• Asian Pacific Journal of Cancer Prevention
• /
• v.15 no.21
• /
• pp.9391-9394
• /
• 2014

Purpose: To evaluate the effect of internal-external percutaneous transhepatic biliary drainage (IEPTBD) for patients with malignant obstructive jaundice. Methods: During the period of January 2008 and July 2013, internal-external drainage was performed in 42 patients with malignant obstructive jaundice. During the procedure, if the guide wire could pass through the occlusion and into the duodenum, IEPTBD was performed. External drainage biliary catheter was placed if the occlusion was not crossed. Newly onset of infection, degree of bilirubin decrease and the survival time of patients were selected as parameters to evaluate the effect of IEPTBD. Results: Twenty newly onset of infection were recorded after procedure and new infectious rate was 47.6%. Sixteen patients with infection (3 before, 13 after drainage) were uncontrolled after procedure, 12 of them (3 before, 9 after drainage) died within 1 month. The mean TBIL levels declined from 299.53 umol/L before drainage to 257.62 umol/L after drainage, while uninfected group decline from 274.86 umol/L to 132.34 umol/Lp (P < 0.5). The median survival time for uninfected group was 107 days, and for infection group was 43 days (P < 0.05). Conclusions: The IEPTBD drainage may increase the chance of biliary infection, reduce bile drainage efficiency and decrease the long-term prognosis, and the external drainage is a better choice for patients with malignant obstructive jaundice need to biliary drainage.

• Herbal Formula Science
• /
• v.17 no.1
• /
• pp.113-120
• /
• 2009

Objectives : This study focuses on the effect of the extract which We manufactured by adding Aliium sativum to Ojayeonjonghwan on the amount of semen, the number and the activity of sperm. Methods : We observed any changes in the amount of semen, the number and the activity of sperm after orally administering the test drug for thirty days and taking semen samples from a selected group of men - healthy men in their 20s, as well as men in their 40s who were feeling a decrease in energy. Results : This experiment showed the result that the amount of semen increased by adding Aliium sativum to Ojayeonjonghwan in the case of men in their 20s, but did not show a statistically significant result. It showed the result that the amount of semen increased by a statistically significant level as well as the activity of sperm. Consequently, the result indicated that orally administering the extract added Aliium sativum to Ojayeonjonghwan increased the amount of semen, the number and the activity of sperm for men in their 20s. Men in their 40s who are feeling a decline in energy generally decreased the amount of semen, the number and the ratio of activity of sperm. However the amount of semen remarkably increased and the number and the activity of sperm increased but the result was not statistically significant after orally administering the test drug for thirty days. Conclution : Eventually, the result after orally administering the test drug to the group of men in their 20s and 40s for thirty days indicated that both groups increased the amount of semen, number of sperm and activity of sperm to a statistically significant degree.

• Korean Journal of Weed Science
• /
• v.31 no.3
• /
• pp.271-278
• /
• 2011

The allelopathic effects of Lantana camara L. (Family:Verbenaceae) on germination and seedling establishment of some agricultural crops and weed species have been identified. Aqueous extracts of dry leaves and contaminated soil where L. camara is grown were used to verify allelopathic effect on seed germination of five bioassay species; Raphanus sativas, Capsicum annum, Lycopersicum esculantem, Crotalaria juncia and Chromoleana odorata. Fifty seeds from each bioassay species were placed in a petri dish containing leaf extracts or contaminated soil, and seed germination were examined after 3 days. The plant house experiments were carried out to evaluate the impact of L. camara contaminated soil and leaf debris using L. esculantem as the indicator plant. Seed germination of L. esculentem, C. junica and Capsicum annum was significantly inhibited by L. camara contaminated soil. However, the degree of inhibition varied among the bioassay species. The aqueous extract of dry leaves of L. camara was highly phytotoxic and it significantly reduced seed germination of all bioassay species. There was a decline in plant height, leaf area and shoot dry weight of tomato only in early growth stages when grown in L. camara contaminated soils. However, incorporation of leaf debris into soil affected the vegetative growth of tomato in early stages when the leaf debris concentration was increased. Growth recovered at the latter part of the life cycle. On the basis of these results it can be concluded that the allelochemicals in L. camara contaminated soils are harmful to the seed germination of crop species. The adverse effect was present only during the early growth stages and it did not suppress the latter part of the plant growth. These responses are attributed to allelopathic effects which need confirmation under field conditions.

