• Journal of Korean Neurosurgical Society
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• v.50 no.6
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• pp.486-491
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• 2011

Objective : Structural genetic variation, including copy-number variation (CNV), constitutes a substantial fraction of total genetic variability, and the importance of structural variants in modulating susceptibility is increasingly being recognized. CNV can change biological function and contribute to pathophysiological conditions of human disease. Its relationship with common, complex human disease in particular is not fully understood. Here, we searched the human genome to identify copy number variants that predispose to moya-moya type cerebrovascular disease. Methods : We retrospectively analyzed patients who had unilateral or bilateral steno-occlusive lesions at the cerebral artery from March, 2007, to September, 2009. For the 20 subjects, including patients with moyamoya type pathologies and three normal healthy controls, we divided the subjects into 4 groups : typical moyamoya (n=6), unilateral moyamoya (n=9), progression unilateral to typical moyamoya (n=2) and non-moyamoya (n=3). Fragmented DNA was hybridized on Human610Quad v1.0 DNA analysis BeadChips (Illumina). Data analysis was performed with GenomeStudio v2009.1, Genotyping 1.1.9, cnvPartition_v2.3.4 software. Overall call rates were more than 99.8%. Results : In total, 1258 CNVs were identified across the whole genome. The average number of CNV was 45.55 per subject (CNV region was 45.4). The gain/loss of CNV was 52/249, having 4.7 fold higher frequencies in loss calls. The total CNV size was 904,657,868, and average size was 993,038. The largest portion of CNVs (613 calls) were 1M-10M in length. Interestingly, significant association between unilateral moyamoya disease (MMD) and progression of unilateral to typical moyamoya was observed. Conclusion : Significant association between unilateral MMD and progression of unilateral to typical moyamoya was observed. The finding was confirmed again with clustering analysis. These data demonstrate that certain CNV associate with moyamoya-type cerebrovascular disease.

• Korean Journal of Plant Taxonomy
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• v.42 no.1
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• pp.13-23
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• 2012

The trnL-F region islocated in the large single-copy region of the chloroplast genome. It consists of the trnL gene, the trnL intron, and the trnL-F IGS. Molecular evolution and phylogenetic relationships in Korean Thalictrum L. were investigated using data from the cpDNA trnL-F region. Bayesian and parsimony analyses of the data set with the gap characteristics recovered well-resolved trees that are topologically similar, with clades supported by some indels evolution. Indel events of cpDNA trnL-F in Korean Thalictrum were interpreted as phylogenetically informative characteristics. Sect. Physocarpum (excluding T. osmorhizoides) was an early-diverging group with in the genus and the remaining section formed strongly supported clades. Korean Thalictrum has various evolutionary patterns, such as the spatial distribution of the nucleotide diversity and transversion-type base substitutions in the trnL-F region.

• Journal of Digital Contents Society
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• v.14 no.2
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• pp.247-254
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• 2013

Storage Class Memory(SCM), such as PRAM, FRAM and MRAM, are expected to be comparable to DRAM in terms of access speed and to Flash memory in terms of capacity in a near future. In this paper, assuming that not only the secondary storage (HDD or Flash memory) but also the primary memory (DRAM) will be replaced by SCM in the future computer systems, we propose an efficient file access framework for the SCM based computer systems. The proposed framework do not assign exclusive area in the SCM to the file system and uses various memory-related techniques, such as unified data access path, zero-copy data read using file mapping, copy-on-write, and multiple page pre-faulting for file management. Based on the preliminary experimental results, we could conclude that the proposed framework can be an efficient baseline for designing a new operating system for the SCM based computer systems.

• The Journal of the Korea institute of electronic communication sciences
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• v.16 no.6
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• pp.1145-1152
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• 2021

In order to optimize the performance of 1.4P large storage, the characteristics of each chunk mode were investigated, and the chunk 512K mode was selected in terms of I/O speed. NVME storage system was configured and used to measure data server performance of large storage. By measuring the change in throughput according to the number of threads of the 1.4P large storage, the characteristics of the large storage system were identified, and it was confirmed that the performance was up to 133Gbps with a block size of 32KB. As a result of data transmission/reception experiment using globus-url-copy of GridFTP, it was found that this large storage has a throughput of 33Gbps.

