• Title/Summary/Keyword: Dangol

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Theme Analysis of Foodservice Research on Dangol (단골에 관한 외식서비스의 연구 주제 분석)

  • Sunhwa Shin;Kyungsoo Han
    • Journal of the FoodService Safety
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    • v.5 no.1
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    • pp.12-18
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    • 2024
  • "Dangol" is a native Korean word originating from 18 century folklore. Dangol is often used as a keyword and term in consumer marketing and foodservice industry research. However, a variety of other terms have also been used to express the concept of Dangol, including loyalty, brand loyalty, Choongsung, Choongsung level, loyal customer, Dangol customer, Dangol intention, and store loyalty. Due to a lack of clear conceptualizations of Dangol, terms such as Dangol, Choongsung, and loyalty are often mixed in their use, even in a single study. This study confirmed whether Dangol is being used interchangeably with loyalty in domestic literature by applying an integrated literature review of studies found on Google Scholar. Of the studies that have been published since 1990, 219 studies were analyzed. The first analysis yielded eight research keywords related to Dangol. Dangol intention, Dangol doctor, and Dangol faith were the most commonly used at 18.2%, followed by Dangol customer and Dangol relationship at 13.6%. The second analysis yielded nine research keywords related to loyalty. Out of the 99 cases, loyalty program occurred most frequently at 46%, followed by loyalty at 20%. The third analysis yielded 22 research keywords related to Choongsung in total. Customer Choongsung was most frequent at 28%, followed by trademark Choongsung at 14%. Finally, the results of the content analysis on Dangol was summarized as "designated relationship for business transaction and the relationship between the seller", "the customer when a single transactional relationship is established continuously".

Development of Vaccine Delivery System and Challenges (백신 전달기술 개발 동향과 과제)

  • Jung, Hyung-Il;Kim, Jung-Dong;Kim, Mi-Roo;Dangol, Manita
    • KSBB Journal
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    • v.25 no.6
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    • pp.497-506
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    • 2010
  • Vaccine is a protective clinical measure capable of persuading immune system against infectious agents. Vaccine can be categorized as live attenuated and inactivated. Live attenuated vaccines activate immunity similar to natural infection by replicating living organisms whereas inactivated vaccines are either whole cell vaccines, eliciting immune response by killed organisms,or subunit vaccines, stimulating immunity by non-replicating sub cellular parts. The components of vaccine play a critical role in deciding the immune response mediated by the vaccine. The innate immune responds against the antigen component. Adjuvants represent an importantcomponent of vaccine for enhancing the immunogenicity of the antigens. Subunit vaccines with isolated fractions of killed and recombinant antigens are mostly co-administered with adjuvants. The delivery system of the vaccine is another essential component to ensurethat vaccine is delivered to the right target with right dosage form. Furthermore, vaccine delivery system ensures that the desired immune response is achieved by manipulating the optimal interaction of vaccine and adjuvantwith the immune cell. The aforementioned components along with routes of administration of vaccine are the key elements of a successful vaccination procedure. Vaccines can be administered either orally or by parenteral routes. Many groups had made remarkable efforts for the development of new vaccine and delivery system. The emergence of new vaccine delivery system may lead to pursue the immunization goals with better clinical practices.

Visualization of Multicolored in vivo Organelle Markers for Co-Localization Studies in Oryza sativa

  • Dangol, Sarmina;Singh, Raksha;Chen, Yafei;Jwa, Nam-Soo
    • Molecules and Cells
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    • v.40 no.11
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    • pp.828-836
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    • 2017
  • Eukaryotic cells consist of a complex network of thousands of proteins present in different organelles where organelle-specific cellular processes occur. Identification of the subcellular localization of a protein is important for understanding its potential biochemical functions. In the post-genomic era, localization of unknown proteins is achieved using multiple tools including a fluorescent-tagged protein approach. Several fluorescent-tagged protein organelle markers have been introduced into dicot plants, but its use is still limited in monocot plants. Here, we generated a set of multicolored organelle markers (fluorescent-tagged proteins) based on well-established targeting sequences. We used a series of pGWBs binary vectors to ameliorate localization and co-localization experiments using monocot plants. We constructed different fluorescent-tagged markers to visualize rice cell organelles, i.e., nucleus, plastids, mitochondria, peroxisomes, golgi body, endoplasmic reticulum, plasma membrane, and tonoplast, with four different fluorescent proteins (FPs) (G3GFP, mRFP, YFP, and CFP). Visualization of FP-tagged markers in their respective compartments has been reported for dicot and monocot plants. The comparative localization of the nucleus marker with a nucleus localizing sequence, and the similar, characteristic morphology of mCherry-tagged Arabidopsis organelle markers and our generated organelle markers in onion cells, provide further evidence for the correct subcellular localization of the Oryza sativa (rice) organelle marker. The set of eight different rice organelle markers with four different FPs provides a valuable resource for determining the subcellular localization of newly identified proteins, conducting co-localization assays, and generating stable transgenic localization in monocot plants.

