• 대한수의학회지
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• 제4권1호
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• pp.27-33
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• 1964

In the treatment of mice Aureomycin, Oil penicillin, Achromycin, Ambrasynth and Terramycin were effective on the Black-leg disease when they were administered about 4 to 5 hours before the death of control animals. Synthomycetin, however, was observed to be effective when administered 8 hours or more before the control death. Streptomycin seemed to be rather less effective than Black leg antiserum. It was not effective at all when given 19 hours before the death of control animal although there was a delay of taking death by 5 hours in the treated group. As was in mice, Streptomycin was little effective in the treatment of calves, while other antibiotics showed fine efficacy on the diseased animals. The diseased animals, when given with anitibiotics 37 hours before the death of control showed the rise of temperature($41^{\circ}C$ or more), swelling and redness on the site of infection and then recovcred to normal stage. In the treatment of calves, Aureomycin only delayed the taking death of the deseased animals by 111 hours when administered 4 hours before the death of control animals. And other antibiotics, when given 4 hours before the death of control animals were effective, although the deseased animls developed symptoms such as hard breathing, anorexia and dropsical swellings. Oil penicillin was observed to be comparatively larger in its efficacy on the treatment of Black leg disease.

• Child Health Nursing Research
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• 제8권3호
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• pp.260-271
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• 2002

This study was performed to identify the level of stress recognized by the parents as a support system for their infant patients who were hospitalized in an emergency department, thus to provide the resulting data as the basic material of care intervention for the families of infant patients. This study subjected the parents with infant patients who were hospitalized in emergency department of C University Hospital in Daejeon, and the data was collected from questionnaires for them, dating from Mar. 20, to Jun. 24, 2001 This study used the tool(30 questions) which was originally developed by Ji, Dong-ok (1992) for measuring the stress of families of infant patients in emergency room, and then was modified and complemented by this researcher suitably for infant patients. Collected data was statistically analyzed with frequency, percentage, mean, standard deviation, t-test, ANOVA, by using SPSS WIN10.0 program, and the results were as follows: 1. The stress of parents with infant patients hospitalized in emergency department averaged 3.31 on the basis of 5-point measure, which means that they felt stress beyond means. 2. The factor with high average out of stress factors the parents of infant patients recognized included the followings: 'about the pain of infant patients due to examination(3.91±1.00)'; 'about rare opportunity to be in contact with physician(3.78±1.09)'; 'delay in emergent treatment required for infant patients(3.75±1.31)'; 'delay in the general treatment of infant patients(3.72±1.32)'. Factors of the stress level includes the followings: 'care and medical treatment'(3.46±.72); 'body and diseases'(3.41±.97)'; 'lack of information and supportable resources (3.25±.77)'; and so on. 3. For the stress level according to general characteristics, there were statistically significant differences in the result of the condition of infant patients, medical treatment(P<.01), religion, the procedure of treatment(P<.05). With little preceding studies for infant patients hospitalized in emergency department, this study looked through the level of stress recognized by the parents of infant patients. Based on the comprehension on the parents with infant patients and the knowledge on stress factors recognized by the parents, it is expected that we can seek the methods of care intervention such as explanation of care and treatment procedures, unit policies, continuous interest and emotional supports as well as the provision of information to understand the responses of parents and reduce accompanied stresses.

• 대한두개안면성형외과학회지
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• 제14권2호
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• pp.73-80
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• 2013

It is important to distinguish deformational plagiocephaly from craniosynostosis, the two conditions are different with respect to clinical progression and treatment options. Deformational plagiocephaly is diagnosed based on the patient's medical history and physical examination. Until recently, there has been no standardized method of evaluation. Visual assessment, anthropometric assessment, digital scanning, and radiologic evaluation are mostly commonly used modalities for diagnosis and assessment. Treatment of deformational plagiocephaly requires an understanding of natural progression of the disease. Deformational plagiocephaly should be classified according to its severity before the proper method and time for treatment are determined. Treatment includes repositioning, physiotherapy and remodeling with the use of orthotic devices. In general, repositioning is preferred for patients younger than six months old while treatment with the use of orthotic devices such as helmet is preferred for patients over six months old. Moreover, treatment with the use of orthotic devices is also favored for severe plagiocephaly. There is continuing research on the relation between deformational plagiocephaly and developmental delay.

