• Journal of radiological science and technology
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• v.44 no.6
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• pp.599-605
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• 2021

The International Electrotechnical Commission (IEC) 62494-1 has defined the exposure index (EI) that have a proportional relationship with the dose incident on the image receptor, and target exposure index (EI_T), deviation index (DI). In this study, an appropriate EI_T for skull radiography was established through the diagnostic reference level (DRL) and changes in DI were confirmed. Entrance surface dose (ESD) and EI were obtained using the computed radiography system displayed the EI as per IEC on console and skull phantom by experiment based on the national average exposure conditions announced in 2012 and 2019. And appropriate EI_T was established by applying the DRL in 2012 and 2019. As a results, the EI_T is changed according to the change in the DRL, and the exposure condition that becomes the ideal DI according to the change in the EI_T also has a difference of about 1.41 times. DRL is recommended to optimize the patient dose, however it is difficult to measure in real time at medical institutions whereas EI and DI are displayed on the console at the same time as exposure. When the EI_T is set based on the DRL and the DI is closed to an ideal value, it is useful as a patient dose management tool. Therefore, when the EI_T is periodically managed along with the revision of the DRLs, the patient dose can be optimized through the EI, EI_T and DI.

• Korean Journal of Radiology
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• v.24 no.1
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• pp.51-61
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• 2023

Objective: To develop and test a machine learning model for classifying human papillomavirus (HPV) status of patients with oropharyngeal squamous cell carcinoma (OPSCC) using ¹⁸F-fluorodeoxyglucose (¹⁸F-FDG) PET-derived parameters in derived parameters and an appropriate combination of machine learning methods in patients with OPSCC. Materials and Methods: This retrospective study enrolled 126 patients (118 male; mean age, 60 years) with newly diagnosed, pathologically confirmed OPSCC, that underwent ¹⁸F-FDG PET-computed tomography (CT) between January 2012 and February 2020. Patients were randomly assigned to training and internal validation sets in a 7:3 ratio. An external test set of 19 patients (16 male; mean age, 65.3 years) was recruited sequentially from two other tertiary hospitals. Model 1 used only PET parameters, Model 2 used only clinical features, and Model 3 used both PET and clinical parameters. Multiple feature transforms, feature selection, oversampling, and training models are all investigated. The external test set was used to test the three models that performed best in the internal validation set. The values for area under the receiver operating characteristic curve (AUC) were compared between models. Results: In the external test set, ExtraTrees-based Model 3, which uses two PET-derived parameters and three clinical features, with a combination of MinMaxScaler, mutual information selection, and adaptive synthetic sampling approach, showed the best performance (AUC = 0.78; 95% confidence interval, 0.46-1). Model 3 outperformed Model 1 using PET parameters alone (AUC = 0.48, p = 0.047) and Model 2 using clinical parameters alone (AUC = 0.52, p = 0.142) in predicting HPV status. Conclusion: Using oversampling and mutual information selection, an ExtraTree-based HPV status classifier was developed by combining metabolic parameters derived from ¹⁸F-FDG PET/CT and clinical parameters in OPSCC, which exhibited higher performance than the models using either PET or clinical parameters alone.

• Progress in Medical Physics
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• v.19 no.2
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• pp.102-112
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• 2008

We developed a high-resolution micro-CT system based on rotational gantry and flat-panel detector for live mouse imaging. This system is composed primarily of an x-ray source with micro-focal spot size, a CMOS (complementary metal oxide semiconductor) flat panel detector coupled with Csl (TI) (thallium-doped cesium iodide) scintillator, a linearly moving couch, a rotational gantry coupled with positioning encoder, and a parallel processing system for image data. This system was designed to be of the gantry-rotation type which has several advantages in obtaining CT images of live mice, namely, the relative ease of minimizing the motion artifact of the mice and the capability of administering respiratory anesthesia during scanning. We evaluated the spatial resolution, image contrast, and uniformity of the CT system using CT phantoms. As the results, the spatial resolution of the system was approximately the 11.3 cycles/mm at 10% of the MTF curve, and the radiation dose to the mice was 81.5 mGy. The minimal resolving contrast was found to be less than 46 CT numbers on low-contrast phantom imaging test. We found that the image non-uniformity was approximately 70 CT numbers at a voxel size of ${\sim}55{\times}55{\times}X100\;{\mu}^3$. We present the image test results of the skull and lung, and body of the live mice.

