• 제목/요약/키워드: Delayed relief

검색결과 29건 처리시간 0.029초

쥐에 대한 레이저 자극시 진통효과 (Laser Photobiostimulation-Induced Hypoalgesia in Rats)

  • 곽현호;김도형;최현희;이충휘
    • 한국전문물리치료학회지
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    • 제5권2호
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    • pp.15-22
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    • 1998
  • Laser photobiostimulation (LPBS) is one of the recent additions to therapeutic procedures used in chronic pain management. Though widely used, a clear understanding of its mechanism of action was not disclosed. In addition, the energy density that produces maximal benefit has not yet been established. The purposes of this study were to determine the effects of LPBS on pain relief in rat and to determine treatment dosage. Eight, 8-week old female, Sprague-Dawley rats were employed. All subjects were assigned to one of four groups: a sham laser group, a 0.4 $J/cm^2$ laser group, a 2.0 $J/cm^2$ laser group, and a 6.0 $J/cm^2$ laser group. Ga-As laser (904 nm wavelength) of three different energy densities (0.4, 2.0, 6.0 $J/cm^2$) was applied on a tail acupuncture point and tail-flick latencies were measured five times pre-and post-treatment as following schedules: 30 minutes, 1 hour. 24 hours. 48 hours, and 7 days later. An increase in pain threshold was demonstrated following LPBS, employing rat tail-flick test. LPBS of 2.0 $J/cm^2$ produced hypoalgesia of rapid onset and short duration (1 hour, 24 hours) while the response to 6.0 $J/cm^2$ was delayed and lasted longer (48 hours, 7 days). LPBS of 0.4 $J/cm^2$ did not produce any hypoalgesia.

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금융권 가계부채 위험증가에 따른 금융감독원 관리방안에 관한 연구 (Study on Management Plan of the Financial Supervisory Service According to Increase of Risk of Household Debts)

  • 이윤홍
    • 한국건설관리학회논문집
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    • 제19권2호
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    • pp.96-106
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    • 2018
  • 정부는 낮은 경제성장률을 극복하기 위해 부동산 활성화정책을 도입하였다. 정부가 추진한 부동산 활성화정책은 규제를 낮춰 대출한도를 높였고, 기준금리도 인하하여 부동산 투자비용을 절감시켰다. 부동산투자를 활성화하기 위해 다주택자에게 양도세 부과를 유예하고, 전매제한도 해지시켰다. 부동산규제 완화는 주택매매 증가와 가격상승으로 이어졌고, 분양아파트는 단기간에 분양이 완료되어 프리미엄이 형성되는 등 부동산시장이 과열양상으로 전환되었다. 이러한 시장분위기는 본인의 소득이 아닌 금융권 '부채의존형'으로 주택을 소유하게 되어 가계대출이 크게 증가되었다. 2017년부터는 가계대출 축소를 위해 부동산대책이 강화되었고, 기준금리도 상승하여 대출 금리도 높아진 만큼, 가계부채 부담은 더욱 증가될 것으로 판단된다. 본 연구논문은 가계부채의 발생 원인과 문제점을 분석하여 금융감독원이 금융권을 효율적으로 관리할 수 있는 방안을 제안하고자 한다.

척골관에서 척골동맥의 주행 이상에 의한 척골신경의 압박 (Compression of the Ulnar Nerve in the Ulnar Tunnel Caused by an Anomalous Pulsatile S-shaped Ulnar Artery)

  • 천남주;김철한;강상규;탁민성
    • Archives of Plastic Surgery
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    • 제36권1호
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    • pp.84-88
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    • 2009
  • Purpose: Compression of the ulnar nerve in the ulnar tunnel is a relatively uncommon condition. Many authors have described several etiologies of ulnar nerve compression. We experienced two cases of ulnar nerve compression in the ulnar tunnel due to an anomalous pulsatile S - shaped ulnar artery. Methods: Case 1: A 51 - year - old man was referred with numbness and paroxysmal tingling sensation along the volar side of the ring and little fingers of his right hand for 6 months. When exploration, the ulnar artery was pulsatile S - shaped and was impinging on the ulnar nerve. To decompress the ulnar nerve, the tortuous ulnar artery was mobilized and translocated radially onto the adjacent fibrous tissue. Case 2: A 41 - year - old man was referred with tingling sensation on the 4 th, 5 th finger of the right hand for 4 months. Sensory nerve conduction velocities of the ulnar nerve was delayed. Preoperative 3D angio CT scan showed an anomalous S - shaped ulnar artery. Same operation was done. Results: The postoperative course was uneventful. After decompression, paroxysmal tingling sensation decreased to less than 1 minute per episode, occurring 1 - 2 times a day. After 4 months, they had no more episodes of numbness and tingling sensation. Examination demonstrated good sensation to pinprick and touch on the ulnar aspect of the hand. Conclusion: We report two cases of ulnar nerve compressive neuropathy that was caused by an anomalous pulsatile S - shaped ulnar artery in the ulnar tunnel. Although this is an unusual cause of ulnar nerve compression, the symptoms will not spontaneously resolve. The prompt relief of compressive neuropathic symptoms following the translocation of the impinging ulnar artery from the affected ulnar nerve onto adjacent tissue proved that the ulnar nerve compression is due to the anomalous vessel.

