• 대한한방내과학회지
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• 제34권2호
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• pp.134-146
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• 2013

Objectives : Auklandia Lappa (ALE) is one of the herbs used frequently to treat abdominal pain and diarrhea and reported anti-inflammatory activity by suppressing proinflammatory cytokines. This study was designed to investigate whether ALE could show protective activities on experimental colitis induced by dextran sulfate sodium (DSS) models. Methods : Colitis was induced by DSS in Balb/c mice. ALE 10, 30, 100 and 300 mg/kg were orally administered twice a day for 7 days in DSS model. Mice weight was measured daily. Scoring of clinical findings was measured every other day. Colon length, edema, fecal blood and histological damages were assessed at day 7 in DSS model. In histological analysis, we checked cryptal glands, surface epithelium, submucosa, transmural, stroma and scored degree of inflammatory cell damage by modified histological scoring. We also calculated cytokines concentrations including IFN-${\gamma}$, TNF-${\alpha}$, IL-6, IL-$1{\beta}$, IL-17, IL-23, IL-10 and TGF-${\beta}1$ by Biometric Multiplex Cytokine Profiling method. Results : ALE showed the protective effects on DSS-induced experimental colitis. ALE inhibited shortening of colon length and histological damages of colon does-dependently, but it did not inhibit weight loss. ALE also inhibited IFN-${\gamma}$ and IL-6 expression, and upregulated cytokines (IL-10, TGF-${\beta}1$) related to regulatory T cell differentiation and proliferation. Conclusions : The current results demonstrate the clinical utility of ALE in traditional medicine and indicate the possibility of potent drug development of inflammatory bowel diseases from natural products. Further investigations for exact mechanisms will be needed.

• Advances in pediatric surgery
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• 제11권2호
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• pp.115-122
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• 2005

Falls from a height are the leading cause of injury and death among urban children. This study describes the incidence, clinical characteristics, and treatment results of children under 15 year of age who fell from a height of more than one meter and were admitted for abdominal injury. The medical records of 585 consecutive patients treated between January 1997 and December 2003 at Ewha Womans University Mokdong Hospital were analyzed retrospectively. The falling heights were 1 to 31.2 meters, and 28 patients(4.8 %) suffered from blunt abdominal trauma. The male to female ratio was 2.1: 1. The median age of the victims was 5.5 years, and the median height fallen was 3 meters. Fifteen patients (53.6 %) were injured during the summer and seventy-nine percent of the falls occurred between noon and 9 pm. Eighteen (64.3 %) of falls occurred in residential place and 19(67.8 %) of patients arrived at the emergency department within 30 minutes of the accident. Only 16 patients (57.1 %) complained of abdominal pain. Liver injuries were found in 12(42.9 %), spleen injuries in 5(17.9 %), kidney injuries 3(10.7 %), pancreatic injuries in 1(3.6 %) and nonspecific abdominal injuries in 9(32.1 %) cases. Increased SGOT and SGPT were found in 23(82.2 %) and 18(64.3 %) cases. Eleven patients (39.3 %) had associated head injuries. Limb injuries were present in 17.9% and thoracic injuries in 7.1%. Twenty-five patients (89.3 %) recovered without operation. The median length of hospital stay was 6 days (2 -20 days). Despite the absence of abdominal symptoms or shock, falls from a height in children may carry significant intra-abdominal organ injuries. The height falling could not predict the degree of the abdominal injury. For the evaluation of potential abdominal injuries, CT scan should be utilized.