• Journal of Animal Science and Technology
• /
• v.56 no.8
• /
• pp.33.1-33.8
• /
• 2014

Background: Sox 9 is a major marker of chondrocyte differentiation. When chondrocytes are cultured in vitro they progressively de-differentiate and this is associated with a decline in Sox 9 expression. The active form of vitamin D, 1, 25 $(OH)_2D_3$ has been shown to be protective of cartilage in both humans and animals. In this study equine articular chondrocytes were grown in culture and the effects of 1, 25 $(OH)_2D_3$ upon Sox 9 expression examined. The expression of the transient receptor potential vanilloid (TRPV) ion channels 5 and 6 in equine chondrocytes in vitro, we have previously shown, is inversely correlated with de-differentiation. The expression of these channels in response to 1, 25 $(OH)_2D_3$ administration was therefore also examined. Results: The active form of vitamin D (1, 25 $(OH)_2D_3$ when administered to cultured equine chondrocytes at two different concentrations significantly increased the expression of Sox 9 at both. In contrast 1, 25 $(OH)_2D_3$ had no significant effect upon the expression of either TRPV 5 or 6 at either the protein or the mRNA level. Conclusions: The increased expression of Sox 9, in equine articular chondrocytes in vitro, in response to the active form of vitamin D suggests that this compound could be utilized to inhibit the progressive de-differentiation that is normally observed in these cells. It is also supportive of previous studies indicating that $1{\alpha}$, 25-dihydroxyvitamin $D_3$ can have a protective effect upon cartilage in animals in vivo. The previously observed correlation between the degree of differentiation and the expression levels of TRPV 5/6 had suggested that these ion channels may have a direct involvement in, or be modulated by, the differentiation process in vitro. The data in the present study do not support this.

• Journal of Korean Society of Rural Planning
• /
• v.22 no.3
• /
• pp.107-118
• /
• 2016

In order to ensure revenue of agricultural products which have encountered the dramatic decline of prices in distribution, the export of the domestic farm produce was started and it has been considered to play the significant role to make fundamentals for securing the stable revenue of farms and future of agricultural industries. The Korean government has endeavored to increase scale and volume of export and make the stable structure for export transaction by supporting government policies. Since the export of the agricultural products was influenced by multiple and uncertain factors such as the gap of GDP, distance, the difference of climatess between countries, in this study of agricultural exports, the attributes of export according to changed factors are derived by using RCA and gravity model. As the complexity of export environment has been increased compared to the past, it is necessary to analyze the attributes of agricultural exports. In this study, by using network theory, trade network of agricultural product, the periodic changes of relations, the changes of centrality and maxium flow are derived. Even though the trade quantity of existing agricultural fresh products are still small, the study derived the need to vertical integration for expanding agricultural product export by applying network theory.

• Pediatric Gastroenterology, Hepatology & Nutrition
• /
• v.17 no.3
• /
• pp.162-169
• /
• 2014

Purpose: To study temporal pattern of serum liver enzymes levels in newborns with hepatic injury associated with birth asphyxia (BA). Methods: Singleton term newborns with BA and ${\leq}72$ hours of age admitted to neonatal intensive care unit were prospectively enrolled. Term newborns with physiological jaundice and without BA were studied as controls. Serum liver enzymes were measured at <24 hours, 24-72 hours, and at 6-12 days of age for cases and at 1-6 days of age for controls. BA was defined by 1 minute Apgar score <7 or delayed or absent cry with hypoxic ischemic encephalopathy. BA-associated liver injury was defined as serum alanine aminotransferase (ALT) elevation beyond +2 standard deviation (ALT > +2 SD) above the mean of control subjects at any of the three time points. Results: Sixty controls and 62 cases were enrolled. Thirty-five cases (56%) developed BA-associated liver injury (ALT>81 IU/L). They had higher serum levels of ALT, aspartate aminotransferase, lactate dehydrogenase than the control infants, with peak at 24-72 hours. In controls, serum liver enzyme levels were significantly higher in appropriate-for-date (AFD) babies than small-for-date (SFD) babies. Serum enzyme pattern and extent of elevation were comparable between SFD and AFD babies. Degree of serum liver enzyme elevation had no relationship with severity of hypoxic encephalopathy. Conclusion: Serum liver enzyme elevation is common in BA; it peaks at 24-72 hours followed by a sharp decline by 6-12 days of age. Pattern and extent of enzyme elevation are comparable between SFD and AFD babies.