ADR에서의 지적재산권분쟁 - 중재$\cdot$조정중심으로 - (ADR in IP Dispute)

  • 윤선희
    • 한국중재학회지:중재연구
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    • 제13권1호
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    • pp.125-167
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    • 2003
  • ADR program is designed to solve the problem such as the increase of suits and decision delayed. ADR program has the several significances, decreasing inappropriate cost as time and burden of courts, providing an approachable measure of relief and more efficient tool for settlement of dispute. Particularly ADR program satisfies the needs Intellectual property disputes need specialists that are versed in the subjected problem and, need to be souled quickly in confidence. And parties concerned are not good at the strict judicial procedure in courts, At this point, ADR program holds some advantages over court proceeding for intellectual property disputes. Specialists can be selected as arbitrators or mediator; Cofidentiality may be preserved; Flexibility allows settlement based on mutual commercial interests; Single solution is possible for multiple disputes involving parties from different countries. However, ADR program has not been properly used in. Korea, which is due to not only the lack of understanding the ADR program, but the poor number of filings and settlements. Intermediaries are not professional and also they do not take active hands in disputes. Sometimes, their fairness is asked as peacemakers. Eventually, it is said that this program is not enough to settle international disputes. To activate the ADR program, we can propose the ADR program annexed to court for example. And we can introduce the conciliation and arbitration to disputes in intellectual property. Traditionally arbitration has been a crucial issue in intellectual property disputes. In that intellectual property rights are granted by the local sovereign power, many legal systems in the past maintained the position that the existence, extent, meaning and application of such rights could only be definitively decided by the granting authority or the courts of that country. There is wide recognition that the arbitration of intellectual property is desirable. The law in most of the major countries has been changed in recent years in favor of arbitrability of intellectual property rights. We can also propose ADR on-line.

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Small dose of naloxone as an adjuvant to bupivacaine in intrapleural infiltration after thoracotomy surgery: a prospective, controlled study

  • Amer, Asmaa Fawzy;Omara, Amany Faheem
    • The Korean Journal of Pain
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    • 제32권2호
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    • pp.105-112
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    • 2019
  • Background: Severe pain always develops after thoracotomy; intrapleural regional analgesia is used as a simple, safe technique to control it. This study was performed to evaluate whether a small dose of naloxone with local anesthetics prolongs sensory blockade. Methods: A prospective, randomized double-blinded controlled study was conducted on 60 patients of American Society of Anesthesiologists statuses I and II, aged 18 to 60 years, scheduled for unilateral thoracotomy surgery. After surgery, patients were randomly divided into two groups: through the intrapleural catheter, group B received 30 ml of 0.5% bupivacaine, while group N received 30 ml of 0.5% bupivacaine with 100 ng of naloxone. Postoperative pain was assessed using the visual analog pain scale (VAS). Time for the first request for rescue analgesia, total amount consumed, and incidence of postoperative complications were also recorded. Results: The VAS score significantly decreased in group N, at 6 h and 8 h after operation (P < 0.001 for both). At 12 h after injection, the VAS score increased significantly in group N (P < 0.001). The time for the first request of rescue analgesia was significantly longer in group N compared to group B (P < 0.001). The total amount of morphine consumed was significantly lower in group N than in the bupivacaine group (P < 0.001). Conclusions: Addition of a small dose of naloxone to bupivacaine in intrapleural regional analgesia significantly prolonged pain relief after thoracotomy and delayed the first request for rescue analgesia, without significant adverse effects.

