• 농촌의학ㆍ지역보건
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• 제23권2호
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• pp.287-293
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• 1998

혈청 GGT는 임상적으로 널리 이용되고 있음에도 불구하고 정상 인구 집단에서의 행태적 관련 인자에 대해서는 잘 알려져 있지 않다. 본 연구에서는 경상남도 내의 농촌 지역인 울산시 울주군 두동면에서 1997년에 실시한 주민 건강 검진에 참여하였던 40세 이상의 남성 248명을 대상으로 혈청 GGT 활성도와 관련된 행태적 요인을 조사하였으며 다중 회귀 분석과 공분산 분석을 이용하여 혼란 변수의 영향을 통제하였다. 신체 비만지수(kg/$m^2$)와 알코올 섭취량(ml/day)이 증가함에 따른 혈청 GGT 활성도의 차이는 연령과 요인 상호간의 영향을 보정하였을 때 통계학적으로 유의하였다(p=0.051 및 p<0.001). 비음주자에서 신체 비만지수가 25 이상인 경우는 25 미만인 경우에 비해 혈청 GGT의 활성도가 통계학적요로 유의하게 상승하였으나(p=0.007), 음주자에서는 유의한 차이를 볼 수 없었다(p=0.892). 알코올 섭취는 신체 비만지수가 25미만인 경우와 25 이상인 경우 모두에서 혈청 GGT의 활성도 상승과 유의한 연관성을 보였다(p<0.001 및 p=0.002). 이상과 같은 소견은 농촌 지역 남성들에서 혈청 GGT의 활성도와 가장 밀접하게 관련된 요인이 음주, 그리고 비음주자에서의 비만임을 암시한다.

• 디지털융복합연구
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• 제16권10호
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• pp.313-321
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• 2018

본 연구는 조현병 입원환자를 대상으로 대사증후군 위험성 정도를 파악하고 관련요인을 파악하기 위한 서술적 상관 관계연구이다. 연구대상자는 G 광역시에 위치한 G 정신병원 조현병 입원환자 127명이다. 수집된 자료는 SPSS 22.0을 이용하여 기술통계, ${\chi}^2-test$, t-test, 로지스틱회귀분석을 실시하였다. 본 연구결과 대사증후군 유병율은 46.5%로 높게 나타났다. 대상자의 대사증후군은 신체질환 유무(${\chi}^2=11.51$, p<.001), 체질량 지수(${\chi}^2=13.59$, p<.001), 비만 인식(${\chi}^2=8.38$, p<.001), 올란자핀 복용(${\chi}^2=6.31$, p<.05)에서 통계적으로 유의한 차이가 있었다. 회귀분석 결과, 대사증후군 발생 위험도는 신체질환이 있는 경우 3.65배(95% CI=1.68~7.92), 체질량지수가 23이상인 경우 3.76배(95% CI=1.39~10.14), 올란자핀을 복용하는 경우 3.05배(95% CI=1.02~9.10) 더 증가하는 것으로 나타났다. 이 모형의 설명력은 총 29.1%로 나타났다. 따라서 본 연구에서 확인된 조현병 입원환자의 대사증후군 관련요인을 토대로 체계적인 대사증후군 관리와 예방을 위한 간호중재의 개발 및 제공이 요구된다.

• 대한지역사회영양학회지
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• 제11권5호
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• pp.575-586
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• 2006

This study was performed to compare nutrient intakes, diet quality and serum indices (TG, Total cholesterol, LDL-cholesterol, HDL-cholesterol, RBC, Hb, Hct, Serum iron, ferritin, MCV) of obese and normal weight children. The subjects were 149 children living in the Seoul and Gyeonggi areas. Each subject was assigned to one of such as normal weight group ($15th{\le}BMI$ percentile < 85th, n = 82) or obese children ($85th{\le}BMI$ percentile, n = 67) according to their percentile of BMI by The Korean Pediatric Society. Data on dietary intakes, body composition and serum indices were obtained. Differences of all the above variables were assessed. Energy, carbohydrate, fat, cholesterol, total fatty acid, SFA, MUFA, PUFA, phosphate, potassium, zinc, vitamin $B_1$ and vitamin $B_6$ intakes of girls in the obese group were higher than those of the normal weight group (p<0.05). The intake of fiber was as insufficient as below 50% of KDRIs in both groups. Nutrient adequacy ratio of calcium, iron, phosphate, zinc and folate in obese boys were lower than those of normal weight boys (p<0.05). Energy intakes of grain and milk and dairy food in the obese girl group ($905.9{\pm}344.5kcal,\;210.9{\pm}166.4kcal$) were higher than those of normal weight girls ($671.2{\pm}360.7kcal,\;184.0{\pm}103.5kcal$) (p<0.05). HDL-cholesterol level of obese boys ($52.7{\pm}6.3mg/dL$) was significantly lower than that of normal weight boys ($65.3{\pm}15.6mg/dL$). Serum iron level of obese boys and girls (boys: $79.4{\pm}32.6mg/dL$, girls: $98.3{\pm}16.2mg/dL$) was significantly lower than those of normal weight children (boys: $104.8{\pm}38.6mg/dL$, girls: $106.7{\pm}28.9mg/dL$) (p<0.05). These results suggest that there should be sensible food selection and more intakes of fruit and vegetable are needed to improve the nutritional status in obese children.

