• 제목/요약/키워드: Delayed injection

검색결과 215건 처리시간 0.022초

젖소 공란우 과배란 처리 후 난소주기 재개에 관한 연구 (Resumption of Ovarian Cyclicity after Superovulation Treatment to Donor Cow in Holstein Donor Cows)

  • 손준규;백광수;윤호백;임현주;권응기;조상래;정연섭;김선규;최창용
    • Reproductive and Developmental Biology
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    • 제37권1호
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    • pp.35-40
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    • 2013
  • The objective of this study was to investigate the effects of abnormal ovarian cycles after superovulation treatment of Holstein Donor Cows. CIDRs were inserted into the vaginas of twenty two head of Holstein cows, regardless of estrous cycle. Superovulation was induced using folliclar stimulating hormone (FSH). For artificial insemination, donor cows were injected with $PGF_2{\alpha}$ and estrus was checked about 48 hours after the injection. Then they were treated with 4 straws of semen 3 times, with 12-hour intervals. Embryos were collected by a non-surgical method 7 days after the first artificial insemination. The cows were considered to have resumed ovarian cyclicity on the day of ovulation if followed by regular ovarian cycles. Seventy two point seven percentage of the cows(16/22) had normal resumption of ovarian cyclicity(resumption within 40 days after superovulation), and 27.3%(6/22) had delayed resumption(resumption did not occur until>40 days after superovulation). Delayed resumption Type II(first ovulation did not occur until ${\geq}40$ days after superovulation, i.e. delayed first ovulation 13.6%) were the most common types of delayed resumptions. The mean numbers of total ova from < 10 and $10{\leq}$ of corpora lutea(CL) was $7.8{\pm}1.8$ and $12.7{\pm}2.7$, respectively. The number of transferable embryos differed between < 10 and $10{\leq}$ CL was $5.4{\pm}1.3$ and $8.1{\pm}3.4$, respectively. Four point five percentage of the cows(1/22) did not resumption their ovarian cyclicity until 60 days after superovulation treatment. Diverse researches on the superovulation treatment method that is suitable for high-producing Holstein donor cows would contribute to preventing ovarian cyclicity disorder, as well as to the early multiplication of cows with superior genes by increasing the utilization value of donor cows.

Paresthesia diagnosed using cone-beam computed tomography: a case report

  • Kumar, Umesh;Kaur, Charan Kamal;Vashisht, Ruchi;Rattan, Vidya
    • Journal of Dental Anesthesia and Pain Medicine
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    • 제20권2호
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    • pp.95-99
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    • 2020
  • Various dental procedures, such as injection administration, surgical treatment, and endodontic treatment, can cause injury to the nerves. The most commonly injured nerves are the inferior alveolar and lingual nerves. This can manifest as altered sensation to the area of innervation of the injured nerve, such as the lower lip, chin, teeth, tongue, and mucosa. Altered sensations or loss of sensation are relatively infrequent complications in daily dental practice. Here, we report an uncommon case of altered sensation in the midfacial region caused by an endodontic procedure and discuss the need to consider local dental causes in the differential diagnosis of numbness in the facial region.

원유 저장용 지하공동의 건설중 점토 그라우팅에 의한 지하수 제어 (Countrol of Groundwater by Clay Grouting in Undergroun Excavation of Oil Storage Caverns)

  • 김치환;박창우;이석천
    • 터널과지하공간
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    • 제3권1호
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    • pp.24-32
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    • 1993
  • Groundwater movement is one of the most important elements in the construction and management of underground oil storage cavern. To control the groundwater flow, grouting is run in parallel with water curtains. But as traditional grouting is conducted within cavern before and after excavation, the effect of grouting is delayed and the injection sphere is limited in the rock mass. Therefore, it is desirable to introduce a more extensive and effective grouting. This article is to present the caly grouting, which was the first to be carried out in the construction of underground caverns for oil storage in Japan. After conducting the clay grouting, the effect was confirmed by ground water level and infiltration quantity to the caverns.