The Treatment Outcome of Elderly Patients with Idiopathic Trigeminal Neuralgia : Micro-Vascular Decompression versus Gamma Knife Radiosurgery

  • Oh, In-Ho;Choi, Seok-Keun;Park, Bong-Jin;Kim, Tae-Sung;Rhee, Bong-Arm;Lim, Young-Jin
    • Journal of Korean Neurosurgical Society
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    • 제44권4호
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    • pp.199-204
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    • 2008
  • Objective : This study was designed to compare the efficacy of micro-vascular decompression (MVD) and Gamma knife radiosurgery (GKRS) for elderly idiopathic trigeminal neuralgia patients by analyzing the clinical outcome. Methods : In the past 10 years, 27 elderly patients were treated with MVD while 18 patients were treated with GKRS (>65-years-old). We reviewed their clinical characteristics and clinical courses after treatment as well as the treatment outcomes. For patients who were treated with MVD, additional treatment methods such as rhizotomy were combined in some areas. In GKRS, we radiated the root entry zone (REZ) with the mean maximum dose of 77.8 (70-84.3) Gy and one 4 mm collimator. Results : The mean age was 68.1 years for MVD, and 71.1 years for GKS group. The average time interval between first presenting symptom and surgery was 84.1 (1-361) months, and 51.4 (1-120) months, respectively. The mean follow-up period after the surgery was 35.9 months for MVD, and 33.1 months for GKRS. According to Pain Intensity Scale, MVD group showed better prognosis with 17 (63%) cases in grade I-II versus 10 (55.6%) cases in GKRS group after the treatment. The pain recurrence rate during follow up did not show much difference with 3 (11.1%) in MVD, and 2 (11.1%) in GKRS. After the treatment, 2 cases of facial numbness, and 1 case each of herpes zoster, cerebrospinal fluid (CSF) leakage, hearing disturbance, and subdural hematoma occurred in MVD Group. In GKRS, there was 1 (5.6%) case of dysesthesia but was not permanent. Three cases were retreated by GKRS but the prognosis was not as good as when the surgery was used as primary treatment, with 1 case of grade I-II, and 1 case of recurrence. The maximal relieve of pain was seen just after surgery in MVD group, and 1 year after treatment in GKRS group. Conclusion : For trigeminal neuralgia patients with advanced age, MVD showed advantages in immediately relieving the pain. However, in overall, GKRS was preferable, despite the delayed pain relief, due to the lower rate of surgical complications that arise owing to the old age.

해사안전감독관 지도·감독 이의신청 제도의 개선방안 연구 (A Study on Improvement Options of Objection Procedure in the Supervision and Guidance of Maritime Safety Supervisors)

  • 이석말
    • 해양환경안전학회지
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    • 제25권6호
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    • pp.708-716
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    • 2019
  • 세월호 사고 이후 내항선 분야의 해사안전관리를 강화하기 위하여 해사안전감독관 제도가 도입되었다. 이들은 선박에 대한 정기 및 수시 지도·감독 중 선박의 시설 분야에서 중대한 결함사항이 발견되면 시정이 완료될 때 까지 선박의 항행을 정지하는 행정처분을 하고 있다. 항행정지명령은 내항선박에 대하여 해사안전감독관이 행사하는 강장 강력한 규제행위의 일종이다. 선박의 안전과 해양환경보호를 위한 해사안전감독관에 의한 내항선박의 지도·감독의 중요성은 아무리 강조해도 지나치지 않을 것이다. 그러나 각 지방해양수산청의 선박에 대한 규제의 정도는 이를 집행하는 사람에 따라 다소의 개인차가 있을 수 있으며, 집행과정에서 개인의 고의 또는 과실이 발생할 수가 있다. 지방해양수산청에 의한 선박의 억류는 선박운항 상의 지체를 가져오기 쉽고, 용선계약의 정지에 의하여 선박의 소유자는 많은 경제적 손실을 입을 수 있다. 그럼에도 불구하고 해사안전법에서는 해사안전감독관에 의한 항행정지명령의 행정처분에 대하여 이의신청과 같은 불복절차를 규정하지 않고 있다. 따라서 이러한 문제점을 극복하기 위하여 지도·감독의 근거가 되는 해사안전법 상에 개인의 고의 또는 과실에 의한 부당한 항행정지 행정처분에 대하여 이의신청을 통한 권리의 구제가 가능하도록 제도를 개선해야 한다.

정상 신기능을 보인 Goodpasture 증후군 1예 (A Case of Goodpasture's Syndrome with Normal Renal Function)

  • 김성경;이진국;주겨레;허성은;김정훈;김영균;이숙영;김승준;김치홍;송소향;박성학;최영진
    • Tuberculosis and Respiratory Diseases
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    • 제59권1호
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    • pp.86-92
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    • 2005
  • Goodpasture's syndrome is a disease that is characterized by hemoptysis, anemia, and glomerulonephritis with renal failure. Goodpasture reported a case of a young man who expired as a result of a pulmonary hemorrhage and glomerulonephritis at the recovery phase after an influenza infection in 1919. In 1958, Stanton et al. described a combined case of these two diseases as Goodpasture's syndrome. Since then, antiglomerular basement membrane antibody(anti-GBM Ab) has been confirmed to play an important role in the mechanism of this syndrome, and it was reported that this syndrome was an autoimmune disease. The triad of alveolar hemorrhage, glomerulonephritis and circulating anti-GBM Ab forms the basis of a diagnosis of Goodpasture's syndrome. When patients are affected by disease, the relief of symptoms can be accomplished by eliminating the anti-GBM Ab from the circulatory system through hemodialysis, plasmapheresis and immunoabsorption. However, the patients usually die from a massive pulmonary hemorrhage when the diagnosis or treatment is delayed. The incidence of Goodpasture's syndrome is common in the western world, but it is extremely rare in Korea with only five cases being reported. In three of these cases, pulmonary hemorrhage and renal failure was the initial manifestation. Therefore, hemodialysis or plasmapheresis were absolutely essential treatments. We report a case of Goodpasture's syndrome in Korea with a normal renal function.