• Clinical and Experimental Pediatrics
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• 제61권2호
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• pp.49-52
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• 2018

Purpose: Tularemia is an infection caused by Francisella tularensis. Its diagnosis and treatment may be difficult in many cases. The aim of this study was to evaluate treatment modalities for pediatric tularemia patients who do not respond to medical treatment. Methods: A single-center, retrospective study was performed. A total of 19 children with oropharyngeal tularemia were included. Results: Before diagnosis, the duration of symptoms in patients was $32.15{\pm}17.8days$. The most common lymph node localization was the cervical chain. All patients received medical treatment (e.g., streptomycin, gentamicin, ciprofloxacin, and doxycycline). Patients who had been given streptomycin, gentamicin, or doxycycline as initial therapy for 10-14 days showed no response to treatment, and recovery was only achieved after administration of oral ciprofloxacin. Response to treatment was delayed in 5 patients who had been given ciprofloxacin as initial therapy. Surgical incision and drainage were performed in 9 patients (47.5%) who were unresponsive to medical treatment and were experiencing abcess formation and suppuration. Five patients (26.3%) underwent total mass excision, and 2 patients (10.5%) underwent fine-needle aspiration to reach a conclusive differential diagnosis and inform treatment. Conclusion: The causes of treatment failure in tularemia include delay in effective treatment and the development of suppurating lymph nodes.

• Journal of Dairy Science and Biotechnology
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• 제35권4호
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• pp.270-285
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• 2017

Among milk proteins, caseins are not subjected to chemical changes during heat treatment of milk; however, whey proteins are partially denatured following heat treatment. The degree of whey protein denaturation by heat treatment is decreased in the order of high temperature short time (HTST) > low temperature long time (LTLT) > direct-ultra-high temperature (UHT) > indirect-UHT. As a result of heat treatment, several changes, including variations in milk nitrogen, interactions between beta-lactoglobulin and k-casein, variations in calcium sulfate and casein micelle size, and delay of milk coagulation by chymosin action, were observed. Lysine, an important essential amino acid found in milk, was partially inactivated during heat treatment. Therefore, the available amount of lysine decreased slightly (1~4% decrease) after heat treatment, However, the influence of heat treatment on the nutritional value of milk was negligible. Nutritional value and nitrogen balance did not differ significantly between UHT and LTLT in milk. In conclusion, our results showed that heat treatment of milk did not alter protein quality. Whey proteins denatured to a limited extent during the heat treatment process, and the nutritional value and protein quality were unaffected by heat treatment.

• Journal of Applied Biological Chemistry
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• 제43권4호
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• pp.211-217
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• 2000

Oxidative stress is implicated in a number of diseases, in ageing of organisms, and in damage to plants that have been exposed to freezing and thawing or water stress. From the perspective of yeast as a model eukaryotic system, this article reviews the systems that are involved in the cellular responses to exposure to reactive oxygen species (ROS) generated during aerobic growth of the organism. The discussion includes the defense systems involved, the ability of cells to adapt to ROS treatment, cell-division cycle delay and the systems regulating gene expression that are activated by oxidative stress.

• 한국작물학회지
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• 제65권4호
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• pp.353-364
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• 2020

