• Title/Summary/Keyword: Data science

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Exploring the contextual factors of episodic memory: dissociating distinct social, behavioral, and intentional episodic encoding from spatio-temporal contexts based on medial temporal lobe-cortical networks (일화기억을 구성하는 맥락 요소에 대한 탐구: 시공간적 맥락과 구분되는 사회적, 행동적, 의도적 맥락의 내측두엽-대뇌피질 네트워크 특징을 중심으로)

  • Park, Jonghyun;Nah, Yoonjin;Yu, Sumin;Lee, Seung-Koo;Han, Sanghoon
    • Korean Journal of Cognitive Science
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    • v.33 no.2
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    • pp.109-133
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    • 2022
  • Episodic memory consists of a core event and the associated contexts. Although the role of the hippocampus and its neighboring regions in contextual representations during encoding has become increasingly evident, it remains unclear how these regions handle various context-specific information other than spatio-temporal contexts. Using high-resolution functional MRI, we explored the patterns of the medial temporal lobe (MTL) and cortical regions' involvement during the encoding of various types of contextual information (i.e., journalism principle 5W1H): "Who did it?," "Why did it happen?," "What happened?," "When did it happen?," "Where did it happen?," and "How did it happen?" Participants answered six different contextual questions while looking at simple experimental events consisting of two faces with one object on the screen. The MTL was divided to sub-regions by hierarchical clustering from resting-state data. General linear model analyses revealed a stronger activation of MTL sub-regions, the prefrontal lobe (PFC), and the inferior parietal lobule (IPL) during social (Who), behavioral (How), and intentional (Why) contextual processing when compared with spatio-temporal (Where/When) contextual processing. To further investigate the functional networks involved in contextual encoding dissociation, a multivariate pattern analysis was conducted with features selected as the task-based connectivity links between the hippocampal subfields and PFC/IPL. Each social, behavioral, and intentional contextual processing was individually and successfully classified from spatio-temporal contextual processing, respectively. Thus, specific contexts in episodic memory, namely social, behavior, and intention, involve distinct functional connectivity patterns that are distinct from those for spatio-temporal contextual memory.

The Gene Effect of Culm Length and Ear Length Using Isogenic Lines in Barley (동질유전자계통을 이용한 보리의 간장 및 수장유전자효과)

  • Cho, Chang-Hwan;Lee, Eun-Sup;Sung, Yeol-Kyu
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.33 no.3
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    • pp.270-280
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    • 1988
  • This experiment was conducted to evaluate the main effects and pleiotropic effects of two comparable isogenic lines for culm and spike length in hulled barley and observed various agronomic characteristics, yield and yield components under the conditions of heavy fertilizer application and high planting densities. Three isogenic lines, culm, spike and culm and spike, were planted and to obtain basic data for improving high-yielding and quality of hulled barley at Experiment Farm, Dankook Univ., Cheonan city in 1985. Differences of culm length between two comparable isogenic lines, short culmed line (SCL) and medium culmed line (MCL), in isogenic lines for culm length showed highly significant differences. And differences of spike length between two comparable isogenic lines, short spike line (SSL) and medium spike line (MSL), in isogenic lines for spike length showed highly significant differences. Differences of culm and spike length between two comparable isogenic lines, short culmed and spike line (SCSSL) and medium culmed and spike line (MCMSL), short culmed and spike line (SCSSL) and long culmed and spike line (LCLSL), in isogenic lines for culm and spike length showed highly significant differences. Characteristics affected highly by the genes of culm length in isogenic lines for culm length were heading days, the 1st and 2nd internode length, No. of grains per spike, No. of spikes/m$^2$, and one litre weight. Characteristics affected highly by the genes of spike length in isogenic lines for spike length were No. of spike nodes, heading days, maturity days, thousand grain weight and one litre weight. Characteristics affected highly by the genes of culm and spike length in isogenic lines for culm and spike length were No. of spike nodes, the 2nd, 3rd and 4th internode length, thousand grain weight and grain yield. Grain yield of SCL, MSL, MCMSL and SCSSL was more than grain yield of MCL, SSL, SCSSL and LCLSL, respectively. Maturity days of SCL, MSL, SCSSL and LSLSL were faster than maturity days of MCL, SSL, MCMSL and SCSSL, respectively.