• 한국전문물리치료학회지
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• 제26권1호
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• pp.28-36
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• 2019

Background: Temporomandibular disorder (TMD) is characterized by pain and limited range of motion in the jaw. TMD patients generally prefer to chew on the unaffected or less-affected side, and this tendency often results in asymmetries in masseter muscle thickness and range of mandibular motion. Objects: The purpose of this study was to compare the asymmetries in masseter muscle thickness and range of mandibular motion in subjects with and without temporomandibular disorders. Methods: Thirty-nine subjects were divided into two groups: A TMD group ($n_1=19$) and a control group ($n_2=20$). The jaw opening range and laterotrusion were measured using a digital vernier caliper. The masseter muscle thickness was examined in both the resting state and the maximal clenching state using ultrasonography. The absolute asymmetry indices calculated based on the laterotrusion and masseter muscle thickness of the respective right and left sides. A two-way ANOVA and a Mann-Whitney U test were used for statistical analysis. Results: No significant different was found in the masseter muscle thickness between the TMD and control group. A significant difference was found in the absolute asymmetry indices of mandibular laterotrusion between the TMD and control groups (p<.05). Furthermore, the ranges of jaw opening were significantly different between males and females (p<.05). The absolute asymmetry index values of masseter muscle thickness at rest and during maximal clenching were also significantly different between males and females (p<.05). Conclusion: These results demonstrated that the subjects with TMD had a larger degree of asymmetry in laterotrusion than those without TMD. Therefore, a physiotherapy program needs to be designed to restore normal laterotrusion capacities for TMD subjects. These results also showed that female subjects had greater absolute asymmetry indices in masseter muscle thickness than male subjects. Therefore, more training is needed to promote bilaterally balanced chewing among women.

• 대한족부족관절학회지
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• 제10권2호
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• pp.247-249
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• 2006

Purpose: The neural injuries by the sprain around the ankle joint may contribute the chronic pain. Authors analyzed the incidence and the contributing factor of the neural injuries in ankle sprain. Materials and Methods: 52 patients (54 cases) were involved in this retrospective study. Patient with diabetes or spinal disease were excluded. Plain radiograph and MR image were evaluated. Treatments were consisted of cast immobilization for 4 weeks with weight bearing ambulation following bracing for 8 weeks. Neurologic evaluation were performed at 3 months, 6 months, 12 months post-injury period and each neural injury were confirmed by electromyography or lidocaine block test. Results: The average age was 39 years old and 34 cases were male and 20 cases were female. Rupture of the anterior talofibular ligament was observed in 48 cases, distal anterior tibiofibular ligament in 37 cases, calcaneofibular ligament in 6 cases. One cases revealed no injury of the ligament. Neural injuries around ankle was observed in 13 cases ; superficial peroneal nerve in 9 cases, sural nerve in 5 cases, saphanous nerve in 1 case. Neural injury was not influenced by the degree of ligament injuries but by the incidence numbers of ankle sprain. All cases were treated conservatively and symptom was subsided in all but 2 cases. Conclusion : Although the incidence is relatively low, the neural injuries in ankle sprain may occur in the recurrent ankle sprain and conservative treatment for neural injuries is satisfactory.

• 지역사회간호학회지
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• 제16권4호
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• pp.446-457
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• 2005

Purpose: The purpose of this study was to analyse researches on nursing intervention for elderly health promotion. Method: A literature review of 38 researches was carried out using guidelines developed by the present researchers. Result: The research papers studied in this research were theses written for doctoral or master's degree and published between 1994 to 2004. These researches applied nursing intervention for health promotion of elders and used experimental study design. The average period of nursing intervention was about 9 weeks and the average frequency was three times per week. As for major characteristics of subject groups, most of them were over 65 years old (76.3%) and resided in community (65.8%), and each group consisted of 10 to 29 elders. The dependent variables used in these studies included physiological variables (blood pressure, blood cholesterol level, pulmonary function, fasting blood sugar, blood cortisol level, body mass etc.), psychologic variables (depression, quality of life, life satisfaction, loneliness, anxiety etc.), cognitive variables (perceived benefits, perceived barriers, self-efficacy, self-concept, subjective health status etc.), activities of daily livings, health promotion behavior, pain, risks of fall, and variables related to Trans Theoretical Model. The majority of these studies (78.9%) applied exercise programs for health promotion including exercise motivating programs (15.8%). Conclusion: We suggest that more various nursing interventions must be applied to promote elders' health and to take care of their chronic diseases.

