• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.25 no.5
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• pp.607-617
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• 2014

This paper proposed the M&S(Modeling & Simulation) method of channel characterization of satellite communication in the operating area of satellite OTM(On-The-Move) terminal. In M&S, received signal profile was acquired by HTZ warfare software which uses 3 dimensional map including building, road information and geographical features, and then was analyzed statistically. And a received signal profile and its statistics from M&S data were compared with those from measured data. The research showed that the simulated received signal profile matched the measured one about 74.8 percent and simulated statistics matched well as roadside trees were excluded.

• Journal of the Korea Society of Computer and Information
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• v.25 no.9
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• pp.71-80
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• 2020

As societies become hyperconnected, we need more cyber security experts. To this end, in this paper, based on the analysis results of the real world cyber attacks and the MITRE ATT&CK framework, we developed CyTEA that can model cyber threats and generate simulated cyber threats in a cyber security training system. In order to confirm whether the simulated cyber threat has the effectiveness of the actual cyber threat level, the simulation level was examined based on procedural, environmental, and consequential similarities. in addition, it was confirmed that the actual defense training using cyber simulation threats is the same as the expected defense training when using real cyber threats in the cyber security training system.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.43 no.12
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• pp.1089-1096
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• 2015

A marine helicopter should remain sufficiently upright to permit safe evacuation of all personnel with a flotation system. And the rule requires that after ditching in water, the adequate flotation time will allow the occupants to leave the rotorcraft. To this end, stability test of the emergency flotation system for Korean marine helicopter was performed by using "Froude scaling method" in water tank. Test configuration and conditions were determined in consideration of the helicopter loading condition and related specifications. Test results meet the stability requirements at sea state code 4 and sea state code 2 with puncture conditions.

• International Journal of Oral Biology
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• v.33 no.4
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• pp.125-129
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• 2008

Inositol 1,4,5-trisphosphate ($IP_3$) plays an important role in the release of $Ca^{2+}$ from intracellular stores into the cytoplasm in a variety of cell types. $IP_3$ translocation dynamics have been studied in response to many types of cell signals. However, the dynamics of cytosolic $IP_3$ in salivary acinar cells are unclear. A green fluorescent protein (GFP)-tagged pleckstrin homology domain (PHD) was constructed and introduced into a phospholipase C ${\delta}1$ (PLC ${\delta}1$) transgenic mouse, and then the salivary acinar cells were isolated. GFP-PHD was heterogeneously localized at the plasma membrane and intracellular organelles in submandibular gland and parotid gland cells. Application of trypsin, a G protein-coupled receptor activator, to the two types of cells caused an increase in GFP fluorescence in the cell cytoplasm. The observed time course of trypsin-evoked $IP_3$ movement in acinar cells was independent of cell polarity, and the fluorescent label showed an immediate increase throughout the cells. These results suggest that GFP-PHD in many tissues of transgenic mice, including non-cultured primary cells, can be used as a model for examination of $IP_3$ intracellular dynamics.

• Journal of Korean Society for Quality Management
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• v.44 no.4
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• pp.785-798
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• 2016

Purpose: This paper developed the framework for extracting strategies of research and business development (R&BD) based on the data envelopment analysis(DEA). Methods: DEA has been widely utilized in evaluating R&D efficiency. Even though, technology transfer and commercialization has been regarded as the important factors for practical R&D efficiency evaluation, most research have evaluated R&D efficiency by just using the DEA outputs such as the number of patents and papers. The technology transfer, commercialization and relations among costs and generated technology and commercialization are needed to be considered for more practical R&D efficiency evaluation. Thus, this research addressed a method on how to incorporate the commercialization factors into the R&DB efficiency evaluation, and improve the efficiency strategically in terms of R&D and B&D. To achieve this, this research utilized a two-stage network DEA model for R&BD efficiency evaluation. Results: The proposed framework was applied to the 15 public research institutes and the 34 universities for validation. R&BD efficiency for the 15 public research institutes and the 34 universities was evaluated, and the differentiated improvement strategies for the inefficient DMUs to improve their efficient were proposed. Conclusion: The R&BD efficiency would be effectively analyzed based on two-stage network DEA. It would be utilized for the effective strategy planning for cultivating R&BD.