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Effect of Soil Temperatures on Seedling Emergence in Direct Seeding on Dry Paddy (벼 건답직파에서 파종기 지온이 출아에 미치는 영향)

  • Soh, Chang-Ho;Yun, Jin-Il;Rho, Yeong-Deok;Kim, Moo-Sung;Kwon, Shin-Han
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.40 no.5
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    • pp.580-586
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    • 1995
  • Soil temperatures at depths of 1~5cm are important to the germination and emergence of dry seeded-rice. An automated weather station was used to monitor the hourly weather parameters at Experiment Farm, Kyung Hee University from April 21 to May 30 in 1994. The data was analyzed to figure out the 24-hour temporal changes in air 1.5m above ground and soil temperatures under ground of 0, 2.5, 5, 10 and 20cm. The fluctuations of soil temperature were greatest at the soil surface and decreased with increasing depth. Mean soil temperatures at depth of 2.5cm were about 3$^{\circ}C$ higher than mean air temperatures during the observation period. Although mean soil temperatures at depth of 2.5cm during 10 or 15 days after April 21, May 1 and May 11 showed almost same temperatures, the distribution patterns of temperature regime were different from each other. Rice cultivars, Hwasung, Seohae, Nampung, IR60 and CR155, were seeded at depth of 2.5cm on April 21, May 1 and May 11, respectively. The periods of seedling emergence(PSE) varied in accordance with cultivars and seeding dates. PSE was correlated with accumulated daily mean air temperatures and accumulated hours classified by temperature regimes.

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The Trend of Cigarette Design and Tobacco Flavor System Development

  • Wu, Jimmy Z.
    • Journal of the Korean Society of Tobacco Science
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    • v.24 no.1
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    • pp.67-73
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    • 2002
  • In light of addressing consumer health concern, coping with anti-tobacco movement, and promoting new product, tobacco industry is actively pursuing to make a new generation of cigarettes with low tar and nicotine deliveries, and less harmful substances. Low tar and low nicotine cigarettes increases their market shares dramatically world wide, especially in KT&G, multinational tobacco companies, EU countries, even in China regulated by CNTC to set up yearly target to lower tar and nicotine deliveries. On the other hand, to design a new cigarette with reduced harmful substances begins to gain speed. The "modified Hoffmann list" publishes thirty plus substances in tobacco leaf and main smoke stream, which is the prime suspect causing health problems. Various ways and means are developed to reduce such components including new tobacco breeds, new curing method, tobacco leaf treatment before processing, selected filtration system, innovated casing system to reduce free radicals, as well as some non conventional cigarette products. In TSRC held this year, the main topic is related to reduce tobacco specific nitrosamines in tobacco leaf. The new generation of cigarette is in the horizon. It still needs a lot help to produce commercial products with satisfied taste and aroma characters. The flavor industry is not regulated by many governments demanding which ingredients might or might not be for tobacco use. However, most of the cigarette companies self impose a list of ingredients to guide flavor suppliers to design flavors. Unfortunately, the number of ingredients in those lists is getting shorter every year. It is understandable that the health is not the only reason. Some cigarette companies are playing safe to protect the company from potential lawsuit, while others are just copying from their competitors. Moreover, it is obvious that it needs more assistance from casings and flavors to design new generation of cigarettes with missing certain flavor components in tobacco leaf and main smoke stream. These flavor components are either non-existed or at lower level at new form of cured tobacco leaf or filtered in the main smoke stream along with reduced harmful substances. The use of carbon filters and other selected filtration system poses another tough task for flavor system design. Specific flavor components are missing from the smoke analysis data, which brings a notion of "carbon taste" and "dryness" of mouth feel. It is ever more demanded by cigarette industry to flavor suppliers to produce flavors as body enhancer, tobacco notes, salivating agents, harshness reducer, and various of aromatic notes provided they are safe to use. Another trend is that water based flavor or flavor with reduced ethanol as solvent is gaining popularity. It is preferred by some cigarette companies that the flavor is compounded with all natural ingredients or all ingredients should he GMO free. The new generation of cigarettes demands many ways of new thinking process. It is also vital for tobacco industry. It reflects the real needs for the consumers that the cigarette product should be safe to use as well as bearing the taste and aroma characters smokers always enjoyed. An effective tobacco flavor system is definitely a part of the equation. The global trend of tobacco industry is like trends of any other industries lead by consumer needs, benefited with new technology availability, affected by the global economy, and subjected for various rules and regulations. Anti-tobacco organizations and media exceptionally scrutinize cigarette, as a legal commercial product. Cigarette is probably the most studied commercial product for its composition, structure, deliveries, effects, as well as its new developmental trend. Therefore, any new trend of cigarette development would be within these boundaries. This paper is trying to point out what it would be like for tobacco industry in the next few yews and what concerns the tobacco industry. It focuses mostly on the efforts to produce safer cigarettes. It is such a vital task for the tobacco industry and its affiliate industries such as cigarette papers, filters, flavors, and other materials. The facts and knowledge presented in this paper might be well known for the public. Some of the comments and predictions are very much personal opinion for a further discussion.

