• 한국습지학회지
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• 제21권4호
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• pp.290-297
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• 2019

하구는 하천이 개방해역과 연결되어 있어 담수와 염수가 만나는 전이지대로 생물다양성이 매우 높고 독특한 생태계를 구성하고 있다. 그러나 하구의 생태적 가치를 인식하기 전부터 다양한 훼손 및 교란이 이루어져 왔으며, 이를 위한 대책이 필요한 실정이다. 하구를 구성하는 하천의 하천기본계획은 지속적인 교란요소로 작용하고 있으나, 수재해로부터 인명피해를 최소화하고 하천의 기능을 강화시켜 국가 수자원을 관리하기 위한 공익적 목적이 있다. 따라서 개발과 생태계 보호라는 대립적 관계가 공존할 수 있는 방안에 대한 연구가 필요하다. 본 연구에서는 이를 위해서 환경창이라는 개념을 이용해 하구 생태계가 개발의 부정적인 영향으로부터 교란이 최소화되는 기간인 저영향 개발 기간을 산정하였다. 본 연구에서 제시한 저영향 개발 기간 산정방법은 향후 이루어질 개발사업이나 교란·훼손 행위 등으로부터 생태계를 보호하기 위한 근거 및 기초자료로 활용될 수 있을 것으로 판단된다.

• 융합신호처리학회논문지
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• 제17권2호
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• pp.71-76
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• 2016

디지털 영상처리는 의료산업, 위성사진, 공장자동화 영상인식 등 넓고 다양한 분양에 활용되고 있다. 하지만 이러한 영상 데이터는 처리, 전송, 저장하는 과정에서 여러 외부 원인에 의해 열화가 발생한다. 영상에 첨가되는 잡음에는 AWGN, salt and pepper 잡음이 대표적이다. AWGN에 훼손된 영상을 복원하기 위한 공간영역 방법에는 MF, CWMF, AWMF 등이 있으며, 기존의 방법들은 에지와 같은 상세 정보를 훼손하는 특성이 있다. 따라서 본 논문에서는 AWGN 환경에서 국부 마스크의 에지 크기에 따라 화소 방향에 따른 가중치 필터, 공간 가중치 필터 및 평균 필터의 가중치를 다르게 적용하는 알고리즘을 제안하였다. 그리고 제안한 알고리즘의 우수성을 입증하기 위해, PSNR을 사용하여 기존의 방법들과 그 성능을 비교하였다.

• 대한지역사회영양학회지
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• 제3권4호
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• pp.622-629
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• 1998

This study was performed to investigate the effect of dietary intakes and nutritional status for fatty liver male patients with fatty livers. General characteristics, nutritional knowledge, and dietary intakes were obtained from fatty liver male patients aged 20-60yr living in Seoul and Kyunggi province by individual interview and blood samples. The Results were as follows : the mean age of the subjects was 39yrs. Old and over half the subjects were overweight. Although nutritional knowledge, recognition, and accuracy scores were good, these did not affect the subject's health. The average alcohol intake of subjects was 79.8g/day and the drinking duration was 5-40yrs(average : 17yrs). The subjects drank alcohol over 4tiles/week and preferred Soju. Most side dishes taken with alcohol drinking by the subjects were foods from animal sources. Half of the subjects also drank alcohol the next day for breakfast as a hangover-chaser. The reasons for drinking were due to social relationships and by habit. Vitamin D and folate were lower than the RDA for Koreans, and other nutrient amounts were higher than the RDA. The amounts of aspartate amino-transferase(AST), Alanine amino-transferase(ALT), ${\gamma}$-glutamyl transpeptidase(${\gamma}$-GTP), Triglyceride(TG) for the subjects were higher. In conclusion, fatty liver patients drank excessively and frequently. It seems that heavy alcohol drinking is more prone to overweight or obese people and contributes to fatty livers. Therefore, the subjects need to be taken effectively educated about alcohol-induced liver damage and the importance of a balanced diet for on healthy liver.

• Preventive Nutrition and Food Science
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• 제1권1호
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• pp.134-142
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• 1996

