• 제목/요약/키워드: Delayed injection

검색결과 215건 처리시간 0.027초

일측성 성대마비 환자에서 Artecoll을 이용한 성대주입술의 효과 및 안전성 (The Effect of Artecoll Injection for the Patients with Unilateral Vocal Cord Paralysis)

  • 오재원;이승원;김민범;윤영선;김관민;손영익
    • 대한후두음성언어의학회지
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    • 제16권2호
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    • pp.129-134
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    • 2005
  • Background and Objectives : Artecoll(R) is an injectable soft tissue filler, which is a suspension of polymethylmethacrylate microspheres in $3.5\%$ bovine collagen solution. The authors aimed to determine the clinical of Artecoll of Artecoll(R) as an injection material into the vocal fold to correct the glottal insufficiency caused by unilateral vocal cord paralysis. Materials and Methods : Forty-one consecutive patients with unilateral vocal cord paralysis received percutaneous Artecoll injections under local anesthesia. Acoustic, aerodynamic and stroboscopic analyses were prospectively provided before, 1 week and 3 months after injection. Perceptual GRBAS grading by speech language pathologists and subjective ratings of the hoarseness and aspiration by the patients were also obtained. Results : Aerodynamic parameter(maximal phonation time) were significantly improved after the injection (p<0.05). Acoustic parameters (jitter and shimmer) were improved at the 3rd month follow-up. GRBAS uading and patients own subjective scaling of hoarseness and aspiration also showed significant improvement (p<0.05). Early or delayed significant side effects were not observed. Conclusion : Vocal fold injection with Artecoll is a convenient, safe and useful method of temporarily correcting the glottal insufficiency. Further long-term follow-up studies will answer the usefulness and safety of the Artecoll injection laryngoplasty.

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CAPA를 활용한 적용사례 및 개선대책 (Case studies using CAPA to eliminate problems)

  • 이영창;여동구;구본흥
    • 한국소성가공학회:학술대회논문집
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    • 한국소성가공학회 2002년도 금형가공 심포지엄
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    • pp.95-102
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    • 2002
  • With recent trends leaning towards product miniaturization, the advent of new material and speedy delivery times, old style conventional trial-and-error methods have been only serving to weaken corporate competitiveness. Reliant on tiny increments of time-consuming experience, this antiquated approach begets a delayed delivery of product development, cost loss and quality depreciation. To solve such problems, the Dedicated Injection Molding CAPA (Computer Aided Plastics Application) performs a preliminary examination on problems rising from every stage of creation - from appropriate material selection and mold design to mass production - through a computer system. Thus, it determines the optimum design variables and process conditions while diagnosing and solving defective molds.

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마황의 면역작용에 미치는 효과 (Effect of Ephedrae Herba on the Immune Response in Mice)

  • 김태희;양기숙;황은진;박성배
    • 생약학회지
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    • 제22권3호
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    • pp.183-191
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    • 1991
  • The effects of Ephedrae herba on cellular and humoral immune responses were investigated in mice. Group A and B of mice received intraperitoneal injection of methanol extracts, ether fraction(E), petroleum ether fraction(PE), ethyl acetate fraction(EA) and water fraction(W) for 5 days or 10 days before sensitization. The other group received i.p. injection of ephedrine (Ep) or pseudoephedrine $({\psi}\;Ep)$ for 1 day prior to sensitization. The change of body and spleen weights showed a tendency of decreasing but that of thymus showed increasing. Ear swelling was maximum at 48 hours after challenge and was significantly decreased in the groups treated with EA, W, Ep, and ${\psi}\;Ep$. HA titer was enhanced in EA, W and EP treated groups, HE titer being significantly decreased.

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Involvement of Vascular NAD(P)H Oxidase-derived Superoxide in Cerebral Vasospasm after Subarachnoid Hemorrhage in Rats

