• 스마트미디어저널
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• 제12권11호
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• pp.95-102
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• 2023

Road accidents not only caused loss of human lives but also costed 3% of gross domestic product in most of the countries. The road accidents pose significant challenges to public safety and urban transportation management. There is a need to identify the high-risk area of accidents along with the critical day of week and vulnerable time period in order to implement effective preventive measures and optimizing the resource allocation. We collected 5,012 accident data from 대구교통종합정보. This study identified the high-risk locations, days of week, and time periods for accidents in Daegu and estimated the conditional probabilities of accidents occurring based on combinations of location, day of the week, and time period. The result is visualized in the form of dashboard in Tableau. This study holds substantial practical significance for urban planners, transportation authorities, and policymakers in Daegu to strategically allocate resources for traffic management, law enforcement, and targeted safety campaigns.

• Toxicological Research
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• 제15권1호
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• pp.9-17
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• 1999

This study was performed to evaluate the subacute toxicity of CJ-50002 (Vibrio Vaccine) in SPF Spraqur-Dawley (SD) rats. Vibrio vaccine was administered orally at a dose level of high (167mg/kg/day), medium (16.7mg/kg/day), and low (16.7mg/kg/day) once a day and repeated fro 4 weeks. Ten males and female rats were assigned to each group. After 4 week administration, no significant dose-dependent changes in body weight, water and food consumption rate or organ weight were noted dependent changes in body weight, water and food consumption rate or organ weight were noted among 4 groups. Urinanalysis, hematology, and serum chemistry, also fail to detect any dose-related change among 4 groups tested. During necropsy and histopathological examination, no specific toxicity related to treated material was found. The result of this study demonstrated that vibrio vaccine when administered orally for 4 weeks at a high dose of 167mg/kg/day, no dose-related toxicity was found in treated make and female rats.

• 대한물리치료과학회지
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• 제19권4호
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• pp.7-15
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• 2012

Background : The purpose of this study is to determine the effect Berg Balance Scale(BBS) evaluating frequency on the walking speed and dynamic balance control in patient with stroke. Method : sixteen patient with stroke were randomly allocated to an experimental and control group of eight patients each. For the experimental group, we performed both general physical therapy and BBS and general physical therapy only for the control group. The general physical therapy programs for the 2 group were conducted for 1 hour 1 a day, 5 times a week for 4 weeks, and BBS for the experimental group was conducted for 1 time a week. Result : A comparison of the Berg Balance Scale(BBS). Timed Up Go test(TUG) and 10 meter Walking Test(10mWT) score obtained before and after the 4-week treatment revealed statistical significant different(p<.05) for the experimental group. BBS evaluated weekly and the first day and the last day evaluated in both groups after 4 weeks of BBS assessment improved significantly were (p<.05) especially in the assessment group on a weekly basis more improvement was. BBS weekly assessment group and the first day and on the last day, a group evaluation after 4 weeks in both the change of the TUG, 10mWT was significantly improved in the evaluation group(p<.05). Conclusion : 1 time a week of the BBS assessment of with stroke patients BBS, TUG, 10mWT that can help to improve. especially on a weekly basis, more has been improved.

• 대한기관식도과학회지
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• 제5권2호
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• pp.164-173
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• 1999

Background : cis-Diamminedichloroplatinum(Ⅱ)(cis-platin) has been exhibited similar to bifunctional alkylating agents in the cell and known as an effective anticancer drug. Although this agent is very beneficial to the cancer patients, it may also damage to the normal cell. Many side effects were developed. Objectives : This experiments was undertaken to pursue the effect of cis-Platin on the mucous variation of the trachea. Materials and Methods : The male of Sprague-Dawley strain were used as and experimental animals. The experimental animals were killed at 1, 3 days and 1, 2 and 3 weeks after the third injection of cis-Platin was administered 1.5mg/kg to intraperitoneal injection at once a week for three weeks. The trachea was fixed to neutral formaline and stained with alcian blue(pH 1.0)-PAS, alcian blue(pH 2.5)-PAS double stains and these preparation observed with light microscope. Results : 1. In the trachea stained with alcian blue(pH 2.5)-PAS double stain, the epithelial cells were constricted in the 1 week, In the 1st day, 3rd day and 1st week, acidic mucopolysaccharide was increased but in the 2nd week, neutral mucopolysaccharide was increase. 2. In the trachea stained with alcian blue(pH 1.0)-PAS double stain, the 1st and 3rd day exhibited sulfa mucopolysaccharide with moderately or weakly positive reaction. In the 1st week the sulfa mucopolysaccharide with strongly positive reaction was increased. In the 2nd and 3rd week, the sulfa mucopolysaccharide with weakly positive and non-sulfa or neutral mucopolsaccharide with negative reaction were modified. Conclusion : It is consequently suggested that cis-Platin induces reversible toxic damage to tracheal cells including goblet cell.