• Journal of the Korean Society of Environmental Restoration Technology
• /
• v.20 no.4
• /
• pp.1-13
• /
• 2017

The purpose of this study is to analyze a term of decade of water quality data of the Mulgum intake station on the Nakdong river(dam) to find the cause of algal blooms and to set an alternative to prevent artificial lake water pollution. Our study shows that water quality changes have regular periodic regularity and there was a certain correlation between specific analytical items. According to the analysis results of each factor, the decline in precipitation was not the main reason for algal blooms. TP concentration had a slight effect on Chl-a concentration but was not a limiting nutrient of a bloom. TN concentration had a strong correlation with Chl-a and strongly negative correlation with temperature, but was not a bloom's limiting nutrient, and was only a dependent variable. As the temperature was negatively correlated with the Chl-a concentration, it is found that the aspect of the ecological influence of the temperature was the most important factor of the phytoplankton concentration change. The N/P ratio lies under a power function with a high degree of reliability by the TP concentration, and the phenomenon appeared to be the same as the results of two other comparative areas. This result confirms that TN is dependent on TP and the biota in the lake that TN is a dependent variable whose concentration is determined by TP it. In conclusion, the increase in lake bloom is the result of a food chain change, and it is necessary to control the ecosystem by the food chain in the lake in order to reduce the lake's bloom. In particular, it is important to keep the benthic ecosystem as wide as possible in the aerobic state.

• The Korean Journal of Pain
• /
• v.28 no.3
• /
• pp.203-209
• /
• 2015

Background: Ketorolac has been used as a postoperative analgesia in combination with opioids. However, the use of ketorolac may produce serious side effects in vulnerable patients. Propacetamol is known to induce fewer side effects than ketorolac because it mainly affects the central nervous system. We compared the analgesic effects and patient satisfaction levels of each drug when combined with fentanyl patient-controlled analgesia (PCA). Methods: The patients were divided into two groups, each with n = 46. The patients in each group were given 60 mg of ketorolac or 2 g of propacetamol (mixed with fentanyl) for 10 minutes. The patients were then given 180 mg of ketorolac or 8 g of propacetamol (mixed with fentanyl and ramosetron) through PCA. We assessed the visual analogue pain scale (VAS) at the time point immediately before administration (baseline) and at 15, 30, and 60 minutes, and 24 hours after administration. Also, the side effects of each regimen and each patient's degree of satisfaction were assessed. Results: There was a significant decline in the VAS score in both groups (P < 0.05). However, there were no significant differences in the VAS scores between the groups at each time point. Satisfaction scores between the groups showed no significant difference. Conclusions: The efficacy of propacetamol is comparable to that of ketorolac in postoperative PCA with fentanyl.

• Journal of Fisheries and Marine Sciences Education
• /
• v.28 no.5
• /
• pp.1444-1458
• /
• 2016

The expansion of high-density aquaculture in the limited waters has caused a wide variety of problems. The problems include environmental problems nearby aquaculture sites, growth rate of aquatic organisms, quality decline of farmed fish and price fall in the market. The phenomenon of aquaculture industry happens in not only inshore but also offshore. Therefore, the fisheries authorities have been changing their policy paradigms from mass production to sustainable production based on ecosystem. Other countries, however, focusing on relieving poverty and providing protein from fish production have not recognized the degree of seriousness. When it comes to enhancing the problems, National Institute of Fisheries Science has been developing the technology of Integrated Multi-Trophic Aquaculture (IMTA) to reduce and to prevent contaminants from fish and aquaculture sites, remained feed from fish farming process. In long-terms of view, the system is one of the most sustainable fishery production methods based on ecosystem. As integration of nutrient feed system from aquatic organisms is firmly established, the earlier mentioned problems will be diminished gradually. In term of the substantiality, this study was conducted. The research on management system for IMTA also has been incorporated. This study also investigated the features and current status of IMTA and demonstrated the developed management system and direction for the future advancement.

• Food Science of Animal Resources
• /
• v.36 no.3
• /
• pp.405-411
• /
• 2016

The effects of gaseous ozone exposure on the bacterial counts and oxidative properties were evaluated in duck and chicken breast fillets, which were stored under a continuous flux of gaseous ozone (10×10⁻⁶ kg O₃/m³/h) at 4±1℃ for 4 d. The ozone generator was set to on for 15 min and off for 105 min, and this cyclic timer was set during storage. Ozone effectively reduced the growth of coliform, aerobic and anaerobic bacteria in both chicken and duck breast. However, lipid oxidation occurred faster in duck breast than chicken breast with higher degree of discoloration, TBARS value, and antioxidant enzyme (glutathione peroxidase and catalase) activity decline rates. It is concluded that ozone effectively controlled the growth of bacteria in both chicken and duck breast with less effects on oxidative deterioration in chicken breast.