• The Journal of Korean Physical Therapy
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• 제13권3호
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• pp.719-726
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• 2001

Transdermal drug delivery offers various advantages over conventional drug delivery systems, such as avoidance gastrointestinal degradation and hepatic first-pass effect. encourages patient compliance. and possible sustained release of drugs. However, transdermal transport of drugs is low permeability of the stratum corneum, the superficial layer of the skin. Many physicochemical and biological factors influencing transdermal transport is described together with the corresponding experimental and clinical results. Phonophoresis is medical treatment with drugs introduced into the skin by ultrasound energy. Enhanced drug penetration is through to result from the biophysical alterations of skin structure by ultrasound waves. The frequency used for phonophoresis is usually from 20 kHz to 15MHz. Phonophoresis can be categorized in to three ranges: low-frequency range(below 1 MHz). therapeutic frequency range(1 to 3MHz), and high-frequency range(above 3 MHz). The depth of penetration of ultrasound into skin is inversely proportional to the frequency. Cavitation may cause mechanical stress. temperature elevation, or enhanced chemical reactivity causing drug transport. One theory is that ultrasound affects the permeation of the stratum corneum lipid structure as the limiting step in permeating through the skin. The range of indications for phonophoresis is wide. Aspecific classification of the range of indications is obtained by classification of pathological conditions. The continuous research is needed for many interesting issucs of phonophoretic transdermal delivory in new future.

• 대한안전경영과학회지
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• 제12권2호
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• pp.107-112
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• 2010

Door to door service is a typical method for individual parcel deliveries. In the current delivery information system, a delivery person manually inputs the information of many delivery results, which causes inefficiency and difficulties of tracking deliveries. This study suggests an enhanced delivery information system which has the following two characteristics. Firstly, a tagged RFID(Radio Frequency Identification) transmits the delivery result information to the main server by just collecting RFID at a place of destination. Secondly, with the characteristics of rewritable method, the collected RFID is to be input new information and tagged to other parcels.

• 한국물환경학회지
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• 제29권6호
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• pp.813-824
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• 2013

In this study, sediment pass-through (SPT) from the Sangju Weir and Gumi Weir in the Nakdong River is analyzed numerically using CCHE2D. Sediment delivery is analyzed to predict the sediment discharge rate in the Sangju Weir and Gumi Weir. The sediment discharge from the Sanju Weir is 4,381 tons in the inflow of $3,857m^3/s$, which are 2 year frequency discharge, for 48 hours, and the sediment discharge is 2,766 tons in the inflow of $1,500m^3/s$. The maximum sediment delivery occurs in the immediate downstream of the weir. The sediment discharge from the Gumi Weir is 3,216 tons in the inflow of $5,400m^3/s$, which are 2 year frequency discharge, for 48 hours, and the sediment discharge is 73 tons in the inflow of $3,857m^3/s$. The maximum sediment delivery occurs in the weir. Therefore, the effectiveness of sediment delivery is high in the condition of the 2 year frequency discharge and the gate in the weirs fully are opened.

• 산업공학
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• 제13권3호
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• pp.431-437
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• 2000

This paper refers to the flow of products from supplier to discount retailers(DRs). Discount retailers prefer frequent delivery of small amount because of limited storage space, while suppliers prefer less frequent delivery of larger amount in order to save transportation cost. In this paper we propose a heuristic algorithm to determine the amount of order and the frequency of delivery which decreases the expected length of stockout. We also evaluate various order policies for Vendor Managed Inventory(VMI) system using simulation with real data.

• 대한치과보철학회지
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• 제60권3호
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• pp.239-245
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• 2022

목적: 총의치를 장착한 환자에서 연령, 성별, 총의치를 장착한 악궁, 틀니 보험 적용 여부, 대합치의 종류, 의치 사용 경험, 무치악 기간, 의치상 종류 등에 따라 의치 장착 후 의치를 조정하는 횟수 및 기간에 차이가 있는지를 분석하고자 한다. 대상 및 방법: 5년 간 국민건강보험 일산병원 치과보철과에서 총의치 장착을 시행한 만 65세 이상 환자의 의무기록을 대상으로, 총의치 장착 후 사후 점검의 횟수 및 기간을 평가하였다. 성별, 보험 적용 여부, 총의치를 장착한 악궁, 의치상 종류, 대합치의 종류, 의치 사용 경험, 연령 및 발치 후 의치를 장착하기 전 치유기간에 따른 총의치의 사후 점검 횟수 및 기간의 상관 관계를 분석하기 위해서 5%의 유의수준에서 통계 분석을 시행하였다. 결과: 총 247개의 의치가 포함되었다. 평균 사후 점검 횟수의 중위수는 3회였으며, 사후 점검 기간의 중위수는 36일이었다. 의치를 하악에 장착한 경우가 상악에 장착한 경우보다 사후 점검 횟수가 통계적으로 유의하게 많은 것으로 나타났으며(P = .036) 대합치가 총의치인 경우가 국소의치인 경우에 비해 사후 점검 횟수가 많은 것으로 나타났다(P = .016). 연령, 성별, 보험 적용 여부, 의치 사용 경험, 무치악 기간, 의치상 종류에 따른 사후 점검 횟수는 유의미한 차이가 없었다. 결론: 이번 연구의 한계 내에서, 의치의 조정 횟수는 의치를 장착한 악궁이 하악일 때 및 대합치가 총의치인 경우에서 증가하였다.

