• Maxillofacial Plastic and Reconstructive Surgery
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• 제35권3호
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• pp.174-177
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• 2013

Bisphosphonate-related osteonecrosis of the jaw (BRONJ) is a disease characterized by jaw necrosis and delayed wound healing in patients who had received bisphosphonates. Buccal fat pad (BFP) can be used as a pedicled flap in the posterior region of the oral cavity. BFP pedicle flap needs simple surgical technique and it shows less donor site morbidity and aesthetic problem than other vascularized flap. BFP pedicled flap was fed by 3 arteries-facial, internal maxillary, and transverse facial artery. Osteomyelitis was generally related with poor blood supply. Thus, rich blood supply of BFP pedicle flap can have a potential advantage to BRONJ patients. In this case report, we presented 3 BRONJ patients treated by BFP pedicle flap after sequestrectomy.

• 대한수의학회지
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• 제52권3호
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• pp.157-162
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• 2012

Corneal injury is very common clinical condition in veterinary medicine and delayed or incomplete corneal healing has the potential of vision loss due to the loss of corneal transparency. For the reconstruction of corneal epithelium, tissue graft and cell transplantation have been prosperously investigated. The purpose of this study was to evaluate the clinical value and short-term safety of application of cultured allogenic mesenchymal stem cells (MSCs) in the treatment of canine experimental corneal defect. Corneal defects were surgically generated in the central corneas of healthy beagle dogs and cultured canine allogenic MSCs were transplanted via subconjunctival injection. Although mean healing time, the rate of epithelial regeneration, and the degree of corneal transparency were not significantly improved after MSC transplantation, significant immune reaction or incompatibility reaction was not detected except transient local irritation. These results propose the possibility of MSC application as a new regenerative medicine in canine ocular disorders.

• Journal of Microbiology and Biotechnology
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• 제15권2호
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• pp.337-345
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• 2005

The degradation of phenanthrene, a model PAH compound, by microorganisms either in the mixed culture or individual strain, isolated from oil-contaminated soil in oil refmery vicinity sites, was examined. The effects of pH, temperature, initial concentration of phenanthrene, and the addition of carbon sources on biodegradation potential were also investigated. Results showed that soil samples collected from four oil refinery sites in Korea had different degrees of PAH contamination and different indigenous phenanthrene-degrading microorganisms. The optimal conditions for phenanthrene biodegradation were determined to be 30$^{circ}C$ and pH 7.0. A significantly positive relationship was observed between the microbial growth and the rate of phenanthrene degradation. However, the phenanthrene biodegradation capability of the mixed culture was not related to the degree of PAH contamination in soil. In low phenanthrene concentration, the growth and biodegradation rates of the mixed cultures did not increase over those of the individual strain, especially IC10. High concentration of phenanthrene inhibited the growth of microbial strains and biodegradation of phenanthrene, but was less inhibitory on the mixed culture. Finally, when non-ionic surfactants such as Brij 30 and Brij 35 were present at the level above critical micelle concentrations (CMCs), phenanthrene degradation was completely inhibited and delayed by the addition of Triton X100 and Triton N101.

• Molecules and Cells
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• 제38권4호
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• pp.362-372
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• 2015

Setdb1, an H3-K9 specific histone methyltransferase, is associated with transcriptional silencing of euchromatic genes through chromatin modification. Functions of Setdb1 during development have been extensively studied in embryonic and mesenchymal stem cells as well as neurogenic progenitor cells. But the role of Sedtdb1 in myogenic differentiation remains unknown. In this study, we report that Setdb1 is required for myogenic potential of C2C12 myoblast cells through maintaining the expressions of MyoD and muscle-specific genes. We find that reduced Setdb1 expression in C2C12 myoblast cells severely delayed differentiation of C2C12 myoblast cells, whereas exogenous Setdb1 expression had little effect on. Gene expression profiling analysis using oligonucleotide microarray and RNA-Seq technologies demonstrated that depletion of Setdb1 results in downregulation of MyoD as well as the components of muscle fiber in proliferating C2C12 cells. In addition, exogenous expression of MyoD reversed transcriptional repression of MyoD promoter-driven luciferase reporter by Setdb1 shRNA and rescued myogenic differentiation of C2C12 myoblast cells depleted of endogenous Setdb1. Taken together, these results provide new insights into how levels of key myogenic regulators are maintained prior to induction of differentiation.

