• Journal of the Korean Association of Geographic Information Studies
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• v.9 no.1
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• pp.66-77
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• 2006

Considering constantly increasing number of internet users and information-oriented society with high speed internet network, the application of computer technology is considered to be valuable in urban planning. Particularly, since using Geographic Information System (GIS) is expected to be the best method to convey the information related to the urban planning. Therefore, this study aims at the development of participation system by using GIS and Internet. The system consists of Basic Module, Disposal Module and Decision Support Module. Each module is designed for expressing planning information and processing database, opinion statement and convenience of citizens, and the effectiveness of administration process and decision making. These are connected each other in a basic and simple form, i.e. Java Script and HTML, and the system was realized through data process, Map date and PostGIS for Mapping, and PHP. Last but not least, this system has been tested on the internet and the result indicated its convenience and availability in actual use concluding that participation system has enough application value on urban planning process.

• Perspectives in Nursing Science
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• v.7 no.1
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• pp.10-22
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• 2010

Purpose: Through a thorough examination of the CCSC (Community Comprehensive Support Center) system in Japan, this study suggests a scheme to provide community-based preventive health care services for the elderly in Korea. Methods: The study inquired into the applicability of the Japanese model by reviewing the data related to the CCSC project, aided by both in-depth interviews with staff in the field and consultations with specialists. Results: Rearrangement of the Visiting Health Management Project system is needed to manage the collective or individual visiting care management for frailty prevention of the elderly in communities. The delegated service system for preventive care in the community, including direct management by one of the public health centers, also needs to be reviewed and the application of stricter standards for the selection of the agency or corporation to run the delegated service is necessary. Long-Term Care Insurance, along with national and local grants, is to be considered as a financial resource for the community-based preventive health care model for the elderly. By making active use of education rooms at district offices, senior citizen centers in neighborhoods for the elderly with easy access can be created. The project needs to raise active supports from communities, develop programs which can be absorbed into particular local cultures, and promote the understanding of the preventive project in local communities. The preventive program should focus on first solving the problems of depression, seclusion, and lack of mobility of the elderly. Second, the program should instruct physical self-management for exercise-nutrition-dental maintenance, and third, the program should strengthen the cognitive abilities of the elderly. In addition, it is necessary to systematize and implement counter-plans of the family and community to protect the elderly who has mental and cognitive problems. Finally, by establishing a network of public health welfare resources based upon research on a community level, assessment and planning for the health of the elderly should be one with their family, and comprehensive consultation and recommendations should be provided to the family. Conclusion: Taking into consideration the experience Japan has had with respect to a similar project, it is appropriate to develop and implement a service system which would combine the Visiting Health Management Project system which has already been established and a preventive health care model for the elderly on a community level.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.24 no.4
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• pp.191-198
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• 2013

Objectives : The objective of this study is to find out the differences in psychopathology, temperament, and character factors between young adults with and without childhood attention-deficit hyperactivity disorder (ADHD) symptoms. Methods : The subjects consisted of 314 university students (male=72, female=242) in Gongju. They were divided into childhood ADHD group (N=54) and normal group (N=260) to the Wender-Utah Rating Scale. Participants were assessed using Korean Adult ADHD Scale, Beck Depression Inventory-II, Beck Anxiety Inventory, Kimberly Young's Internet Addiction Test, Barratt Impulsiveness Scale, Paranoia Scale, Korean-Schizotypal Ambivalence Scale, Lubben Social Network Scale, and Temperament and Character Inventory-Revised. Descriptive statistics, t-test, chi-square, spearman correlation, and stepwise multiple regression were applied to analyze the data. Results : Participants with childhood ADHD symptoms had high level of adult ADHD symptoms (p<.001), impulsiveness (p=.001), depression (p<.001), anxiety (p<.001), internet addiction (p<.001), paranoia tendency (p<.001) and low level of selfesteem (p<.001) compared to normal group. Self-directedness (p<.001) was lower, Harm avoidance (p=.001) and Self-transcendence (p=.029) were higher in the childhood ADHD group. In correlation and stepwise multiple regression, childhood ADHD symptoms were significantly associated with cooperativeness (r=-0.515 and ${\beta}$=-0.547, p<.001 respectively). Conclusion : This result showed that young adults with childhood ADHD symptoms had various forms of psychopathology and childhood ADHD symptoms were influenced by character such as cooperativeness. Therefore, more thorough evaluation regarding childhood ADHD symptoms is needed.