• 한국정보통신학회:학술대회논문집
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• 한국정보통신학회 2015년도 추계학술대회
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• pp.143-146
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• 2015

메타분석은 여러 실증연구의 정량적인 결과를 통합과 분석을 통해 전체 결과를 조망할 수 있는 기회를 제공하는 통계적 통합 방법이다. 우리나라 학술지에 게재된 대사증후군과 비만 위험요인에 관한 연구들을 계량적으로 통합하고 검토해보기 위해 진행하였다. 본 연구는 대사증후군과 비만에 대한 문헌적 고찰을 통해 선행연구를 살펴보고 열거된 요인에 관한 실증 분석된 연구들을 메타분석하기 위해 2000년-2015년 국내 학술지에 게재된 논문을 연구대상으로 하였다. 국내 학술지에 게재된 논문만 여과하여 조건에 부합한 총 36편의 논문을 연구에 대상으로 선정하였다. 메타분석 결과 허리둘레(복부비만) 사전사후 경로에서 가장 큰 효과크기(r = .420)인 것으로 나타났다. 두 번째 큰 효과 크기는 고밀도지단백콜레스테롤 사전사후 경로(r = -.402)인 것으로 나타났다. 그런데, 이완기혈압 사전사후 경로가 가장 작은 효과크기(r = .234)인 값을 확인할 수 있었다. 따라서 이러한 연구결과를 바탕으로 학문적 실무적 의의를 논의하고자 한다.

• 동아시아식생활학회지
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• 제17권3호
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• pp.338-350
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• 2007

The objectives of this study were to analyze nutrition-related problems and to develop the nutrition education programs for high school students A survey was conducted with 500 students in the second grade level at high schools in Daegu who differed in socio-economic characteristics. In addition, body composition analysis was accomplished by the Inbody 3.0. The developed questionnaires were distributed and 481 questionnaires were collected with a 96.2% of response rate. Statistical data analysis was completed using SPSS WIN(ver.12.0) for descriptive analysis, reliability analysis, factor analysis, t-tests and $X^2$-tests. We first analyzed students' problems related to nutrition and environmental factors. In a question addressing skipping breakfast, only 11.5% answered they "do not eat" breakfast. In regards to BMI, the male students' degree of obesity was higher. Second, we analyzed living environments, which greatly influence dietary behavior. For the snacks-related categories, most of the students liked bread, cake and other snacks. When they chose the snacks, they mainly considered taste. There were significant difference among the males and females(p<.01) in terms of snacks intake habits, where 43.1 % of the males answered they snack "occasionally" and 43.4% of the females answered they snack "according to how they feel". In the case of beverages, the males consumed significantly more(p<.001). Based on their regional groups, the area A group preferred milk and milk products, and the area B group preferred soft drinks. As for the time of beverage intake, 77.6% of the females answered "with snacks", which was significantly higher than 61.4% of the males(p<.001), 12.2% of the males drank beverages after exercise. For late snacking, 68.0% of the male students and 71.1 % of the female students consumed late snacks. Most of them preferred bread, cake and other snacks. The reasons for taking a late snack were "when I feel hungry" by 61.8% of the males which was higher than the females(p<.001), 23.6% of the females consumed late snacks "impulsively". Ideally, in order to improve the food habits of high school students effective and practical nutrition education programs that consider gender and regional school group, should be carried out.