• 대한정형외과학회지
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• 제55권2호
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• pp.103-116
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• 2020

회전근 개 파열은 인구의 고령화 및 영상 진단의 발전 등으로 인해 그 빈도가 빠르게 증가하고 있다. 최근에는 관절경적 봉합술이 일반화되어 있으며 수술 결과 역시 관혈적 봉합술과 대등한 유합률을 보이고 있다. 관절경적 수술 자체가 최소 침습적 방법이므로 수술 후 통증 감소와 조기 기능 향상이라는 부가적인 이점을 가질 수 있지만 최근에는 견관절의 관절경 수술 후 환자의 기능 회복을 더욱 향상시키기 위한 다양한 방법에 대한 관심이 높아지고 있다. 견관절 관절경 수술 후 기능 회복 치료 방법들은 수술 후 시기별로 나누어져 있으며 각 단계별로 활발히 연구되고 개선되고 있다. 그러나 각 시기별, 재활 단계별, 환자 개개인의 특성, 회전근개 파열의 정도 및 기저 질환에 따라 다양한 방법들이 많아 관절경적 회전근 개 봉합술 후 정상 견관절 상태로의 기능 회복을 위해 각 시기에 맞는 적합한 견관절의 기능 회복 방법에 대한 확립이 필요하다고 할 수 있다.

• 대한관절경학회지
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• 제10권2호
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• pp.135-140
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• 2006

불안정성 견관절에 대한 진단과 치료는 정형외과 영역에서 가장 어려운 분야 중에 하나이다. 관절와 위에서 움직이는 상완골두의 아탈구와 정상적인 전이, 통증과 기능 저하를 일으키는 이완의 정도는 구별하기가 용이하지 않는 경우가 많다. 불행하게도 이 불안정성을 일으키는 모든 병변에 시행할 수 있는 가장 좋은 한가지의 치료법은 개발되어 있지 않다. 그러므로 불안정성의 방향과 정도뿐만 아니라 동반된 문제까지도 정확히 진단하는 것이 절대 필요하다. 해부학적 결손은 반드시 확인해야 한다. 불안정성에 대한 봉합술의 실패에 영향을 미칠 수 잇는 흔한 요인은 다음과 같다. 정확한 해부학적 병리소견을 확인하는 올바른 진단, 올바른 치료 방법에 대한 이유, 필요 없는 내고정물의 사용이나 불안정성, 관절염, 신경 및 혈관 손상 등을 남길 수 있는 도달법의 사용과 같은 기술적 결함 등이 있다. 술후 견관절의 안정성, 유연성, 지구력을 회복시켜 강도높은 스포츠나 노동에 복귀할 수 있는 잘 준비된 재활을 통해 추가적인 손상을 막아야 한다.

• 대한간호학회지
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• 제24권1호
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• pp.96-114
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• 1994

This study was carried out to describe and analyze experimental studies conducted in graduates nursing degree. Of 170 experimental studies conducted during the past three decades between 1962 and August 1991, 150 studies were available, including 124 master’s and 26 doctoral theses. This study examined their general characteristics and detailed research methods using percentiles. The results were as follows 1. Most of the studies adopted a quasi-experimental design. 2. The subjects of the studies were chosen by convenience sampling except for two studies whose subjects were drawn by randomization. Studies comparing experimental and control groups were in the highest proportion and the most frequent sample sizes of each group were 21 to 30 for both experimental and control groups. 3. As to measurement, physiological measures were most frequent followed by psychsociological measures and active report questionnaires. Each study, on average, adopted two kind of measurement tools. Studies in which the data collection period was of 1~2 months were in the highest pro-portion. 4. All doctoral theses and 67.0% of master’s theses examined specific research hypotheses. Of these studies, the results of 92.5% supported the hypotheses. 5. Parametric statistics were the major analytical methods. In particular, t-test was used most frequently followed by Chi square, F-test, and Pearson Correlation Coefficients. 6. Patients were the most frequent study subjects. Frequent nursing interventions were information and education followed by support, distraction, and nursing treatments. 7. With regards to the dependent variables, “feelings” such as anxiety, pain, and depression were most frequent. In addition “exchanging” such as restoring, metabolism, cardiopulmonary function, infection and vital signs were adopted as the dependent variables in 29.1％ of the studies examined, while 12.3% of the studies selected “choosing” such as stress, health behavior, or role performance.