• Investigative Magnetic Resonance Imaging
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• v.17 no.1
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• pp.8-18
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• 2013

Purpose : The purpose of this study was to find and categorize the various magnetic resonance imaging (MRI) findings of spinal metastases that correlate with the type of primary cancer. Materials and Methods: We retrospectively reviewed gadolinium-enhanced magnetic resonance images of 30 patients with 169 spinal metastatic lesions from lung cancer (n = 56), breast cancer (n = 29), colorectal cancer (n = 20), hepatocellular carcinoma (HCC) (n = 17), and stomach cancer (n = 47). The size, location, extent of invasion, signal intensity, margin, enhancement pattern, and osteoblastic or osteolytic characteristics of each metastatic tumor were analyzed. Results: The metastatic lesions from HCC were larger than those from the other primary tumors (P < 0.05) except for colorectal cancer (P = 0.268). Well-defined metastatic tumor margins were more frequently seen in lung cancer and breast cancer (P < 0.01). All but HCC showed a tendency to invade the vertebral body rather than the posterior elements (P < 0.02). Colorectal cancer and HCC showed a tendency toward extraosseous invasion without statistical significance. HCC showed a characteristic enhancement pattern of 'worms-in-a-bag'. Rim enhancement with a sclerotic center was only seen in spinal metastases from stomach cancer. Conclusion: Despite many overlapping imaging features, spinal metastases of various primary tumors display some characteristic MRI findings that can help identify the primary cancer.

• Journal of the Korean Society of Radiology
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• v.7 no.4
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• pp.259-264
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• 2013

Total body irradiation in the treatment of childhood leukemia, which is one of the pre-treatment with stem cell transplantation is being used, the current organization using compensators are treated. However, under the terms of the compensator organization long-term impact on the human body, it is difficult to assess directly. In this study, we use the mathematical simulation of radiation exposures body energy and the distance to the crew and the patient (source surface distance, SSD), and patients with tissue compensators change of the distance along the body of the organ doses were evaluated. As a result, the surface dose of energy 4 MV, SSD 280 cm, tissue compensators and the patient when the distance 30 cm 5.84 G / min showed the highest levels. In addition, patients with tissue compensators and the distance apart when 30 cm TBI represents the ideal dose distribution was found.

• Journal of the Korean Society of Radiology
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• v.4 no.2
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• pp.21-25
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• 2010

Recently, various semiconductor compounds as radiation detection material have been researched for a diagnostic x-ray detector application. In this paper, we have fabricated the CdS detecton sensor that has good photosensitivity and high x-ray absorption efficiency among other semiconductor compounds, and evaluated the application feasibility by investigating the detection properties about energy range of diagnostic x-ray generator. We have fabricated the line voltage selector(LCV) for a signal acquisition and quantities of CdS sensor, and designed the voltage detection circuit and rectifying circuit. Also, we have used a relative relation algorithm according to x-ray exposure condition, and fabricated the interface board with DAC controller. Performance evaluation was investigated by data processing using ANOVA program from voltage profile characteristics according to resistive change obtained by a tube voltage, tube current, and exposure time that is a exposure condition of x-ray generator. From experimental results, an error rates were reduced according to increasing of a tube voltage and tube current, and a good properties of 6%(at 90 kVp) and 0.4%(at 320 mA) ere showed. and coefficient of determination was 0.98 with relative relation of 1:1. The error rate according to x-ray exposure time showed exponential reduction because of delayed response velocity of CdS material, and the error rate has 2.3% at 320 msec. Finally, the error rate according to x-ray dose is below 10%, and a high relative relation was showed with coefficient of determination of 0.9898.