• 대한기계학회논문집B
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• 제29권3호
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• pp.417-423
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• 2005

This paper describes the engine performance of a Homogeneous Charge Compression Ignition(HCCI) engine according to Exhaust Gas Recirculation(EGR), cylinder-to-cylinder, fuel of propane and butane. HCCI engines are being considered as a future alternative for diesel and gasoline engines. HCCI engines have the potential for high efficiency, very low NOx emissions and very low particulate matter(PM). On experimental work, we have done an evaluation of operating conditions in a 4-cylinder compression engine. The engine has been run with propane and butane fuels at a constant speed of 1800rpm. This work is intended to investigate the HCCI operation of the engine in this configuration that has been modified from the base diesel engine. The performance and emissions of the engine are presented. In this paper, the start of combustion(SOC) is defined as the $50{\%}$ point of the peak rate of heat release. SOC is delayed slightly with increasing EGR. As expected, NOx emissions were very low for all EGR range and nbuned HC and CO emission levels were high. CO and HC emissions are lower with using propane than butane as fuels of HCCI engines.

• Fisheries and Aquatic Sciences
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• 제7권1호
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• pp.39-45
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• 2004

Six demographic parameters including life span (LS), maturation time (MT), net reproduction rate (Ro), mean generation length (G), innate capacity for increase $(r_m)$ and finite rate of increase $(\gamma)$ were estimated in the rotifer (Brachionus rotundiformis) cultured at three salinities of 5, 20 and 34 PSU and under a constant temperature of $28^{\circ}C$. The maximum life spans at salinities of 5, 20 and 34 PSU were 17, 12 and 13 days, respectively. The shortest maturation time (24 hr) was recorded at 5 PSU, and the rotifer at 20 PSU showed a most delayed maturation (192 hr). The maximum reproduction rate was 42 offspring per female in rotifer cultured at 5 PSU, while the longest generation length (8 days) was observed at 20 PSU. Maximum and minimum values of $r_m$ (1.56 and 0.46 individual per day) and $(\gamma)$ (6.67 and 1.70 individuals per day) were calculated at 5 and 34 PSU, respectively. Salinity also showed strong effect on correlation of the demographic traits examined. ANOVA revealed significant differences (P<0.05) between demographic parameters of the rotifer at the three salinity condition. Considering the higher values of life span, innate capacity and finite rate of increase, and shortest maturation time at 5 PSU, the rotifer we examined had a higher reproductive potential and longer life span at 5 PSU rather than at 20 or 34 PSU.

• 한국생산제조학회지
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• 제19권4호
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• pp.539-547
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• 2010

Laser shock peening is useful to improve fatigue characteristic of multiple number of metals and alloys. This process induces a compressive residual stress on the metal surface, and when tensile load is applied, growth of crack is delayed and which changes the characteristic of the metal surface. It is an innovative surface treatment technique for strengthening metals. Specimens of SM45C are used in this study. The effect of an inertial tamping layer on the residual stress field using laser shock peening setup and Nd:YAG laser power is evaluated. Residual stress distribution measured by X-ray diffraction. As a result of this study it can be presented that following condition of Nd:YAG laser power and inertial tamping layer parameters, compressive residual stress is generated on the surface of the SM45C. Results to experimental data indicate that laser shock peening has great potential as a means of improving the mechanical performance of the metal surface.

