• 한국의학물리학회:학술대회논문집
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• 한국의학물리학회 2004년도 제29회 추계학술대회 발표논문집
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• pp.100-103
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• 2004

본 연구에서는 PET/CT시스템에서 CT영상을 이용한 감쇠 보정 시 조영제가 PET영상에 미치는 영향을 관찰하기 위해 팬텀실험과 모의실험을 수행하였다. 다양한 농도로 희석한 조영제를 채운 플라스틱 병을 스티로폼을 이용하여 전신 팬텀 내에 고정시킨 후 투과 영상을 획득하였다. 모의실험을 위해 인체 기관 중 간을 가진 수학적 방출 스캔 맵과 투과 스캔 맵을 각각 만들었다. 간에서 조영제가 비 균일하게 증강된 투과 스캔 맵, 간에 조영제의 증강이 있는 투과스캔 맵과 없는 투과 스캔 맵, 간에 있는 종양에 조영제의 hypo-attenuating이 있는 투과 스캔 맵, 그리고 각각의 다른 조영제의 감쇠 정도를 가지는 간을 구현한 투과 스캔 맵을 각각 만들고 이를 이용하여 방출 영상을 감쇠 보정하였다. 팬텀실험을 통해 조영제의 농도에 따라 감쇠 정도가 달라짐을 확인하였다. 모의실험을 통해 감쇠 보정된 방출 영상이 조영제에 의해 영향을 받고, 또한 인공산물이 발생할 수 있음을 확인하였다. 따라서 조영제와 같은 물리적 인자가 감쇠 보정에 미치는 영향을 충분히 이해하고 정량적 분석 또는 진단 등에 고려하여야 할 것으로 생각한다.

• 한국정보통신학회:학술대회논문집
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• 한국해양정보통신학회 2009년도 춘계학술대회
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• pp.419-421
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• 2009

얼음의 경우 주변의 압력, 습도 등의 환경에 따라서 결빙점이 달라지는데 얼음의 투명도를 측정함으로써 얼음의 결빙 과정을 유추할 수 있고 얼음의 밀도 등의 특징을 파악하는데 도움이 된다. 본 논문은 이미지 상에 포함되어 있는 얼음의 투명도를 측정하는 방법을 제시하고자 한다. 얼음이 포함된 이미지를 먼저 $CIEL^*a^*b^*$ 색 공간으로 변경한 후, $L^*$ 값의 평균과 RMS(Root Mean Square) Contrast를 조합해서 얼음의 투명도를 측정하는 지수를 만들었다. 얼음 이미지의 경우 Wever Contrast나 Michelson Contrast 등 기존의 컨트라스트 비교에 비해 훨씬 만족할만한 성능을 보여주었다.

• 천문학회지
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• 제17권2호
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• pp.115-125
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• 1984

Effect of magnetic field on the thermal instability is studied in the radiatively cooling region behind an interstellar shock of moderate propagation velocity (${\sim}10\;km/sec$). It is shown that the presence of interstellar magnetic field of a few micro gauss is very effective in preventing the thermal instability from building-up density concentration. In the absence of magnetic field, the shock-induced thermal instability amplifies preshock density inhomogeneity by more than an order of magnitude. However, in the presence of magnetic field, the amplified density contrast is shown to be only a factor 2.

• Korean Journal of Radiology
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• 제22권11호
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• pp.1909-1917
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• 2021

Objective: Muscle quantity and quality can be measured with an automated system on CT. However, the effects of contrast phases on the muscle measurements have not been established, which we aimed to investigate in this study. Materials and Methods: Muscle quantity was measured according to the skeletal muscle area (SMA) measured by a convolutional neural network-based automated system at the L3 level in 89 subjects undergoing multiphasic abdominal CT comprising unenhanced phase, arterial phase, portal venous phase (PVP), or delayed phase imaging. Muscle quality was analyzed using the mean muscle density and the muscle quality map, which comprises normal and low-attenuation muscle areas (NAMA and LAMA, respectively) based on the muscle attenuation threshold. The SMA, mean muscle density, NAMA, and LAMA were compared between PVP and other phases using paired t tests. Bland-Altman analysis was used to evaluate the inter-phase variability between PVP and other phases. Based on the cutoffs for low muscle quantity and quality, the counts of individuals who scored lower than the cutoff values were compared between PVP and other phases. Results: All indices showed significant differences between PVP and other phases (p < 0.001 for all). The SMA, mean muscle density, and NAMA increased during the later phases, whereas LAMA decreased during the later phases. Bland-Altman analysis showed that the mean differences between PVP and other phases ranged -2.1 to 0.3 cm² for SMA, -12.0 to 2.6 cm² for NAMA, and -2.2 to 9.9 cm² for LAMA.The number of patients who were categorized as low muscle quantity did not significant differ between PVP and other phases (p ≥ 0.5), whereas the number of patients with low muscle quality significantly differed (p ≤ 0.002). Conclusion: SMA was less affected by the contrast phases. However, the muscle quality measurements changed with the contrast phases to greater extents and would require a standardization of the contrast phase for reliable measurement.

