• 융합정보논문지
• /
• 제7권6호
• /
• pp.135-141
• /
• 2017

최근 만성질환을 앓고 있는 고령자가 늘어나고 교통사고와 같은 재난이 증대됨에 따라 이와 같은 응급상황에 응급구조사와 의사들이 효율적으로 대응할 필요성이 대두되고 있다. 특히, 만성질환과 치매를 앓고 있던 고령자에게 뇌경색이나 교통사고와 같은 응급상황이 발생하게 되면, 기본적인 자신의 인적정보과 병력을 전달하지 못하여 구조대의 응급처치가 늦어지고 의료정보의 부족으로 병원에서의 효율적인 응급치료도 어렵게 된다. 본 논문에서는 QR 코드를 이용하여 응급 구조사에게는 응급치료에 필요한 최소한의 개인정보와 병력을 전달하고 병원의 응급실 의사에게는 QR 코드와 지문인식을 통해 그동안의 병력 및 치료데이터를 전달함으로써 효율적인 응급처치 및 응급치료가 가능하도록 하였다. 특히 스마트폰의 QR 코드와 개인의 지문을 동시에 활용함으로써 개인정보는 보호하고 권한을 부여받은 의사들만이 병적기록을 확인할 수 있도록 하여 의료정보의 프라이버시 및 보안을 강화했다.

• 한국멀티미디어학회논문지
• /
• 제25권8호
• /
• pp.1212-1223
• /
• 2022

Skin lesions are common diseases that range from skin rashes to skin cancer, which can lead to death. Note that early diagnosis of skin diseases can be important because early diagnosis of skin diseases considerably can reduce the course of treatment and the harmful effect of the disease. Recently, the development of computer-aided diagnosis (CAD) systems based on artificial intelligence has been actively made for the early diagnosis of skin diseases. In a typical CAD system, the accurate classification of skin lesion types is of great importance for improving the diagnosis performance. Motivated by this, we propose a novel deep ensemble classification with multi-scale attention networks. The proposed deep ensemble networks are jointly trained using a single loss function in an end-to-end manner. In addition, the proposed deep ensemble network is equipped with a multi-scale attention mechanism and segmentation information of the original skin input image, which improves the classification performance. To demonstrate our method, the publicly available human skin disease dataset (HAM 10000) and the private animal skin lesion dataset were used for the evaluation. Experiment results showed that the proposed methods can achieve 97.8% and 81% accuracy on each HAM10000 and animal skin lesion dataset. This research work would be useful for developing a more reliable CAD system which helps doctors early diagnose skin diseases.

• 한국식물병리학회:학술대회논문집
• /
• 한국식물병리학회 2003년도 정기총회 및 추계학술발표회
• /
• pp.13-13
• /
• 2003

When plants are infected by plant pathogens, rapid cell responses are initiated for further inhibition from fast invasion of pathogens. Hypersensitive response (HR) of plant is well known defense response stopping pathogenesis process through rapid cell death. However, informations on the signaling pathway from reception of pathogen by host plants to appropriate resistant responses are very limited to date. Efficient perception of infection by pathogens and well-programmed signalling mechanism for appropriate responses are important for survival of plants. Plant have developed a sophisticated network(s) of defense/stress responses, among which one of the earliest signalling pathways after perception (of stimuli) is the evolutionary conserved Rop GTPase and mitogen-activated protein kinase (MAPK) cascade.(중략)

• Journal of Chest Surgery
• /
• 제9권2호
• /
• pp.148-156
• /
• 1976

Acute respiratory failure has become an increasingly frequent cause of death following shock or trauma. Interstitial or diffuse alveolar edema, as chief pathophysiologic change of acute respiratory insufficiency, can be the result of sepsis, fat embolism, cardiac failure, lung congestion, and oxygen toxicity. These pulmonary problems are extremely difficult to treat without early recognition of their development and aggressive management. If the treatment is delayed, the progressive respiratory failure is almost uniformly fatal. Authors have experienced two cases of acute respiratory insufficiency following the blunt chest trauma, which were healed uneventfully. Literatures were briefly reviewed.