국내 주요 재배 콩 품종을 대상으로 수확 지연 시 강우에 따른 피해 양상 및 수확방법에 따른 종실 및 수량 특성을 분석하고자 본 실험을 수행하였으며, 결과를 요약하면 아래와 같다. 1. 품종별 탈립률의 차이가 나타났으며, 대원콩에서는 강우처리 및 예취 후 비닐피복 에서 40일 수확 지연 시 탈립률이 5.3% 증가하였으나, 풍산나물콩은 강우 무처리 및 예취 후 비닐피복에서 40일 수확 지연 시 41.8%까지 증가하였다. 2. 100립중은 강우처리 및 수확방법에 따라 수확이 지연될수록 입중이 미세하게 낮아지는 경향을 보였으나 강우처리 후 포장 수확한 경우를 제외하고 유의성이 인정되지 않았다. 3. 수량은 대원콩의 경우 강우처리 및 예취 후 비닐피복 할 경우 수량 감소가 가장 크게 나타났으며 적기 수확기 이후 40일 지연 수확할 경우 일당 평균 감수율은 0.8 kg ha^-1, 풍산나물콩은 강우 무처리 및 예취 후 비닐피복에서 적기 수확기 이후 40일 지연 수확할 경우 일당 평균 감수율은 3.4 kg ha^-1로 나타났다. 4. 강우처리 및 수확방법에 따른 이병립률은 유의한 차이가 나타났으며, 수확 지연에 따라 이병률도 증가하였으며, 강우처리 및 포장 수확에서 이병률이 가장 높았고, 40일 지연 수확 시 대원콩은 7.0%, 풍산나물콩은 4.0%로 증가하였다. 5. 강우 무처리시 포장 수확 및 예취 후 비닐피복의 수확방법에 따른 차이는 적었으며, 수확이 지연되어도 95%이상의 발아율을 유지하였다. 강우처리 시 수확 지연에 따라 발아율은 현저하게 낮아졌으며, 포장 수확의 경우 40일 수확을 지연하면 대원콩은 77.2%, 풍산나물콩은 76.5%까지 발아율이 감소하였다. 6. 조단백질 함량은 시험 품종 모두 강우처리에 따라 무처리구에서 다소 높은 것으로 나타났으며, 수확방법에서도 예취 후 비닐피복에 비하여 포장 수확에서 높은 함량을 나타냈다. 조지방 함량은 강우를 처리할 경우 다소 높게 나타났으며, 수확방법에서는 예취 후 비닐피복에서 높은 함량을 보였다. 7. 100립중은 개별 처리에 대한 효과가 적어 처리간 상호적용 효과가 적었으나, 이병립률 및 발아율은 처리간 상호작용 효과가 높았다. 8. 품종별 탈립률의 처리간 상호작용 효과는 수량의 상호작용 효과와 같은 양상을 나타내어, 탈립률이 수량에 가장 영향을 준 것으로 나타났다.

• 생명과학회지
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• 제11권5호
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• pp.447-456
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• 2001

임신랫드에서 fluoroquinolone 항균제 DW-116에 의해 유발된 발생독성이 모동물의 사료섭취량 감소에 의한 영양 결핍이 주요 원인인지 아니면 DW-116이 배.태자에 직접적으로 작용하여 유발된것인지를 조사하고자 시험물질을 랫드에 임신 6일에서 16일까지 0 및 500 mg/kg 용량으로 반복 경구투여하였다. 사료제한군은 시험물질 투여군의 모동물의 섭취한 동일한 양의 사료를 제한급여하였다. 모든모동물을 임신 20일째에 제왕절개하였고, 모독성 및 발생독성을 평가하였다. 시험물질 투여군에서는 독성증상과 체중의 감소, 투여 및 투여후 기간의 체중증가 억제, 사료섭취량의 감소를 포함하는 모독성이 부형제대조군및 사료제한군에 비해 현저하게 증가하였다. 또한, 태자사망의 증가, 생존태자의 감소, 태자체중과 태반중량의 감소, 태자기형의 증가 및 골환지연을 포함하는 발생독성도 현저하게 증가하였다. 반면, 사료제한군에서는 모체 및 태자에서 경미한 독성고견만 인정되었고, 태자사망이나 태자기형 등의 심각한 발생독성은 관찰되지 않았다. 결론적으로 시험물질투여군에서 관찰된 발생독성은 사료섭취량의 감소에 의한 모체의 영양결핍에 기인된 것이 아니라 DW-116의 투여에 기인된 직접효과인 것으로 판단된다.

• Journal of Korean Neurosurgical Society
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• 제40권4호
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• pp.289-292
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• 2006

Thoracic spinal actinomycosis causing epidural abscess and significant spinal cord compression is very rare. A case is presented of a 56-year-old woman with rapid progressive upper back pain and weakness in both legs without evidence of systemic infection. Magnetic resonance imaging revealed a thoracic epidural enhancing lesion at the T1-T5 level. After decompression by laminectomy, precise diagnosis was accomplished using specific histopathological studies of the surgical specimens. A histopathologic findings showing typical Actinomyces sulfur granules surrounded by acute inflammatory cells. The clinical radiological findings of spinal actinomycosis closely resemble metastatic tumors and other infectious processes. Delay in diagnosis and treatment can significantly worsen the condition of patient.

• 한국건축시공학회:학술대회논문집
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• 한국건축시공학회 2019년도 춘계 학술논문 발표대회
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• pp.57-58
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• 2019

Precast concrete finishing panels can be implemented in different colors, textures and designs relatively freely by different designers in different finishing materials. Therefore, we tried to develop a PC finishing panel that can be applied in the field by using various color pigment and concrete surface retardation method and polishing method.