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Study on the trends in Korean clinical practice guidelines development

  • An, So-Youn;Kim, Hyun Jeong;Kim, Seungoh;Kim, Jongbin;Seo, Kwang-Suk;Lee, Deok-Won;Hwang, Kyung-Gyun
    • Journal of Dental Anesthesia and Pain Medicine
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    • v.16 no.1
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    • pp.31-37
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    • 2016
  • Background: The definition of evidence-based clinical practice guidelines (CPGs) is "statements that are systematically developed to assist in the doctors' and patients' decision-making in certain situations." This study aims to establish the concept of evidence-based CPGs and investigate the development status to seek measures to apply evidence-based methods to CPG development for dental sedation in Korea. Methods: The study conducted systematic searching methods based on evidence-based CPGs. Articles published between 1995 to 2015 were searched on a Korean database and the international database PubMed. The search was based on keywords related to four subjects (dentistry, clinical practice, guideline, recommendation). Two authors independently reviewed the searched articles to determine their analysis inclusion and the convergence stages, and to arrive at a conclusion through discussion. Results: A total of 65 Korean CPGs were included. There were 51 medical guidelines, of which seven were dental and seven were Oriental medicine. Conclusions: As a basic direction for the development of evidence-based CPGs, this work suggests the following: increased awareness; consensus on the need to supply evidence-based development methods; education, computerization, and systematic observation of evidence-based CPG development methods; continuous research development and distribution of CPGs; and creation of a database for Korean clinical dentistry practice outcomes

A Study on the Database Construction and the Management System Development of Water-Facility Using GSIS (GSIS를 이용한 상수도시설물의 데이터베이스 구축 및 관리시스템 개발에 관한 연구)

  • Kim, Young-Kon
    • Journal of Korean Society for Geospatial Information Science
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    • v.10 no.1 s.19
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    • pp.109-123
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    • 2002
  • The purpose of this study construct water-facility Database and to develop its management system using GSIS. We used route system and event table that are data model in GSIS for the construction of water valves on water facility pipe. A water-facility management system using GSIS was developed and was actually applied for the city of Yosu and compared with conventional water-facility management systems in terms of workability, information searching cost, and database management efficiency. The system has also been compared with those of two other local governments in terms of functions, process time, and conveniences. The generalization of the work model for water-facility system was also attempted based on the data collected from three local governments and it was revised by the work model of the wide area water-facility system. The generalized work model in this study was compared with other two local governments' work models. The generalized work model will enable local governments to develop more efficient and economical water-facility management system by GSIS in future.

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Identification of Hub Genes in the Pathogenesis of Ischemic Stroke Based on Bioinformatics Analysis

  • Yang, Xitong;Yan, Shanquan;Wang, Pengyu;Wang, Guangming
    • Journal of Korean Neurosurgical Society
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    • v.65 no.5
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    • pp.697-709
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    • 2022
  • Objective : The present study aimed to identify the function of ischemic stroke (IS) patients' peripheral blood and its role in IS, explore the pathogenesis, and provide direction for clinical research progress by comprehensive bioinformatics analysis. Methods : Two datasets, including GSE58294 and GSE22255, were downloaded from Gene Expression Omnibus database. GEO2R was utilized to obtain differentially expressed genes (DEGs). Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis of DEGs were performed using the database annotation, visualization and integrated discovery database. The protein-protein interaction (PPI) network of DEGs was constructed by search tool of searching interactive gene and visualized by Cytoscape software, and then the Hub gene was identified by degree analysis. The microRNA (miRNA) and miRNA target genes closely related to the onset of stroke were obtained through the miRNA gene regulatory network. Results : In total, 36 DEGs, containing 27 up-regulated and nine down-regulated DEGs, were identified. GO functional analysis showed that these DEGs were involved in regulation of apoptotic process, cytoplasm, protein binding and other biological processes. KEGG enrichment analysis showed that these DEGs mediated signaling pathways, including human T-cell lymphotropic virus (HTLV)-I infection and microRNAs in cancer. The results of PPI network and cytohubba showed that there was a relationship between DEGs, and five hub genes related to stroke were obtained : SOCS3, KRAS, PTGS2, EGR1, and DUSP1. Combined with the visualization of DEG-miRNAs, hsa-mir-16-5p, hsa-mir-181a-5p and hsa-mir-124-3p were predicted to be the key miRNAs in stroke, and three miRNAs were related to hub gene. Conclusion : Thirty-six DEGs, five Hub genes, and three miRNA were obtained from bioinformatics analysis of IS microarray data, which might provide potential targets for diagnosis and treatment of IS.

Optimization of Post-Processing for Subsequence Matching in Time-Series Databases (시계열 데이터베이스에서 서브시퀀스 매칭을 위한 후처리 과정의 최적화)

  • Kim, Sang-Uk
    • The KIPS Transactions:PartD
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    • v.9D no.4
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    • pp.555-560
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    • 2002
  • Subsequence matching, which consists of index searching and post-processing steps, is an operation that finds those subsequences whose changing patterns are similar to that of a given query sequence from a time-series database. This paper discusses optimization of post-processing for subsequence matching. The common problem occurred in post-processing of previous methods is to compare the candidate subsequence with the query sequence for discarding false alarms whenever each candidate subsequence appears during index searching. This makes a sequence containing candidate subsequences to be accessed multiple times from disk, and also have a candidate subsequence to be compared with the query sequence multiple times. These redundancies cause the performance of subsequence matching to degrade seriously. In this paper, we propose a new optimal method for resolving the problem. The proposed method stores ail the candidate subsequences returned by index searching into a binary search tree, and performs post-processing in a batch fashion after finishing the index searching. By this method, we are able to completely eliminate the redundancies mentioned above. For verifying the performance improvement effect of the proposed method, we perform extensive experiments using a real-life stock data set. The results reveal that the proposed method achieves 55 times to 156 times speedup over the previous methods.

