• Asian Pacific Journal of Cancer Prevention
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• v.16 no.3
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• pp.1117-1122
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• 2015

Background: Cisplatin is still used as a first-line medication for solid tumors. Nephrotoxicity is a serious side effect that can decrease renal function and restrict applicable doses. This research aimed to obtain the profile of cisplatin-induced nephrotoxicity and its associated factors in adult cancer patients at Dharmais National Cancer Hospital (DNCH). Materials and Methods: The design was cross-sectional with data obtained from patient medical records. We retrospectively reviewed adult cancer patients treated with cisplatin ${\geq}60mg/m^2$ for at least four consecutive chemotherapy cycles from August 2011 to November 2013. The nephrotoxicity criterion was renal function decline characterized by creatinine clearance <60 ml/min using the Cockroft-Gault (CG) equation. Results: Eighty-eight subjects received at least four chemotherapy cycles of cisplatin. The prevalence of cisplatin nephrotoxicity was 34.1%. Symptoms could be observed after the first cycle of chemotherapy, and the degree of renal impairment was higher with increased numbers of cycles (r=-0.946, $r^2=89.5%$). Factors that affected the decline of renal function were patient age (p=0.008, OR=3.433, 95%CI= 1.363-8.645) and hypertension (p=0.026, OR=2.931, 95%CI=1.120-7.670). Conclusions: Cisplatin nephrotoxicity occurred in more than one-third of patients after the fourth cycle of chemotherapy and worsened after each cycle despite preventive strategies such as hydration. The decline of renal function induced by cisplatin ${\geq}60mg/m^2$ was affected by age and hypertension.

• PNF and Movement
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• v.10 no.2
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• pp.1-8
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• 2012

Purpose : The purpose of study was aimed to identify whether the painless dynamic PNF techniques makes any differences in reducing lymphedema by applying this technique to lymphedema patients, and to provide the basic reference data for the purpose of applying to lymphedema patients. Methods : A total of 40 women participated in this study, and they did PNF techniques before applying lymph compression bandages. Group 1 of 20 subjects performed PNF techniques three times a week with 30 minutes each time. Group 2 of 20 subjects only practiced edema reducing massaging for 30 minutes. Results : In addition, the interaction between treatment method and treatment time was significant (p<.0001), which indicates that the changes in edema rates by measurement times appear differently according to treatment methods. In this study, it means that the 'PNF techniques' group has a steeper slope of decline than the 'message' group. Conclusion : In conclusion, both massaging and PNF techniques helped to lower edema rates. Four weeks after the beginning of treatment, PNF techniques was exhibited as generating a large degree of decline in edema rates than massaging.

• Journal of Labour Economics
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• v.34 no.2
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• pp.1-27
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• 2011

This paper analyzes the demand and supply structure of the market for college professors, and then characterizes the changes in the economic status of them for the last three decades. On the supply side, the number of Korean recipients of doctorate degrees from the U.S. institutions, relative to the number of newly hired professors, has declined dramatically since early 1990s. The relative remuneration of professors, which is found to be closely related to the 'number of students per professor', has also declined steadily. These suggest that the decline in the relative wage of professors has been a driving force for the decline in the relative size of new PhD's in the U.S.

• KDI Journal of Economic Policy
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• v.37 no.1
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• pp.19-44
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• 2015

This paper examines the effect of the global financial crisis on corporate investment in Korea. Specifically, the crisis was considered to have possibly constrained firm-level investment as the negative shock to the credit supply dramatically unfolded. As Duchin et al. (2010) demonstrated, if a negative supply-side shock is evident during a crisis period, larger cash holdings before the crisis will lead to fewer constraints to corporate investment, or vice versa. In order to investigate the supply-side effect of the crisis, we use firm-level financial data, including firms listed on the Korean stock market as well as small and medium-sized enterprises. We find that corporate investment declined significantly after the crisis, even if we control for factors associated with the demand side, such as contemporaneous capital productivity and cash flow. More importantly, the decline is positively and significantly related to cash holdings before the crisis, implying the negative effect of a credit supply shock. Small and medium enterprises experienced relatively sharp investment declines compared to those of larger firms, and the relationship between pre-crisis cash amounts and the degree of investment decline is greater than that in large firms. Additionally, we examine whether the negative effect persists up to the present, finding evidence that the cash-investment relationship continues in small and medium-sized enterprises.

• The Journal of Pediatrics of Korean Medicine
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• v.26 no.4
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• pp.77-83
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• 2012

Objectives: The purpose of this study was to assess the effect of Extravascular Laser System on Osgood-Schlatter Disease Methods: In this study, we treated the 6 cases of children who were diagnosed with Osgood-Schlatter disease with Extravascular Laser System. 4 of them were treated with acupuncture as well, the other 2 were given with combined acupuncture and Blood-pricking Treatment. For evaluation, 6 children explained the degree of pain relief by comparing with degree of pain before treatment. Results: Extravascular Laser System for Osgood-Schlatter Disease resulted in a significant decline in the subjective pain degree. All of them were almost cured. The average treatment times was 6.7 times, and the average treatment period was 26.7days. Conclusions We report the good result of the efficacy of extravascular laser system on Osgood-Schlatter Desease. Cases in this study, however, were small in number. Therefore more study is required.