• Molecules and Cells
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• 제38권12호
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• pp.1037-1043
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• 2015

The TAZ activator 2-butyl-5-methyl-6-(pyridine-3-yl)-3-[2'-(1H-tetrazole-5-yl)-biphenyl-4-ylmethyl]-3H-imidazo[4,5-b]pyridine] (TM-25659) inhibits adipocyte differentiation by interacting with peroxisome proliferator-activated receptor gamma. 1 TM-25659 was previously shown to decrease weight gain in a high fat (HF) diet-induced obesity (DIO) mouse model. However, the fundamental mechanisms underlying the effects of TM-25659 remain unknown. Therefore, we investigated the effects of TM-25659 on skeletal muscle functions in C2 myotubes and C57BL/6J mice. We studied the molecular mechanisms underlying the contribution of TM-25659 to palmitate (PA)-induced insulin resistance in C2 myotubes. TM-25659 improved PA-induced insulin resistance and inflammation in C2 myotubes. In addition, TM-25659 increased FGF21 mRNA expression, protein levels, and FGF21 secretion in C2 myotubes via activation of GCN2 pathways (GCN2-$phosphoelF2{\alpha}$-ATF4 and FGF21). This beneficial effect of TM-25659 was diminished by FGF21 siRNA. C57BL/6J mice were fed a HF diet for 30 weeks. The HF-diet group was randomly divided into two groups for the next 14 days: the HF-diet and HF-diet + TM-25659 groups. The HF diet + TM-25659-treated mice showed improvements in their fasting blood glucose levels, insulin sensitivity, insulin-stimulated Akt phosphorylation, and inflammation, but neither body weight nor food intake was affected. The HF diet + TM-25659-treated mice also exhibited increased expression of both FGF21 mRNA and protein. These data indicate that TM-25659 may be beneficial for treating insulin resistance by inducing FGF21 in models of PA-induced insulin resistance and HF diet-induced insulin resistance.

• 지역사회간호학회지
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• 제14권3호
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• pp.507-519
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• 2003

Purpose: The purpose of this study was to identify the prevalence, health behaviors, and control of hypertension in rural areas in Korea. Method: A total of 927 subjects above age 20 were selected from the areas which fell under the jurisdiction of the 24 Community Health Center located in Chungcheongbuk-do. The employees in the Community Health Center visited and interviewed patients. Data were collected using a questionnaire from July to October 2002. Result: The result showed that women had higher hypertension prevalence rates than men and the increment of its rate leveled up according to age. The hypertension prevalence rate was significantly high when the monthly income was less than 1 million won, their type of the Medical Insurance was the Guardian, they were only able to read Korean characters, and they were bereaved of spouses. In the Health behavior related to hypertension, the hypertension group showed a significantly lower level than the non- hypertension group in terms of drinking rate, smoking rate, intake of salt and intake of meat. There was no significant difference in the exercise rate and coffee intake rate between these groups. In the degree of the obesity the hypertension group was significantly higher than the non-hypertension group. The factors related to hypertension were that the duration for the incidence of hypertension was 12 to 60 months and took up 41.2%. The places where the medical check-ups occurred were the Community Health Center at 46.6%, the medical institution was mostly hospitals recording 46.5%. There were 66.1% of the targets who knew well about their blood pressure and there were 64.7% people who received education about it. As for the education place, the rate of Community Health Center was mostly high and it stood at 77.0%. In the aspect of the management of hypertension, the targets who took medicine on a regular basis were up to 76.1% and the targets who measured blood pressure once a month happened to be about 46.1 %. The targets who always recorded their blood pressure were 3.8%, chest X-ray as a related examination of hypertension reached 32.6%, electrocardiogram examination was 36.2%, cholesterol and serum lipid examination took up 33.6%, and the eye ground examination took 7.3%, which showed the lowest level of all.

• 대한예방한의학회지
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• 제8권1호
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• pp.19-32
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• 2004

This study was conducted to evaluated musculoskeletal subjective symptoms and the degree of stress of industrial workers to present fundamental materials of preventive oriental medicine for improving their health and quality of life. During the medical examination with oriental medicine method, presence of subjective symptoms of musculoskeletal pain, Psychosocial Well-being Index(PWI) and life style were checked by using questionnaire method in 474 industrial workers. The collected data were analyzed with crosstabs, ANOVA and T-test. The results were as follows; 1. In general differences according to musculoskeletal subjective symptoms, education level of high school graduation had significantly higher distribution than that of below middle school or above university graduation in the pain present group. 2. In the musculoskeletal subjective symptoms and the degree of stress, all of Factor1, Factor2. Factor3, Factor4. and PWI had higher score in pain present group than in pain free group and the difference was statistically significant. 3. According to degree of stress and general character of subjects, single and education level of high school graduation had high score in Factor2, Factor3 and PWI. Factor1 and Factor3 was high in income group of low 1.49 million won. Factor2, Factor4, and PWI was high significantly in income group of 1.50 - 2.99 million won. In job type, manufacturing worker group had significantly high score in Factor3. 4. In degree of stress and life style difference, there was significant difference in PWI score in the field of alcohol chinking, smoking, exercise, obesity except sleeping hours. In the present study. as a result, it is found out that musculoskeletal subjective symptoms present group had higher score in psychosocial stress across the fields than symptom-free group and it is recommended that continuous studies on the relationship of job-related musculoskeletal disorders and psychosocial stress should be performed for improvement and prevention of mental and physical health of industrial worke

