• Clinical and Experimental Pediatrics
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• v.62 no.10
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• pp.386-394
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• 2019

Background: Preterm infants have difficulty maintaining body temperature after birth. However, clinical guidelines advocate that neonatal body temperature should be maintained at 36.5℃-37.5℃. Purpose: We aimed to investigate the incidence of admission hypothermia in very low birth weight (VLBW) infants and to determine the association of admission temperature with in-hospital mortality and morbidities. Methods: A cohort study using prospectively collected data involving 70 neonatal intensive care units (NICUs) that participate in the Korean Neonatal Network. From registered infants born between January 2013 and December 2015, 5,343 VLBW infants born at less than 33 weeks of gestation were reviewed. Results: The mean admission temperature was 36.1℃±0.6℃, with a range of 31.9℃ to 38.4℃. Approximately 74.1% of infants had an admission hypothermia of <36.5℃. Lower birth weight, intubation in the delivery room and Apgar score <7 at 5 minutes were significantly related to admission hypothermia. The mortality was the lowest at 36.5℃-37.5℃ and adjusted odd ratios for all deaths increased to 1.38 (95% confidence interval [CI], 1.04-1.83), 1.44 (95% CI, 1.05-1.97) and 1.86 (95% CI, 1.22-2.82) for infants with admission temperatures of 36.0℃-36.4℃, 35.0℃-35.9℃, and <35.0℃, respectively. Admission hypothermia was also associated with high likelihoods of bronchopulmonary dysplasia, pulmonary hypertension, proven sepsis, pulmonary hemorrhage, air-leak, seizure, grade 3 or higher intraventricular hemorrhage and advanced retinopathy of prematurity requiring laser therapy. Conclusion: A large portion of preterm infants in Korea had hypothermia at NICU admission, which was associated with high mortality and several important morbidities. More aggressive interventions aimed at reducing hypothermia are required in this high-risk population.

• Clinical and Experimental Pediatrics
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• v.46 no.2
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• pp.192-194
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• 2003

A neonate born at 38 gestational weeks was admitted due to generalized tonic-clonic seizure and cyanosis. The neonate was born six days previously at home through normal delivery and the umbilical cord was cut using scissors sterilized in boiling water. The neonate weighed 3,180 g at admission. Physical examination revealed cyanosis, opisthotonus, trismus and reactive muscle spasms. Laboratory exam, brain sonogram and EEG showed no significant abnormal findings. Based on her history and physical examination, the neonate was diagnosed with tetanus and put in an incubator isolated in a quiet, dark room. Treatment with tetanus human immunoglobulin along with antibiotics (penicillin G) were started immediately, and mechanical ventilation, administration of neuromuscular blocking agent and muscle relaxant were also started off. The frequency of seizure episode decreased gradually, and on the 32nd hospital day, mechanical ventilatory support was stopped along with extubation two days later. Thereafter, the neonate was in continuous generalized hypertonic state and showed feeding difficulty, but there was gradual improvement. She was dismissed on the 49th hospital day and is currently under OPD follow-up, doing well with no special problems. Respiratory management is critical to neonatal tetanus. We report here a case of tetanus treated with inhibition of self-respiration, neuromuscular blocker and application of ventilator, and present this method as a useful direction for future treatment of neonatal tetanus.

• Particle and aerosol research
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• v.7 no.3
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• pp.87-97
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• 2011

In this study, we organized the test results obtained from the performance tests for the CA certificated air cleaners which had been commercially available in Korea since 2003, and analyzed the correlation among the test parameters such as flow rate, particle collection efficiency, clean air delivery rate (CADR), ozone emission, odor removal efficiency and noise level etc. The noise level of 267 air cleaners were increased as concentrated at the 45, 50, 55 dB, which are the required noise level for CA certification according to flow rate, and ozone emissions from the CA air cleaners were significantly lower than the requirement limit, 50 ppb for 24 hour operation. The average particle collection efficiency and odor removal efficiency were 89.3 and 80.8%, approximately 20% higher than the requirement of CA certification, regardless of flow rates. The particle removal performance of an air cleaner was clearly discriminated by its CADR, and the CADR was obtained with a simple calculation: 0.79 x flow rate. The low differentiation of gas removal performance of air cleaners by the current CA gas test method was improved by 3.2, 751.3, 13.4 times for ammonia, acetic acid, respectively, by adopting the CADR concept and the real time measurement method, FTIR, for gas removal performance test.