• International Journal of Knowledge Content Development & Technology
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• 제14권1호
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• pp.33-52
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• 2024

This study examined the virtual methods of service delivery being deployed by librarians in private universities in Nigeria. The objective of the study was to analyse the virtual methods of service delivery among librarians and determine the predominant method used among the librarians. Survey research design was adopted for the study. Total enumeration technique was adopted for the study. A population of 181 librarians from 45 private universities in Southern Nigeria were involved. Data were gathered, analysed and presented using frequency counts, percentages, mean and standard deviation. The study found that librarians used different virtual methods of service delivery. Library website 157 (90%) and e-mail 132 (76.3%) were the prominent electronic media used by librarians while Facebook 59 (34%) and Whatsapp 57 (32.9%) were the predominant social media platforms applied for service delivery by librarians. Electronic media were more used for latest publications arrival, as well as library education and document delivery services while social media were more used for reference services and selective dissemination of information. In conclusion, virtual methods of service delivery were deployed by librarians in private universities for service delivery. In comparing the virtual methods, librarians used more of electronic media than social media to deliver services to their users. Therefore, electronic media were predominantly used than social media, many of the virtual methods were found to be underutilised while recommendations were proffered.

• Archives of Pharmacal Research
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• 제29권5호
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• pp.412-417
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• 2006

Triamcinolone acetonide (TA) is a corticosteroid that is used in the systemic and topical treatment of many inflammatory diseases. In this study, a phonophoretic drug delivery system was designed to enhance the TA permeability and the influence of ultrasound was examined. In order to establish the transdermal delivery system for TA, a hydrophilic carbopol gel containing TA was prepared after adopting phonophoresis. A permeation study through mouse skin was performed at $37^{\circ}C$ using a Franz diffusion cell, and the ultrasound treatment was carried out for 10 h. The level of TA permeation through the skin was evaluated under various ultrasound conditions including the frequency (1.0, 3.0 MHz), intensity (1.0, $2.5W/cm^2 $), and duty cycle (continuous, pulse mode) using a 0.5% TA gel. The highest permeation was observed under the ultrasound treatment conditions of low frequency, high intensity, and in continuous mode.

• 한국의류산업학회지
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• 제13권4호
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• pp.531-537
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• 2011

Employees of sales departments of apparel makers play an important role in the success of a fashion-related business because they provide service through the direct contact with customers. This research tests several hypothesized relationships between its determinants, such as job satisfaction and customer orientation, along with service delivery level. The subjects in this study were salespeople who worked at fashion stores in Yeosu and Sunchon. To measure the hypotheses, 200 questionnaires were handed out and 185 were collected. 163 questionnaires were used for the analysis, as 22 were found to be invalid. Frequency analysis, factor analysis, reliability analysis, and multiple regression techniques were used after coding and cleaning the data with the software SPSS 18.0. The result of this study are as follow. First, job satisfaction have a positive influence on employee's customer orientation. Second, job satisfaction have an effect on procedural and hospitable service delivery level. Third, it was found that the customer orientation have a significant impact on their procedural and hospitable service delivery level.

• 한국정보과학회:학술대회논문집
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• 한국정보과학회 2002년도 가을 학술발표논문집 Vol.29 No.2 (3)
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• pp.76-78
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• 2002

Multicasting over mobile IP network becomes more important with the increasing needs of supporting multimedia services in mobile network. The IETF has suggested two approaches which are remote subscription and bidirectional tunneling for supporting mobility management in multicasting over mobile IP. But these protocols have problems - the frequent reconstruction of multicast delivery tree, packet less during handoff, convergence problem, and so on. In this paper, we propose to use preconfiguration of multicast delivery tree when mobile host enters the foreign network. It will decrease the frequency of multicast delivery tree reconstruction, and reduce the packet loss during handoff, Also the multicast delivery tree maintained by Keep Alive messages makes the signaling overload of networks diminished.

• Journal of Communications and Networks
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• 제18권3호
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• pp.375-386
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• 2016

Most existing studies on broadcast services in orthogonal frequency division multiplexing (OFDM) systems have focused on how to allocate the transmission power to the subcarriers. However, because a broadcasting system must guarantee quality of service to all users, the performance of the broadcast service dominantly depends on the channel state of the user who has the lowest received signal-to-noise ratio among users. To reduce the effect of the worst user on the system performance, we propose a joint delivery scheme of unicast and broadcast transmissions in OFDM systems with broadcast and unicast best-effort users. In the proposed joint delivery scheme, the BS delivers the broadcast information using both the broadcast and unicast subcarriers at the same time in order to improve the performance of the broadcast service. The object of the proposed scheme is to minimize the outage probability of the broadcast service while maximizing the sum-rate of best-effort users. For the proposed joint delivery scheme, we develop an adaptive power and subcarrier allocation algorithm under the constraint of total transmission power. This paper shows that the optimal power allocation over each subcarrier in the proposed scheme has a multi-level water filling form. Because the power allocation and the subcarrier assignment problems should be jointly solved, we develop an iterative algorithm to find the optimal solution. Numerical results show that the proposed joint delivery scheme with adaptive power and subcarrier allocation outperforms the conventional scheme in terms of the outage probability of the broadcast service and the sum-rate of best-effort users.