• 한국항행학회논문지
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• 제20권5호
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• pp.475-481
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• 2016

본 논문에서는 상태변수에 시변 지연시간이 있는 선형 이산 구간 시변 시스템의 안정조건을 새롭게 제안한다. 고려한 시스템은 지연 없는 상태변수에 대한 시스템 행렬과 지연 상태변수에 대한 시스템 행렬이 시변 구간 행렬로 표현되며, 지연시간도 구간에 대하여 시변인 특성을 갖는다. 제안된 안정조건은 리아프노프 안정 이론을 이용하여 유도되며, 매우 간단한 부등식의 형태로 표현된다. 본 논문에서는 기존의 시불변 구간 행렬의 안정성 문제를 시변 구간 행렬의 안정성 문제로 확장하고, 기존에 발표된 결과를 포함하는 강력한 안정조건이 유도된다. 이 안정조건의 유도과정에서는 복잡한 선형행렬부등식 혹은 리아프노프 방정식의 상한 해 한계를 구하지 않아도 된다. 또한, 기존의 결과들과의 비교를 통하여 제안된 안정조건이 많은 기존 안정 조건들을 포함할 수 있음을 보인다. 기존 수치예제를 일반적인 형태로 확장하였고 이에 대하여 새로운 안정조건의 확장성과 효용성을 확인한다.

• 한국전문물리치료학회지
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• 제4권1호
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• pp.48-62
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• 1997

Several studies have evaluated the effects of types of relative frequency and delay interval of knowledge of results(KR) on motor skill learning independently. The purpose of this study was to determine more effective types of KR relative frequency and KR delay interval for motor learning. Forty-six healthy subjects (15 female, 31 male) with no previous experience with this experiment participated. The subjects ranged in age from 20 to 29 years (mean=23.9, SD=0.474). All subjects were assigned to one of four groups: a high-instant group, a high-delay group, a low-instant group, and a low-delay group. During the acquisition phase, subjects practiced movements to a target (400 mm) with either a high (83%) or low (33%) KR relative frequency, and with either an instantaneous or delayed (after 8s) KR. Four groups were evaluated on retention (after 3min and 24hr) and transfer (450 mm) tests. The major findings were as follows: (1) there were no between-group differences in acquisition and short-term retention (p>0.05, (2) a low (33%) KR relative frequency during practice was as effective for learning as measured by both long-tenn retention and transfer tests, compared with high (83%) KR practice conditions (p<0.05), (3) delayed (8s) KR enhanced learning as measured by both long-term retention and transfer tests, compared with instantaneous KR practice conditions (p<0.05), and (4) there were no interactions between KR relative frequency and KR delay interval during acquisition, retention, and transfer phases. The results suggest that relatively less frequent and delayed KR are more effective types for motor learning than more frequent and instantaneous KR.

• 대한한방내과학회지
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• 제40권5호
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• pp.957-966
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• 2019

Carbon monoxide intoxication leads to hypoxia, which eventually leads to tissue ischemia. Delayed neuropsychiatric syndrome (DNS) can be a consequence and appears in the form of cognitive impairment and movement disorders after a lucid interval. A 58-year-old Korean male was admitted to our hospital with delayed neuropsychiatric sequelae (DNS) after an 11-day lucid interval following recovery from acute carbon monoxide intoxication. We treated him with herbal medication, acupuncture, electroacupuncture, and moxibustion. The effects were assessed by the activity index and Mini Mental State Examination-Korea (MMSE-K) scores, and by changes in gait disturbance. In this case, the clinical symptoms, including gait disturbance, and the activity index and MMSE-K scores, improved after traditional Korean treatment. The findings of this case report suggest that traditional Korean medicine treatment can be effective for treatment of symptoms of delayed neuropsychiatric sequelae due to CO intoxication.

• 한국항행학회논문지
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• 제27권6호
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• pp.871-876
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• 2023

본 논문에서는 시변 지연 시간이 있는 선형 이산 시변 구간 시스템에 두 가지의 불확실성이 동시에 존재하는 경우에 대하여 안정조건을 다룬다. 구간 시스템은 시스템 행렬들이 구간행렬의 형태로 주어지는 시스템으로 본 논문에서는 이러한 구간 시스템 행렬과 상태변수의 지연 시간이 시변인 특성을 갖는 시스템을 대상으로 한다. 비선형성을 포함하며 그 크기만을 알 수 있는 비구조화된 불확실성과 지연상태변수의 시스템 행렬 불확실성이 동시에 존재하는 경우의 시스템 안정조건을 제안한다. 두가지 종류의 불확실성에 대하여 안정 유지 가능한 크기를 해석적인 수식으로 유도한다. 제안된 안정조건과 안정 보장 크기는 기존의 다양한 선형 이산 시스템에 대한 안정 조건들을 포함할 수 있으며, 시변 지연시간 변동 크기, 불확실성의 크기들과 구간행렬의 범위 등의 값을 모두 조건식에 포함하게 된다. 새로운 안정범위는 수치예제를 통하여 이전의 결과와 비교하며 효용성과 우수성을 검증한다.