• Journal of muscle and joint health
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• v.6 no.1
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• pp.37-50
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• 1999

The purpose of this study was to identify the risk factors of osteoporosis. The data were collected from women who visited Physical Examination Center of a university hospital located in Taejon during the period of September 1997-August 1998. The sample was divided into two groups(the osteoporosis group of 44 cases and the control group of 66 cases). The results were summarized as follows ; 1. Sociodemographic characteristics(education and family income) and BMI showed no significant difference between the osteoporosis group and the control group. 2. There was no significant difference in coffee, unbalanced diet, diet method and meal habit between the osteoporosis group and the control group. 3. The osteoporosis group reported more incidence of operative menopause due to hysterectomy and oophorectomy, but this was not statistically significant. There was no significant difference in use of oral pill use, past disease and family history of fracture between the osteoporosis group and the control group, but the odds ratio(OR 3.11, 95% CI : 1.30-7.41) of present illness was statistically significant in the osteoporosis group. 4. There was no significant difference in the reproductive history including number of delivery and abortion and feeding method between the osteoporosis group and the control group. 5. The osteoporosis group showed significant results of lower menopausal age, shorter duration of menstruation and longer duration after menopause compared to the control group. 6. The osteoporosis group reported significantly lower level of physical activity in such variables as work activity and walking time. 7. A logistic analysis showed that shorter period of menstruation, lower level of physical activity, non-alcohol drinking group, and presence of disease were related to the possibility of occurring of osteoporosis.

• Korean Journal of Materials Research
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• v.13 no.11
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• pp.737-741
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• 2003

Polycrystalline $Ti_{l-x}$ $Co_{x}$ $O_2$thin films on $SiO_2$ (200 nm)/Si (100) substrates were prepared using liquid-delivery metalorganic chemical vapor deposition. Microstructures and ferromagnetic properties were investigated as a function of doped Co concentration. Ferromagnetic behaviors of polycrystalline films were observed at room temperature, and the magnetic and structural properties strongly depended on the Co distribution, which varied widely with doped Co concentration. The annealed $Ti_{l-x}$ $Co_{x}$ $O_2$thin films with $x\leq$0.05 showed a homogeneous structure without any clusters, and pure ferromagnetic properties of thin films are only attributed to the X$l-x_{l-x}$ $Co_{x}$X$O_2$phases. On the other hand, in case of thin films above x = 0.05, Co-rich clusters formed in a homogeneous $Ti_{l-x}$ $Co_{x}$ $O_2$phase, and the overall ferromagnetic (FM) properties depended on both FMTCO and FMCo. Co-rich clusters with about 10-150 nm size decreased the value of Mr (the remanent magnetization) and increased the saturation magnetic field.

• Journal of Korean Public Health Nursing
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• v.8 no.1
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• pp.84-102
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• 1994

This study was conducted to provide basic policy of home care service centered on early discharging patients from general hospitals. This subjects for this study were 291 discharging patients from university hospital in Chon-ju area. The data were collected during the period from July 1, 1993 through July 16, 1993. The measurement tools were developed based on 9 categorized human responses patterns suggested by NANDA and modified by the research team. The collected data were processed with SPSS/PC + frequency, percentage and mean were used for analysis. From the study, the following summerized conclusions have been drown. A. For home care needs, the mean was $19.0\%$ of possible to total 100 and in a range of $6.2\~39.5\%$ 1. Exchanging Pattern: $17.8\%$ 2. Communication Pattern: $8.6\%$ 3. Relating Pattern : $15.4\%$ 4. Valuing Pattern: $13.4\%$ 5. Choosing Pattern : $6.2\%$ 6. Moving Pattern : $22.9\%$ 7. Perceiving Pattern: $16.5\%$ 8. Knowing Pattern : $30.8\%$ 9. Feeling Pattern : $39.5\%$ B. Response to home care services, 1. $85.6\%$ of subjects didn't hear about home care service. 2. Over $90.0\%$ subjects approved home care service. 3. $83.5\%$of subjects were willing to use home care service. 4. $85.9\%$ of subjects will follow to early discharge order. On the basis of this findings, further studies are required to compare home care needs between patients, their family and community health people groups. And also required to develop to information strategies for home care nursing service.

• Korean Institute of Interior Design Journal
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• v.24 no.6
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• pp.154-162
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• 2015

As there is no case study with current status, measurements or description on the state of actual site of rural area only, the delivery of actual conditions about such an area is significantly limited. The purpose of this study is to pinpoint issues with housing conditions of low-income family with disabled members in the rural area. For such a purpose, 25 households of disabled people have been visited for interview, on-site research and survey, of which results are summed up in this paper as following: First, average monthly income of such family turned out to be KRW 480,000, most of which is from the government subsidy. High ratio of such families has resided in a house with average size of approximately 56m2 for about 24 years. Secondly the most needed maintenance work with top priority was for the toilet, and many of the interviewees expressed their discomfort about small size of their bathrooms and inconvenient facilities therein. Thirdly, most of such houses had too high thresholds that posed danger and inconvenience. Such thresholds had average height of 13cm, which can be considered as completely inconsiderate of disabled users. Fourth issue was that these people needed safety handle that will enable them to stand up or to be in the standing posture in the living room and bedroom where they spend most of their time. Fifthly, they wanted finishing materials with waterproof functionality as well as replacement of finishing materials and wallpaper which were too old and caused hygiene issues. As these issues represent, current housing for disabled people in the rural area turned out to be poor and risky space rather than the place where difficulty of individual situation can be resolved or their disability can be complemented. Thus it can be determined that now is the time to arrange the solutions for such housing difficulties and to establish customized housing plan to ensure safety and convenience.

