• 대한수의학회지
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• 제24권1호
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• pp.120-125
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• 1984

The study was carried out to find out the changes of hormone levels in blood serum and milk of Holstein cows during the estrous cycle. The progesterone, estradiol-$17{\beta}$ from the blood serum and milk samples were assayed by radioimmunoassay methods. The results of this study were summarized as follows; 1. The progesterone levels in blood serum during the estrous cycles began to decline rapidly at 2 days before estrus, decreased to $0.27{\pm}0.18ng/ml$ at on the day of estrus, and reached a peak mean level of $3.33{\pm}0.47ng/ml$ at 15 days after estrus. 2. The progesterone levels in milk during the estrous cycles began to decline rapidly at 2 days before estrus, decreased to $0.80{\pm}0.18ng/ml$ on the day of estrus, and increased a peak mean level of $3.80{\pm}0.36ng/ml$ at 15 days after estrus. 3. The estradiol-$17{\beta}$ levels in blood serum during the estrous cycles showed a peak mean level of $9.79{\pm}1.72pg/ml$ on the day of estrus, and decreased from $4.79{\pm}1.82pg/ml$ to $5.73{\pm}0.96pg/ml$ at luteal phase. 4. The estradiol-$17{\beta}$ levels in milk during the estrous cycles showed a peak mean level of $36.80{\pm}2.04pg/ml$ on the day of estrus, and decreased from $18.93{\pm}0.84pg/ml$ to $19.50{\pm}1.12pg/ml$ at luteal phase. 5. During 20 to 25 days after artificial insemination, the accuracy of pregnancy diagnosis from the blood serum progesterone levels were 87.5% for non pregnant cows (<2.0ng/ml), and 83.3% for pregnant cows ($${\geq_-}$$3.0 ng/ml). The accuracy of pregnancy diagnosis from the milk progesterone levels were 75.0% for non-pregnant cows (<2.4 ng/ml), and 94.4% for pregnant cows ($${\geq_-}$$3.2 ng/ml).

• 동의신경정신과학회지
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• 제32권3호
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• pp.285-302
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• 2021

Objectives: To examine the effect of long-term Korean medicine treatment on mild cognitive impairment (MCI). Methods: This study was conducted on two patients who were diagnosed with mild cognitive impairment and received long-term Korean medicine treatment. In order to evaluate the degree of cognitive decline, SNSB and K-MMSE were performed 2~3 times at the first visit and during the treatment process. Results: Both cases 1 and 2 were diagnosed with MCI with a high possibility of developing dementia. In case 1, MCI progressed to early dementia at one year after the diagnosis of MCI. However, in case 2, that MCI status was maintained without progressing to dementia for 4 years after the diagnosis of MCI. The cause of such difference in the course of MCI might be attributed to the fact that Case 1 had lower K-IADL level but higher SGDS level than Case 2 at the time of initial diagnosis, with weak family support and irregular herbal medicine intake. Conclusions: Korean medicine treatment could improve and manage symptoms of cognitive decline due to MCI.

• 한국정보처리학회:학술대회논문집
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• 한국정보처리학회 2012년도 춘계학술발표대회
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• pp.1302-1305
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• 2012

본 연구의 선행 연구에서는 시군구단위 도시쇠퇴를 진단할 수 있는 시스템을 개발하였다. 본 연구에서는 시군구 단위보다 더 세밀한 읍명동 단위 및 지구단위의 도시쇠퇴 현황을 파악할 수 있는 시스템을 개발하였다. 개발된 지구단위 쇠퇴진단 모듈을 기존의 도시재생 종합정보시스템과 통합하여 도시의 세밀한 쇠퇴현황을 파악할 수 있게 하였다. 개발된 시스템은 중앙정부차원의 도시재생 사업 의사결정 담당자뿐만 아니라 지자체의 도시재생 사업 담당자들이 사업을 계획하고 우선순위 대상지를 선정하는 업무 등에 활용 가능할 것으로 판단된다.

