Purpose: The purpose of this study is to present a preferred parts list, establish a search tool for common parts, and propose a development plan for parts management. Methods: When selecting the preferred parts list, the weight of the selection of the military parts and the online site of the civilian parts were taken into account. By establishing a database of selected preferred parts list, we have established a system for searching common parts. Results: The results of this study are as follows; In order to establish parts management work in Korea's defense, it is necessary to improve the Defense Acquisition Program Act, Enforcement Decree (Rules), and the Regulations for Defense Acquisition Program Administration. Development of performance indicators for parts management is required, and establishment of procedures and standards for selection of preferred parts lists is required. Considerations for the selection of preferred parts list include whether they are used a lot in civilian products, whether they are used a lot, whether they are certified suppliers, whether they are national and industrial standard products, whether they perform well considering reliability, durability, and quality, and whether they can be supplied continuously. Conclusion: It is necessary to establish policies and systems related to parts management and to establish criteria for selecting preferred parts list for the development of domestic parts management tasks.
Objectives: To review and analyze clinical and preclinical evidence of effectiveness, safety, and underlying mechanisms of yokukansan (YKS), a herbal medicine, in alleviating aggression. Methods: Classical records on YKS were searched in the Korean Traditional Medicine Knowledge Database (KTMKD). By searching five electronic databases, prospective clinical studies and preclinical studies of YKS for alleviating aggression/agitation published up to March 30, 2021 were included. Results: Only two classical records on YKS were found from the KTMKD. A total of 11 clinical studies and 15 preclinical studies were found from the five electronic databases. Among 11 clinical studies, seven enrolled patients with dementia and four enrolled patients with other neuropsychiatric disorders. Most clinical studies reported significant improvement in one or more outcomes related to aggression in the YKS group after treatment. Among 15 preclinical studies, all studies except two reported a significant decrease in aggression/agitation-related behavior of YKS or yokukansankachimpihange. Suggested underlying mechanisms of YKS or yokukansankachimpihange for aggression/agitation in these studies included regulation of serotonin receptor, amelioration of abnormal glucocorticoid level related to the hypothalamic-pituitary-adrenal axis, regulation of orexin secretion, amelioration of degeneration in brain cells including glia cells, and suppression of excessive glutamatergic or dopaminergic activity. Conclusions: There were some clinical and preclinical evidence supporting the effectiveness and safety of YKS for alleviating aggression. Given that aggression is the most frequent and destructive symptoms of behavioral and psychological symptoms of dementia, applicability of YKS as a herbal medicine should be further investigated in future high-quality research.
The Journal of Churna Manual Medicine for Spine and Nerves
/
v.16
no.2
/
pp.97-105
/
2021
Objectives This study is aimed to evaluate cost-effectiveness of treatment of Korean Medicine for whiplash associated disorders (WAD) and to suggest the direction of future research. Methods We searched papers in Pubmed database to use some keywords indicating whiplash injury syndrome, treatment of Korean Medicine and cost-effectiveness. After searching, appropriate papers were selected depending on the exclusion criteria. The selected papers were analyzed in the sections of author, publication year, intervention and control groups, outcome measurement, the list including in the cost, cost-effectiveness, cost-utility and study design. Results Four studies about effect of Korean medicine and 3 studies about economic evaluation were finally included. Acupuncture was effective for balance disorder and neck pain. Economic evaluation studies used analytical decision model or cost-consequence analysis. Cost-effectiveness analysis using visual analog scale and cost-utility analysis using quality adjusted life years were performed. Initiating timing of proper management affected the consequence of treatments. Direct and indirect medical costs including supportive devices, and non-medical costs such as litigation were considered. Conclusions We conclude that studies haven't been conducted so far to evaluate the cost-effectiveness of Korean Medicine in whiplash injury syndrome. Thus, future studies are needed in this section.
Objective: This study aims to examine the effectiveness of miniscrew assisted rapid palatal expansion (MARPE) treatment in late adolescents and adult patients using cone-beam computed tomography (CBCT). Methods: Literature search was conducted in five electronic databases (PubMed, Embase, Scopus, Web of Science, and Cochrane Library) based on the PICOS keyword design focusing on MARPE. Out of the 18 CBCT screened outcomes, only nine parameters were sufficient for the quantitative meta-analysis. The parameters were classified into three main groups: 1) skeletal changes, 2) alveolar change, and 3) dental changes. Heterogeneity test, estimation of pooled means, publication bias, sensitivity analysis and risk of bias assessment were also performed. Results: Upon database searching, only 14 full-text articles were qualified from the 364 obtained results. Heterogeneity test indicated the use of the random-effects model. The pooled mean estimate were as follows: 1) Skeletal expansion: zygomatic width, 2.39 mm; nasal width, 2.68 mm; jugular width, 3.12 mm; and midpalatal suture at the posterior nasal spine and anterior nasal spine, 3.34 mm and 4.56 mm, respectively; 2) Alveolar molar width expansion, 4.80 mm; and 3) Dental expansion: inter-canine width, 3.96 mm; inter-premolar width, 4.99 mm and inter-molar width, 5.99 mm. The percentage of expansion demonstrated a skeletal expansion (PNS) of 55.76%, alveolar molar width expansion of 24.37% and dental expansion of 19.87%. Conclusions: In the coronal view, the skeletal and dental expansion created by MARPE was of the pyramidal pattern. MARPE could successfully expand the constricted maxilla in late adolescents and adult patients.