High-Risk Area for Human Infection with Avian Influenza Based on Novel Risk Assessment Matrix (위험 매트릭스(Risk Matrix)를 활용한 조류인플루엔자 인체감염증 위험지역 평가)

  • Sung-dae Park;Dae-sung Yoo
    • Korean Journal of Poultry Science
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    • v.50 no.1
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    • pp.41-50
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    • 2023
  • Over the last decade, avian influenza (AI) has been considered an emerging disease that would become the next pandemic, particularly in countries like South Korea, with continuous animal outbreaks. In this situation, risk assessment is highly needed to prevent and prepare for human infection with AI. Thus, we developed the risk assessment matrix for a high-risk area of human infection with AI in South Korea based on the notion that risk is the multiplication of hazards with vulnerability. This matrix consisted of highly pathogenic avian influenza (HPAI) in poultry farms and the number of poultry-associated production facilities assumed as hazards of avian influenza and vulnerability, respectively. The average number of HPAI in poultry farms at the 229-municipal level as the hazard axis of the matrix was predicted using a negative binomial regression with nationwide outbreaks data from 2003 to 2018. The two components of the matrix were classified into five groups using the K-means clustering algorithm and multiplied, consequently producing the area-specific risk level of human infection. As a result, Naju-si, Jeongeup-si, and Namwon-si were categorized as high-risk areas for human infection with AI. These findings would contribute to designing the policies for human infection to minimize socio-economic damages.

Association between dietary protein intake and overweight and obesity among Korean children and adolescents: data from the 2014-2019 Korea National Health and Nutrition Examination Survey (한국 아동 및 청소년의 단백질 섭취와 과체중 및 비만과의 연관성: 2014-2019년 국민건강영양조사 자료를 활용하여)

  • Sumin Kim;Kyungho Ha
    • Journal of Nutrition and Health
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    • v.56 no.1
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    • pp.54-69
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    • 2023
  • Purpose: Proteins are major components of the body and essential nutrients for proper growth and development. However, studies on protein intake in children and adolescents are insufficient. A few previous studies have reported the relationship with growth indicators, but results vary depending on the source of protein. Therefore, the current study investigates the relationship between protein intake and overweight and obesity among children and adolescents in Korea. Methods: Based on the 2014-2019 Korea National Health and Nutrition Examination Survey, 5,567 children and adolescents aged 6-18 years, who participated in a 24-hour dietary recall with information on height and weight, were included in this study. Protein intake was estimated as percentage of total energy (% of energy) and was classified into animal and plant protein according to the food source. Overweight and obesity were defined using the 2017 pediatric and adolescent growth chart. Results: Total protein intake of the subjects was estimated as 14.5% of total energy (animal protein 8.3% and plant protein 6.3%). The group with the highest total protein intake had a higher odds ratio (OR) of overweight/obesity than those with the least protein intake (OR, 1.36, 95% confidence interval (CI), 1.10-1.67, p for trend = 0.003). When classified by food source, the group with the highest animal protein intake had a significantly higher OR of overweight/obesity than subjects with the lowest intake (OR, 1.30, 95% CI, 1.05-1.61, p for trend = 0.016). However, plant protein was not significantly associated with overweight/obesity. Conclusions: These findings suggest that a high intake of animal protein in children and adolescents increases the risk of being overweight and obese. In order to develop normal growth and prevent obesity in the future, it is necessary to determine an appropriate protein intake level through nutrition education programs and prospective studies on balanced protein intake.

