• Title/Summary/Keyword: Department of Radiological Science

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Cardiac CT for Measurement of Right Ventricular Volume and Function in Comparison with Cardiac MRI: A Meta-Analysis

  • Jin Young Kim;Young Joo Suh;Kyunghwa Han;Young Jin Kim;Byoung Wook Choi
    • Korean Journal of Radiology
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    • v.21 no.4
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    • pp.450-461
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    • 2020
  • Objective: We performed a meta-analysis to evaluate the agreement of cardiac computed tomography (CT) with cardiac magnetic resonance imaging (CMRI) in the assessment of right ventricle (RV) volume and functional parameters. Materials and Methods: PubMed, EMBASE, and Cochrane library were systematically searched for studies that compared CT with CMRI as the reference standard for measurement of the following RV parameters: end-diastolic volume (EDV), end-systolic volume (ESV), stroke volume (SV), or ejection fraction (EF). Meta-analytic methods were utilized to determine the pooled weighted bias, limits of agreement (LOA), and correlation coefficient (r) between CT and CMRI. Heterogeneity was also assessed. Subgroup analyses were performed based on the probable factors affecting measurement of RV volume: CT contrast protocol, number of CT slices, CT reconstruction interval, CT volumetry, and segmentation methods. Results: A total of 766 patients from 20 studies were included. Pooled bias and LOA were 3.1 mL (-5.7 to 11.8 mL), 3.6 mL (-4.0 to 11.2 mL), -0.4 mL (5.7 to 5.0 mL), and -1.8% (-5.7 to 2.2%) for EDV, ESV, SV, and EF, respectively. Pooled correlation coefficients were very strong for the RV parameters (r = 0.87-0.93). Heterogeneity was observed in the studies (I2 > 50%, p < 0.1). In the subgroup analysis, an RV-dedicated contrast protocol, ≥ 64 CT slices, CT volumetry with the Simpson's method, and inclusion of the papillary muscle and trabeculation had a lower pooled bias and narrower LOA. Conclusion: Cardiac CT accurately measures RV volume and function, with an acceptable range of bias and LOA and strong correlation with CMRI findings. The RV-dedicated CT contrast protocol, ≥ 64 CT slices, and use of the same CT volumetry method as CMRI can improve agreement with CMRI.

Enzymatic properties of the N- and C-terminal halves of human hexokinase II

  • Ahn, Keun-Jae;Kim, Jong-Sun;Yun, Mi-Jin;Park, Jeon-Han;Lee, Jong-Doo
    • BMB Reports
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    • v.42 no.6
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    • pp.350-355
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    • 2009
  • Although previous studies on hexokinase (HK) II indicate both the N- and C-terminal halves are catalytically active, we show in this study the N-terminal half is significantly more catalytic than the C-terminal half in addition to having a significantly higher $K_m$ for ATP and Glu. Furthermore, truncated forms of intact HK II lacking its first N-terminal 18 amino acids ($\Delta$18) and a truncated N-terminal half lacking its first 18 amino acids ($\Delta$18N) have higher catalytic activity than other mutants tested. Similar results were obtained by PET-scan analysis using $^{18}F-FDG$. Our results collectively suggest that each domain of HK II possesses enzyme activity, unlike HK I, with the N-terminal half showing higher enzyme activity than the C-terminal half.

The Study for the Relation between Fatty Liver Diagnosed by Abdominal Ultrasonography and Hyperlipidemia (복부 초음파 검사로 진단된 지방간과 고지혈증 지표와의 관련성 연구)

  • Lee, Ga-Hul;Seok, Jong-Min;Jeon, Woo-Jin;KO, Eun-Ju;Lee, Jin
    • Journal of the Korean Society of Radiology
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    • v.13 no.4
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    • pp.531-537
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    • 2019
  • The purpose of this study was to analyze the relationship between hematologic hyperlipemia index and severity of fatty liver abdominal ultrasonography. A total of 412 adults from January 1, 2017 to December 31, 2017 who underwent abdominal ultrasonography and hematologic data within 3 months of the ultrasound examination, were the target of the investigation. As a result of the study, the hematological values according to the degree of fatty liver were statistically significant in triglyceride, AST and ALT (p<.05), fatty liver was associated with gender, triglyceride, AST and ALT (p<.05). In conclusion, the degree of fatty liver was not directly related to the hematologic value of hyperlipidemia, but we confirmed the necessity of co-management with fatty liver and hyperlipidemia by confirming its relevance.