The aim of this systematic review was to evaluate clinical and microbiological outcomes with the use of azithromycin as an adjunct to non-surgical subgingival professional mechanical plaque removal (PMPR) in the treatment of grade C periodontitis. Online database searches using high-level MeSH terms in a PICO structure were conducted along with hand-searching of relevant periodontal journals. Titles and abstracts of identified studies were independently reviewed by both authors and the full texts of studies meeting the inclusion criteria were independently reviewed. In total, 122 studies were identified through searches, of which 6 were included in the qualitative analysis and 4 in the meta-analysis. Three studies included in the meta-analysis were deemed at low risk of bias and 1 at serious risk. There were conflicting results on whether azithromycin reduced the number of subgingival pathogens or detectable subgingival Aggregatibacter actinomycetemcomitans between the included studies. The meta-analysis revealed a statistically significant probing depth reduction difference in favour of azithromycin compared to the control at 3 months (weighted mean difference [WMD]=-0.39 mm; 95% confidence interval [CI], -0.66 to -0.13 mm; I2=0%) and 12 months (WMD=-1.32 mm; 95% CI, -1.71 to -0.93 mm; I2=0%). The clinical attachment level change was also statistically significant in favour of azithromycin compared to the control at 3 months (WMD=-0.61 mm; 95% CI, -1.13 to -0.10 mm; I2=71%) and 12 months (WMD=-0.88 mm; 95% CI, -1.32 to -0.44 mm; I2=0%). Based upon these results, azithromycin offers additional improvements in some clinical parameters when used in conjunction with subgingival PMPR in patients with aggressive periodontitis over control groups. These improvements appear to be maintained for up to 12 months after treatment completion. However, due to a lack of well-designed studies, the conclusions that can be drawn from the available evidence are limited.
Based on the light an exoplanet blocks from its host star as it passes in front of it during a transit, the mid-transit time can be determined. Periodic variations in mid-transit times can indicate another planet's gravitational influence. We investigate 83 transits of TrES-1 b as observed from 6-inch telescopes in the MicroObservatory robotic telescope network. The EXOTIC data reduction pipeline is used to process these transits, fit transit models to light curves, and calculate transit midpoints. This paper details the methodology for analyzing transit timing variations (TTVs) and using transit measurements to maintain ephemerides. The application of Lomb-Scargle period analysis for studying the plausibility of TTVs is explained. The analysis of the resultant TTVs from 46 transits from MicroObservatory and 47 transits from archival data in the Exoplanet Transit Database indicated the possible existence of other planets affecting the orbit of TrES-1 and improved the precision of the ephemeris by one order of magnitude. We now estimate the ephemeris to be (2 455 489.66026 BJDTDB ± 0.00044 d) + (3.0300689 ± 0.0000007) d × epoch. This analysis also demonstrates the role of small telescopes in making precise midtransit time measurements, which can be used to help maintain ephemerides and perform TTV analysis. The maintenance of ephemerides allows for an increased ability to optimize telescope time on large ground-based telescopes and space telescope missions.
Objectives This study was conducted to assess the effect of chuna manual therapy after hip arthroplasty. Methods We searched across 9 electronic databases (PubMed, Cochrane Library, Wangfang data, China National Knowledge Infrastructure [CNKI], Oriental Medicine Advanced Searching Integrated System [OASIS], National Digital Science Library [NDSL], Korean Medical Database [KMBASE], Koreanstudies Information Service System [KISS], Research Information Sharing Service [RISS]) to find randomized controlled clinical trials for chuna manual therapy after hip arthroplasty. Results On inclusion criteria, 11 appropriate studies were included and analyzed. The deep vein thrombosis incidence of the chuna manual therapy group was statistically lower than the conventional treatment group (p=0.0002). Chuna manual therapy significantly improved the Harris hip score compared with conventional treatment (p<0.00001). Also, chuna manual therapy combined with herbal fumigation therapy significantly elevated the hip joint function score of Harris hip score compared with the conventional therapy group (p<0.00001). Conclusions The systematic review showed that chuna manual therapy had significant effects on hip arthroplasty. Nonetheless, considering the high risk of bias and geographic bias, further research with well-designed studies is required to support the effectiveness of chuna manual therapy.
