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Mechanical Dilation of the Recipient Vessel with the DeBakey Vascular Dilator in Lower Extremity Reconstruction: A Report of Two Cases

  • Min-Gi Seo;Tae-Gon Kim
    • Archives of Plastic Surgery
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    • v.50 no.3
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    • pp.311-314
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    • 2023
  • In lower extremity reconstruction, the recipient vessel often requires long-range mechanical dilation because of extensive vasospasm or plaque formation induced by concomitant atherosclerosis. While a forceps dilator can be used to manipulate and dilate vessels approximately 1 cm from their end, a DeBakey vascular dilator can dilate long-range vessels. The authors successfully performed free flap reconstruction of the lower extremity using the DeBakey vascular dilator. Of the two patients who underwent lower extremity reconstruction, one had extensive vasospasm, and the other had plaques in the recipient arteries. Irrigation with 4% lidocaine and dilation of the lumen with a forceps dilator were insufficient to restore the normal arterial blood flow. Instead, a DeBakey vascular dilator with a 1-mm diameter tip was gently inserted into the lumen. Then, to overcome vessel resistance, the dilator gently advanced approximately 10 cm to dilate the recipient artery. Normal arterial blood flow was gushed out after dilating the vessel lumen using a DeBakey vascular dilator. The vascular anastomosis was performed, and intravenous heparin 5000 IU was administered immediately after anastomosis. Prophylactic low-molecular-weight-heparin (Clexane, 1 mg/kg) was administered subcutaneously to both patients for 14 days. The reconstructed flap survived without necrosis in either patient.

FABRICATION AND CHARACTERIZATION OF NONLINEAR OPTICAL GLASSES

  • Cardinal, T.;Fargin, E.;Le Flem, G.
    • Proceedings of the Optical Society of Korea Conference
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    • 2001.02a
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    • pp.4-5
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    • 2001
  • Advent of lasers offering high intensity beam has opened the glass to the nonlinear optic (NLO). The high electric field associated with such laser beams can be so large that high order components of the glass polarization can be measured. Such development is of scientific and technological interests in particular in systems involving an intensity-dependent refractive index and/or ultra-fast response (<10$\^$-12/s). From a scientific viewpoint the NLO response intensity must be understood as a function of the glass composition. On the other hand, large family of applications are presently under investigation in various fields of optical materials or systems e.g. laser glasses for fusion energy, soliton propagation for ultra-long distances, ultra-fast-switching, optical storage etc....(omitted)

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Intrinsic bent DNA colocalizes with the sequence involved in the Nd-sD mutation in the Bombyx mori fibroin light chain gene

  • Barbosa, Joice Felipes;Bravo, Juliana Pereira;Takeda, Karen Izumi;Zanatta, Daniela Bertolini;Silva, Jose Luis Da Conceicao;Balani, Valerio Americo;Fiorini, Adriana;Fernandez, Maria Aparecida
    • BMB Reports
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    • v.41 no.5
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    • pp.394-399
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    • 2008
  • Multiple sequence alignments of the Bombyx mori fibroin light chain gene (fib-L) from hybrids and from Chinese and Japanese strains demonstrated that 51.6% of the fib-L third intron is conserved. One of these conserved segments, 41 bp long, contains the sequence CGTTATTATACATATT, which is duplicated in the B. mori Nd-$s^D$ mutant. In the present work, electrophoretic mobility assays and computational analyses revealed a major peak of intrinsic bent DNA within the segment that undergoes breakage in the previously-described Nd-$s^D$ mutation. This result suggested that this intrinsically-curved region might mediate DNA cleavage and enhance recombination events in the third intron of the Bombyx mori fib-L gene.

A home-based exercise program for temporomandibular joint osteoarthritis: pain, functionality, and joint structure

  • Macias-Hernandez, Salvador Israel;Morones-Alba, Juan Daniel;Tapia-Ferrusco, Irene;Velez-Gutierrez, Oscar Benjamin;Hernandez-Diaz, Cristina;Nava-Bringas, Tania Ines;Cruz-Medina, Eva;Toro, Lya Contreras-del;Soria-Bastida, Ma. de los Angeles
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.48 no.1
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    • pp.50-58
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    • 2022
  • Objectives: Osteoarthritis (OA) is the most prevalent and disabling joint disease in the world. Temporomandibular joint (TMJ) exercise is a widely used treatment and could be a beneficial and long-term tool for treating TMJ OA. The present study aims to evaluate the effects of therapeutic exercise in the conservative treatment of TMJ OA. Materials and Methods: A single-group experimental pre-post test was performed. We included patients who met the diagnostic criteria for TMJ OA. Outcome variables were pain intensity (visual analogue scale), functionality (Helkimo index), and structural changes (ultrasound). Follow-up periods were at months 1, 3, and 6. The intervention included a home-based program with thermotherapy, manual therapy, and therapeutic exercise during the entire follow-up period. Results: We included 15 patients and 26 joints, all women with a median age of 57 years (range, 49-62 years). Median change in pain intensity on joint palpation, mouth opening, and at rest at the first month was 47.5 mm, 51 mm, and 60 mm, respectively, and 48 mm, 49.5 mm, and 42.5 mm, at six months (P=0.001). The Helkimo index showed significant improvement in medians from baseline severe dysfunction (17 points) to minimal dysfunction at three and six months (2 points) (P=0.001). Ultrasound showed improved disc position. Conclusion: This study demonstrated significant improvements in pain, function, and joint disc position and represents a valuable tool for the long-term treatment of patients with TMJ OA.