• Korean Journal of Radiology
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• 제24권9호
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• pp.849-859
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• 2023

Objective: The prognostic value of the volume and density of skeletal muscles in the abdominal waist of patients with colon cancer remains unclear. This study aimed to investigate the association between the automated computed tomography (CT)-based volume and density of the muscle in the abdominal waist and survival outcomes in patients with colon cancer. Materials and Methods: We retrospectively evaluated 474 patients with colon cancer who underwent surgery with curative intent between January 2010 and October 2017. Volumetric skeletal muscle index and muscular density were measured at the abdominal waist using artificial intelligence (AI)-based volumetric segmentation of body composition on preoperative pre-contrast CT images. Patients were grouped based on their skeletal muscle index (sarcopenia vs. not) and muscular density (myosteatosis vs. not) values and combinations (normal, sarcopenia alone, myosteatosis alone, and combined sarcopenia and myosteatosis). Postsurgical disease-free survival (DFS) and overall survival (OS) were analyzed using univariable and multivariable analyses, including multivariable Cox proportional hazard regression. Results: Univariable analysis showed that DFS and OS were significantly worse for the sarcopenia group than for the non-sarcopenia group (P = 0.044 and P = 0.003, respectively, by log-rank test) and for the myosteatosis group than for the non-myosteatosis group (P < 0.001 by log-rank test for all). In the multivariable analysis, the myosteatotic muscle type was associated with worse DFS (adjusted hazard ratio [aHR], 1.89 [95% confidence interval, 1.25-2.86]; P = 0.003) and OS (aHR, 1.90 [95% confidence interval, 1.84-3.04]; P = 0.008) than the normal muscle type. The combined muscle type showed worse OS than the normal muscle type (aHR, 1.95 [95% confidence interval, 1.08-3.54]; P = 0.027). Conclusion: Preoperative volumetric sarcopenia and myosteatosis, automatically assessed from pre-contrast CT scans using AI-based software, adversely affect survival outcomes in patients with colon cancer.

• Imaging Science in Dentistry
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• 제33권1호
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• pp.21-26
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• 2003

Purpose: To investigate the characteristics of the newly marketed, Insight dental X-ray film. Materials and Methods: Kodak Ultraspeed (DF-58), E-speed, Agfa Dentus M2, and Kodak Insight (IP-21) films were radiographed using a Trophy intra-oral radiographic machine. 10 step exposure times were prepared and each step exposure was monitored using a FH 40G (ESM Eberline Instruments) dosimeter for each of the 4 types of intra-oral film. All films were manually processed and the radiographic densities at 6 sites of each processed film were measured, and the characteristic curves of each of the 4 types intra-oral films were created utilizing these dosimetric data and radiographic densities, based on ISO 5779. The film contrast, speed, and base plus fog density of Insight film were compared with those of the 3 other films examined in this experiment. Results : E-speed film showed greatest average gradients followed by Insight film. E-speed and Ultraspeed film showed great average gradients at low density levels. Insight film showed the fastest speed followed by E-speed, Dentus M2 and Ultraspeed film. Dentus M2 film showed greatest base plus fog density level followed by Insight film. Conclusion : Kodak Insight film showed fastest film speed with comparable film contrast on characteristic curve.

• Bulletin of the Korean Chemical Society
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• 제20권10호
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• pp.1177-1180
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• 1999

The ab initio SCF MO and density functional theory (DFT) studies are carried out on the electrophilic (1a) and electron transfer (1b) addition reactions to the vinyl double bond of aryl vinyl sulfides and ethers. In the electrophilic addition processes, a double bond shift from C3 = C4 to X = C3 occurs with occupation number (1.97) close to the normal two. Due to this shift direct conjugation between the cationic center, X = S or O, and the para electron-donor substituent becomes impossible so that the reaction energies (or log K) are correlated with σ rather than σ+. By contrast, radical cation formation leads to delocalization of the SOMO, a lone-pair πorbital on X, with four major resonance structures in which cationic charge as well as spin density is delocalized over C4 , X and C7 atoms. As a result, partial πbonds are formed over C1 -X and C3 - C4 with occupation numbers (0.82) lower than one. In two of the cannonical structures, III(Ⅹ) and III(X+), direct conjugation between the cationic center, X, and the para substituent is achieved so that a better correlation with σ+ rather than σis obtained. The SCF MO energies at the HF/3-21G* and HF/6-31G* levels lead to very much inferior Hammett correlations in the σ/ σ+ diagnostic criterion. In contrast, the ρvalues evaluated with the DFT energies can give reliable diagnostic distinction between the two addition mechanisms.