Background Pain in the postoperative body contouring patient has traditionally been managed with narcotic medication. In an effort to minimize side effects and prevent addiction, plastic surgeons are searching for novel ways to provide adequate analgesia, one of which is nerve blocks. This study was conducted with a meta-analysis that evaluates the efficacy of these blocks for patients who undergo breast surgery. Methods A search of the PubMed/MEDLINE database for articles including the terms "post-operative analgesia" OR "postoperative pain management" AND "in plastic surgery" OR "in cosmetic surgery" OR "in elective surgery" in February 2019 generated five studies on elective breast augmentation and reduction mammoplasty that reported pain scores and quantities of opioids consumed. Independent samples t-tests, one-way analysis of variance, and a random effects model were implemented for evaluation. Results A total of 317 patients were identified as having undergone body contouring of the breast, about half of which received a nerve block. Pain scores on a 1-10 scale and opioid dose-equivalents were calculated. Those who were blocked had an average score of 2.40 compared to 3.64 for those who did not (P<0.001), and required an average of 5.20 less narcotic doses (P<0.001). Pain relief following subpectoral augmentation was best achieved with type-II blocks as opposed to type-I and type-II with serratus plane (P<0.001). Conclusions The opioid epidemic has extended to all surgical specialties. Implementation of a nerve block seems to be an efficacious and cost-effective mechanism to not only help with post-operative pain, but also lower the need for narcotics, especially in subpectoral augmentation.
Objectives : A precise and simple system of nomenclature was required to avoid error, ambiguity or confusion. Although medicinal plants must be produced or distributed based on a pharmacopoeia described origin including scientific name, the Korean Pharmacopoeia tenth edition (KP 10) had many names against the nomenclature. Therefore, this study aimed at searching correct scientific names for 241 plants in KP 10. Methods : Authoritative databases - The Plant List, International Plant Name Index, YList, Tropicos, eFloras, World Checklist of Selected Plant Families, The Global Compositae Checklist, The International Legume Database and Information Service, et al. - and previously performed researches, floras were cross-checked. Results : The arrangement of this list was designed for four cases, errors including illegitimate, nomenclatural synonyms, recommended names and decision reserved names. Consideration about the scientific names produced nine correct names for ten misspellings and illegitimate, and thirty-six correct names for forty-one nomenclatural synonyms. These results should be reflected in the next of KP 10. Separately, ten recommended names were also suggested for taxonomic synonyms which had been used indiscriminately due to diverse taxonomic opinions. In addition to those, decision reserved names were suggested for thirteen species which had been corridor of uncertainty. Then again, there was need to study about authorship, because KP 10 did not keep recommendations for author citations. Conclusions : Correction of scientific names for some medicinal plants which violated the International Code of Nomenclature would be useful to improve the accuracy of a Pharmacopoeia as the criterional materials.
The purpose of this study is to analyze the trends of MZ generation's lifestyle-related research from 2010 to 2020. As a result of searching keywords such as MZ generation's and lifestyle using academic database search sites, a total of 218 cases were used as analysis data to conduct frequency and content analysis. First, research type was 74 dissertations(34.6%), 144 journals(65.4%). The study of MZ generation was relatively active in journals. Second, the current status of academic field was 85(39.7%) in the social field, followed by 66(30.8%) in the arts/physical education, 21(9.8%) in the complex studies, 16(7.5%) in education, 15(7.0%) in nature, 6(2.8%) in engineering, 4(1.9%) in humanities, 1(0.5%) in agriculture/marine. Third, the current status of MZ generation research topics is 54 social participations(25.3%), 35 fashion/beauty(16.3%), 31 social/organizational adaptations(14.5%), 25 cultural/leisure activities(11.7%), 24 design/development projects(11.2%), 21 economic/employment/job projects(9.8%), 11 educational/career/experiences(5.1%), 9 self-concepts(4.2%), 4 welfare services(1.9%). Fourth, the current status of MZ generation research methods was quantitative research(survey/experiment) 125(58.4%), qualitative research(depth interview/participant observation) 42(19.6%), theory/literature research 35(16.4%) and mixed research 12(5.6%). Fifth, the study on the lifestyle of the MZ generation was conducted in four cases, one in 2016, one in 2019, two in 2020. This study is meaningful in that it grasped the overall flow of data of information exchange that can share the research trends of the MZ generation and suggested the basic data on the direction of future research, the individual tendency, behavior, and lifestyle characteristics of the MZ generation.
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