• The Journal of Korean Physical Therapy
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• 제18권4호
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• pp.1-9
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• 2006

Recently, several investigations revealed that after unilateral brain damage, movement abnormalities were exposed on the ipsilateral side as well as the upper extremity contralateral to the damaged hemisphere. Even the motor abilities had significantly recovered from ipsilateral motor deficits on not only simple sensoriomotor function, also clinical assessments since subacute stage, although could not completely returned. Such motor deficits were detected in a diversity of motor tasks depending on the interhemispheric specialization, further in clinical evaluation and a daily of activities. In the clinical features, muscular weakness, sensory loss and impaired manual dexterity were observed. In a laboratory experiment, there were increasing evidences that the kinematic processing deficits was founded in various-specific motor tasks, which ranged from simple basic element to complex tasks, such as tapping task, step-tracking, goal directional aiming task, and iso(and non-)directional interlimb coordination. In the point of view, the manifest understanding in related to ipsilateral deficits provide the clinicians with an important information for scientific management about brain injured patient's prognosis and therapeutic guidelines.

• Clinical and Experimental Pediatrics
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• 제53권1호
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• pp.14-20
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• 2010

Cytomegalovirus (CMV) is currently the most common agent of congenital infection and the leading infectious cause of brain damage and hearing loss in children. Symptomatic congenital CMV infections usually result from maternal primary infection during early pregnancy. One half of symptomatic infants have cytomegalic inclusion disease (CID), which is characterized by involvement of multiple organs, in particular, the reticuloendothelial and central nervous system (CNS). Moreover, such involvement may or may not include ocular and auditory damage. Approximately 90% of infants with congenital infection are asymptomatic at birth. Preterm infants with perinatal CMV infection can have symptomatic diseases such as pneumonia, hepatitis, and thrombocytopenia. Microcephaly and abnormal neuroradiologic imaging are associated with a poor prognosis. Hearing loss may occur in both symptomatic and asymptomatic infants with congenital infection and may progress through childhood. Congenital infection is defined by the isolation of CMV from infants within the first 3 weeks of life. Ganciclovir therapy can be considered for infants with symptomatic congenital CMV infection involving the CNS. Pregnant women of seronegative state should be counseled on the importance of good hand washing and other control measures to prevent CMV infection. Heat treatment of infected breast milk at $72{^{\circ}C}$ for 5 seconds can eliminate CMV completely.

• Structural Engineering and Mechanics
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• 제82권2호
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• pp.245-258
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• 2022

Many Structural Health Monitoring (SHM) methods have been proposed for structural damage diagnosis and prognosis. However, SHM for pinched hysteretic structures can be problematic due to the high level of nonlinearity. The model-free hysteresis loop analysis (HLA) has displayed notable robustness and accuracy in identifying damage for full-scaled and scaled test buildings. In this paper, the performance of HLA is compared with seven other SHM methods in identifying lateral elastic stiffness for a six-story numerical building with highly nonlinear pinching behavior. Two successive earthquakes are employed to compare the accuracy and consistency of methods within and between events. Robustness is assessed across sampling rates 50-1000 Hz in noise-free condition and then assessed with 10% root mean square (RMS) noise added to responses at 250 Hz sampling rate. Results confirm HLA is the most robust method to sampling rate and noise. HLA preserves high accuracy even when the sampling rate drops to 50 Hz, where the performance of other methods deteriorates considerably. In noisy conditions, the maximum absolute estimation error is less than 4% for HLA. The overall results show HLA has high robustness and accuracy for an extremely nonlinear, but realistic case compared to a range of leading and recent model-based and model-free methods.

• Investigative Magnetic Resonance Imaging
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• 제10권1호
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• pp.8-15
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• 2006

목적 : 저산소성 뇌손상의 자기공명영상(MR) 소견을 유병기간 및 예후와 연관 지어 알아보고자 하였다. 대상 및 방법 : 임상적으로 저산소성 뇌손상으로 진단된 환자 18명의 19예의 MR을 대상으로 분석하였다. MR은 저산소증 발생 후 1일에서 20일(평균 8.6일)사이에 시행되었으며, 대상환자의 T1 및 T2 강조영상에서 비정상 고신호강도 병변의 위치, 뇌부종의 동반 유무 및 시간경과와 예후에 따른 병변의 양상을 분석하였다. 결과 : 전체 19예의 MR영상에서, T2 강조영상에서의 고신호강도 병변은 기저핵(15예, 78.9%), 뇌피질(13예, 68.4%), 뇌백질(9예, 47.4%), 시상(6예, 31.6%), 소뇌(4예, 21.1%), 뇌간(1예, 5.3%)의 순으로 관찰되었다. 뇌피질의 병변은 모든 경우 심부회색질에도 이상소견을 동반 하였으며 양측성, 미만성의 병변을 보였고, 뇌피질 대부분 또는 두정 후두엽에 국한되어 나타났다. 뇌피질 및 심부회색질의 T2 강조영상에서의 고신호는 급성기(6일이내)부터 아급성기(6일이후)에 걸쳐 1예를 제외한 전 예에서 다양한 정도로 있었다. 뇌간이나 소뇌의 침범은 비교적 드물었고 모두 뇌피질의 병변이 동반되어 관찰되었다. 뇌백질의 병변도 대부분 아급성기에 뇌피질과 심부회색질의 병변이 있을 때 발생했지만 양측성 분수경계역 뇌경색의 소견으로 단독 침범한 경우도 1예 있었다. T1 강조영상에서의 고신호강도 병변은 뇌피질 및 심부회색질에 주로 아급성기에 관찰되었으나, 급성기에도 일부 관찰되었다. 뇌부종은 11예에서 급성기, 아급성기에 걸쳐 관찰되었다. 의식이 회복된 환자의 MR에서 뇌피질의 침범이나 뇌부종의 빈도가 적었다. 결론 : 저산소성 뇌손상의 MR소견은 다양하지만, 거의 대부분 뇌피질과 심부 뇌회색질을 침범하는 양측성 미만성의 병변으로 나타났다. 뇌백질의 병변은 아급성기 이후에 주로 나타나나 급성기의 혹은 단독의 병변으로도 나타날 수 있다. 뇌피질의 침범정도가 경미하거나 뇌부종이 미약한 경우 예후가 좋았다.

