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Inhibitory Effect on TNF-${\alpha}$-Induced IL-8 Production in the HT29 Cell of Constituents from the Leaf and Stem of Weigela subsessilis

  • Thuong Phuong Thien;Jin WenYi;Lee JongPill;Seong RackSeon;Lee Young-Mi;Seong YeonHee;Song KyungSik;Bae KiHwan
    • Archives of Pharmacal Research
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    • v.28 no.10
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    • pp.1135-1141
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    • 2005
  • Twelve compounds were isolated from the MeOH extract of the leaf and stem of the Korean endemic plant Weigela subsessilis L. H. Bailey. Their chemical structures were elucidated on the basis of physicochemical and spectroscopic data and by comparison with those of published literatures. These compounds were identified as three sterols, ${\beta}$-sitosterol acetate (2), ${\beta}$-sitosterol (3), daucosterol (11), eight triterpenoids, squalene (1), ursolic acid (4), ilekudinol A (5), corosolic acid (6), ilekudinol B (7), esculentic acid (8), pomolic acid (9), asiatic acid (10), and one iridoid glycoside, alboside I (12). This is the first report pertaining to the isolation of these compounds from Weigela subsessilis L. H. Bailey. In addition, three compounds 7, 9, and 12 were found to display a strong inhibitory effect on the production of IL-8 in the HT29 cells stimulated by TNF-${\alpha}$.

Development of Attachable HOB Monitoring System with Performance Analysis (부착형 침상머리 각도 모니터링 시스템 개발 및 성능 분석)

  • Gyeong, G.Y.;Park, Y.S.;Lee, Y.S.
    • Journal of rehabilitation welfare engineering & assistive technology
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    • v.8 no.3
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    • pp.197-203
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    • 2014
  • In this paper, we develop an attachable head of bed(HOB) monitoring system, which can prevent ventilator associated pneumonia(VAP), and analyze the performance of the developed HOB monitoring system. The main purpose of the HOB monitoring system is to support visible HOB display for keeping patients' position effectively and collect data for analysis of the relation between HOB elevation and patients' symptom. The HOB monitoring system is developed in attached-type and uses an FIR filter with heuristic logic to remove the unwanted noise. The optical encoder is used for the performance analysis of the developed HOB monitoring system.

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Brand Awareness, Attributes and Purchase Behaviors for Luxury Products in the Age of McLuxury (명품 대중화 시대의 명품 브랜드 인지도와 주요 속성에 대한 인식 및 구매 행동)

  • Kim, Mi-Sook;An, Soo-Kyung
    • The Research Journal of the Costume Culture
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    • v.18 no.1
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    • pp.133-149
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    • 2010
  • The purpose of this study was to investigate the brand awareness, attributes and purchase behaviors for luxury products in the age of mcluxury. In-depth interviews were conducted to 18 consumers(10 singles, 8 married) in the age range of 20~49 and having purchased luxury products twice in last 1 year. The interviews were directed by a trained mediator according to the interview guidelines and recorded. Interviewees were asked to talk freely and protocols were made for data analysis. Similarities were found regarding the salient attributes, brand awareness of luxury products as known in general; however, the perceived importance of each attribute of luxury products seemed to be changed as mcLuxury has continued. Moreover, the consumers' attitudes toward the luxury products consumption tended to become favorable than before, and the motives to buy luxury products were more value-oriented and self fulfillment rather than display one's wealth. The buying behaviors of luxury products vary among different age groups. However, most of them tended to purchase luxury products at duty-free shops and premium outlets while traveling abroad, or bought them on sale at domestic department stores.

A study of the relationship between the subjective symptoms of VDT syndrome and occupational factors in VDT operators (VDT작업자의 작업조건과 다발하는 자각증상과의 관련성에 관한 연구)

  • Kim Kap-Sung;Lee Seung-Deok
    • Journal of Acupuncture Research
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    • v.18 no.6
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    • pp.70-83
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    • 2001
  • Objective : In order to investigate symptoms prevalence related to visual display terminal(VDT) syndrome, and to evaluate the variables affecting the development of the VDT syndrome. Methods : a questionnaire survey was conducted on 127(81 men and 46 women) VDT operators who had been studied in Soongsil University graduated school in Seoul. Result : As a result of analysis with data collected by questionnaire, l. Variables affecting the level of general symptoms were sex, the total time of VDT operation per day, type of typewriting, location of keyboard, illumination, VDT working duration, the time of VDT operation without rest. 2. Variables affecting the level of eye symptoms were sex, the total time of VDT operation per day, type of typewriting, VDT working duration, illumination, method of eye-resting. 3. Variables affecting the level of musculoskeletal symptoms were sex, the total time of VDT operation per day, the time of VDT operation without rest, illumination. Conculsions : In order to protect workers from VDT syndrome, it is urgently required to implement standard management recommendations including restriction of VDT working hours and allowance of more sufficient resting time for VDT workers.