• IMMUNE NETWORK
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• v.11 no.5
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• pp.258-267
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• 2011

Background: Current management strategies attempt to diagnose rheumatoid arthritis (RA) at an early stage. Transcription profiling is applied in the search for biomarkers for detecting early-stage disease. Even though gene profiling has been reported using several animal models of RA, most studies were performed after the development of active arthritis, and conducted only on the peripheral blood and joint. Therefore, we investigated gene expression during the initial phase of collagen-induced arthritis (CIA) before the arthritic features developed in the thymus in addition to the peripheral blood and synovium. Methods: For gene expression analysis using cDNA microarray technology, samples of thymus, blood, and synovium were collected from CIA, rats immunized only with type II collagen (Cll), rats immunized only with adjuvant, and unimmunized rats on days 4 and 9 after the first immunization. Arrays were scanned with an Illumina bead array. Results: Of the 21,910 genes in the array, 1,243 genes were differentially expressed at least 2-fold change in various organs of CIA compared to controls. Among the 1,243 genes, 8 encode T-cell receptors (TCRs), including CD3${\zeta}$, CD3${\delta}$, CD3${\varepsilon}$, CD8${\alpha}$, and CD8${\beta}$ genes, which were down-regulated in CIA. The synovium was the organ in which the genes were differentially expressed between CIA and control group, and no difference were found in the thymus and blood. Further, we determined that the differential expression was affected by adjuvant more than Cll. The differential expression of genes as revealed by real-time RT-PCR, was in agreement with the microarray data. Conclusion: This study provides evidence that the genes encoding TCRs including CD3${\zeta}$, CD3${\delta}$, CD3${\varepsilon}$, CD8${\alpha}$, and CD8${\beta}$ genes were down-regulated during the initial phase of CIA in the synovium of CIA. In addition, adjuvant played a greater role in the down-regulation of the CD3 complex compared to CII. Therefore, the down-regulation of TCR gene expression occurred dominantly by adjuvant could be involved in the pathogenesis of the early stage at CIA.

• IMMUNE NETWORK
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• v.1 no.2
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• pp.135-142
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• 2001

Background: A large number of diseases occur in association with specific HLA-B or-C alleles. Recently a new gene, termed maj or histocompatibility complex class I chain-related gene A (MICA), has been identified in close proximity to HLA-B. The function of this gene is still unknown. However, it is structurally similar to HLA class I genes. MICA gene is polymorphic and is potentially associated with several diseases. Methods: To evaluate the association of MICA gene in Korean patients with human immunodeficiency virus 1 (HIV-1) infections, Polymerase chain reaction-Sequence specific primer (PCR-SSP) was done for MICA alleles in the extracellular exons, and a microsatellite analysis for GCT repeat polymorphisms in the TM exon was also completed. Results: In 199 Korean healthy controls, 7 alleles were observed and the frequencies for each allele were MICA008 (44.7%), MICA0 10 (34.2%), MICA002 (31.7%), MICA004 (23.6%), MICA0 12 (2 1.6%), MICA009 (19.6%), and MICA007 (6.5%). When 65 HIV seropositive patients were analyzed, MICA007 allele frequency was significantly higher than in controls (15.4% vs 6.5 %, RR=2.6, p<0.04). In contrast, the frequencies of other MICA alleles and microsatellite alleles in the transmembrane region of MICA gene were not significantly different between HIV seropositive patients and controls. The tight linkage between MICA alleles in the extracellular exons and GCT repeat polymorphisms in the TM exon was observed as follows; MICA002/A9, MICA004/A6, MICA007/A4, MICA008/A5.1, MICA0 10/A5, and MICA0 12/A4 in both groups. No significant difference between patients and controls was observed in the haplotype frequencies of MICA alleles in the extracellular exons and GCT repeat polymorphisms in the TM exon. Conclusion: The data suggest that immune functions related with MICA gene may affect a HIV infections.

• Journal of Korean Society of Transportation
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• v.23 no.8 s.86
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• pp.31-42
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• 2005

Accessibility is the generalized definition on how ease of access. Accessibility is used to appraise transportation project such as capturing the quality of the existing state of the transportation system at diverse spatial levels, It also reflects on the effect of improvements to the existing travel modes and the intoduction of new modes. The overall goal of this study is to propose a measure of urban accessibility in Seoul which can analyze various behavior of travelers in the city and to present applications. In this study, we apply measures of accessibility which are developed by CTR(The Center for Transportation Research, the University of Texas at Austin) to construct the urban accessibility index applicable for explaining trip behavior in Seoul. We evaluate sustainability of urban transport system in Seoul in 2002 by using the MAG(Modal Accessibility GaP) index which is developed to measure the accessibility gap between the more energy-efficient mode and less energy-efficient mode of transport. By analyzing the change of MAG index between 2002 and 2004 based on network data, we show how the public transportation system reform affect the sustainability in transport system.