• Journal of the Korean Society of Propulsion Engineers
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• v.20 no.6
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• pp.29-37
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• 2016

This paper proposes a shape optimization of the metal boss for a composite motor case using finite element analysis. For the structural safety and the weight reduction of the composite motor case, under the internal pressure, the fiber stress in the dome area and the tightening bolt stress are constrained and the boss weight is set to objective function, respectively. The response surface models are constructed for the performance characteristics by using response surface method. The significance of the design variables about the performance characteristics is evaluated through the ANOVA(analysis of variance) and the goodness of fit test for the constructed model is performed through the regression analysis. The SQP(sequential quadratic programming) algorithm is used for the optimization and the proposed method is verified by performing structural analysis for the optimum shape.

• YAKHAK HOEJI
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• v.60 no.2
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• pp.92-99
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• 2016

Parkinson's disease (PD) is one of the representative neurodegenerative movement disorders with the selective loss of dopaminergic neurons in the substantia nigra. 6-Hydroxydopamine (6-OHDA) is widely used as an experimental model system to mimic PD and has been reported to cause neuronal cell death via oxidative and/or nitrosative stress. Therefore, daily intake of dietary or medicinal plants which fortifies cellular antioxidant capacity can exert neuroprotective effects in PD. In the present study, we have investigated the protective effect of Korean red ginseng (KRG) against 6-OHDA-induced nitrosative death in C6 glioma cells. Treatment of C6 cells with 6-OHDA decreased cell viability and increased expression of inducible nitric oxide synthase, production of nitric oxide as well as peroxynitrite, and formation of nitrotyrosine. 6-OHDA led to apoptotic cell death as determined by decreased Bcl-2/Bax, phosphorylation of JNK, activation of caspase-3, and cleavage of PARP. Conversely, pretreatment of C6 cells with KRG attenuated 6-ODHA-induced cytotoxicity, apoptosis, and nitrosative damages. To further elucidate the molecular mechanism of KRG protection against 6-OHDA-induced nitrosative cell death, we have focused on the cellular self-defense molecules against exogenous noxious stimuli. KRG treatment up-regulated heme oxygenase-1 (HO-1), a key antioxidant enzyme essential for cellular defense against oxidative and/or nitrosative stress via activation of Nrf2. Taken together, these findings suggest KRG may have preventive and/or therapeutic potentials for the management of PD.

• Convergence Security Journal
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• v.13 no.1
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• pp.37-43
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• 2013

In 2010, the Ministry of National Defense decided to build a MegaCenter including the cloud computing technology by 2014, as part of the '2012 Information Service Plan', which is now underway. The Cloud computing system environment should be designed applying cloud computing technology and policy for an efficient infrastructure that many IT resources are available in the data center as a concentrated form. That is, the system should be designed in such a way that clouding services will be efficiently provided to meet the needs of users and there will not be unnecessary waste of resources. However, in order to build an optimal system, it should be possible to predict the service performance and the resource availability at the initial phase of system design. In this paper, using the CloudAnalyst simulator to predict availability of the K-defence cloud computing system service, conducts cloud modeling and analysis of the 'Facebook', one of the most famous social network service applications with most users in the world. An Optimal K-Defense cloud computing design model is proposed through simulation results.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.42 no.3
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• pp.661-672
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• 2017

This paper introduces the NLSE(Nonlinear Least Squared Estimator) using curved LOBs(Line Of Bearings) considering the earth curvature based on sphere to avoid the map conversion distortion and minimize the estimation error. This paper suggests a method improving a performance of the NLSE using curved LOBs by using an ellipsoid model. The analysis of the simulation results shows that the NLSE using curved LOBs has better performance than the conventional triangulation method and can improve its performance using a suggested method.

• Journal of the Korea Institute of Military Science and Technology
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• v.22 no.6
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• pp.745-753
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• 2019

Recently, with the development of long-range / high-altitude guided weapon system for defense against ballistic missile, test range and firing altitude for guided weapons are increasing. Due to the increase in the test range and the intercepting altitude, it is expected to increase the range of safety area required for the firing test. Comparing to the foreign countries which have many desert or non-residence, in the domestic circumstances where the population is concentrated and distributed, it is more important to predict the falling area and to set the safety area for safely carry out the long-range / high-altitude intercept test. In this paper, we consider the following three points. The first is the booster fall trajectory modeling, the second is the shroud fall trajectory modeling, and finally, the debris dispersion modeling for the missile intercept. Especially, the AUTODYN model was used to predict debris falling area which produced in the high-speed guided missile intercepting test.