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교통환경 정온화를 위한 도로 소음의 측정 및 ANC시스템에의 적용 특성 고찰 (A Study on the Characteristics of Applicability in the Active Noise Cancellation System and Measurement of the Road Noise for Traffic Calming)

  • 문학룡;손진근
    • 전기학회논문지P
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    • 제62권3호
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    • pp.111-116
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    • 2013
  • Noise problem that occurs on the road is raising a lot of problems in the economic, social and environmental aspects. The objective of this paper is to propose ANC(active noise cancellation)-based road traffic noise reduction algorithm-model which can reduce noise by generating frequency opposed to noise sources to improve and complement the problem that existing physical form of a noise barrier. In this paper, we measured the noise characteristic from collection of two difference car noise also ANC simulation has been performed by using road traffic noises input. In order to compare the control performance, we performed noise reduction simulation of ANC by filtered-X LMS algorithm and delayed control signal injection. As a result of this simulation, we confirmed that convergence performance and noise decrease effect to the filtered-X LMS algorithm by inputting the road traffic noise.

마우스에 있어서 카드뮴의 면역독성에 미치는 인삼 석유 Ether분획의 영향(II) (Effect of Ginseng petroleum Ether Fraction on the Immunotoxicity of Cadmium in Mice (II))

  • 안영근;김정훈;이상근;황갑수
    • Environmental Analysis Health and Toxicology
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    • 제3권3_4호
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    • pp.1-8
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    • 1988
  • Experiment was performed to investigate the immunotoxicity of cadmium administered orally and the effect of ginseng petroleum ether fraction on it. Mice were given 3, 30, or 300 ppm cadmium as cadmium chloride orally in the drinking water and injection of ginseng petroleum ether fraction intraperitoneally for 4 weeks. Mice were sensitized and challenged u'ith sheep red blood cells (5-HBC). Immune response was evaluated by delayed type hypersensitivity (DTH), Rosette forming cell (RFC), phagocyte activity, and natural killer cell activity (NK cell activity). In the present study, cadmium suppressed the cellular immunity, It also depressed phagocyte activity very significantly in all cadmium-administered groups, NK cell activity in the cadmium-300 ppm administered group. Ginseng petroleum ether fraction showed restoring effect on the decrease in RFC by cadmium-administration. Remarkably, it showed very significant restoring effect on the depression of phagocyte activity induced by cadmium-administration. From this result, we suppose that the anti-tumor effect of ginseng ether or petroleum ether extract, which has been reported by some other researchers, is mainly due to the increase of phagocyte activity by it's administration.

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Protection by native edible plant extract MK-104 against kainate-induced neurotoxicity in mouse brain

  • Oh, Sang-Hee;Kim, Mee-Ree
    • 한국식품저장유통학회:학술대회논문집
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    • 한국식품저장유통학회 2003년도 춘계총회 및 제22차 학술발표회
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    • pp.109.2-110
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    • 2003
  • The neuroprotective effect of solvent fraction of native edible plant MK-104 in the mice administered with kainate was evaluated using behavioral sign, neuronal injuries and biomarkers of oxidative stress. Mice, ICR male, were administered with the BFME through a gavage for 4 days consecutively, and on the 3rd day, kainate (450 mg/kg) was i.p. administered. The fraction(400 mg/kg) delayed the onset time of neurobehavioral change (p<0.01), reduced the severity of convulsion and lethality (p<0.05), and restored the level of GSH and lipid peroxidation in brain to control value. A similar protective action was also expressed by fraction-I (200 mg/kg), which showed a prominent protection against the neuronal damage in hippocampal CA1 and CA2 regions (p<0.01) caused by kainate injection. of TBARS value. Based on these results, BFME-I is suggested to contain a functional agent to prevent against oxidative stress in the brain of mice.

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Ricin의 독성이 생쥐의 간. 비장, 흉성, 폐 및 심장에 미치는 영향에 관한 조직학적 연구 (Histological effects of ricin on liver, spleen, thymus, lung and heart of mouse)

  • 유명희;김지혜;김재호
    • 생명과학회지
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    • 제11권2호
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    • pp.111-120
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    • 2001
  • The pathological aspects of purified ricin from the seeds of the castor oil plant, Ricinus communis, were examined, using light and transmission electron microscopy. ICR mice were exposed to ricin by peritoneal injection with 100 ng/1 $m\ell$ PBS(pH 7.0) mouse and histological observations on the liver, spleen, thymus, lung and heart were carried out at intervals up to 48 h after exposures. All the organs examined were damaged by ricin. Among the organs, the spleen and thymus; immune organs were the most sensitive to ricin, whereas the effect delayed in the liver, lung and heart. Furthermore, the immune cells in each organ were the most sensitive to ricin. Accordingly, the effect of ricin on the organs seems to be affected by the immune cells existed in each organ, In each organ, the immune cells showed apoptotic changes, while the capillary endothelial and parenchymal cells showed necrotic changes.