  • Kim, Dong-Eun;Kim, Chi-Dae
    • The Korean Journal of Physiology and Pharmacology
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    • 제6권1호
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    • pp.15-19
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    • 2002
  • The role of vascular NAD(P)H oxidase in subarachnoid hemorrhage (SAH)-induced vasospasm in the basilar artery was examined in a rat model. Arterial vasospasm characterized by increased wall thickness and decreased lumen size was observed at 5 to 7 days after $2^{nd}$ injection of blood into cisterna magna, and these changes were significantly ameliorated by pretreatment of diphenyleneiodonium $(DPI,\;25\;{\mu}l\;of\;100\;{\mu}M),$ an inhibitor of NAD(P)H oxidase. To determine the time course of changes in the vascular NAD(P)H oxidase activity, cerebral vasculature was isolated at different time intervals from 12 hrs to 14 days after injection of autologous blood. At 24 hrs after the second injection of blood, the NAD(P)H oxidase activity was markedly increased with an enhanced membrane translocation of p47phox, but by 48 hours both the enzyme activity and p47phox translocation regained normal values, and were remained unchanged up to 14 days after SAH. However, no significant changes in the expression of p22phox mRNA was observed throughout the experiments. These findings suggest that the activation of NAD(P)H oxidase by which assembly of the oxidase components enhanced and subsequent production of superoxide in the early stages of SAH might contribute to the delayed cerebral vasospasm in SAH rats.

직접분사 CNG 연료의 분사특성에 관한 연구 (A Study on the Injection Characteristics of Direct Injection CNG Fuel)

  • 이성욱;;;김인구;강호인
    • 한국수소및신에너지학회논문집
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    • 제25권6호
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    • pp.643-647
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    • 2014
  • Two types of fuel supply method ar used in CNG vehicles. One is premixed ignition and the other is gas-jet ignition. In premixed ignition, the fuel is introduced with intake air so that homogeneous air-fuel mixture may form. The ignitability of this method depends on the global equivalence ratio. In gas-jet ignition, CNG is introduced directly into the engine combustion chamber. The overall mixture is stratified by retarded fuel injection. In this study, a visualization technique was employed to obtain fundamental properties regarding overall mixture formation of direct injected CNG fuel inside a constant volume chamber. Jet angles, penetrations and projected jet area with respect to ambient pressure are investigated. The penetration decreases apparently and the time reaching the CVC wall was delayed as the chamber pressure increases. This is caused by the higher inertia of the fluid elements that the injected fluid must accelerate and push aside. It is same to liquid fuel such as diesel and gasoline, but this phenomenon is far more prominent for the gaseous fuel.

Successful Treatment of Rectus Femoris Calcification with Ultrasound-guided Injection: A Case Report

  • Hong, Myong Joo;Kim, Yeon Dong;Park, Jeong Ki;Kang, Tai Ug
    • The Korean Journal of Pain
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    • 제28권1호
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    • pp.52-56
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    • 2015
  • Painful periarticular calcification most commonly occurs within the rotator cuff of the shoulder and rarely around the elbow, hip, foot, and neck. As acute inflammatory reaction develops, severe pain, exquisite tenderness, local swelling, and limitation of motion with pain occur. In case of calcific tendinitis of the shoulder, it can be easily diagnosed according to the symptoms and with x-ray. However, in lesions of the hip, as it is a rare location and usually involves pain in the posterolateral aspect of the thigh, which can simulate radicular pain from a lumbar intervertebral disc, it could be difficult to diagnose. Hence, physicians usually focus on lumbar lesions; therefore, misdiagnosis is common and leads to a delayed management. Here, we report the case of a 30-year-old female patient with calcific tendinitis of the rectus femoris that was successfully managed with ultrasound-guided steroid injection. This study offers knowledge about the rectus femoris calcification.

금형온도 능동제어 시스템 적용을 위한 고 내구성 마이크로 히터의 설계 및 제작 (Design and Fabrication of Durable Micro Heater for Intelligent Mold System)

  • 노철용;김영민;최용;강신일
    • 정보저장시스템학회:학술대회논문집
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    • 정보저장시스템학회 2005년도 추계학술대회 논문집
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    • pp.26-30
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    • 2005
  • Stamper surface temperature is very critical in replicating the high density optical disc substrates using injection molding as the pit or land/groove patterns on the optical disc substrate have decreased due to the rapid increase of areal density. During the filling stage, the polymer melt in the vicinity of the stamper surfaces rapidly solidifies and the solidified layer generated during polymer filling greatly deteriorates transcribability and fluidity of polymer melt. To improve transcribability and fluidity of polymer melt, stamper surface temperature should be controlled such that the growth of the solidified layer is delayed during the filling stage. In this study, the effect of heating on replication process was simulated numerically. Then, an injection mold equipped with instant active heating system was designed and constructed to raise the stamper surface temperature over the glass transition temperature during filling stage of the injection molding. Also, the closed loop controller using the Kalman filter and the linear quadratic Gaussian regulator was designed. As a result, the stamper surface temperature was controlled according to the desired reference stamper surface temperature.