Effects of the Aroma Roll-on Inhalation Method on Stress, Pain, Depression and Blood Pressure in the Elderly in a Senior Citizen Clubs (아로마 롤온 흡입법이 경로당 이용 노인의 스트레스, 통증, 우울 및 혈압에 미치는 효과 )

  • Eun-Kyoung Han;Soo-Ah Jo;Ga-Eul Park;Ji-Eun Kim;Soo-Yeon Lee;Eun-Kyung Choi;Yeon-Ju Chae;Eun-Bin Oh;Jo-Hyeon Kim;Ha-Young Lee;Ji-Woo Yang;Yeong-Ju Jeong;Soo-Ah Park;Jin-Ah Kwon;Min-Jung Kim;Eun-Seo Choi;Ju-Eon Yang;Ga-Eun Jo;Ji-Woo Yang
    • Journal of the Korean Applied Science and Technology
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    • v.40 no.1
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    • pp.13-23
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    • 2023
  • This study is an experimental study on the single group pre-post test design for the effects of the aroma inhalation method with roll-on on stress, pain, depression and blood pressure of the elderly. 33 elderly people who met the selection criteria participated among the elderly using the senior citizen clubs located in S city, Gyeonggi-do. The data collection period was from November 14, 2022 to December 19, 2022. A questionnaire consisting of stress, pain, depression, and blood pressure was measured before and after the aroma roll-on inhalation intervention. The components of aroma essential oil included Marjoram, Geranium, Peppermint and Orange sweet that were diluted in Jojoba oil which was the carrier oil. The aroma inhalation method with roll-on was carried out 3 times day for 4 weeks. In the result of this study, the aroma inhalation method with roll-on were statistically significant differences in stress(t=2.63, p=.013), pain(t=2.46, p=.019), and systolic blood pressure(t=3.01, p=.005) of the participants. Therefore, aroma roll-on therapy is expected to be available as a useful nursing intervention method for reducing stress, relieving pain, and managing blood pressure in the elderly using the senior citizen clubs.

Metatranscriptome-Based Analysis of Viral Incidence in Jujube (Ziziphus jujuba) in Korea (메타전사체 분석을 이용한 국내 대추나무의 바이러스 감염실태)

  • Hong-Kyu Lee;Seongju Han;Sangmin Bak;Minseok Kim;Jean Geung Min;Hak ju Kim;Dong Hyun Kang;Minhui Kim;Wonyoung Jeong;Seungbin Baek;Minjoo Yang;Taegun Lim;Chanhoon An;Tae-Dong Kim;Chung Youl Park;Jae Sun Moon;Su-Heon Lee
    • Research in Plant Disease
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    • v.29 no.3
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    • pp.276-285
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    • 2023
  • This work investigated the viral infection in jujube plants in Korea. A total of 61 samples with the symptoms of putative viral infection were collected from experimental fields and orchards. Thereafter, the samples were subjected to metatranscriptome analysis, Reverse transcription polymerase chain reaction analysis, and nucleotide sequence analysis. These analyses identified the presence of two DNA viruses, jujube-associated badnavirus (JuBV), jujube mosaic-associated virus (JuMaV), and one RNA virus, jujube yellow mottle-associated virus (JYMaV). All samples collected were confirmed to be infected by at least one of the three viruses, with most showed multiple infections. The detection rates of JuBV, JYMaV, and JuMaV were 100%, 90.2%, and 8.2%, respectively. Only three combinations of viral infections were found: 9.8% of samples showed single infection of JuBV, 82.0% showed double infection of JuBV+JYMaV, and 8.2% showed triple infection of JuBV+JYMaV+JuMaV. Sequence analysis of the three viruses showed very high homology with respective virus isolates reported in China. This study is predicted to provide fundamental data to produce virus-free jujube seedlings and represents the first report of JuBV and JuMaV infection in Korea.

