• Journal of Korean Neurosurgical Society
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• 제44권3호
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• pp.109-115
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• 2008

When a tear occurs in one of the major cervicocerebral arteries and allows blood to enter the wall of the artery and split its layers, the result is either stenosis or aneurysmal dilatation of the vessel. Vertebral artery dissection (VAD) is an infrequent occurrence but is a leading cause of stroke in young and otherwise healthy patients. This article discusses recent developments in understanding of the epidemiology and pathogenesis of VAD and the various clinical manifestations, methods of diagnosis, and approaches to treatment.

• Journal of Korean Neurosurgical Society
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• 제29권3호
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• pp.420-425
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• 2000

Epidural steroid injection(ESI) has been a commonly applied conservative therapy for the management of chronic low back pain and sciatica. However, there are many reports concerning various local, systemic and neurological complications related to ESI. We report two cases with fatal complications after ESI for low back pain and sciatica. In both patients, ventriculitis and meningitis were causative factors to be fatal. Aseptic procedures and careful post-procedure assessment are essential to avoid serious complications following ESI.

• Journal of Korean Neurosurgical Society
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• 제29권6호
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• pp.800-804
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• 2000

Cerebral paragonimiasis is an important parasitic infestation found in Eastern Asia, West Africa, and Central/South America. It is frequently associated with abscess, granuloma or cystic lesions in chronic stage. Chronic symptoms include seizure, visual disturbance, movement and perception disorders, usually resulting from the spaceoccupying lesions. The authors report a case of chronic cerebral paragonimiasis combined with meningioma. A 69-year-old man presented with generalized seizure and impaired consciousness. CT scan and MR image of the brain revealed two intracranial lesions ; one was cerebral paragonimiasis in the left temporo-occipital lobe, and the other a huge falx meningioma. Two lesions were successfully removed in staged operations and the generalized seizure was controlled after removal of the cerebral paragonimiasis.

• Journal of Korean Neurosurgical Society
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• 제30권sup1호
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• pp.133-136
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• 2001

Maffucci's syndrome is generally characterized by chondromatosis with vascular lesions of mesodermal origin, however, intracranial chondroma is rare. We present a case of Maffucci syndrome with paracellar chondroma and the review of literatures.

• Journal of Korean Neurosurgical Society
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• 제30권sup1호
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• pp.137-139
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• 2001

The authors report a 42-year-old woman presented with a falx meningioma with disproportionately severe peritumoral edema. Histological examination including immunohistochemical staining resulted in the diagnosis of secretory meningioma. In addition to tumor size, edema could not be explained by location, growth rate, vascular involvement, or other factors. We conclude that secretory meningiomas may possess an innate ability to cause brain edema.

• 대한치매학회지
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• 제22권1호
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• pp.46-48
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• 2023

• Journal of Korean Neurosurgical Society
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• 제30권1호
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• pp.89-94
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• 2001

Skull or brain metastasis from thyroid carcinoma is rare. Between Jan. 1993. and Jan. 2000. the authors experienced 7 cases of skull(4 cases) or brain(3 cases) metastasis from thyroid carcinoma. Clinical characteristics, radiologic findings and pathologic features were analyzed retrospectively. Among 4 cases of skull metastasis, 3 cases were follicular carcinoma and one was papillary carcinoma with follicular variant. All cases of brain metastasis were papillary carcinoma. We treated the patients by combination with surgical resection, radioactive iodine therapy and radiation therapy. Characteristics of skull or brain metastasis from thyroid carcinoma is reviewed with a pertinent literature.

• 대한핵의학회:학술대회논문집
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• 대한핵의학회 2003년도 추계학술대회 및 총회
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• pp.11.1-11.1
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• 2003

• Journal of Korean Neurosurgical Society
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• 제64권4호
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• pp.608-618
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• 2021

Objective : The endoscopic endonasal transsphenoidal approach is a widely-used method for the surgical treatment of pituitary adenomas. We aimed to evaluate the results of endoscopic surgery by comparing preoperative classification methods and investigating their relationship with postoperative resection and remission rates and complications. Methods : We retrospectively reviewed the medical records of 236 patients (118 males) who underwent surgery for pituitary adenomas. Preoperative Knosp classification, tumor size (TS), suprasellar extension (SSE), postoperative resection and remission rates, and complications were evaluated. Results : The follow-up period was 3 months to 6 years. The patients' ages ranged between 16 and 84 years. Endocrinologically, 114 patients (48.3%) had functional adenoma (FA), and 122 patients (51.7%) had non-functional adenoma (NFA). Among the FA group, 92 (80.7%) showed remission. A statistically significant difference was found between patients with and without remission in terms of the Knosp, TS, and SSE classifications (p<0.01). Knosp, TS, and SSE classification grades were found to be correlated with the resection rates (p<0.01). Meningitis was seen in seven patients (3.0%), diabetes insipidus in 16 (6.9%; permanently in two [0.9%]), and rhinorrhea in 19 (8.1%). Thirty-six patients (15.3%) developed pituitary insufficiency and received hormone replacement therapy. Conclusion : The resection categories and remission rates of FAs were directly proportional to the adenoma sizes and Knosp grades, while the degree of suprasellar growth further complicated resection and remission rates. Adenoma sizes less than 2 cm and SSEs less than 1 cm are associated with favorable remission and resection rates.

• Asian Pacific Journal of Cancer Prevention
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• 제16권13호
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• pp.5319-5323
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• 2015

Background: The purpose of this study was to evaluate the prognostic significance of Ki-67 and subjective microvascular density (SMVD) indexes together with other factors in patients with oligodendroglioma. Materials and Methods: In this retrospective study, oligodendroglioma specimens obtained from twenty-five consecutive patients were evaluated for Ki-67 and SMVD indices to help determine histological grading and investigate the fidelity of these markers in clinical prognosis. Other potentially prognostic factors were Karnofsky performance scale, tumor histological grade, and adjuvant radiotherapy. Results: The Ki-67 proliferation index appeared to have a strong correlation with the grade of the tumor and the survival. Age, gender, adjuvant radiotherapy, surgical resection type (complete versus incomplete) did not have any influence on recurrence. The SMVD index correlated significantly with the 3 to 5-year survival. Conclusions: Ki-67 and MVD indexes are important and useful markers in estimating the prognosis of oligodendrogliomas.