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Tc-99m HMPAO 표지 백혈구스캔상 대퇴 절주에서 우연히 발견된 가성동맥류 (Incidental Detection of a Pseudoaneurysm at an Amputation Stump in a Tc-99m HMPAO labeled Leukocyte Scan)

  • 손명희;정환정;임석태
    • Nuclear Medicine and Molecular Imaging
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    • 제41권4호
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    • pp.337-338
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    • 2007
  • A 20-year-old man underwent a Tc-99m HMPAO labeled leukocyte scan for the evaluation of an infection at the stump of an AK amputation, which was conducted due to an open communicated fracture of the left lower leg. Blood-flow and blood-pool images demonstrated a pseudoaneurysm with a focus of intense activity medial to the stump, and centered within a large photopenic defect by surrounding hematoma. Delayed image obtained at 3 hours post-injection showed persistent intense and slight increased activity, Contrast angiography confirmed the presence of a pseudoaneurysm arising from a branch of the left superficial femoral artery.

Prostaglandin $F_{2\alpha}$, GTH 및 Antibiotics의 투여가 Repeat breeder의 치료에 미치는 영향 (Studies on Effects of the Administration of $PGF_{2\alpha}$ GTH and Antibiotics in Repeat Breeders)

  • 정병현
    • 한국가축번식학회지
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    • 제9권1호
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    • pp.66-71
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    • 1985
  • After the induction of estrus by the PGFF2$\alpha$-GTH combination on the 118 repeat breeder cow during of 6-13 days of the estrus cycle, the effects of GTH, antibiotics, antibiotics-GTH combination were compared. The results of this study, the following conclusion were obtained: 1. The rate of estrus was reduced the administration of GTH before the administration of PGF2$\alpha$. 2. The rate of ovulation delayed was 24.6% in the group with the administration GTH, but 34.1% without the administration GTH. Duration of ovulation was shortened by GTH. 3. The impregnation induction by the administration of PGF2$\alpha$, PGF2$\alpha$-antibiotics, PGF2$\alpha$-GTH-antibiotics were 41.7%, 69.5%, 55.6% and 80.8% respectively injection in the uterus was more effective than the administration. Before or after the A.I., the above combination was most effective. 4. In antibiotics sensitivity test in vitro of the intravagina bacteria, 5.0%, 12.7% and 60.0% of bacteria were sensitive to Penicilline, Streptomycin and Gentamicin respectively.

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Changes in the Central Dopaminergic Systems in the Streptozotocin-induced Diabetic Rats

  • Lim, D.K.;Lee, K.M.;Ho, I.K.
    • Archives of Pharmacal Research
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    • 제17권6호
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    • pp.398-404
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    • 1994
  • The behavioral response, depamine metabolism, and characteristics of dopamine subtypes after developing the hyperlycemia were studied in the striata of rats. In animals developed hyperglycemia, the on-set duration of cataleptic behavior responded to SCH 23390 injection was delayed abd shortened, respectively. However, the cataleptic response to spiperone occurred significantly earlier in on-set and prolonged in duration. Dopamine metabolites, dihydroxyphenylacetic acid (DDPAC) and homovanillic acid (HVA), were significantly reduced in teh striata of hyeprglycemic rats. However, level of DA was significantly increased. It is noted that the ratios of DOPAC and HVA to DA were decreased, suggesting decreased tumover of DA. The affinity of striatal D-1 receptors was significantly increased without changes in the number of binding sites, while the maximum binding number of D-2 recptors was significantly increased without affecting its affinity in the diabetic rats. These results indicate that the dopaminergic activity in striatia was altered in hyperglycemic rats. Furthermore, it suggests that the upregulation of dopamine receptors might be due to the decreased dopamine matabolism.

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