Cone Characteristics and Seed Quality among Harvest Times in the Clonal Seed Orchard of Larix kaempferi (낙엽송 클론 채종원에서 구과 채취시기에 따른 구과특성 및 종자품질)

  • Ye-Ji Kim;Da-Eun Gu;Gyehong Cho;Heeyoon Choi;Yeongkon Woo;Chae-Bin Lee;Sungryul Ryu;Hye-Joon Joo;Kyu-Suk Kang
    • Journal of Korean Society of Forest Science
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    • v.112 no.3
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    • pp.352-362
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    • 2023
  • Harvest time is one of the most important determining factors of seed quality, especially for species that produce seeds over irregular and long-term periods, such as Larix kaempferi. A cone collection plan must be established to increase seed production efficiency and stable mass production. We investigated seed qualities such as seed efficiency, germination rate, and T50 (germination speed), with 7 or 8 cone collection times at a clonal seed orchard of L. kaempferi in Chungju between 2021 and 2022. A multivariate analysis was then performed for the collected data. In early August, decreases in the moisture contents and browning of cones were observed. These were followed by a decrease in germination rate, with a peak at the end of September, but no clear trend was observed. The later the cones were harvested, the better the seed vigor (T50). However, the seed yield and efficiency decreased owing to increases in seed scattering and the number of insect-damaged seeds. As a result, the optimal time of seed harvest for the seed orchard was in early August. To produce uniform seedlings, insect damage must be reduced through timely control and harvest cones in early September. This shows that the degree of browning and moisture content of cones can be used as indicators of the timing of cone collection in L. kaempferi seed orchards.

The Protective Role of Gleditsiae fructus against Streptococcus pneumoniae (폐렴 구균에 대한 조협의 보호 역할 연구)

  • Jun-ki Lee;Se-Hui Lee;Dong Ju Seo;Kang-Hee Lee;Sojung Park;Sun Park;Taekyung Kim;Jin-Young Yang
    • Journal of Life Science
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    • v.33 no.2
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    • pp.158-168
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    • 2023
  • Natural products have been used to mitigate the effects of cancer and infectious diseases, as they feature diverse bioactivities, such as antioxidant, antibacterial, anti-inflammatory, and immunomodulatory effects. Here, we chose 10 natural products that are well-known as pulmonary enhancers and investigated their bactericidal effects on Streptococcus pneumoniae. In the disk diffusion assay, the growth of S. pneumoniae was significantly regulated by G. fructus treatment regardless of extraction method used. We first adopted spraying as a novel delivery method for G. fructus. Interestingly, mice exposed to G. fructus three times a day for 2 weeks were resistant to S. pneumoniae intranasal infection (shown both through body weight loss and survival rates compared to the control group). Moreover, we confirmed that exposure to G. fructus regulated the colonization of the bacteria despite the sustained inflammation in the lung after exposure to S. pneumoniae, indicating that migrated inflammatory immune cells may involve a host defense mechanism against pulmonary infectious diseases. While a similar number of granulocytes (CD11b+Ly6C+Ly6G+), neutrophils (CD11b+Ly6CintLy6G+), and monocytes (CD11b+Ly6CintLy6G-) were found between groups, a significantly increased number of alveolar macrophages (CD11b+CD11chiF4/80+) was detected in BAL fluids of mice pre-exposed to G. fructus at 5 days after S. pneumonia infection. Taken together, our data suggest that this usage of G. fructus can induce protective immunity against bacterial infection, indicating that facial spray may be helpful in enhancing the defense mechanism against pulmonary inflammation and in evaluating the efficacy of natural products as immune enhancers against respiratory diseases.