be heavily influential(p<0.001). 3. With regard to job load, job satisfaction and behavioral symptom turned out to have great influence while, in job stability, position and job satisfaction seemed to be immensely influential(p<0.001). The present study has a limit in that it covers only radiological technologists who are working at the 3rd reference hospitals but excludes those who are working at the first and second reference hospitals. The findings, however, are surely believed to be able to serve as basic data to improve the medical service quality as they will help reduce the stressors of and enhance mental and physical health for radiological technologists who play important roles as teammates with expertise in the medical field. These outcomes could also be referred to in future studies in this area.

• Journal of the Korean Society of Radiology
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• v.13 no.3
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• pp.415-424
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• 2019

The purpose of this study would like to investigate the effect of major satisfaction on the career decision commitment for students in department of radiological science. Using the structured questionnaire we perform the self-report survey for 218 students. As a result, the degree of major satisfaction for students is found to be mid-range, and the degree of career decision commitment for ones is lowest in the first graders and the highest in the fourth graders. A notable point is that the degree of major satisfaction seems to have a significant influence on career decision commitment. Especially, it was found that major of pride is the most influential factor in career decision commitment. From this study, finally, it seems that a method to improve the career decision commitment is needed because the degree of career decision commitment of students is assessed to be fairly lowered at a level of non-commitment.