• Archives of Plastic Surgery
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• 제41권6호
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• pp.647-653
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• 2014

Background Administration of growth factors has been associated with increased viability of composite grafts greater than 1-cm in diameter. Platelet-rich plasma (PRP) contains many of the growth factors studied. In this study, we evaluate the effect of PRP injection on composite graft viability and the proper time for injection. Methods A total of 24 New Zealand White rabbits were divided into four groups. Autologous PRP was injected into the recipient sites three days before grafting in group 1, on the day of grafting in group 2, and three days after grafting in group 3. Group 4 served as control without PRP administration. Auricular composite grafts of 3-cm diameter were harvested and grafted back into place after being rotated 180 degrees. Median graft viability and microvessel density were evaluated at day 21 of graft via macroscopic photographs and immunofluorescent staining, respectively. Results The median graft survival rate was 97.8% in group 1, 69.2% in group 2, 55.7% in group 3, and 40.8% in the control group. The median vessel counts were 34 (per ${\times}200$ HPF) in group 1, 24.5 in group 2, 19.5 in group 3, and 10.5 in the control group. Conclusions This study demonstrates that PRP administration is associated with increased composite graft viability. All experimental groups showed a significantly higher survival rate and microvessel density, compared with the control group. Pre-administration of PRP was followed by the highest graft survival rate and revascularization. PRP treatments are minimally invasive, fast, easily applicable, and inexpensive, and offer a potential clinical pathway to larger composite grafts.

• 한국지하수토양환경학회지:지하수토양환경
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• 제25권1호
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• pp.12-24
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• 2020

This study was conducted to examine an artificial recharge system, which was considered to be an alternative for securing additional groundwater resources in a high-density greenhouse region. An injection well with a depth of 14.0 m was placed in an alluvial plain of the zone. Eight monitoring wells were placed in a shape of dual circles around the injection well. Aquifer tests showed that the aquifer was comprised with high-permeable layer with hydraulic conductivities of 1.5×10^-3~2.4×10^-2 cm/sec and storage coefficients of 0.07~0.10. A step injection test resulted in a specific groundwater-level rising (Sr/Q) values of 0.013~0.018 day/㎡ with 64~92% injection efficiencies. Results of the constant-rate injection test with an optimal injection rate of 100 ㎥/day demonstrated an enormous storage capacity of the alluvial aquifer during ten experimental days. To design an optimal recharge system for an artificial recharge, the high-permeable layer should be isolated by dual packers and suitable pressure should be applied to the injection well in order to store water. An anisotropy ratio of the alluvial aquifer was evaluated to be approximately 1.25 : 1 with an anisotropy angle of 71 degrees, indicating intervals among injection wells are almost the same.

• 한국농공학회지
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• 제11권4호
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• pp.1827-1831
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• 1969

Resulties of research on the capacity of ground water of 994 concrete-pipe-wells and 97 infiltration-gallerys in ground-water-developement-works region executed from March to Julyin 1969, in Choong Chung Nam Do, and research on the quality of ground water for 88 wells for home-use around of River Geum Area, are as fellows: (1) Thickness of aquifer is no more than 2.85m averagely even at river-overflowed plain, alluvial plain and valley plain area that are estimated to contain ground water mostly. And so, it is guessed that ground water capacity is not much especially. (2) Soil of aquifer of the above area is sand or gravel and it is estimated to be good for ground water developement and its mean permeability coefficient is bout $2.5{\times}10^{-3}$(m/sec), and its porosity is about 33.9%. (3) The quality of ground water is good for irrigation water exception of delta plain area. Warm water plan is to need for irrigation water when water temperature is less than 19 degrees below zero. (4) Prospect of ground water developement, judging from quality and quantity, expects to lay infiltration gallery under the ground at river bed in order to utilize under-flow-water of river bed, river-overflowed plain, alluvial plain and valley plain that ground level is less than 50m. (5) Collectable water volume of under-flow-water of river bed is about 450 to $750m^3/day$ to be able to irrigate 3ha to 5ha of the cultivated land in case that infiltration gallery length is 50m and its depth is about 5m. (6) Collectable water volume at river-overflowed plain, alluvial plain and valley plain area, is estimated $150m^3/day$ to be able to irrigated 1ha of the cultivated land.