Diabetes carries an increased risk of atherosclerotic disease that is not fully explained by known car-diovascular risk factors. There is accumulating evidence that advanced glycation of structural proteins, and oxidation and glycation of circulating lipoproteins, are implicated in the pathogenesis of diabetic ather-osclerosis. Reactions involving glycation and oxidation of proteins and lipids are believed to contribute to atherogenesis. Glycation, the nonenzymatic binding of glucose to protein molecules, can increase the ather-ogenic potential of certain plasma constituents, including low density lipoptotein(LDL). Glycation of LDL is significant increased in diabetic patients compared with normal subjects, even in the presence of good glycemic control. Metabolic abnormalities associated with glycation of LDL include diminished recognition of LDL by the classic LDL receptor; increased covalent binding of LDL in vessel walls ; enhanced uptake of LDL by the macrophages, thus stimulating foam cell formation ; increased platelet aggregation; formation of LDL-immune complexes ; and generation of oxygen free radicals, resulting on oxidative damage to both the lipid and protein components of LDL and to any nearby macromolecules. Oxidized lipoproteins are characterzied by cytotoxicity, potent stimulation of foam cell formation by macrophages, and procoagulant effects. Combined glycation and oxidation, "glycoxidation" occurs when oxidative reactions affect the initial products of glycation, and results in irreversible structural alterations of proteins. Glycoxidation is of greatest significance in long lived proteins such as collagen. In these proteins, glycoxidation products, believed to be atherogenic, accumulate with advancing age : in diabetes, their rate of accumulate is accelerated. Inhibition of glycation, oxidation and glycoxidation may form the basis of future antiaterogenic strategies in both diabetic and nondiabetic individuals.dividuals.

• 한국구조물진단유지관리공학회 논문집
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• 제25권6호
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• pp.121-130
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• 2021

최근 국내 소규모취약시설은 시설물의 노후화가 가속되고, 다양한 안전사고 발생 및 이용빈도 증가 등에 따라 안전 및 유지관리에 대한 새로운 접근과 인식의 필요성이 제기되고 있다. 특히 대부분의 사회복지시설을 포함하는 소규모취약시설은 안전취약계층의 다수가 이용하는 시설로 안전관리의 중요성이 매우 높다. 이에 본 연구에서는 국내 소규모취약시설을 대상으로 최근 13년간(2008년~2020년) 수행한 안전점검 결과(총 31,114개소)를 토대로 다양한 현황을 조사하였고, 데이터기반의 분야별 특성과 안전 및 유지관리에 관한 성과수준을 평가하였다. 이는 향후 국내 소규모취약시설의 안전기준 개선, 유지관리 전략 등 기초자료로 활용하고자 하며, 취약계층 대상 이용시설의 안전관리 강화에 대한 정책적 방향성을 제시하고자 한다.

• 한국의류산업학회지
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• 제21권3호
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• pp.318-325
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• 2019

This study analyzes current self-nail tips and nail-tip satisfaction. The study method selected from 3 domestic and 3 overseas companies analyzed current self-nail tips based on brand recognition and sales rate. A questionnaire was conducted on 261 adult women in their 20s and 50s about the satisfaction of nail care and self-nail tips. The results are as follows. As a result to analyze the current nail tips, there were products that did not contain the type of nail tip or the composition and ingredients of the glue. An online survey of the sizes of the current nail tips indicated differences in the sizing system method and that the presented sizes are different. The response rate was the highest for the survey results on why self-nail tips were preferred for respondents who prefer self-nail tips because the price was cheap. The reason why they did not prefer self-nail tips was that the degree of completeness was lower and the fitness was not good. In addition, it showed a high response rate in that the adhesive strength was poor and the size did not fit the nails. Therefore, it is necessary to develop a size for nail types by ergonomic design and develop a self-nail tip that can reduce nail damage.

• BMB Reports
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• 제52권6호
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• pp.373-378
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• 2019

The nucleotide-binding and oligomerization domain (NOD) is an innate pattern recognition receptor that recognizes pathogen- and damage-associated molecular patterns. The 29-kDa amino-terminal fibronectin fragment (29-kDa FN-f) is a matrix degradation product found in the synovial fluids of patients with osteoarthritis (OA). We investigated whether NOD2 was involved in 29-kDa FN-f-induced pro-catabolic gene expression in human chondrocytes. The expression of mRNA and protein was measured using quantitative real-time polymerase chain reaction (qrt-PCR) and Western blot analysis. Small interfering RNAs were used for knockdown of NOD2 and toll-like receptor 2 (TLR-2). An immunoprecipitation assay was performed to examine protein interactions. The NOD2 levels in human OA cartilage were much higher than in normal cartilage. NOD1 and NOD2 expression, as well as pro-inflammatory cytokines, including interleukin-1beta (IL-$1{\beta}$) and tumor necrosis factor-alpha (TNF-${\alpha}$), were upregulated by 29-kDa FN-f in human chondrocytes. NOD2 silencing showed that NOD2 was involved in the 29-kDa FN-f-induced expression of TLR-2. Expressions of IL-6, IL-8, matrix metalloproteinase (MMP)-1, -3, and -13 were also suppressed by TLR-2 knockdown. Furthermore, NOD2 and TLR-2 knockdown data demonstrated that both NOD2 and TLR-2 modulated the expressions of their adaptors, receptorinteracting protein 2 (RIP2) and myeloid differentiation 88, in 29-kDa FN-f-treated chondrocytes. 29-kDa FN-f enhanced the interaction of NOD2, RIP2 and transforming growth factor beta-activated kinase 1 (TAK1), an indispensable signaling intermediate in the TLR-2 signaling pathway, and activated nuclear factor-${\kappa}B$ (NF-${\kappa}B$), subsequently leading to increased expressions of pro-inflammatory cytokines and cartilage-degrading enzymes. These results demonstrate that 29-kDa FN-f modulated pro-catabolic responses via cross-regulation of NOD2 and TLR-2 signaling pathways.