• Neonatal Medicine
• /
• 제16권1호
• /
• pp.18-24
• /
• 2009

Seizures are the most common clinical symptom of a neurologic insult and have long been recognized as an obvious marker of brain dysfunction in newborns. Presence of seizures in newborn infants may signify substantial risk for subsequent neurodevelopmental impairment including postneonatal epilepsy and death. The outcomes of seizures in neonates are determined mainly by the etiology of the seizures. Despite the decreasing trend of mortality of neonatal seizures, the prevalence of long-term neurodevelopmental sequelae in survivors has remained unchanged over time. Clinical studies have contributed to identifying significant prognostic factors for neurodevelopmental outcome. The underlying etiology of the seizures and electroencepaphalography background pattern are considered as most reliable early predictors of later neurologic sequelae. However, clinicians managing neonatal seizures are still challenged by difficult therapeutic and prognostic questions because of many unresolved issues in seizure recognition, terminology, relationships to the underlying brain lesion, effect of current management, particularly antiepileptic drugs on long-term outcomes. This review presents the prognosis of neonatal seizures, especially about mortality and neurodevelopmental deficit, and predictors of outcomes.

• 보건행정학회지
• /
• 제28권3호
• /
• pp.308-314
• /
• 2018

Injury is a serious problem that not only causes death but also significantly degrades the quality of life of the people and causes loss of socioeconomic opportunities and costs. Damage occurs as a result of an accident. Among them, natural disasters and artificial disasters take lives of many people in a short time and threaten their physical and mental health. The United States has responded to the disaster by establishing relevant laws and regulations and a response system with the recognition that health is recognised soon to be as national security in the wake of the 9/11 terrorist attacks and the Katrina disaster. It is necessary to build a knowledge infrastructure to train disaster response experts in public health area and to have health competence to cope with disasters.

• Bulletin of the Korean Chemical Society
• /
• 제23권7호
• /
• pp.1003-1010
• /
• 2002

Caspase 3, a member of cysteine protease family, is well known as a major apoptosis effector and is involved in cell death as a result of ischemic diseases such as stroke and myocardial infarction, therefore the inhibition of caspase 3 may protect those apoptotic cell damages. During the high-throughput screening of the compounds from the Korea Chemical Bank, berberine derivatives (A and B), an isoquinoline alkaloid, have been identified as potential inhibitors for caspase 3. Based on this finding we carried out molecular modeling study to identify the pharmacophoric elements of berberine structure which interact with a substrate-recognition binding site of caspase 3 and came up with several novel scaffolds. In this report, we will discuss the molecular modeling, syntheses and the enzyme inhibitory activities of these novel compounds.

• Journal of Korean Neurosurgical Society
• /
• 제65권3호
• /
• pp.397-407
• /
• 2022

Abusive head trauma (AHT) is the most common and serious form of child abuse and a leading cause of traumatic death in infants and young children. The biomechanics of head injuries include violent shaking, blunt impact, or a combination of both. Neuroimaging plays an important role in recognizing and distinguishing abusive injuries from lesions from accidental trauma or other causes, because clinical presentation and medical history are often nonspecific and ambiguous in this age group. Understanding common imaging features of AHT can increase recognition with high specificity for AHT. In this review, we discuss the biomechanics of AHT, imaging features of AHT, and other conditions that mimic AHT.