견관절부 외상후 발생된 Shoulder-Hand Syndrome (A Case of the Shoulder-Hand Syndrome Caused by a Crush Injury of the Shoulder)

  • 전재수;이성근;송후빈;김선종;박욱;김성열
    • The Korean Journal of Pain
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    • 제2권2호
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    • pp.155-166
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    • 1989
  • Bonica defined, that reflex sympathetic dystrophy (RSD) may develop pain, vasomotor abnoramalities, delayed functional recovery, and dystrophic changes on an affected area without major neurologic injury following trauma, surgery or one of several diseased states. This 45 year old male patient had been crushed on his left shoulder by a heavily laden rear car, during his job street cleaning about 10 years ago (1978). At first the pain was localizea only to the site of injury, but with time, it spreaded from the shoulder to the elbow and hand, with swelling. X-ray studies in the local clinic, showed no bone abnormalities of the affected site. During about 10 years following the injury, the had recieved several types of treatments such as nonsteroidal analgesics, steroid injections into the glenoidal cavity (10 times), physical therapy, some oriental herb medicines, and acupuncture over a period of 1~3 months annually. His shoulder pain and it's joint dysfunction persisted with recurrent paroxysmal aggrevation because of being mismanaged or neglected for a sufficiently long period these fore permiting progression of the sympathetic imbalance. On July 14 1988 when he visited our clinic. He complained of burning, aching and had a hyperpathic response or hyperesthesia in touch from the shoulder girdle to the elbow and the hand. Also the skin of the affected area was pale, cold, and there was much sweating of the axilla and palm, but no edema. The shoulder girdle was unable to move due to joint pain with marked weakness. We confirmed skin temperatures $5^{\circ}C$ lower than those of the unaffected axilla, elbow and palm of his hand, and his nails were slightly ridged with lateral arching and some were brittle. On X-ray findings of both the shoulder AP & lateral view, the left humerus and joint area showed diffuse post-traumatic osteoporosis and fibrous ankylozing with an osteoarthritis-like appearance. For evaluating the RSD and it's relief of pain, the left cervical sympathetic ganglion was blocked by injecting 0.5% bupivacaine 5 ml with normal saline 5 ml (=SGB). After 15 minutes following the SGB, the clinical efficacy of the block by the patients subjective score of pain intensity (=PSSPI), showed a 50% reduction of his shoulder and arm pain, which was burning in quality, and a hyperpathic response against palpation by the examiner. The skin temperatures of the axilla and palm rose to $4{\sim}5^{\circ}C$ more than those before the SGB. He felt that his left face and upper extremity became warmer than before the SGB, and that he had reduced sweating on his axilla and his palm. Horner's sign was also observed on his face and eyes. But his deep shoulder joint pain was not improved. For the control of the remaining shoulder joint pain, after 45 minutes following the SGB, a somatic sensory block was performed by injecting 0.5% bupivacaine 6 ml mixed with salmon calcitonin, $Tridol^{(R)}$, $Polydyn^{(R)}$ and triamcinolone into the fossa of the acromioclavicular joint region. The clinical effect of the somatic block showed an 80% releif of the deep joint pain by the PSSPI of the joint motion. Both blocks, as the above mentioned, were repeated a total of 28 times respectively, during 6 months, except the steroid was used just 3 times from the start. For maintaining the relieved pain level whilst using both blocks, we prescribed a low dose of clonazepam, prazocin, $Etravil^{(R)}$, codeine, etodolac micronized and antacids over 6 months. The result of the treatments were as follows; 1) The burning, aching and hyperpathic condition which accompanied with vaosmotor and pseudomotor dysfunction, disappeared gradually to almost nothing, within 3 weeks from the starting of the blocks every other day. 2) The joint disability of the affected area was improved little by little within 6 months. 3) The post-traumatic osteoporosis, fibrous ankylosis and marginal sclerosis with a narrowed joint, showed not much improvement on the X-ray findings (on April 25, 1989) 10 months later in the follow-up. 4) Now he has returned to his job as a street cleaner.

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