Heating Characteristics Evaluation of Superposed Sonication Using Glycerol Tissue Mimic Phantom (글리세롤 조직유사 팬텀을 이용한 초음파 중첩 조사에 따른 가열 특성 평가)

  • Noh, Si-Cheol;Kang, Sang-Sik;Park, Ji-Koon;Kim, Ju-Young;Jung, Bong-Jae
    • Journal of the Korean Society of Radiology
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    • v.9 no.7
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    • pp.523-528
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    • 2015
  • In this study, we evaluated the heating characteristics of single sonication and superposed two low-intensity ultrasonic sonication. Compare the results, the superposed sonication was showed a superior thermal effect than single sonication. And the maximum temperature was increased as 120-150%. The starting time of temperature rising has been shortened in superposed sonication. In addition, the time up to the maximum temperature has been shortened, too. In generally, as the ultrasonic intensity is higher, the more surface damage is occurred. However, in the case of superposed sonication, the same thermal effect had be confirmed without surface damage. Through the results of the study, we thought that the superposed sonication will be able to reduce the intensity of the ultrasonic treatment. And, by using the low-intensity, the more safe and more effect therapy will be possible in therapeutic ultrasound application.

Sterilization Effect by the Nd:YAG Laser pulse (Nd:YAG 레이저 펄스에 따른 멸균효과)

  • Jeong, Kyeonghwan;Jung, Dongkyung;Park, Jeongkyu;Choi, Hyeonwoo;Seo, Jeongmin
    • Journal of the Korean Society of Radiology
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    • v.14 no.5
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    • pp.695-703
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    • 2020
  • The use of medical devices is increasing due to the development of medical technology. Among medical devices, it is often used in the human body for graft and treatment. Therefore, in medical institutions, various sterilization methods according to the type and material of medical devices are applied to prevent infection. Hydrophosphite (HA) materials are the most popular in bone grafts. We would like to present a sterilization method using Q-switch Nd:YAG laser with high output energy among non-ionizing radiation suitable for small medical devices. In this study, sterilization power was most ideally shown at UV wavelengths of 1.5 W, 266 nm, and 10 pulses. Different wavelength bands; infrared and visible light; showed passive sterilization, and ultraviolet A and C showed differences in sterilization according to the pulse. In laser sterilization were differences that found according to the wavelength bands and pulses.

Comparison of Image Uniformity with Photon Counting and Conventional Scintillation Single-Photon Emission Computed Tomography System: A Monte Carlo Simulation Study

  • Kim, Ho Chul;Kim, Hee-Joung;Kim, Kyuseok;Lee, Min-Hee;Lee, Youngjin
    • Nuclear Engineering and Technology
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    • v.49 no.4
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    • pp.776-780
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    • 2017
  • To avoid imaging artifacts and interpretation mistakes, an improvement of the uniformity in gamma camera systems is a very important point. We can expect excellent uniformity using cadmium zinc telluride (CZT) photon counting detector (PCD) because of the direct conversion of the gamma rays energy into electrons. In addition, the uniformity performance such as integral uniformity (IU), differential uniformity (DU), scatter fraction (SF), and contrast-to-noise ratio (CNR) varies according to the energy window setting. In this study, we compared a PCD and conventional scintillation detector with respect to the energy windows (5%, 10%, 15%, and 20%) using a $^{99m}Tc$ gamma source with a Geant4 Application for Tomography Emission simulation tool. The gamma camera systems used in this work are a CZT PCD and NaI(Tl) conventional scintillation detector with a 1-mm thickness. According to the results, although the IU and DU results were improved with the energy window, the SF and CNR results deteriorated with the energy window. In particular, the uniformity for the PCD was higher than that of the conventional scintillation detector in all cases. In conclusion, our results demonstrated that the uniformity of the CZT PCD was higher than that of the conventional scintillation detector.