• IMMUNE NETWORK
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• v.3 no.1
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• pp.16-22
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• 2003

Background: The S100A2 gene, also known as S100L or CaN19, encodes a protein comprised of 99-amino acids, is a member of the calcium-binding proteins of EF-hand family. According to a recent study, this gene was over-expressed in several early and malignant carcinomas compared to normal tissues. To elucidate the role of S100A2 protein in the process during carcinogenesis, production of monoclonal antibody specific to the protein is essential. Methods: First, cDNA sequence coding for ORF region of human S100A2 gene was amplified and cloned into an expression vector to produce GST fusion protein. Recombinant S100A2 protein and subsequently, monoclonal antibody to the protein were produced. The specificity of anti-S100A2 monoclonal antibody was confirmed by immunoblot analysis of cross reactivity to other recombinant proteins of S100A family (GST-S100A1, GST-S100A4 and GST-S100A6). To confirm the relation of S100A2 to cervical carcinogenesis, S100A2 protein in early cervical carcinoma tissue was immunostained using the monoclonal antibody. Results: GST-S100A2 recombinant protein was purified by affinity chromatography and then fusion protein was cleaved and S100A2 protein was isolated. The monoclonal antibody (KK0723; Korean patent pending #2001-30294) to the protein was produced and the antibody did not react with other members of EF-hand family proteins such as S100A1, S100A4 and S100A6. Conclusion: These data suggest that anti-S100A2 monoclonal antibody produced in this study can be very useful for the early detection of cervical carcinoma and elucidation of mechanism during the early cervical carcinogenesis.

• Journal of Broadcast Engineering
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• v.14 no.5
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• pp.573-588
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• 2009

In this paper, we propose a novel video quality degradation monitoring scheme titled VR-VQMS(Visual Rhythm based Video Quality Monitoring Scheme) over an IPTV service prone to packet losses during network transmission. Proposed scheme quantifies the amount of quality degradation due to packet losses, and can be classified into a RR(reduced-reference) based quality measurement scheme exploiting visual rhythm data of H.264-encoded video frames at a media server and reconstructed ones at an Set-top Box as feature information. Two scenarios, On-line and Off-line VR-VQMS, are proposed as the practical solutions. We define the NPSNR(Networked Peak-to-peak Signal-to-Noise Ratio) modified by the well-known PSNR as a new objective quality metric, and several additional objective and subjective metrics based on it to obtain the statistics on timing, duration, occurrence, and amount of quality degradation. Simulation results show that the proposed method closely approximates the results from 2D video frames and gives good estimation of subjective quality(i.e.,MOS(mean opinion score)) performed by 10 test observers. We expect that the proposed scheme can play a role as a practical solution to monitor the video quality experienced by individual customers in a commercial IPTV service, and be implemented as a small and light agent program running on a resource-limited set-top box.

• Korean Security Journal
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• no.41
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• pp.185-212
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• 2014

This research examines the decentralization of al-Qaida and other Salafi-jihadist terrorist groups, which is a subject of intense debate in the West. Especially, this study focused on investigating the status and evolution of al Qa'ida and other two Salafi-jihadist groups, Boko Haram and the Islamic States. These terrorist groups are currently considered as the most active Salafi-jihadist terrorist groups leading today's decentralization from Al-Qaida central terrorism network. This study also aims to examine the contemporary threats posed by the two extremely violent jihadist terrorist groups and these groups's terrorist networks. In order to achieve the purpose of this study, this study conducted content analyses with a wide range of documents reporting about Salafi-jihadist terrorists groups. Also this study utilized GTD data set drwan from START centner to provide descriptive analyses regarding IS and Boko Haram's activities and threats. On the basis of analyses, this study argues that recently the threats posed by core al Qaida has been severely weakened. Further, the broader Salafi-jihadist movement has become more decentralized among four tiers: first, core al Qaida in Pakistan; second, formal al Qa'ida affiliated groups that have sworn allegiance to core al Qaida; a number of Salafi-jihadist groups that have committed to establishing an extremist Islamic emirate without sworn allegiance to al Qaida; third, individual followers and networks inspired by al Qaida and other Salafi-jihadist groups. In concusion and discussion, this study highlights the need for a long-term engagement counter terrorism strategy against Salifi-jihadist terrorists groups on behalf of the peace and security of the world society.

• Journal of the Institute of Electronics Engineers of Korea SC
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• v.48 no.2
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• pp.64-70
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• 2011

Portable artificial electronic nose (E-nose) system suffers from noisy fluctuation in surroundings such as temperature, vapor concentration, and gas flow, because its measuring condition is not controled precisely as in the laboratory. It is important to develop a simple and robust vapor recognition technique applicable to this uncontrolled measurement, especially for the portable measuring and diagnostic system which are expanding its area with the improvements in micro bio sensor technology. This study used a PDA-based portable E-nose to collect the uncontrolled vapor measurement signals, and applied the image matching algorithm developed in the previous study on the measured signal to verify its robustness and improved accuracy in portable vapor recognition. The results showed not only its consistent performance under noisy fluctuation in the portable measurement signal, but also an advanced recognition accuracy for 2 similar vapor species which have been hard to discriminate with the conventional maximum sensitivity feature extraction method. The proposed method can be easily applied to the data processing of the ubiquitous sensor network (USN) which are usually exposed to various operating conditions. Furthermore, it will greatly help to realize portable medical diagnostic and environment monitoring system with its robust performance and high accuracy.