• 한국자원공학회지
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• 제55권6호
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• pp.614-623
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• 2018

최근 한반도 남동부에서 발생한 연이은 강진들로 인해 국내에서도 지진 방재에 대한 관심도가 높아지고 있다. 본 연구에서는 최근 들어 급격히 진보하고 있는 시각지능과 가상현실 분야 기술들을 기반으로 하는, 맞춤형 지진재해 대응을 위한 기술적 방법론에 대해 살펴보고자 한다. 해당 기술은 카메라를 이용한 생활공간 영상 정보의 취득, 개별 객체의 영상 기반 인식, 3차원 공간 정보의 추출, 이산요소법 등을 활용한 가상 지진의 동역학적 모의, 가상현실환경에서의 모의 지진 실감화 등의 단계를 통해 구성된다. 본 연구에서는 이러한 전체 기술 프로세스를 구성하기 위한 각 단계의 프로세스, 해당 이슈와 관련한 현재 기술 동향, 실시를 위한 기술적 해결 과제 등을 분석하였다.

• 대한토목학회논문집
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• 제41권3호
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• pp.317-325
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• 2021

1988년 부산에서 처음 발병된 소나무재선충병(Pine Wilt Disease, PWD)은 우리나라 소나무에 막대한 피해를 주고 있는 심각한 질병이다. 정부에서는 2005년 소나무재선충병 방제특별법을 제정하고 피해지역의 소나무 이동 금지와 방제를 시행하고 있다. 하지만, 기존의 예찰 및 방제방법은 산악지형에서 동시다발적이고 급진적으로 발생하는 소나무재선충병을 줄이기에는 물리적, 경제적 어려움이 있다. 따라서 본 연구에서는 소나무재선충병 감염의심목을 효율적으로 탐지하기 위해 무인항공기를 이용한 영상자료를 바탕으로 딥러닝 객체인식 예찰 방법의 활용가능성을 제시하고자 한다. 소나무재선충병 피해목을 관측하기 위해서 항공촬영을 통해 영상 데이터를 획득하고 정사영상을 제작하였다. 그 결과 198개의 피해목이 확인되었으며, 이를 검증하기 위해서 접근이 불가한 급경사지나 절벽과 같은 곳을 제외하고 현장 조사를 진행하여 84개의 피해목을 확인할 수 있었다. 검증된 데이터를 가지고 분할방법인 SegNet과 검출방법인 YOLOv2를 이용하여 분석한 결과 성능은 각각 0.57, 0.77로 나타났다.

• Nutrition Research and Practice
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• 제16권2호
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• pp.173-193
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• 2022

BACKGROUND/OBJECTIVES: Alzheimer's disease (AD) is one of the most representative neurodegenerative disease mainly caused by the excessive production of amyloid beta (Aβ). Several studies on the antioxidant activity and protective effects of Populus tomentiglandulosa (PT) against cerebral ischemia-induced neuronal damage have been reported. Based on this background, the present study investigated the protective effects of PT against cognitive impairment in AD. MATERIALS/METHODS: We orally administered PT (50 and 100 mg/kg/day) for 14 days in an Aβ_25-35-induced mouse model and conducted behavioral experiments to test cognitive ability. In addition, we evaluated the levels of aspartate aminotransferase (AST) and alanine aminotransferase (ALT) in serum and measured the production of lipid peroxide, nitric oxide (NO), and reactive oxygen species (ROS) in tissues. RESULTS: PT treatment improved the space perceptive ability in the T-maze test, object cognitive ability in the novel object recognition test, and spatial learning/long-term memory in the Morris water-maze test. Moreover, the levels of AST and ALT were not significantly different among the groups, indicating that PT did not show liver toxicity. Furthermore, administration of PT significantly inhibited the production of lipid peroxide, NO, and ROS in the brain, liver, and kidney, suggesting that PT protected against oxidative stress. CONCLUSIONS: Our study demonstrated that administration of PT improved Aβ_25-35-induced cognitive impairment by regulating oxidative stress. Therefore, we propose that PT could be used as a natural agent for AD improvement.