• 한국산학기술학회논문지
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• 제17권1호
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• pp.62-71
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• 2016

식품 불안정성(Food insecurity)은 불건강과 연관성이 있다. 특히 식품 불안정성은 우울증, 우울감 등 정신건강의 문제를 야기한다고 알려져 왔다. 본 연구는 대한민국 성인의 식품 불안정성 상태를 파악하고 식품 안정성 구분에 따른 정신건강과의 연관성에 대해 알아보는 것이 그 목적이다. 연구 대상자는 2013년 국민건강영양조사에 참여한 성인 5,685명을 대상으로 하였다. 결과변수로 우울감과 우울증을 선정하였으며 우울감은 최근 1년 내 2주 이상 우울감이 있는 경우로 정의하였고 우울증은 평생 우울증 진단 여부로 정의하였다. 빈도, 평균 값을 산출하였고, 다변량 로지스틱회귀분석을 사용하여 식품불안정성과 우울감, 우울증의 관련성을 파악하였다. 연구 결과 식품 불안정성은 고 연령, 사회경제적 수준이 낮은 집단에서 유의하게 높은 빈도를 보였다. 전체 대상자의 3.8%가 우울증, 11.3%가 우울감을 호소하였다. 식품 불안정성은 비 보정모델, 성-연령 보정 모델에서 우울감, 우울증을 유의하게 증가하였다. 혼란변수를 보정한 최종 모델에서 식품 불안정성 그룹은 식품 안정성을 확보한 그룹에 비하여 우울증이 3.49배, 우울감이 3.7배 증가하였다. 식품 불안정성 초기 그룹은 최종 모델에서 우울감에서만 1.69배 증가 결과를 보였다. 연구 결과 한국 성인의 식품 불안정성과 우울감, 우울증의 유의한 증가를 확인할 수 있었다. 향후 식품불안정성을 감소시키고 이로 인한 불건강을 해소하기 위하여 중재프로그램을 실시할 때 영양, 건강프로그램의 단순 접근이 아니라 영양, 건강증진팀 및 식품의 안정적 수급을 위한 정책적 지원까지 다학제적 접근이 반드시 필요하다.

• 한국치위생학회지
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• 제4권1호
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• pp.31-48
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• 2004

Dental caries taking place with milk teeth affects eruption of permanent teeth adversely, and thus, it is very important to prevent dental caries from taking place with a child in maintaining his/her physical, mental and emotional health. In this study as conducted to obtain basic data to be required for development of a program for letting preschool children form a habitual life for oral health and right dietary life, a total 172 children aged 5 years and 6 years were selected from children who lived in Hwasung-si, Kyunggi-do and attended preschools (childrens houses) located there with the consent of their guardians. Then, the weight length index (WLI) and blood components of each child were analyzed, and each relation between the weight length index (WLI) and dental caries of milk teeth and between blood components and dental caries of milk teeth was comparatively examined, and thereby, the following results were obtained. When the dmf rate of each group according to the obesity was examined, it was found to be 87.50% in the under-weight group, 71.20% in the normal weight group and 83.87% in the overweight group. And when the dmft rate of each group was examined, it was found to be 48.43% in the under-weight group, 37.10% in the normal weight group and 47.17% in the overweight group. Also, when the dmft index of each group was examined, it was found to be 3.9 in the under-weight group, 3.0 in the normal weight group and 3.8 in the overweight group. That is to say, the under-weight group and the overweight group having an abnormal weight were found to be higher in all of the dmf rate, the dmft rate and the dmft index than the normal weight group. It could be, therefore, known that normal weight should be maintained in order to prevent dental caries of milk teeth. And, it is thought that a right dietary life habit ensuring intake of balanced nutrients should be formed for maintenance of a normal weight. As a result of examining the relation between nutrient components in blood and dental caries of milk teeth, in the case of children with no dental caries, inorganic nutrient components of blood had a tendency to be a little higher, but no statistical significance was observed therein. Meanwhile, it was found that there was a relation between blood type and the dmft index.