• Journal of the Optical Society of Korea
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• 제18권1호
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• pp.55-59
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• 2014

Sarcopenia, or reduced muscle mass and volume, is due to various factors such as senile change, neuronal degeneration, drug, malignancy, and sepsis. Sarcopenia with the aging process has been evidenced by the decline in muscle mass by 0.5 to 1% per year with 3-5% reduction in muscle strength for 10 years between the ages of 40 and 50, and a 1-2% of decline of mass every year in people aged 60-70. Therefore, early diagnosis and understanding the mechanism of sarcopenia are crucial in the prevention of muscle loss. However, it is still difficult to image changes of muscle microstructure due to a lack of techniques. In this study, we developed an animal model using denervated rats to induce a rapid atrophy in the tibialis anterior (TA) and imaged its structural changes using optical coherence tomography (OCT) along with histologic and ultrasound analyses. Ultrasound showed changes of overall muscle size. Histology revealed that the atrophic TA muscle displayed an increased size variability of muscle fiber and inflammatory changes. Three dimensional OCT imaged the changes of perimysial grid and muscle fiber structure in real time without sacrifice. These observed advantages of multimodal imaging using OCT and ultrasound would provide clinical benefits in the diagnosis of sarcopenia.

• 대한핵의학회지
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• 제38권3호
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• pp.209-217
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• 2004

Evaluation of dementia in patients with early symptoms of cognitive decline is clinically challenging, but the need for early, accurate diagnosis has become more crucial, since several medication for the treatment of mild to moderate Alzheimer' disease are available. Many neurodegenerative diseases produce significant brain function alteration even when structural imaging (CT or MRI) reveal no specific abnormalities. The role of PET and SPECT brain imaging in the initial assessment and differential diagnosis of dementia is beginning to evolve vapidly and growing evidence indicates that appropriate incorporation of PET into the clinical work up can improve diagnostic and prognostic accuracy with respect to Alzheimer's disease, the most common cause of dementia in the geriatric population. in the fast few years, studios comparing neuropathologic examination with PET have established reliable and consistent accuracy for diagnostic evaluations using PET - accuracies substantially exceeding those of comparable studies of diagnostic value of SPECT or of both modalities assessed side by side, or of clinical evaluations done without nuclear imaging. This review deals the role of functional brain imaging techniques in the evaluation of dementias and the role of nuclear neuroimaging in the early detection and diagnosis of Alzheimer's disease.

• 지역연구
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• 제37권4호
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• pp.33-47
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• 2021

도시 쇠퇴지역은 인구가 감소하고, 건축물과 시설물 등 건조환경은 노후화되고 있다. 따라서 재난·재해 발생 시 취약하며, 복구에도 많은 시간과 비용이 소요된다. 본 연구의 목적은 쇠퇴지역의 재난·재해를 종합적으로 진단하기 위한 평가기법을 개발하고 사례분석을 통해 시사점을 제시하는 것이다. 재난·재해 종합진단지수를 산출하기 위한 평가지표를 선정하고, AHP 분석으로 유형, 구성요소, 평가지표를 포함한 계층별 가중치를 산정하였다. 산정된 가중치로 유형별 종합진단지수를 산출하고, 도시쇠퇴 수준에 따른 위험성을 분석하였다. 서울시를 사례지역으로 분석한 결과 서초구, 동작구, 금천구, 강서구 등 남부지역에서 재난·재해 종합 위험도가 높고, 서울시 도심지와 북부지역 그리고 공원 및 녹지지역에서 상대적으로 낮은 것으로 분석되었다. 본 연구의 결과는 자연재난과 사회재난을 포함해 재난·재해 유형별 종합진단지수 평가체계와 기법을 제시한 점에서 학술적 의의가 있다.

• 생물정신의학
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• 제23권2호
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• pp.48-56
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• 2016

Alzheimer's disease (AD) is a neurodegenerative disorder in which neuronal loss causes cognitive decline and other neuropsychiatric problems. It can be diagnosed based on history, examination, and appropriate objective assessments, using standard criteria such as the Diagnostic and Statistical Manual of Mental Disorders or the National Institute of Neurological and Communicative Disorders and Stroke and the Alzheimer's Disease and Related Disorders Association (NINCDS-ADRDA). Brain imaging and biomarkers are making progress in the differential diagnoses among the different disorders. The cholinesterase inhibitors, donepezil, rivastigmine and galantamine and N-methyl-D-aspartate receptors antagonist memantine are approved by the US Food and Drug Administration for AD. Recently some acetylcholinesterase inhibitors gained approval for the treatment of severe AD and became available in a higher dose formulation or a patch formulation. Optimal care in AD is multifactorial and it should include early diagnosis and multidisciplinary care with pharmacological and nonpharmacological interventions including exercise interventions, cognitive interventions and maintenance of social networks.