Assessment of Near-Term Climate Prediction of DePreSys4 in East Asia (DePreSys4의 동아시아 근미래 기후예측 성능 평가)

  • Jung Choi;Seul-Hee Im;Seok-Woo Son;Kyung-On Boo;Johan Lee
    • Atmosphere
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    • v.33 no.4
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    • pp.355-365
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    • 2023
  • To proactively manage climate risk, near-term climate predictions on annual to decadal time scales are of great interest to various communities. This study evaluates the near-term climate prediction skills in East Asia with DePreSys4 retrospective decadal predictions. The model is initialized every November from 1960 to 2020, consisting of 61 initializations with ten ensemble members. The prediction skill is quantitatively evaluated using the deterministic and probabilistic metrics, particularly for annual mean near-surface temperature, land precipitation, and sea level pressure. The near-term climate predictions for May~September and November~March averages over the five years are also assessed. DePreSys4 successfully predicts the annual mean and the five-year mean near-surface temperatures in East Asia, as the long-term trend sourced from external radiative forcing is well reproduced. However, land precipitation predictions are statistically significant only in very limited sporadic regions. The sea level pressure predictions also show statistically significant skills only over the ocean due to the failure of predicting a long-term trend over the land.

Prediction of hysteretic energy demands in steel frames using vector-valued IMs

  • Bojorquez, Eden;Astorga, Laura;Reyes-Salazar, Alfredo;Teran-Gilmore, Amador;Velazquez, Juan;Bojorquez, Juan;Rivera, Luz
    • Steel and Composite Structures
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    • v.19 no.3
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    • pp.697-711
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    • 2015
  • It is well known the importance of considering hysteretic energy demands for the seismic assessment and design of structures. In such a way that it is necessary to establish new parameters of the earthquake ground motion potential able to predict energy demands in structures. In this paper, several alternative vector-valued ground motion intensity measures (IMs) are used to estimate hysteretic energy demands in steel framed buildings under long duration narrow-band ground motions. The vectors are based on the spectral acceleration at first mode of the structure Sa($T_1$) as first component. As the second component, IMs related to peak, integral and spectral shape parameters are selected. The aim of the study is to provide new parameters or vector-valued ground motion intensities with the capacity of predicting energy demands in structures. It is concluded that spectral-shape-based vector-valued IMs have the best relation with hysteretic energy demands in steel frames subjected to narrow-band earthquake ground motions.

Morphology control and optical properties of ZnO nanostructures grown by ultrasonic synthesis

  • Morales-Flores, N.;Galeazzi, R.;Rosendo, E.;Diaz1d, T.;Velumani, S.;Pal, U.
    • Advances in nano research
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    • v.1 no.1
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    • pp.59-70
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    • 2013
  • ZnO nanostructures of rod-like, faceted bar, cup-end bars, and spindle shaped morphologies could be grown by a low power ultrasonic synthesis process. pH of the reaction mixture seems to plays an important role for defining the final morphology of ZnO nanostructures. While the solution pH as low as 7 produces long, uniform rod-like nanostructures of mixed phase (ZnO and $Zn(OH)_2$), higher pH of the reaction mixture produces ZnO nanostructures of different morphologies in pure hexagonal wurtzite phase. pH of the reaction as high as 10 produces bar shaped uniform nanostructures with lower specific surface area and lower surface and lattice defects, reducing the defect emissions of ZnO in the visible region of their photoluminescence spectra.

Monitoring in a reinforced concrete structure for storing low and intermediate level radioactive waste. Lessons learnt after 25 years

  • Nuria Rebolledo;Julio Torres;Servando Chinchon-Paya;Javier Sanchez;Sylvia de Gregorio;Manuel Ordonez;Inmaculada Lopez
    • Nuclear Engineering and Technology
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    • v.55 no.4
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    • pp.1199-1209
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    • 2023
  • Where concrete structures are designed to have a service life of over 100 years, their performance must be monitored, for the prediction models available are fraught with uncertainties that need to be eliminated. The present study was conducted to meet that need by monitoring a pilot structure for low and intermediate radioactive waste storage. Long-term operation of the sensors was observed to be adequate to determine the value of the parameters that characterise structural durability, such as corrosion current density. The parameters analysed were correlated to calculate their reciprocal impact: where applied in conjunction with artificial intelligence tools, temperature, for instance, was found suitable for finding activation energy and expansion coefficients and detecting outliers. The results showed the pilot structure to perform satisfactorily.

Pain medication and long QT syndrome

  • Klivinyi, Christoph;Bornemann-Cimenti, Helmar
    • The Korean Journal of Pain
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    • v.31 no.1
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    • pp.3-9
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    • 2018
  • Long QT syndrome is a cardiac repolarization disorder and is associated with an increased risk of torsades de pointes. The acquired form is most often attributable to administration of specific medications and/or electrolyte imbalance. This review provides insights into the risk for QT prolongation associated with drugs frequently used in the treatment of chronic pain. In the field of pain medicine all the major drug classes (i.e. NSAIDs, opioids, anticonvulsive and antidepressant drugs, cannabinoids, muscle relaxants) contain agents that increase the risk of QT prolongation. Other substances, not used in the treatment of pain, such as proton pump inhibitors, antiemetics, and diuretics are also associated with long QT syndrome. When the possible benefits of therapy outweigh the associated risks, slow dose titration and electrocardiography monitoring are recommended.