Measurement of the Spatial Scattering Dose by Opening, Closing Door and Installing Shielding : A Study on the Reduction of Exposure Dose in Radiography (문 개폐 여부와 차폐체 설치 유무에 따른 공간산란선량 측정 : X선 촬영 시 피폭선량 감소방안에 대한 연구)

  • Yoon, Hong-Joo;Lee, Yong-Ki;Lee, In-Ja
    • Journal of radiological science and technology
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    • v.42 no.6
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    • pp.477-482
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    • 2019
  • Recently, due to the increased use of medical radiation, the radiation exposure of radiation workers should be considered as well as medical exposure of patients. And it is recommended to close the door during radiography. however, In this study, when the door was inevitably opened for radiography, the proposed method was to install the shield as a method of reducing the exposure dose. And its efficiency was analyzed. In simple chest radiography, the measurement point was changed according to the measurement location. Dose rate were measured 10 times for each condition using a dosimeter. And the average value was derived. Using this, the change of dose according to the opening and closing of the door and the installation of the shield was analyzed. Using this, we compared and analyzed the dose change according to the door opening and closing and the installation of the shield, and significance was verified through the SPSS ver. 24. Depending on whether the door was opened or closed, 11,215.35%, 159.0%, 101.9% increased in front of the door in the consol room, behind the wall and behind the lead glass. Depending on the installing of the shield, the 49.2%, 29.6%, 19.9%, 30.6% decrease in front of the door in the examination and consol room, behind the wall and lead glass. In addition, statistical analysis was showed that there were significant differences in both the results according to whether the door was opened or closed and shielding(p<.05). Close the door during radiography. However, when the door should be opened, it was confirmed that the dose rate were reduced by installing the shield. Therefore, to optimize radiation protection, it is recommended to install shields when opening the door.

Comparative Study on Usefulness of SPAIR and STIR Fast SE T2-weighted 3T Magnetic Resonance Imaging (3T 고속스핀에코 T2강조영상에서 지방소거 반전회복기법의 유용성 연구 - SPAIR와 STIR와의 비교 -)

  • Lee, Hoo-Min;Yoon, Joon;Yeo, Young-Bok
    • Journal of radiological science and technology
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    • v.33 no.1
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    • pp.45-50
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    • 2010
  • In this study, we compared the clinical usefulness of SPAIR (Spectral Adiabatic Inversion Recovery) and STIR (Short TI Inversion Recovery) to evaluate the fat tissues precisely. The images of brain axial (n = 20), lumber spine sagittal (n = 20), hip joint coronal (n = 17) and knee joint (n = 25) were obtained by turbo spin echo T2 weighted method on 3T magnetic resonance image. The signal intensity (SI) values were measured using region of interest in fat, muscle tissue, and background noise. The inhomogeneity values were measured using the standard deviation (SD) value divided by the mean values. SD signifies the amount of error which is similar to the imaging heterogeneity. In brain axial images, the SPAIR showed more superior SI and inhomogeneity results than the STIR. In spine, hip and knee images, STIR showed more excellent SI results, but poor inhomogeneity than the SPAIR.

Performance Characteristic of a CsI(Tl) Flat Panel Detector Radiography System (CsI(TI) Indirect Flat Panel Detector의 선질에 따른 물리적 영상 평가)

  • Jeong, Hoi-Woun;Min, Jung-Hwan;Kim, Jung-Min;Park, Min-Seok;Lee, Gaung-Young
    • Journal of radiological science and technology
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    • v.35 no.2
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    • pp.109-117
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    • 2012
  • The purpose of this work was to evaluate an amorphous silicon cesium iodide based indirect flat-panel detector (FPD) in terms of their modulation transfer function (MTF), Wiener spectrum (WS, or noise power spectrum, NPS), and detective quantum efficiency (DQE). Measurements were made on flat-panel detector using the International Electrotechnical Commission (IEC) defined RQA3, RQA5, RQA7, and RQA9 radiographic technique. The MTFs of the systems were measured using an edge method. The WS(NPS) of the systems were determined for a range of exposure levels by two-dimensional (2D). Fourier analysis of uniformly exposed radiographs. The DQEs were assessed from the measured MTF, WS(NPS), exposure, and estimated ideal signal-to-noise ratios. Characteristic curve in the RQA3 showed difference in the characteristic curve from RQA5, RQA7, RQA9. MTFs were not differences according to x-ray beam quality. WS(NPS) was reduced with increasing dose, and RQA 3, RQA5, RQA7, RQA9 as the order is reduced. DQE represented the best in the 1mR, RQA 3, RQA5, RQA7, RQA9 decrease in the order. The physical imaging characteristics of FPD may also differ from input beam quality. This study gives an initial motivation that the physical imaging characteristics of FPD is an important issue for the right use of digital radiography system.