• Archives of Reconstructive Microsurgery
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• 제2권1호
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• pp.82-92
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• 1993

A comparative study was undertaken to evaluate the contact Neo-dymium : yttrium aluminum garnet(Nd:YAG) laser system for vascular anastomosis of small caliber blood vessels(diameter 0.5-1.2 mm) in the animal model. In this study 40 femoral arteries and 40 femoral veins of Sprague-Dawley rats were anastomosed by contact laser assisted microvascular anastomosis(LAMA) utilizing 3 stay sutures which were placed 120 degrees apart and the intervals welded with contact Nd:YAG laser unit, conventionally sutured anastomosis(CSA) served as controls. The time needed for vascular anastomosis, patency rate(immediate postoperative, postoperative 2nd day, postoperative 1 week, postoperative 4 weeks), gross and microscopic evaluations were compared to conventional microsurgical suture technique. The results are as follows: 1. Postoperative patency rate was 82.5% for femoral artery and 75% for femoral vein by contact LAMA technique compared to 90% and 75% by CSA technique at postoperative 4 weeks. 2. Less time-consumed for arterial anastomosis by 6 minutes 23 seconds and venous anastomosis by 8 minutes 55 seconds with contact LAMA technique compared to CSA technique. 3. Grossly almost complete healing had taken place by postoperative 1 week by contact LAMA technique. 4. Aneurysm formation was 5% for femoral artery and 15% for femoral vein by contact LAMA technique compared to 5% and 10% respectively by CSA technique. 5. Microscopically, re-endothelization was complete by postoperative 7th day by contact LAMA technique. There was less medial hypertrophy and hyperplasia and also less inflammatory response compared to CSA.

• 한국가금학회지
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• 제18권3호
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• pp.141-150
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• 1991

국내에서 분리된 CAA의 병아리에 대한 병원성시험과 야외계군에서의 CAA에 대한 항체 보유상황을 조사한 결과 다음과 같은 결론을 얻었다. 1. CAA국내 분리주 89-69를 감수성이 있는 1일령의 SPF병아리에 접종하였을 때 접종 14일 후 심한 빈혈과 흉선 및 Fabricius낭의 위축이 유발되었고 접종계 및 그 동거계에서 CAA가 재분리되었다. 2. CAA분리주 89-69를 유래가 다른 1일령의 SPF 두 계군의 병아리에 각각 근육접종하였을 때 두 계군간 CAA분리주에 대한 감수성의 차이를 보여 주었으며 이는 이 두 계군에서의 CAA에 대한 항체보유율과 관련이 있었다. 3. 간접형광항체반응 시험으로 야외계군에서의 CAA에 대한 항체보유상항을 조사한 결과 39계군중 29계군(74％)이 CAA에 대한 항체를 보유한 것으로 나타났으며 두 SPF계군중 한 SPF계군에서도 항체가 검출되었다.

• 대한한방내과학회지
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• 제38권5호
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• pp.698-708
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• 2017

Objectives: The aim of this study was to report the clinical effects of a combination of Gamiguibi-tang and sweet bee venom on a patient with Raynaud's disease. Methods: The patient with Raynaud's disease was treated with Gamiguibi-tang three times a day for 43 days and with sweet bee venom daily. The effects on Raynaud's disease were measured on both hands using a cold stress test and an infrared thermometer and by digital infrared thermographic imaging and a NRS (Numeric Rating Scale). We conducted the cold stress test at 6-8 day intervals from 2016.04.27 to 2016.06.08. Results: After treatment, the symptoms of pain were decreased in both hands and digital infrared thermographic imaging (DITI) confirmed a rise in the temperature of the fingers. The fingertip temperature increased from 29.6 to 30.4 degrees and the cooling/rewarming ratio (CRR) increased steadily. No adverse events were found at discharge. Conclusions: Gamiguibi-tang combined sweet bee venom may improve symptoms in patients with Raynaud's disease.