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Comparison of Two Methods for Size-interpolation on CRT Display : Analog Stimulus-Digital Response Vs. Digital Stimulus-Analog Response (CRT 표시장치에서 두 형태의 크기-내삽 추정 방법의 비교 연구 : 상사자극-계수 반응과 계수 자극-상사반응)

  • Ro, Jae-ho
    • Journal of Industrial Technology
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    • v.14
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    • pp.127-140
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    • 1994
  • This study is concerned with the accuracy and the patterns when different methods was used in interpolation task. Although 3 methods employed the same modality for input (visual) and for output (manual responding), they differed in central processing, which method 1 is relatively more tendency of verbal processing, method 2 is realtively more tendency of spatial processing and method 3 needed a number of switching code (verbal/spatial) performing task. Split-plot design was adopted, which whole plot consisted of methods (3), orientations (horizon, vertical), base-line sizes (300, 500, 700 pixels) and split plot consisted of target locations (1-99). The results showed the anchor effect and the range effect. Method 2, method 3 and method 1 that order was better accuracy. ANOVA showed that the accuracy was significantly influenced by the method, the location of target, and its interactions ($method{\times}location$, $size{\times}location$). Analysis of error data, response time and frequency of under, just, over estimate indicated that a systematic error pattern was made in task and methods changed not only the performance but also the pattern. The results provided support for the importance of the multiple resources theory in accounting for S-C-R compatibility and task performance. They are discussed in terms of multiple resources theory and guidelines for system design is suggested by the S-C-R compatibility.

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Variables Affecting Brand Relationship Quality of Fashion Product Consumers (패션상품 소비자들의 상표관계본질에 영향을 미치는 변인 연구)

  • Chae, Jin-Mie
    • Journal of the Korean Home Economics Association
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    • v.46 no.8
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    • pp.121-133
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    • 2008
  • The purpose of this study was to decipher the BRQ (Brand Relationship Quality) Construct of fashion product consumers and to identify influencing variables. Consumption values of consumers, fashion product attributes and marketing communication instruments were investigated as affecting variables. A questionnaire was distributed to 350 women between the age of 20 and 50 living in Seoul and other metropolitan areas from Mar. 5 to Mar. 18, 2008. Collected data were analyzed by factor analysis, reliability, multiple regression, frequency and percentage using SPSS (Version 15,0) statistical Package. The results were as follows: Firstly, the BRQ Construct of fashion product consumers was proved to be composed of five factors; 'self-connective love', 'pursuing symbol', 'trust', 'intimacy', and 'knowledge'. Secondly, consumption values had a significant effect on the BRQ Construct and their explanatory power was 32%, 'Epistemic value' was the most significant variable affecting BRQ. 'Functional value' had a significant influence on some BRQ factors. Thirdly, explanatory power of fashion product attributes affecting BRQ was 45%. 'Aesthetic attribute' had significant effect on all BRQ factors, while 'functional attribute' showed significant effect on only 'pursuing symbol', 'trust', and 'intimacy'. Finally, marketing communication mixes showed 21% explanatory power and 'word of mouth' and 'display' among marketing communication mixes were found as the most influential variables affecting the BRQ Construct.

A Study on Repeated Processing using the Modified Median Filter in a High-Density Salt and Pepper Noise Environments (고밀도 Salt and Pepper 잡음 환경에서 반복처리를 이용한 변형된 메디안 필터에 관한 연구)

  • Hong, Sang-Woo;Gwon, Se-Ik;Kim, Nam-Ho
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2015.10a
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    • pp.312-314
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    • 2015
  • With progress in information technology, demand for imaging devices such as display devices is increasing. But noise occurs due to various reasons during the process of acquiring, transmitting or processing the image data. Filters used to remove salt and pepper noise include SMF, CWMF and AWMF. In areas where the noise density is high, the removal of noise is undermined. This paper suggests an adjusted median filter algorithm that transforms the noise pixels to more effectively remove salt and pepper noise.