• Archives of Plastic Surgery
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• 제41권3호
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• pp.264-270
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• 2014

Background The technique of delayed-immediate breast reconstruction includes immediate insertion of a tissue expander, post-mastectomy radiation, followed by reconstruction. The aesthetic benefits of delayed-immediate reconstruction compared to delayed reconstruction are postulated but remain unproven. The purpose of this study was to compare aesthetic outcomes in patients following delayed and delayed-immediate autologous breast reconstruction. Methods A retrospective analysis was performed of all patients who underwent delayed or delayed-immediate autologous breast reconstruction by the senior author from 2005 to 2011. Postoperative photographs were used to evaluate aesthetic outcomes: skin quality, scar formation, superior pole contour, inferior pole contour, and overall aesthetic outcome. Ten non-biased reviewers assessed outcomes using a 5-point Likert scale. Fisher's Exact and Wilcoxon-Mann-Whitney tests were used for comparative analysis. Results Patient age and body mass index were similar between delayed (n=20) and delayed-immediate (n=20) cohorts (P>0.05). Skin and scar quality was rated significantly higher in the delayed-immediate cohort (3.74 vs. 3.05, P<0.001 and 3.41 vs. 2.79, P<0.001; respectively). Assessment of contour-related parameters, superior pole and inferior pole, found significantly improved outcomes in the delayed-immediate cohort (3.67 vs. 2.96, P<0.001 and 3.84 vs. 3.06, P<0.001; respectively). Delayed-immediate breast reconstruction had a significantly higher overall score compared to delayed breast reconstructions (3.84 vs. 2.94, P<0.001). Smoking and the time interval from radiation to reconstruction were found to affect aesthetic outcomes (P<0.05). Conclusions Preservation of native mastectomy skin may allow for improved skin/scar quality, breast contour, and overall aesthetic outcomes following a delayed-immediate reconstructive algorithm as compared to delayed breast reconstruction.

• Journal of Preventive Medicine and Public Health
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• 제22권2호
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• pp.259-267
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• 1989

The objective of this study was to analyze the influence of the hospital and insurer in causing delayed reimbursement of medical insurance benefits. We analyzed major variables at three different sized hospitals to examine the effect of the hospital and insurer using the two-way ANOVA method. The results were as follows: 1. The time interval between claim by hospitals and payment of the benefit was statistically different according to hospital in both admission and outpatient care. 2. The time needed by the insurer for investigating the claims was statistically different according to hospital and insurer in both admission and outpatient care. There was interaction between the hospital and insurer factors in outpatient care. 3. Although there was interaction between the hospital and insurer factors in admission care, the time interval between claim and payment was statistically different. In outpatient care, the payment interval between claim and payment was also statistically different according to the hospital and insurer.

• 대한응급의학회지
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• 제29권5호
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• pp.519-528
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• 2018

Objective: Delayed neuropsychiatric sequelae (DNS) following carbon monoxide (CO) poisoning, which may result from a demyelinating leukoencephalopathy, is a disease with a poor prognosis. This study examined the factors affecting the long-term prognosis of DNS and the efficacy of hyperbaric oxygen therapy (HBOT) in patients with DNS. Methods: This retrospective study included 84 patients with DNS following CO poisoning from January 2013 to June 2016. HBOT was given to 24 patients. The patients were divided into an improvement group and non-improvement group based on their clinical condition on a telephone interview at intervals between 3 months and 3 years after the onset of DNS. The improvement group was defined as having Cerebral Performance Category (CPC) scores in their daily life that improve to 1 or 2 grade. Results: Of the 594 patients, DNS were found in 18.2%, and 70.2% (59 of 84) of the patients with DNS improved. The prognostic factors for the improvement of DNS were an age of 45 years or less (odds ratio [OR], 12.068; 95% confidence interval [CI], 2.393-60.858; P<0.005), CPC score of 1 or 2 group at the time of DNS onset (OR, 12.361; 95% CI, 3.161-48.330; P<0.005), and a lucid interval longer than 20 days (OR, 5.164; 95% CI, 1.393-19.141; P<0.01). HBOT was not associated with the improvement of DNS in CO poisoning (OR, 0.467; 95% CI, 0.172-1.269; P>0.1). Conclusion: Patients aged less than 45 years, low grade CPC score of 1 and 2, and lucid interval longer than 20 days are more likely to have a good prognosis. On the other hand, HBOT failed to produce a benefit for DNS patients.