• 한국응용곤충학회지
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• 제36권1호
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• pp.43-47
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• 1997

담팔수(Elaeocarpus sylvestris va. ellipticus Hara)를 기주로 하여 담팔수깍지벌레(Protopulvinaria mangiferae (Green))의 발육속도 및 증식능력을 조사하였다. 본 깍지벌레의 1령약충기부터 산란전성충기까지 발육소요일수는 온도가 상승할수록 짧았으며, 발육한계온도는 11.7$^{\circ}C$, 유효적산온도는 1000.0일도 이었다. $25^{\circ}C$, $30^{\circ}C$ 항온, 60-70% RH조건하에서 부화율은 각 온도구 모두 99% 이상으로 높았다. 산란전성층까지의 생존율은 $25^{\circ}C$에서 82%, $30^{\circ}C$에서 60%이었으며, 1령약충(neonate crawler)기의 사망률이 가장 높았다. 성충체로부터 1령약충의 이탈기간은 $25^{\circ}C$에서 50일 $30^{\circ}C$에서 33일간 이었으며, 이 기간 중 총이탈약충수의 50%이상이 분산기간 초기에 발생되었다. 발육기간 및 영별생존율 및 출생수를 이용하여 산출한 순번식율(${R}_{o}$), 평균세대기(T) 및 내적자연증가율은(${r}_{m}$)은 $25^{\circ}C$에서 각 132.6, 76.2, 0.064/암컷/일로 $30^{\circ}C$구 보다 높았다.

• 대한간호학회지
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• 제38권1호
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• pp.140-151
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• 2008

Purpose: The purpose of this study was to understand the meanings and nature of living in the world among cancer patients. The present study adopted a hermeneutic phenomenological method which was developed by van Manen. Method: The participants for this study were 5 men and 6 women, who were over the age of 20 with admission or a follow up visit in the medical or surgical department. Data were collected by using in-depth interviews and observations from February to September, 2007. The contents of the interviews were tape-recorded with the consent of the subject. Result: The essential themes that fit into the context of the 4 existential grounds of body, time, space and other people were: a body that cannot be restored, a body that endures and lives, waiting in uncertainty, a valued calculation for the living day, being in a world of invisible power, reestablishing relationships, and reflection on his or her life. Conclusion: These findings revealed that living in the world is affected to varying degrees by the cancer. It is important for nurses to identify and take care of disabilities and to support the reorientation in the disintegrated life situation. The result of this study can give nurses some insight into these experiences and help promote empathetic care.

• 환경위생공학
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• 제18권4호
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• pp.64-69
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• 2003

Recently, Indoor air quality(IAQ) in workplace, residential environments and office has been concern of people, scientists and related the public. The oxygen in air was very important and essential element in every aspect of life. This study was performed on a questionnaire survey of 400 people about their awareness of indoor air quality, oxygen generators and measured of oxygen concentration in indoor environment. The results obtained were as follows; As respondents are having their 90% of daytime indoors a day, and 80% of them can feel indoor air pollutions degrees directly by particle matters. The control of most important problems of IAQ was the poor ventilation. We know that 22% of the respondents was recognized the oxgen generator. And for the installation of indoor pollution control equipment, 20% of all respondents installed oxygen generators because almost respondents was not satified the trust of ability purified indoor air pollutants. In the experimental results, it was found that the oxygen concentration of sampling sites were in the range of 20~23.5%. Therefore, it was recommended that the government related IAQ was suggested the guideline and control of oxygen generators. Finally, it appeared that the oxygen generators using indoor environment can be applied to new technology for cleaning of indoor air.

• 대한의용생체공학회:의공학회지
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• 제29권2호
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• pp.114-121
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• 2008

Within 2 to 5 months after stroke, patients recover variable degrees of function, depending on the initial deficit. An impaired hand function is one of the most serious disability in chronic stroke patients. Therefore, to evaluate the extent of motor dysfunction in the hemiplegic hand is important in stroke rehabilitation. In this paper, motor recoveries in 8 chronic stroke patients with Fugl-Meyer (FM) and white matter changes before and after the training program with a designed bilateral symmetrical arm trainer (BSAT) system were examined. The training was performed at 1 hr/day, 5 days/week during 6weeks. In all patients, FM was significantly improved after the 6-week training. Diffusion tensor imaging (DTI) results showed that tractional anisotropy ratio (FAR) and fiber tracking ratio (FTR) in the posterior internal capsule were significantly increased after the training. It seemed that the cortical reorganization was induced by the 6 week training with the BSAT. In all parameters proposed this study, a significant correlation was found between these parameters (FAR and FTR) and motor recoveries. This study demonstrated that DTI technique could be useful in predicting motor recovery in chronic hemiparetic patients.