• Annals of Occupational and Environmental Medicine
• /
• 제34권
• /
• pp.30.1-30.13
• /
• 2022

Background: Although working hours have decreased in Korea, they are still high compared to that of other countries. In Korea, cardiovascular and cerebrovascular diseases (CCVDs) related to overwork in Korea continually occur, and the social burden from overwork is estimated to be high. This study investigated the amendment of regulations affecting the approval rate of occupational CCVDs. Methods: The change in approval rate of occupational CCVDs and related regulations were investigated using the Act and public notice on the standards for recognition of occupational CCVDs and the yearbooks of the Ministry of Employment and Labor. The CCVD mortality was estimated using data on the number of deaths according to the cause of death, the number of employed people, and resident registration population aged 15-64 years. The cumulative mortality of CCVDs was estimated using the Kaplan-Meier method. Results: Since the establishment of the standards for recognition in Korea in 1982, the scope of occupational diseases has been expanded to include intracerebral hemorrhage, subarachnoid hemorrhage, cerebral infarction, myocardial infarction, and aortic dissection. In 2013, the concept of working hours was introduced in chronic overwork. The approval rate of occupational CCVDs was 44.7% in 2006, which decreased to 12.9% in 2011. After the improvement of related regulations, the approval rate increased to 41.3% in 2018. From 2000 to 2017, the CCVD mortality of both the unemployed and employed tended to decrease, and their cumulative CCVD mortalities were 549.3 and 319.7 per 100,000 people, respectively. Conclusions: CCVDs are recognized as occupational diseases in Korea. The amendments to the standards for recognition, the introduction of the Occupational Disease Adjudication Committee, the principle of presumption, and the reduction of working hours have changed the approval rate of occupational CCVDs. A strategic approach is needed to further reduce the incidence of CCVDs.

• 고전문학과교육
• /
• 제33호
• /
• pp.153-184
• /
• 2016

본고는 묵재 이문건(1494-1567)이 어머니 고령 신씨(高靈申氏; 1463-1535)의 시묘살이를 하며 기록한 상례(喪禮)에 대한 고찰이다. 상례는 죽음에 대한 의례이다. 이문건이 행한 죽음의례, 즉 시묘살이 상례(喪禮)에 개인이 어떻게 구체적으로 참여하였는가에 초점을 두어 살펴보았다. 즉 이문건이 실천한 시묘살이 상례의 특징을 살펴봄으로써 그 의례가 지향하는 바의 의미와 조선중기 사대부 일기의 글쓰기를 통해 당대인의 효의 실천과 죽음에 대한 제반 인식을 유추해보는 데 그 의의를 둔다. 조선중기 사대부들은 법제화에 의한 상례 준수로 인식변화를 끊임없이 시도하지만, 기나긴 역사의 밑바탕에 깔린 인간의 의식세계를 완전히 개조하기는 현실적으로 어려웠다. 중국과 조선은 문화적 배경이 달랐음을 인정해야만 하였다. 중국의 제도인 "주자가례"를 조선에 끼워 맞추려고 한 것은 처음부터 문제를 배태하고 있는 것이다. 신주(神主) 중심의 조상 제사와 가묘(家廟) 설립의 중요성을 "주자가례"에서 백 번 강조하지만, 조선중기 사대부는 무덤 속에 누워 있는 부모에게 더 마음이 가는 것이다. 사당과 시제(時祭)보다는 무덤과 묘제(墓祭) 및 기제사(忌祭祀)가 조선중기의 사대부에게는 더 중요한 것이다. 이런 모순 속에서 조선중기 사대부는 죽음에 대한 의례로서 시묘살이 상례를 수용하고 실천하였다. 고대인 혹은 중세인이 아니라도 현재를 살아가는 우리 인간에게 죽음에 대한 지배적 생각, 즉 현세와 정신적 물질적 생활을 지속한다는 계세사상(繼世思想)을 뿌리 채 뽑아버리기는 쉽지 않아 보인다. 만약 이 사상이 없다면 인간의 죽음 역시 고속도로 위에서 차에 치여진 동물의 사체와 다름이 없기 때문이다. 그래서 인간은 시간이 변해도 형태는 바뀔지언정 죽음에 대한 의례 자체를 끊임없이 생각하지 않을 수 없는 것이다. 그러므로 조선중기 사대부의 시묘살이는 효의 실천과 죽음에 대한 의례로 시사하는 바가 크다고 하겠다.