• Journal of the Korean Society of Radiology
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• v.15 no.7
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• pp.1049-1056
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• 2021

The purpose of this study was to develop a respiratory synchronization device for X-ray (X-RSD) to increase the reproducibility of inspiration when examining the Chest X-ray of a patient who difficulty in breathing coordination. The X-RSD was self-made using an air pressure sensor and air was injected by connecting a ventilator to the mannequin for CPR. At this time, the amount of injected air was quantified using the SkillReporting device. After placing the X-RSD on the chest of the mannequin, the amount of air was tested in 6 steps from 200 to 700 cc by 100 cc increased. For the accuracy evaluation, the sensitivity of X-RSD was measured by repeating a total of 80 measurements, and the sensitivity was 100%, and very precise results were obtained. After that, the images examined while viewing the X-RSD of the chest lateral examination and the images obtained by the blind examination were compared and evaluated. The lung volume of X-RSD was larger than that of the blind test, and the deviation was smaller. Overall, the use of X-RSD can help with chest X-ray examination of patients who have difficulty in cooperating, and it is thought that it will be possible to contribute to the reduction of exposure dose by reducing the repeat rate of general X-ray examinations.

• Journal of the Korean Society of Radiology
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• v.10 no.2
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• pp.81-87
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• 2016

In this study we proposed a texture feature analysis algorithm that distinguishes between a normal image and a diseased image using CT images of some fatty liver patients, and generates both Eigen images and test images which can be applied to the proposed computer aided diagnosis system in order to perform a quantitative analysis for 6 parameters. And through the analysis, we derived and evaluated the recognition rate of CT images of fatty liver. As the results of examining over 30 example CT images of fatty liver, the recognition rates representing a specific texture feature-value are as follows: some appeared to be as high as 100% including Average Gray Level, Entropy 96.67%, Skewness 93.33%, and Smoothness while others showed a little low disease recognition rate: 83.33% for Uniformity 86.67% and for Average Contrast 80%. Consequently, based on this research result, if a software that enables a computer aided diagnosis system for medical images is developed, it will lead to the availability for the automatic detection of a diseased spot in CT images of fatty liver and quantitative analysis. And they can be used as computer aided diagnosis data, resulting in the increased accuracy and the shortened time in the stage of final reading.

• Journal of radiological science and technology
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• v.44 no.3
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• pp.225-229
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• 2021

The digital image such as medical X-ray and nuclear medicine field mainly contains noise distribution. The noise degree in image degrades image quality. That is why, the noise reduction algorithm is efficient for medical image field. In this study, we confirmed effectiveness of application for median modified Wiener filter (MMWF) algorithm for noise reduction in PET/MR image compared with median filter image, which is used as conventional noise redcution algorithm. The Jaszczak PET phantom was used by using 18F solution and filled with NaCl+NiSO4 fluids. In addition, the radioactivity ratio between background and six spheres in the phantom is maintained to 1:8. In order to mimic noise distribution in the image, we applied Gaussian noise using MATLAB software. To evlauate image quality, the contrast to noise ratio (CNR) and coefficient of variation (COV) were used. According to the results, compared with noise image and images with MMWF algorithm, the image with MMWF algorithm is increased approximately 33.2% for CNR result, decreased approximately 79.3% for COV result. In conclusion, we proved usefulness of MMWF algorithm in the PET/MR images.

• Journal of the Korean Society of Radiology
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• v.1 no.1
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• pp.25-30
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• 2007

ROC(Receiver Operating Characteristic)curve is the method that estimate detected insignificant signal from the human's sense of sight, it has been raised excellent results. In this study, we evaluate image quality and equipment character by obtaining a chest image from CR(Computed Radiography) and DDR(Direct Digital radiography) using the human chest phantom, The parameter of exposure for obtaining chest image was 120 kVp/3.2 mAs and the SID(Source to Image Distance) was 180cm. The images were obtained by CR(AGFA MD 4.0 General plate, JAPAN) and DDR(HOLOGIC nDirect Ray, USA). Using some pieces of Aluminum and stone for expressing regions, then attached them on the heart, lung and thoracic vertebrae of the phantom. 29 persons hold radiology degrees were participated in ROC analysis. As a result of the ROC analysis, TPF(true positive fraction) and FPF(false positive fraction) of DDR and CR are 0.552 and 0.474 and 0.629 and 0.405, respectively. By using the results, the ROC curve of CR has higher image quality than DDR. According to the theory, DDR has the higher image quality than CR in chest X-ray image. But, CR has the higher image quality than DDR. quality of DDR inserted the enhance board. The results confirmed that image post-processing is important element decipherment of clinical.