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The Analysis of the Correlation between the Sustain-Electrode Gap of an AC-PDP and Address Discharge Characteristics (AC-PDP의 유지방전 전극사이의 간격과 어드레스 방전 특성과의 상관성 분석)

  • Lee, Young-Jun;Choi, Su-Sam;Park, Se-Kwang;Kim, Yong-Duk
    • The Transactions of the Korean Institute of Electrical Engineers C
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    • v.55 no.5
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    • pp.239-244
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    • 2006
  • To drive the high-image quality plasma displays of XGA and/or full-HD, we must effectively improve the driving waveform, which get the reset period for the stabilized control of wall charges, the address period to select discharge or non-discharge, and sustain period for luminance in 1 TV-frame, and also the display quality. To accomplish them, the development of the technology for the fast address discharge is required. In this paper, the correlation between the sustain-electrode gap and address discharge characteristics for the high-speed addressing was analyzed using the measurements of dynamic voltage margins. Results showed that the narrower the gap between the sustain electrodes, the narrower the with of the scan pulse became and a dynamic margin of data voltage of 29.2 V was obtained at scan pulse width of $1.0{\mu}s\;and\;V_{ramp}$ of 240 V for driving 4-inch test penal, which the gap between sustain electrodes was $65{\mu}m$.

Structural properties of carbon nanotubes: The effect of substrate-biasing (기판 바이어스에 따른 탄소 나노튜브의 구조적 물성)

  • Park, Chang-Kyun;Yun, Sung-Jun;Park, Jin-Seok
    • Proceedings of the KIEE Conference
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    • 2006.10a
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    • pp.36-37
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    • 2006
  • Both negative and positive substrate bias effects on the structural properties and field-emission characteristics are investigated. carbon nanotubes (CNTs) are grown on Ni catalysts employing an inductively-coupled plasma chemical vapor deposition (ICP-CVD) method. Characterization using various techniques, such as field-emission scanning electron microscopy (FESEM), high-resolution transmission electron microscopy (HRTEM), Auger spectroscopy (AES), and Raman spectroscopy, shows that the physical dimension as well as the crystal quality of CNTs grown can be changed and controlled by the application of substrate bias during CNT growth. It is for the first time observed that the prevailing growth mechanism of CNTs, which is either due to tip-driven growth or based-on-catalyst growth, may be influenced by substrate biasing. It is also seen that negative biasing would be more effectively role in the vertical-alignment of CNTs compared to positive biasing. However, the CNTs grown under the positively bias condition display much better electron emission capabilities than those grown under negative bias or without bias. The reasons for all the measured data regarding the structural properties of CNTs are discussed to confirm the correlation with the observed field-emissive properties.

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A Study for Revitalizing Program of Traditional Markets (재래시장 육성을 위한 특별법에서의 재래시장 활성화 실천방안 연구)

  • Kim Yong-Ho;Song Kyung-Soo
    • Management & Information Systems Review
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    • v.18
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    • pp.91-113
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    • 2006
  • Most merchant of traditional markets think that the condition of market management is getting worse because of decreasing customers caused appearance of large retail stores such as discount store and changing of consumer's life style. Therefore special law was legislated for the activation of traditional markets in 2005. This special law include important articles about surroundings improvement, business management modernization and redevelopment of traditional markets. According to the small and medium business administration data, korea government furnished 177billion and 11billion(won) separately for the facilities and management modernization of traditional markets. Traditional markets of whole country planned and practiced modernization of facilities and management of traditional markets. And most of traditional markets interested in a large project such as establishment of arcade and car parking, remodelling of building, pavement of passageway etc. By the way, under the long term viewpoint, a large project presented above are not the best solution for the traditional markets because of its effectiveness. Maybe, for example, improvement of store signboard and display stand is more effective for the long time. As the problem of management modernization, yet a credit transactions. is the most important factor, only four markets have a plan for the credit transactions. And above all, we must realize that activation of traditional markets can be accomplished by merchant's own initiative participation.

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