• Journal of Engineering Education Research
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• v.27 no.1
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• pp.3-12
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• 2024

The degree-linked programs for employees, operated by joint training centers in specialized universities that have implemented work-study integrated programs, are educational programs that require an annual government budget of around 80 billion KRW. However, the 70+ universities running these programs face issues such as a decline in academic achievement and an increase in dropout rates among students. In this paper, I conducted multiple regression analysis based on observed and measured information to examine whether the participating students in these programs are achieving an appropriate level of academic performance and to identify the factors that universities need to invest in to achieve that level. To do this, I hypothesized a causal relationship between the university's input factors and students' academic achievement, and used the SPSS program to analyze the statistical data, confirming the validity of the hypothesis. The collected data for the study were obtained through a survey developed using a Likert 4-point scale, which quantified the distribution of grades among students enrolled in IT-related departments offering the degree-linked programs for employees and the emotional contact efforts made by the universities to motivate them for academic success. Particularly, through the results of multiple regression analysis, it was confirmed that these input factors, unlike those for students in general education programs, require more personalized and frequent interactions.

• Analyses & Alternatives
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• v.2 no.2
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• pp.143-162
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• 2018

This paper focuses on the policy framework about "Quantitative and Qualitative Easing (QQE)" of Japan, and analyzes reasons why the policy goal was not reached. The QQE was introduced by the Bank of Japan in 2013 with the purpose of meeting the price stability target of 2% and getting out of deflation that prevents sustained price decline. However, despite the implementation of the bold monetary easing policy unprecedented in the world, the policy goal was not achieved as of June 2018. As a result of analyzing the causes, the following three structural factors were confirmed. 1) The rise in prices by QQE was limited because Japan's consumer price is strongly depending on import price. 2) The effect is high degree of uncertainty and limited because theoretical framework of reflationist which adopted QQE depends on "expectation formation" by "self-fulfilling expectation" and "multiple equilibria". 3) It was confirmed that the expansion of the monetary base did not lead to money stock due to the existence of Japanese liquidity trap, long-term low interest rate policy.

• 한국태양에너지학회:학술대회논문집
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• 2011.11a
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• pp.333-337
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• 2011

Central control air-conditioning systems are being replaced with individually controlled air-conditioning system in the university. The amount of growth of electricity consumption is due to the increasing demand of electric heat pump. In winter and summer, the energy consumption showed a tendency to increase. On the other hand, showed less energy in spring and autumn. Increase the amount of electricity than the degree of decline in gas consumption was higher. Can be considered as transitional phenomena. Because electric heat pump, gas driven heat pump and the absorption chiller-heater are used at the same time in some of the buildings.

• Proceedings of the Korean Society of Near Infrared Spectroscopy Conference
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• 2001.06a
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• pp.1158-1158
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• 2001

Fast and dynamic biochemical, enzymatic and morphological changes occur during the so-called generative development and during the vegetative processes in seeds. The most characteristic biochemical and compositional changes of this period are the formation and decline of storage components or their precursors, the change of their degree in polymerization and an extensive change in water content. The aim of the present study was to detect the maturation processes in seed nondestructively and to verify the applicability of near infrared spectroscopic methods in the measurement of physiological, chemical and biochemical changes in wheat seed. The amount and variation of different water “species” has been changed intensively during maturation. Characteristic changes of three water absorption bands (1920, 1420 and 1150 nm) during maturation were analysed. It was concluded that the free/bound transition of water molecules could be followed sensitively in different region of NIR spectra. Kinetic changes of carbohydrate reserves were characteristic during maturation. An intensive formation and decline of carbohydrate reserves were observed during early stage of maturation (0 -13 days, high energy demand). An accelerated formation of storage carbohydrates (starch) was detected in the second phase of maturation. Five characteristic absorption bands were analysed which were sensitive indicators the changes of carbohydrates occurred during maturation. Precursors of protein synthesis and the synthesis of reserve proteins and their kinetic changes during maturation were followed from NIR spectra qualitative and qualitatively. Dynamic formation of amino acids and the changes of N forms were detected by spectroscopic, chromatographic and by capillary electrophoresis methods. Calibration equations were developed and validated in order to measure the optimal maturation time protein and moisture content of developing wheat seeds. The spectroscopic methods are offering chance and measurement potential in order to detect fine details of physiological processes. The spectra have many hidden details, which can help to understand the biochemical background of processes.

• Journal of the Korean Society of Environmental Restoration Technology
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• v.23 no.6
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• pp.15-28
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• 2020

Urbanization and industrialization have caused increasing damage to national lands, and ecological restoration has proceeded without any specific assessment of this damage. The purpose of this study is to select indices to assess damaged areas through literature review and panel discussions, and to derive the importance of damaged area assessment indices by analyzing them through the Analytic Hierarchy Process (AHP). This study has derived, via literature review, six types of damage and a total of 18 related assessment indices. A total of 51 responses were collected from surveys and given to experts, and an AHP analysis conducted. As a result of the analysis, "Landform change (0.268)" was of the highest importance, with associated damage types as follows: "Soil contamination (0.193)", "Vegetation damaged (0.149)", "Surface soil loss (0.143)", "Change in soil physiochemical property (0.125)", and "Vegetation decline (0.122)". The analysis determined that the item of the highest importance in the overall assessment of damage was "Slope occurred area (0.100)", and that "Conductivity (0.022)" was of the lowest importance. This study can be presented as a criterion in determining the type and degree of damage in setting priorities for future ecological restoration projects.