Effect of Support Surface on Abdominal Muscle Thickness during Side Plank Exercise (사이드 플랭크 운동 시 지지면이 배근육 두께에 미치는 효과)

  • Oh, Sang-Kyu;Kim, Chang-Wook
    • Journal of The Korean Society of Integrative Medicine
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    • v.9 no.4
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    • pp.183-190
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    • 2021
  • Purpose : The purpose of this study was to investigate the effect of side planks on the muscle thickness of the core muscles, external oblique, internal oblique, and transverse abdominis, and this study was conducted to compare whether side plank exercise according to the application of various unstable support surfaces increases the thickness by activating the action of the muscles. Methods : The subjects of this study were 30 healthy adults and were randomly and equally assigned to three groups by a random number table. All subjects were divided into three groups according to the application of an unstable support surface during the side plank(Group A = stable support, Group B = one unstable support, Group C = two unstable supports). The side plank exercise was performed 30 minutes a day, 3 times a week for a total of 4 weeks. The muscle thickness of the core muscle was measured before the intervention, 2 weeks, 4 weeks, and 3 times in total. All measured data were comparatively analyzed by repeated measures ANOVA and one-way ANOVA. The statistical significance level was set to .05. Results : The results of this study were as follows : 1. All muscles showed an interaction between training period and group. 2. There was a significant difference between the groups at the 2 weeks and 4 weeks of the internal oblique and transverse abdominis muscle measurements. Conclusion : The thickness of the abdominal muscle increased during the side plank exercise according to the support surface, and the thickness of the abdominal muscle increased the most during the side plank exercise on the unstable support surface. Therefore, it is thought that the addition of an unstable support surface will provide a more effective therapeutic effect on the thickness change of the abdominal muscle during side plank exercise.

Magnaporthe oryzae Effector AVR-Pii Helps to Establish Compatibility by Inhibition of the Rice NADP-Malic Enzyme Resulting in Disruption of Oxidative Burst and Host Innate Immunity

  • Singh, Raksha;Dangol, Sarmina;Chen, Yafei;Choi, Jihyun;Cho, Yoon-Seong;Lee, Jea-Eun;Choi, Mi-Ok;Jwa, Nam-Soo
    • Molecules and Cells
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    • v.39 no.5
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    • pp.426-438
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    • 2016
  • Plant disease resistance occurs as a hypersensitive response (HR) at the site of attempted pathogen invasion. This specific event is initiated in response to recognition of pathogen-associated molecular pattern (PAMP) and subsequent PAMP-triggered immunity (PTI) and effector-triggered immunity (ETI). Both PTI and ETI mechanisms are tightly connected with reactive oxygen species (ROS) production and disease resistance that involves distinct biphasic ROS production as one of its pivotal plant immune responses. This unique oxidative burst is strongly dependent on the resistant cultivars because a monophasic ROS burst is a hallmark of the susceptible cultivars. However, the cause of the differential ROS burst remains unknown. In the study here, we revealed the plausible underlying mechanism of the differential ROS burst through functional understanding of the Magnaporthe oryzae (M. oryzae) AVR effector, AVR-Pii. We performed yeast two-hybrid (Y2H) screening using AVR-Pii as bait and isolated rice NADP-malic enzyme2 (Os-NADP-ME2) as the rice target protein. To our surprise, deletion of the rice Os-NADP-ME2 gene in a resistant rice cultivar disrupted innate immunity against the rice blast fungus. Malic enzyme activity and inhibition studies demonstrated that AVR-Pii proteins specifically inhibit in vitro NADP-ME activity. Overall, we demonstrate that rice blast fungus, M. oryzae attenuates the host ROS burst via AVR-Pii-mediated inhibition of Os-NADP-ME2, which is indispensable in ROS metabolism for the innate immunity of rice. This characterization of the regulation of the host oxidative burst will help to elucidate how the products of AVR genes function associated with virulence of the pathogen.