• 대한한방부인과학회지
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• 제30권3호
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• pp.136-145
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• 2017

Objectives: The aim of this study was to report a case of 43 year-old patient, diagnosed with missed abortion who previously failed to do spontaneous gestational sac expulsion in spite of 2 week-expectant-method, eventually succeeded with Traditional Korean Herb Medicine (TKHM) treatment only. Methods: In transabdominal sonography, gestational sac was not present at week 8. Due to the possibility of effect of medication on future pregnancy and post-surgery complications, D&C (Dilation & Curettage) as well as any other treatment was not done. Instead, she presented to our clinic. A combination of 2 main TKHMs was prescribed with 120-150 cc/dose (2 times per day for a week) : Gunggi-tang for helping expulsion of the dead fetus and placenta, and Wooseul-tang for treating retained placenta. Results: On day 6 of TKHM treatment, initiation of placenta expulsion was done. From day 8, hemorrhage started, lasting for 6 days. On day 10, placenta was expelled. On day 13, gestational sac and placenta were completely expelled. No infection, delayed bleeding, or pain was observed. After bleeding stopped, menorrhea started from week 7. Conclusions: This report implies a potential of TKHM as an optional and safe medication for the natural expulsion of conceptus in missed abortion.

• Journal of Trauma and Injury
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• 제32권2호
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• pp.71-79
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• 2019

Purpose: Recent developments in minimally invasive techniques have the potential to reduce surgical morbidity, promote patient recovery, accelerate surgical procedures, and thus improve cost-effectiveness in case management. In this study, we compared the treatment efficacy and results of supraorbital keyhole approach (SOKA) with those of conventional unilateral frontal craniotomy (CUFC) for traumatic intracerebral hemorrhage (TICH) in the frontal lobe. Methods: We analyzed the data of 38 patients who underwent CUFC (n=30) and SOKA (n=8) and retrospectively reviewed their medical records and radiological findings. Furthermore, we tried to identify the best surgical method for such lesions by including patients who underwent burr hole aspiration and drainage (BHAD) (n=9) under local anesthesia due to various circumstances. Results: The difference in the initial Glasgow coma scale score, operative time, and length of hospitalization between the CUFC and SOKA were statistically significant. All radiological features between the two groups including associated skull fracture, amount of pre- and postoperative hematoma, percentage of complete hematoma removal, pre- and postoperative midline shifting of the hematoma, and development of postoperative delayed hematoma were not statistically significant. Our experience of 46 patients with TICH in the frontal lobe with any of the three different surgical methods including BHAD enabled us to obtain valuable findings. Conclusions: Although it is difficult to insist that one particular approach is more useful than the other, we are confident that SOKA will have more advantages over CUFC in carefully selected patients with frontal TICH depending on the surgical experience of a neurosurgeon.

• 한국포장학회지
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• 제27권1호
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• pp.35-40
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• 2021

Calcium hydroxide (CH) reacts with CO2 to produce moisture, and sodium carbonate (SC) reacts with CO2 in the presence of moisture. Using these different characteristics of these two reactants, a CH/SC mixture of CO2 absorber tuned for kimchi ripening to produce CO2 in a flexible package was selected. A ratio of CH:SC (1:2) in highly gas permeable microporous spunbonded film (Tyvek) sachet was found to be appropriate for delayed and consistent CO2 absorption useful for kimchi package. Addition of superabsorbent polymer (SAP) as moisture buffer was helpful for boosting the consistency of CO2 absorption. In a package of 0.5 kg kimchi at 10℃, the sachet consisting of 0.794 g of CH + 2.276 g of SC + 0.4 g of SAP suppressed its volume expansion and maintained a suitable range of CO2 partial pressure (PCO2) steadily inside. These optimal conditions may vary depending on the type and salinity of kimchi, storage and distribution temperature, and the material and area of the absorber sachet. This study showed a potential of mixture CO2 absorber to be tuned for CO2 producing packaged kimchi for the purpose of keeping consistent PCO2 at tolerable volume expansion.