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SELF-PULSATION CHARACTERISTICS OF A SWIRL COAXIAL INJECTOR WITH VARIOUS INJECTION AND GEOMETRIC CONDITIONS

  • Im, Ji-Hyuk;Kim, Dong-Jun;Yoon, Young-Bin;Bazarov, V.
    • 한국분무공학회지
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    • 제10권3호
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    • pp.29-37
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    • 2005
  • The spray and acoustic characteristics of a gas/liquid swirl coaxial injector are studied experimentally. The self-pulsation is defined as a pressure and flow rate oscillations by a time-delayed feedback between liquid and gas phase. Self-pulsation has strong influences on atomization and mixing processes and accompanies painful screams. So. the spray and acoustic characteristics are investigated. Spray patterns are observed by shadow photography technique in order to determine the onset of self-pulsation. And self-pulsation boundary with Injection conditions and recess length is get. To measure the frequency of the spray oscillation. oscillation of the laser intensity which passes through spray is analyzed by Fast Fourier Transform. For acoustic tests, a PULSE System was used. Acoustic characteristics of a swirl coaxial injector are investigated according to the injection conditions. such as the pressure drop or the liquid and gas phase. and injector geometries. such as recess length and gap size between the inner and outer injector. Front the experimental results. the increase of recess length leads to the rapid increase of the sound pressure level. And as the pressure drop of the liquid phase increases. the frequency of the self?pulsation shifts to the higher frequency. The frequency of spray oscillations is the same as that of the acoustic fields by self-pulsation.

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금형온도 능동제어 시스템 적용을 위한 고 내구성 마이크로 히터의 설계 및 제작 (Design and Fabrication of Durable Micro Heater for Intelligent Mold System)

  • 노철용;김영민;최용;강신일
    • 정보저장시스템학회논문집
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    • 제2권2호
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    • pp.100-104
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    • 2006
  • Stamper surface temperature is very critical in replicating the high density optical disc substrates using injection molding as the pit or land/groove patterns on the optical disc substrate have decreased due to the rapid increase of areal density. During the filling stage, the polymer melt in the vicinity of the stamper surfaces rapidly solidifies and the solidified layer generated during polymer filling greatly deteriorates transcribability and fluidity of polymer melt. To improve transcribability and fluidity of polymer melt, stamper surface temperature should be controlled such that the growth of the solidified layer is delayed during the filling stage. In this study, the effect of heating on replication process was simulated numerically. Then, an injection mold equipped with instant active heating system was designed and constructed to raise the stamper surface temperature over the glass transition temperature during filling stage of the injection molding. Also, the closed loop controller using the Kalman filter and the linear quadratic Gaussian regulator was designed. As a result. the stamper surface temperature was controlled according to the desired reference stamper surface temperature.

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육불화황 기체의 주입단계에 따른 탄소코일 기하구조의 제약 (Effect of Injection Stage of SF6 Gas Incorporation on the Limitation of Carbon Coils Geometries)

  • 김성훈
    • 한국진공학회지
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    • 제20권5호
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    • pp.374-380
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    • 2011
  • 니켈촉매 막을 증착시킨 산화규산 기판위에 아세틸렌기체와 수소기체를 원료로 육불화황기체를 첨가기체로 탄소코일을 증착하였다. 육불화황이 투입되는 단계에 따라 성장된 탄소코일의 특성(형성 밀도, 형상)을 조사하였다. 육불화황을 연속적으로 주입하였을 경우 선형, 마이크로크기 코일, 나노크기 코일, 그리고 파동형 나노크기 코일 등 다양한 형태의 탄소코일들이 성장하였다. 하지만, 탄소코일 초기 증착단계에서 1분정도의 짧은시간 동안 육불화황을 주입한 경우 나노크기의 탄소코일 형상만을 대부분 얻을 수 있었다. 탄소코일 합성반응시간이 1분 정도 지체된 후의 단계에서 짧은시간 동안의 육불화황 주입은 코일형상 제어를 저해하였다. 따라서, 육불화황의 주입 시간과 주입단계가 탄소 코일의 형상을 결정하는 중요한 요인임을 알 수 있었다.