• Journal of the Korea Convergence Society
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• v.13 no.2
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• pp.21-29
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• 2022

Based on the importance of dialect research, preservation, and communication, this paper conducted a study on machine translation of Korean dialects for dialect users who may be marginalized. For the dialect data used, AIHUB dialect data distributed based on the highest administrative district was used. We propose a many-to-one dialect machine translation that promotes the efficiency of model distribution and modeling research to improve the performance of the dialect machine translation by applying Copy mechanism. This paper evaluates the performance of the one-to-one model and the many-to-one model as a BLEU score, and analyzes the performance of the many-to-one model in the Korean dialect from a linguistic perspective. The performance improvement of the one-to-one machine translation by applying the methodology proposed in this paper and the significant high performance of the many-to-one machine translation were derived.

• Korean Journal of English Language and Linguistics
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• v.2 no.3
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• pp.431-469
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• 2002

The main purpose of this paper is to present data about schm constructions in English and to examine them within the framework of Optimality Theory. American people sometimes reduplicate a word in deprecation using a prefix schm- or shm-, as in fancy-shmancy, and old-shmold. In these data, reduplicants surface as a copy of the whole word except the onset of the first syllable, which is replaced with schm. My data include some examples where the onset of the second syllable, not the first syllable, within the word reduplication is deleted and replaced with fixed segmentism schm, which seems to be infix rather than prefix. Above all, this study presents concrete evidence for the existence and function of ‘syllable’ and ‘foot’ known as prosodic categories by examining schm reduplication. Such extensions of schm-reduplcation also make predictions about types of outputs corresponding to their inputs.

• Proceedings of the KIEE Conference
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• 2000.07a
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• pp.203-205
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• 2000

The credibility and reliability of data is a very important issue in the protective relay setting which seriously influences the system security In this paper, DB management system which provides a convenient environment for various data handling such as data saving, retrieval, DB copy, DB update, DB editor and DB navigation using Web is explained. This paper also describes DB security adopted in the developed system.

• Journal of the Korea Society of Computer and Information
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• v.22 no.3
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• pp.1-8
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• 2017

In this paper, we propose a new hybrid wear leveling technique for NAND Flash memory, called Time-Aware Wear Leveling (TAWL). Our proposal prolongs the lifetime of NAND Flash memory by using dynamic wear leveling technique which considers the wear level of hot blocks as well as static wear leveling technique which considers the wear level of the whole blocks. TAWL also reduces the overhead of garbage collection by separating hot data and cold data using update frequency rate. We showed that TAWL enhanced the lifetime of NAND flash memory up to 220% compared with previous wear leveling techniques and our technique also reduced the number of copy operations of garbage collections by separating hot and cold data up to 45%.

• 한국정보통신설비학회:학술대회논문집
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• 2006.08a
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• pp.219-222
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• 2006

In this paper we present a cryptanalysis of the generalized patchwork algorithm under the assumption that the attacker possesses only a single copy of the watermarked audio. In the scheme, watermark is inserted by modifying randomly chosen DCT values in each block of the original audio. Towards the attack we first fit low degree polynomials (which minimize the mean square error) on the data available from each block of the watermarked content. Then we replace the corresponding DCT data of the at-tacked audio by the available data from the polynomials to construct an attacked audio. The technique nullifies the modification achieved during watermark embedding. Experimental results show that recovery of the watermark becomes difficult after the attack.

• Proceedings of the KIEE Conference
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• 2002.11b
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• pp.193-195
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• 2002

This paper presents the methods to solve the problem about Power System Protection Program(PROSET) and describe the database relation and schema with UML. PROSET is a overall program system to protect power system and correct it. In the context of the PROSET it is so difficult to edit database data when topology is changed. When the renewal of data is performed. all changed values are disappeared. Therefore, it will not be expected to know the present situation by using the information of the databases data. So it is necessary to solve this problem. Solution is copy of the user. Only E.R diagram is used to express database schema and relation. So, in this paper, UML(Unified Modeling Language) will be used to express PROSET and database of MCD-H and MDT-H.