• Fisheries and Aquatic Sciences
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• 제16권1호
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• pp.57-61
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• 2013

I hypothesized that the manipulation of dietary nutrient contents including phosphorous could affect compensatory growth of juvenile olive flounder, Paralichthys olivaceus. Thirty fish averaging 34.8 g per tank were randomly chosen and distributed into 15 flow-through 180-L tanks. Three experimental diets were prepared: the control (C) diet, high protein and lipid (HPL) diet, and HPL diet with supplementation of calcium phosphate-monobasic (HPLP). Five treatments were prepared in triplicate: fish were hand-fed daily with the C diet twice a day for 8 weeks (C-8W); fish were starved for 1 week, and then fed with the HPL or HPLP diets twice a day for 7 weeks, and referred to as HPL-7W and HPLP-7W, respectively; and fish were starved for 2 weeks, and then fed with the HPL or HPLP diets twice a day for 6 weeks, and referred to as HPL-6W and HPLP-6W, respectively. The body weight of fish with C-8W, HPL-7W and HPLP-7W treatments was higher than fish with HPL-6W and HPLP-6W treatments on week 2, 4 and 6 after an initiation of the trial. At the end of the 8-week trial, fish with HPLP-7W and HPL-7W treatments overcompensated, as compared to fish with C-8W treatment. Full compensation was not achieved in fish subjected to the 2-week feed deprivation (HPL-6W and HPLP-6W treatments). Overall feed intake by fish was proportional to weeks of feeding. Feed conversion ratio of fish with HPLP-7W, HPL-6W and HPLP-6W treatments was higher than fish with C-8W treatment. The study showed that dietary supplementation of protein and lipid resulted in overcompensation of juvenile olive flounder subjected to a 1-week feed deprivation, but not a 2-week feed deprivation. Additionally, dietary supplementation of phosphorous did not further improve compensatory growth of fish.

• 대한한방소아과학회지
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• 제15권2호
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• pp.31-41
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• 2001

We studied 100 neonates to enter a Dongguk University Oriental Hospital Postpartum Care Center, during 9 months from February 10. 2001 to November 4. 2001. The conclusion is following. 1. Newborn sex ratio was 1.70. 2. Delivery method : Normal vaginal delivery was 66 and cesarean section was 34. 3. Gestation age : Premature infants less than 37 weeks were 2 term infants from 37 to 41 weeks were 98 and post-term infants 42 or more weeks were zero. 4. Period between birth and admission : First to fifth day was 66 sixth to tenth day was 32 and eleventh or more day was 2. 5. Period of admission : 1 to 7 days were 8. 8 to 14 days were 65. 15 to 21 days were 23. and 22 to 28 days were 4. 6. Weight : Birth weight less than 2500g was 3. 2500 to 3999g was 92. and 4000g or more was 5. 7. Height : Zero week after birth the average height was 48.8cm, one week after birth was 50.0cm, two weeks after birth was 51.8cm, three weeks after birth was 53.2cm, four weeks after birth was 54.5cm. 8. Head circumference : Zero week after birth the average head circumference was 34.6cm, one week after birth was 35.3cm, two weeks after birth was 35.7cm, three weeks after birth was 36.3cm, four weeks after birth was 36.8cm. 9. Chest circumference : Zero week after birth the average chest circumference was 33.2cm, one week after birth was 33.5cm, two weeks after birth was 34.4cm, three weeks after birth was 35.1cm, four weeks after birth was 36.6cm. 10. Feeding : There was not breast feeding, artificial feeding was 8, and mixing feeding was 92. 11. Jaundice : Physiologic jaundice was 10, pathologic jaundice was 1.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제20권4호
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• pp.341-354
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• 1998

GMI (Fibrel${(R)}$) is one of the dermal filling substances which have been successfully used for the treatment of depressed cutaneous scar and wrinkles. It's major components are; Gelatin powder, which provides a framework for the clot to form and remains stable under the scar, and ${\varepsilon}$-aminocaproic acid, which inhibits the production of fibrinolysin, and Plasma, which provides the necessary ingredients for collagen synthesis. GMI has advantages of low immunogenicity and increased longevity. It has been known to induce fibroblast activity and promote new collagen synthesis. We used 34 Sprague-Dawley rats which were bred under the same condition and duration. 18 of experimental animals were undergone cardiac puncture, and their blood were collected, centrifugated, and stored in freezer. Out of 16 animals, control group were injected with 2ml plasma into the subcutaneous tissue of Lt. scapular, while experimental group were implanted of 2 ml GMI into the Rt. same area. Experimental animals were sacrificed at the 3rd day, 5th day, 1st week and 2nd week respectively after implantation of GMI. To observe the histopathologic change of GMI and surrounding tissue reaction of GMI, we had examined with H&E staining, immunohistochemical staining with vimentin, ${\alpha}$-SMA, S-100 under LM and SEM. The obtained results were as follows ; 1. In LM study, the inflammatory cell infiltrations and granulation tissue formation were observed, and muscle tissues were well attached with adipose tissues in the control group. In the experimental group, inflammatory cell infiltrations had been observed by the 2nd week and irregular adipiose tissues and well differentiated mesenchymal tissues were examined. 2. In immunohistochemical study, the experimental group of ${\alpha}$-SMA study, there were a prominent positive response on endothelial development of granulation tissues and mesenchymal tissues compare with the control group. In vimentin study, positive response on mescenchymal fibroblast continued to 2nd week, but negative in the control group. In S-100 study, both groups were positively responded on irregular adipose tissues. 3. In SEM study, collagen fibers were embedded by the plasma by the 5th day in the control group, and in the 3rd day experiment GMI were resorved but communited with collagen fiber till the 1st week. Collagen fibers were infilt-rated into GMI at the 2nd week and the infilltrated GMI were conglomerated with the mature adipose cells and the collagen fibers. From the above results, GMI implantation in the subcutaneous tissue of Sprague-Dawley rat, the mild infiltration of inflammatory cells were showed till 2nd week and the granulation tissues were observed. GMI were nearly resorbed till 2nd week, but well attached with adipose tissue and collagen fibers. The endothelium and fibroblasts were actively proliferated. Adipose tissues and mesenchymal tissue cells were observed. As already expressed, GMI showed resorptive change in course of time without any early immune reaction, and seemed to induce fibroblast activity and promote new collagen synthesis.