• 대한방사성의약품학회지
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• 제8권2호
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• pp.103-111
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• 2022

Idiopathic pulmonary fibrosis (IPF) is a progressive disease caused by some risk factors, including smoking, viral infection, toxic substances, and radiation, that decline lung function of fresh oxygen and blood delivery throughout the body. Patients with pulmonary fibrosis have suffered from breathing and cough and the average survival rate is only 3 years after diagnosis. Therefore, it is significant to diagnose IPF and start treatment in enough time. Usually, lung biopsy is available to diagnose localized pulmonary fibrotic sites directly. However, it is insufficient to visualize whole lung tissue, and also it has a risk of infection for patients. In the clinic, medical imaging systems can diagnose pulmonary fibrosis non-invasively without infection. In this review, we introduce current medical imaging systems used to diagnose pulmonary fibrosis, including CT, MRI, and nuclear medicine. Further, we introduce several molecular imaging probes targeting specific biomarkers which are expressed in pulmonary fibrosis. Through this paper, it is expected that it would be helpful to understand the latest knowledge and research trends on pulmonary fibrosis diagnostic imaging.

• 한국문헌정보학회지
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• 제54권2호
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• pp.127-154
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• 2020

본 연구는 한국 대학사회에서 4차 산업혁명 시대의 도래 및 대학 입학자원의 급감에 대비해야 할 필요성을 인식하고, 현 국내 문헌정보학과의 현황을 진단하였으며, 이에 대응하기 위한 향후 문헌정보학과의 정체성 및 미래 발전 방향을 모색하였다. 연구결과, 2020년 2월을 기준으로 우리나라에 문헌정보학과가 설치된 대학은 총36개교(2년제 4곳, 4년제 32곳)이며, 학부과정이 폐과된 대학은 총8개교(2년제 5곳, 4년제 3곳)이고, (교육)대학원이 폐과된 곳은 총10개교인 것으로 밝혀졌다. 또한 2013년과 대비하여 2019년에 입학 정원수는 38.5%가 감소하였으며, 전임교원수도 13.4%가 감소한 것으로 확인되었다. 따라서 앞으로 한국의 문헌정보학과의 정체성 및 미래 발전 방향을 크게 5가지로 구분하여 첫째, 학문 정체성 차원에서 융합교육 필요, 둘째, 법·국가차원에서 문헌정보학과 진흥 및 사서 취업 안정성 보장, 셋째, 협회차원에서 문헌정보학과에 대한 사회적 이미지 제고, 넷째, 대학차원에서 문헌정보학과 지원 및 홍보 확대, 다섯째, 학과차원에서 학생중심 교육강화 및 취업률 향상을 도모할 것을 제안하였다.

• 스마트미디어저널
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• 제12권9호
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• pp.28-37
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• 2023

쌀 수확량 감소에 크게 영향을 주는 것은 집중호우나 태풍에 의한 도복 피해이다. 도복 피해 면적 산정 방법은 직접 피해 지역을 방문하는 현장 조사를 기반으로 육안 검사 및 판단하여 객관적인 결과 획득이 어렵고 많은 시간과 비용이 요구된다. 본 논문에서는 무인 항공기로 촬영된 RGB 영상을 Vision Transformer 기반 Segformer을 활용한 벼 도복 영역 추정 및 진단을 제안한다. 제안된 방법은 도복, 정상, 그리고 배경 영역을 추정하고 종자관리요강 내 벼 포장 검사를 통해 도복률을 진단한다. 진단된 결과를 통해 벼 도복 피해 분포를 관찰할 수 있게 하며, 정부 보급종 포장 검사에 활용할 수 있다. 본 연구의 벼 도복 영역 추정 성능은 평균 정확도 98.33%와 mIoU 96.79%의 성능을 나타내었다.