• 한국방사선학회논문지
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• 제17권3호
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• pp.417-422
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• 2023

본 연구는 CT 검사 시 조영제로 기인한 화질 저하와 부작용을 감소시키기 위한 목적으로 식염수를 조영제에 일정 비율로 희석하였다. 이때 희석 정도에 따른 영상의 대조도 감소를 보상할 수 있는 DECT의 에너지 준위를 찾아 SNR, CNR, SSIM을 적용하여 비교 분석을 통해 영상 대조도 차 보상을 위한 DECT 적용의 유용성을 알아보았다. 그 결과 희석률 4(조영제) : 6(생리식염수), DECT의 에너지 준위 65 keV적용 시 조영제 원액을 사용했을 때와 가장 유사한 대조도 차가 형성되었고, 이때 SNR은 813.71±37.6, CNR은 921.87±17.1로 가장 높았으며, SSIM index가 1에 가장 유사한 0.851로 측정되었다. 본 연구결과는 향후 임상연구를 통해 검사부위별 적정 희석률과 에너지 레벨을 찾는 데 있어 기초정보를 제공하는 데 의미가 있으며 추가임상연구 결과를 임상에 적용한다면 조영제로 기인한 화질 저하와 부작용 문제를 줄여줄 수 있을 것으로 사료된다.

• Journal of Yeungnam Medical Science
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• 제39권1호
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• pp.24-30
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• 2022

Background: Texture analysis has been used as a method for quantifying image properties based on textural features. The aim of the present study was to evaluate the usefulness of magnetic resonance imaging (MRI) texture analysis for the evaluation of viable ovarian tissue on the perfusion map of ovarian endometriosis. Methods: To generate a normalized perfusion map, subtracted T1-weighted imaging (T1WI), T1WI and contrast-enhanced T1W1 with sequences were performed using the same parameters in 25 patients with surgically confirmed ovarian endometriosis. Integrated density is defined as the sum of the values of the pixels in the image or selection. We investigated the parameters for texture analysis in ovarian endometriosis, including angular second moment (ASM), contrast, correlation, inverse difference moment (IDM), and entropy, which is equivalent to the product of area and mean gray value. Results: The perfusion ratio and integrated density of normal ovary were 0.52±0.05 and 238.72±136.21, respectively. Compared with the normal ovary, the affected ovary showed significant differences in total size (p<0.001), fractional area ratio (p<0.001), and perfusion ratio (p=0.010) but no significant differences in perfused tissue area (p=0.158) and integrated density (p=0.112). In comparison of parameters for texture analysis between the ovary with endometriosis and the contralateral normal ovary, ASM (p=0.004), contrast (p=0.002), IDM (p<0.001), and entropy (p=0.028) showed significant differences. A linear regression analysis revealed that fractional area had significant correlations with ASM (r²=0.211), IDM (r²=0.332), and entropy (r²=0.289). Conclusion: MRI texture analysis could be useful for the evaluation of viable ovarian tissues in patients with ovarian endometriosis.

• 한국인쇄학회지
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• 제27권1호
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• pp.15-27
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• 2009

Since domestic offset print quality control depends on the experience of persons in charge rather than objective data, the standards from the data are needed for the well-organized quality management of high-quality prints. Based on the ISO standards, now the standard specifications, such as GRACoL 7, SWOP 11, SNAP, G7 in America, and EURO Color, ECI, BVDM in Europe, and Japan Color 2001, Japan Color 2004 in Japan, are employed. There exists KS for domestic standards. However, since it has been directly imported from ISO Standards, there are discrepancies in printing materials and media. Although the quality management of commercial prints has been focused and studied. For this circumstance, standards are needed for the production of prints to meet international standards. This paper aims to find out suitable ways to approach domestic printing standards using densitometric method and colorimetric method. Printing experiments on this study were performed with domestic process color inks(Cyan, Magenta, Yellow, Black) and domestic coated papers, under the same conditions as the actual commercial printing processes. In densitometric method, how to set up the optimal solid print density was studied through three tests such as the ways to match solid print density and print contrast to GRACoL standards respectively, and the way to get the highest contrast. In colorimetric method, how to get solid print density with the minimum color difference between the $CIEL^*a^*b^*$ color specification values in GRACoL standards and the measured color specification values in prints, was studied.