• 생물환경조절학회지
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• 제11권4호
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• pp.205-216
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• 2002

본 실험은 정식 후 단일처리전 장일처리 기간에 따른 온실재배 스프레이 절화국 (cv. Reagan Improved)의 생육 및 건물생산에 미치는 영향을 구명하기 위하여 네덜란드 Wageningen 대학의 유리온실 실험포에서 수행하였다. 정식에서 개화기까지 3주 장일처리구에서는 84일이었고, 2주 처리구에서는 77일, 1주 처리구에서는 70일,단일처리 후에 최종수확일까지는 63일이 소요되었다. 정식 후 초장 생장량은 3주 장일처리구에서 가장 높았고, 1주 장일처리구에서 가장 낮았다. 또한 정식 후 최종 엽수, 엽면적 확보량 및 엽생체중과 총식물생체중은 3주 장일처리구에서 높고, 1주 장일처리구에서 낮은 결과를 나타내었다. 반면.단일처리 후 절대생장율에 있어서 엽전개속도와 초장생장속도는 모든 처리구에서 동일한 반응을 보였다. 최종건물생산량 (g.m$^{-2}$ )은 3주 장일처리구에서 높고, 1주 장일처리구에서 가장 낮게 나타났다. 초장과 생체중은 장일 조건이 길수록 높게 나타났으며,누적 건물중도 3주 장일처리구에서 가장 높은 결과를 나타냈다.

• 대한지역사회영양학회:학술대회논문집
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• 대한지역사회영양학회 2004년도 춘계학술대회
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• pp.434.2-435
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• 2004

본 연구는 마우스에 있어 규칙적인 수영훈련과 비타민 C 섭취가 운동스트레스를 부여하였을 때 항산화체계에 미치는 영향을 보고자 하였다. 수영훈련은 6주령의 Balb/c 마우스를 분양받아 1주간의 환경적응과 1주간의 수영적응 훈련을 (30 min/day) (5d/week) 실시하여 적응 여부를 가려 8주간의 본 수영훈련을 실시하였다(1 h/day) (5d/week). 실험군은 통제군(control: C), 수영훈련시킨 군(training: T), 수영훈련과 비타민 C를 투여한 군(training ＋ vitamin C (1.3 g/100 g diet) : TC}으로 나누었다.(중략)

• Journal of Nutrition and Health
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• 제17권4호
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• pp.273-280
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• 1984

The blood components of diabetic patients who visited S- hospital in seoul from January 1982 to June 1983 were compared with the reference levels. Hemoglobin and hematocrit levels of diabetic patients were significantly lower than the reference. The diabetic patients showed 2-3 times higher levels of fasting blood glucose and postprandial -2 hours blood sugar. Levels of blood urine nitrogen and creatine were also significantly higher in the diabetes mellitus and the levels of potassium sodium and chlorine showed no differences although these were decreased gradually in older patients. Lower serum calcium levels were seen in the diabetic patients and this change was more significant at the ages higher than 40. The effect of an active vitamin D on serum-Ca level in diabetic patients was studied in comparison to that of non- diabetic persons. The serum calcium levels were slightly increased in control and insulin- dependent diabetic patients after a week- intake of 1,000mg calcium a day, while the intake of 1,25-dihydroxycholecalciferol ( 1,000 IU per day ) did not increase the serum calcium levels of these groups. Insulin - independent diabetic patients showed the rather lower serum calcium levels after a week- intake of 1,000mg calcium per day. However, the levels were increased after 2-weeks intake of the calcium and a week-in-take of the active vitamin D(1,000 IU/day ). This effect of vitamin D was seen in the groups with lower intake of calcium(500mg/day ) but not in the groups with 1,000mg calcium intake a day.