• Journal of the Korean Society for information Management
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• v.18 no.1
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• pp.105-126
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• 2001

Serials subscription prices continue to escalate but university library budgets of those have not grown concurrently at the same rate. In fact, library budgets of serials subscription have decreased as a percentage of total library expenditure. Also titles with little or no use should be cancelled to make room for new serials that might be needed to reflect new research interests or changes in curriculum. This study includes overview of the serials cancellation and substitute solutions for subscriptions in university library. Taking into account costs and coverages, availability of cancelled serials through interlibrary loan is high in general. There is a potential for considerable savings by providing access to low-use titles, and that is a combination of commercial document delivery and pay per view based on e-business could be a viable alternative to subscription in many cases.

• Journal of Pharmaceutical Investigation
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• v.23 no.3
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• pp.9-18
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• 1993

Sugar spheres loaded with melatonin (MT) were coated with $Aquacoat^{\circledR}$ to control the release rate of MT over 8 hours. A zero-order release pattern over 8 hours was obtained with 20% coating on 8-10 mesh beads in USP basket dissolution studies. MT in 20% coated beads was quite stable at room temperature with less than 5% MT degraded during 6 months' storage. Dissolution profiles were also unchanged after 6 months. An oral preparation containing MT-loaded uncoated beads for immediate release and 20% coated beads with $Aquacoat^{\circledR}$ for controlled release over 8 hours was evaluated in six human subjects. When total 0.5 mg MT as low dose (immediate release portion of MT, 0.1 mg) was administered to four subjects, average peak plasma MT concentration was reached at about 600 pg/ml and maintained at about 10 pg/ml over 8 hours. Plasma MT concentration-time profiles were similar in shape to computer-simulated profiles. However, maximal plasma MT concentrations were three times greater compared to computer simulated curve. These results suggest that MT dose, ratio of immediate and controlled release MT, and pharmacokinetic parameters selected are adjusted to mimic endogenous MT concentration-time curve. In another study, 0.2 mg MT having 10% of immediate release portion and 80% controlled release portion produced plasma MT concentration-time curve which is more similar to endogenous profiles. A low bioavailability (<20%) may result from extensive first pass metabolism and remaining amounts of MT from controlled beads. A good correlation between plasma MT concentration and urinary excretion rate of 6-sulphatoxymelatonin (6-STMT), a major metabolite of MT was observed. As plasma MT concentration increased, urinary excretion rate of 6-STMT increased concomitantly. The linear relation between plasma MT and urinary excretion rate of 6-STMT was statistically significant. This result suggests that urinary 6-STMT may be used as an index of circadian rhythms of MT in humans.

• Advances in Computational Design
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• v.3 no.4
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• pp.367-384
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• 2018

The consideration of constructability issues at the design stage can lead to improved construction performance with smooth project delivery and savings in time and money. Empirical studies demonstrate the value obtained by integrating construction knowledge with the building design process, and its benefits for owners, contractors and designers. However, it is still a challenge to implement the concept into current design practice. There is a need for a decision support tool to aid designers in reviewing their design constructability, deploying current technological tools, such as BIM. Such tools are beneficial at the conceptual design stage when there is a room to improve the design significantly with less incurred cost. This research investigates how current process- and object-oriented models can be used to assess design constructability. It proposes a BIM-based model using embedded information within the design environment to conduct the assessment. The modelling framework is demonstrated in four key parts; namely, the conceptual design model, the constructability assessment model, the assessment process model and the decision-making phase. Each is associated with a set of components and functions that contribute towards the targeted constructability assessment outcomes. The proposed framework is the first to combine a numerical assessment system and a rule-based system, allowing for both quantitative and qualitative approaches. The modelling framework and its implementation through a prototype are described in this paper. It is believed that this framework is the first to enable users to transfer their construction knowledge and experience directly into a design platform linked to BIM models. The assessment criteria can be customised by the users who can reflect their own constructability preferences into various specialised profiles that can be added to the constructability assessment model. It also allows for the integration of the assessment process with the design phase, facilitating the optimisation of constructability performance from the early design stage.