A Study on Design of Annotation Database for Visible Human (인체영상 어노테이션 DB 설계에 관한 연구)

  • Ahn, bu-young;Lee, seung-bock;Han, Geon;Lee, sang-ho
    • Proceedings of the Korea Contents Association Conference
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    • 2008.05a
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    • pp.819-822
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    • 2008
  • As the IT and computer network technology is developed very rapidly, the quantity of digital contents is increased and disseminated more widely. The digital contents is generally expressed in 2 or 3 dimensional multimedia format and the visible human image that is taken from human body is very important because of its variety of usefulness. The KISTI(Korea Institute of Science and Technology Information) is now constructing various Korean human informations such as visible Korean, digital Korean, human bone property and human models. These informations are accessable through the internet. However, these human images are not easily understandable for general users because they are specialized in medical image field and there is no detailed explanation data. In this study, we designed the annotation database and searching interface for KISTI's visible Korean database. This annotation database involved the detailed explanation and special note of visible Korean data and it can connect the image and text data of visible Korean with each other. By studying this database and interface design, the KISTI's visible Korean database is more easily accessable and understandable to general users and it can promote the usage of visible Korean data more widely.

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UML Design of Graphic User Interface for Aerial Triangulation Using ArcGIS

  • 최선옥;김정우;염재홍
    • Proceedings of the Korean Society of Surveying, Geodesy, Photogrammetry, and Cartography Conference
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    • 2003.10a
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    • pp.225-230
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    • 2003
  • Efficient representation is crucial in the analysis of complex geospatial information. In case of aerial triangulation, most of currently available software are designed as black boxes where only an experienced user would be able to prepares the preformatted input file and interprete the result of the adjustment. This paper introduces a solution to this problem through the UML design of a Graphical User Interface (GUI) for the aerial triangulation task. The design was then implemented with ArcGIS. The error of the exterior orientation of each aerial Imagery was represented with a 3-D error ellipse, enabling the visualization of the adjustment result. The attributes of images and points (control points, tie points and image points) were maintained as a database which enables the searching and querying of adjustment information.

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Similarity Measurement of Part Specifications based on Ontology and ELECTRE IS (온톨로지와 ELECTRE IS을 활용한 사양 기반 부품 유사도 측정 방법)

  • Mun, Du-Hwan;Hwang, Ho-Jin
    • Korean Journal of Computational Design and Engineering
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    • v.15 no.2
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    • pp.144-156
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    • 2010
  • When existing parts are re-used for the development of a new product or business-to-business transactions, a method for searching parts from a part database that meets user's requirements is necessary. To this end, it is important to develop a part search method which is able to measure similarity between parts and user's input data with generality as well as robustness. In this paper, the authors suggest a method for measuring part similarity using ontology and multi-criteria decision making method and address its technical details. The proposed method ensures the interoperability with existing engineering information management systems, represents part specifications systematically, and has generality in the procedure for comparing part specifications. The case study for ejector pins having been conducted to demonstrate the proposed method is also discussed.

ICAIM;An Improved CAIM Algorithm for Knowledge Discovery

  • Yaowapanee, Piriya;Pinngern, Ouen
    • 제어로봇시스템학회:학술대회논문집
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    • 2004.08a
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    • pp.2029-2032
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    • 2004
  • The quantity of data were rapidly increased recently and caused the data overwhelming. This led to be difficult in searching the required data. The method of eliminating redundant data was needed. One of the efficient methods was Knowledge Discovery in Database (KDD). Generally data can be separate into 2 cases, continuous data and discrete data. This paper describes algorithm that transforms continuous attributes into discrete ones. We present an Improved Class Attribute Interdependence Maximization (ICAIM), which designed to work with supervised data, for discretized process. The algorithm does not require user to predefine the number of intervals. ICAIM improved CAIM by using significant test to determine which interval should be merged to one interval. Our goal is to generate a minimal number of discrete intervals and improve accuracy for classified class. We used iris plant dataset (IRIS) to test this algorithm compare with CAIM algorithm.

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Progressive Image Coding based on SPIHT Using Object Region Transmission Method by Priority (객체 영역 우선 전송 기법을 이용한 SPIHT기반 점진적 영상 부호화)

  • 최은정;안주원;강경원;권기룡;문광석
    • Proceedings of the IEEK Conference
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    • 2000.11d
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    • pp.53-56
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    • 2000
  • In progressive image coding, if object region that have main contents in image are transmitted prior to the remained region, this method will be very useful. In this paper, the progressive image coding based on SPIHT using object region transmission method by priority is proposed. First, an original image is transformed by wavelet. Median filtering is used about wavelet transformed coefficient region for extracting object region. This extracted object region encoded by SPIHT. Then encoded object region are transmitted in advance of the remained region. This method is good to a conventional progressive image coding about entire original image. Experimental results show that the proposed method can be very effectively used for image coding applications such as internet retrieval and database searching system.

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The Design and Implementation of Elementary School Library System Based on Web Database (웹 데이터베이스를 기반으로 한 초등학교 도서실 시스템 설계와 구현)

  • 손창익;설문규
    • Journal of the Korea Computer Industry Society
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    • v.2 no.4
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    • pp.491-506
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    • 2001
  • This system can perform efficient administration in a searching, lending and returning books. And also with this system, many styles of reading education is possible by considering properties of Elementary School. Using the system teachers and students can exchange a information about books or reading together. We organized the system to aid teachers in administration and assistance to students by joining the admittance of use, and to manage a library efficiently in consideration of understanding one another and several conditions in use of library. Besides, students can be appraised their reading process, so with the result that they will be a good reader.

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