• 정보처리학회논문지B
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• 제10B권5호
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• pp.503-508
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• 2003

척추에 대한 외과수술은 신경조직을 손상하지 않아야 하기 때문에 수술 절차가 신중하게 계획되고 고도의 정밀을 요구한다. 척추성형술(verte-broplasty)은 골다공증으로 인한 척추의 골절을 치료하기 위해 제안된 비교적 새로운 외과적인 수술방법으로 최소침습적인 수술 기법으로 피부를 통하여 골절된 척추부위에 구멍을 내고 그곳에 PMMA(polymethylmethacrylate)라 불리는 골시멘트(bone cement)를 주입하여 치료하는 방법이다. 최근의 연구결과, 수술 후 즉각적인 고통의 경감을 가져오며, 골다공증으로 인한 골절부위에 강도가 강한 골시멘트를 주입하게 됨으로써 골다공증 척추체에 구조적인 안정성을 제공해 주는 것으로 알려져 있다. 수술 후 발생하는 합병증의 대부분은 과도한 골시멘트의 주입으로 인한 것으로 알려져 있으며, 따라서 척추성형술의 치료에 가장 중요한 요인은 주입한 골시멘트의 양을 조절하는 것이다. 이에 본 연구에서는 환자의 컴퓨터단층촬영(computer tomography)을 통하여 획득한 영상을 토대로 척추성형술 시술시 필요한 의료 영상 시스템을 설계 및 개발하고, 텍스처 분석을 통하여 개개인의 환자에게 필요한 골시멘트의 양을 계산하는 알고리즘을 개발하여 이를 실제 환자의 시술시에 적용해 보았다. 결과적으로 본 시스템은 척추성형술시에 최적의 골시멘트의 양을 예측할 수 있었으며, 정형외과의 다른 부위의 수술시에도 적용가능성을 확인할 수 있었다.

• 대한통합의학회지
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• 제9권2호
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• pp.63-73
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• 2021

Purpose : Selective functional movement assessment(SFMA) is a movement-based assessment tool designed for clinicians to diagnose and treat pain and functional physical problems. This concept is used for assistance in occupations related to movement, including clinical medical personnel, such as physical therapists, physical education instructors, and athlete coaches. Although this concept is widely used by clinicians, research and scientific proofs are relatively insufficient. This study aimed to review the literature on the understanding, reliability and effectiveness of SFMA, and to consider its role in the future of rehabilitation. Methods : In this review, a total of nine articles were selected according to the eligibility criteria of three major thesis topics. The main topics covered in the literature are reliability and effectiveness of clinical use of SFMA. To gather research articles, we searched official term 'Selective Functional Movement Assessment'. Among the searched 60 studies, nine were mentioned in this study that contained overlapping information and matched our desired topic. We reviewed four reliability analyses, four case reports, and one experimental study. Results : Reliability has an intermediate degree between high raters and within raters. The validity of the SFMA system is influenced by a combination of experience and logic; hence, further improvement is needed. Therefore, if the intervention was effective based on the diagnosis result, then biomechanical evidence is necessary to further support the claim. Conclusion : In future research, to use SFMA as a diagnostic tool with high accuracy, it is necessary to improve the reliability of the main problem through breakout, support for guidelines and validity and efficiency.