• 한국간담췌외과학회지
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• 제28권1호
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• pp.1-13
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• 2024

Hepatocellular carcinoma (HCC) is the sixth most diagnosed cancer worldwide. Healthcare resource constraints may predispose treatment delays. We aim to review existing literature on whether delayed treatment results in worse outcomes in HCC. PubMed, Embase, The Cochrane Library, and Scopus were systematically searched from inception till December 2022. Primary outcomes were overall survival (OS) and disease-free survival (DFS). Secondary outcomes included post-treatment mortality, readmission rates, and complications. Fourteen studies with a total of 135,389 patients (delayed n = 25,516, no delay n = 109,873) were included. Age, incidence of male patients, Child-Pugh B cirrhosis, and Barcelona Clinic Liver Cancer Stage 0/A HCC were comparable between delayed and no delay groups. Tumor size was significantly smaller in delayed versus no delay group (mean difference, -0.70 cm; 95% confidence interval [CI]: -1.14, 0.26; p = 0.002). More patients received radiofrequency ablation in delayed versus no delay group (OR, 1.22; 95% CI: 1.16, 1.27; p < 0.0001). OS was comparable between delayed and no delay in HCC treatment (hazard ratio [HR], 1.13; 95% CI: 0.99, 1.29; p = 0.07). Comparable DFS between delayed and no delay groups (HR, 0.99; 95% CI: 0.75, 1.30; p = 0.95) was observed. Subgroup analysis of studies that defined treatment delay as > 90 days showed comparable OS in the delayed group (HR, 1.04; 95% CI: 0.93, 1.16; p = 0.51). OS and DFS for delayed treatment were non-inferior compared to no delay, but might be due to better tumor biology/smaller tumor size in the delayed group.

• Journal of Trauma and Injury
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• 제22권2호
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• pp.212-217
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• 2009

Purpose: To analyze delayed diagnosis, we collected date on pediatric and adolescent patients who had been admitted to the Emergency Department with injuries due to minor trauma Methods: We retrospectively analyzed the age distribution, trauma mechanism, time interval for each affected body region at delayed diagnosis, hospital stay, and outcome for 161 pediatric and adolescent patients who had been admitted to the Emergent Department of Gachon University Gil Hospital from January 2006 to September 2008. Results: The incidence of delayed diagnosis in pediatric and adolescent trauma was 11.8% in our retrospective review of 161 pediatric and adolescent patients. Lengths of hospitalization were longer in patients with delayed diagnosis (p<0.05). Patients with delayed diagnosis were more often transferred to other hospitals than patients with non-delayed diagnosis (p<0.05). The time intervals for each different affected body regions at delayed diagnosis were significantly different, but the hospital stays were not. There were no statistical significance to age on affected body region. Conclusion: From this study, we found that admission result and hospital stay were statistically significant differences between the delayed-diagnosis patient group and the non-delayed-diagnosis patient group. Finally, we must follow up pediatric and adolescent patients with minor trauma, closely considering missed injuries.

• 한국수정란이식학회지
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• 제24권2호
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• pp.127-130
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• 2009

The purpose of this study was to determine the effect of cows parity and calving seasons on the subsequent reproductive performance of the herd of Korean native cows raised under the same condition. With the parity of the cows ranged 1 to 4 (mean: 1.9), significant associations were found between parity and calving interval (p<0.05). Calving interval of the primiparous cows group was 395.0 ${\pm}$ 16.5 days, which was the longest calving interval among the four groups. On the other hand, calving interval of the second parity group was 333.7 ${\pm}$ 3.6 days. The primiparous cows had tendencies that long interval from calving to conception and small number of service per conception relatively when compared with the multiparous cows. In the case of calving season, the interval from calving to first service was short in summer and winter relatively. The interval from calving to conception in summer was the shortest in four seasons. The number of service per conception was larger in spring and winter and smaller in summer and autumn. Calving in spring showed delayed reproductive performance and calving in summer showed desirable reproductive performance.