• 대한소아치과학회지
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• 제32권1호
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• pp.33-39
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• 2005

매복된 상악 견치를 위한 외과적 수술을 동반하는 교정치료는 주위조직에 손상을 주지 않고 치열궁내에 적절히 위치시켜야 한다. 이를 위해 매복된 치아의 위치에 따라 다양한 외과적, 교정적 방법이 소개되었으며, 그 방법으로 window procedure, apically positioned flap, closed eruption technique, tunnel traction 등이 있다. 깊은 골연하 매복에서 사용할 수 있는 방법으로 closed eruption technique 그리고 tunnel traction이 있는데, closed eruption technique은 점막 및 치은 하방으로 지나는 견인 와이어의 자극으로 염증 발생 가능성이 높으며 치은퇴축 및 부착 치은의 소실이 발생할 수 있다. 하지만, tunnel traction은 치아의 맹출이 터널을 통해서 유도되어 각화치은에 둘러싸인 채 치조골의 중앙으로 나오게 되므로 치은퇴축이나 치주부착의 소실 없이 적절한 각화치은을 얻을 수 있으며 매복치가 치조골의 중심부로 맹출함에 따라 생리적 맹출과 같은 효과 얻을 수 있다. 본 증례는 깊은 매복을 보이는 상악 견치를 tunnel traction을 이용한 치료를 보고한 것으로, 적절한 방향을 가지고 맹출하였으며 치은퇴축이나 부착치은의 소실이 발생하지 않았다.

• Journal of Korean Neurosurgical Society
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• 제39권4호
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• pp.271-276
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• 2006

Objective : Despite the recent progress that has been made in intracerebral monitoring, it is still difficult to quantify the exact extent of primary brain damage after severe head injury. In this work, we investigate the role of S-100B protein as a serum marker of brain damage after severe head injury. Methods : 21 patients with severe head injury [GCS score <9] were selected for this prospective study. A venous blood sample was taken as soon as possible after head injury and the serum concentration of S-100B protein was measured daily for five consecutive days. The serum level of S-100B protein was compared with the patients' outcome. The outcome was measured twice, at hospital discharge and after 6 months of follow-up using the Glasgow Outcome Scale[GOS]. Results : Those patients who died within two weeks [after head injury] had a significantly higher serum S-100B value than those who survived [median, 9.64ug/L versus 2.91ug/L]. Seven [78%] of the nine patients who died had a maximum S-100B value of 2ug/L or higher, while three [25%] of the twelve surviving patients showed a maximum S-100B protein value of more than 2ug/L [P<005]. Conclusion : These results indicate that S-100B protein appears to be the most reliable index for estimating the extent of brain damage.

• Journal of Korean Dental Science
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• 제9권2호
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• pp.63-68
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• 2016

Pressure root resorption can be observed during the eruption of permanent dentition, especially of the maxillary canines (affecting lateral incisors) and mandibular third molars (affecting mandibular second molars). Since the cause of root resorption of the adjacent affected teeth is evident, treatment simply involves extraction of the impacted tooth. However, there have been few reports on the prognosis of the remaining resorbed tooth, as dentists often choose to extract them when damage due to root resorption is observed. We report a case involving a tooth that was severely resorbed due to pressure from an adjacent impacted tooth. After extraction of the impacted tooth, the remaining tooth retained vital pulp and survived as a functional tooth.

• Journal of Trauma and Injury
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• 제29권1호
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• pp.33-36
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• 2016

Traffic accidents involving agricultural machinery have been decreasing, but mortality is still high due to a lack of safety devices such as seat belts. Furthermore, secondary damage, such as abdominal impalement injury caused by loaded materials, is more likely to occur, and this type of injury leads to a poor prognosis. Impalement with pipes is often more fatal than other penetrating injuries because the diameter of the pipe is usually larger in size than other loaded materials. We report a case of a 72-year-old man with secondary abdominal impalement injury caused by a scaffolding pipe following a traffic accident.

• Annals of Clinical Neurophysiology
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• 제19권2호
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• pp.148-150
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• 2017

Peripheral neuropathy associated with hyper-IgE-emia have been rarely reported. Here we present a 72-year-old man with acute motor axonal neuropathy who had relatively poor prognosis. The serum was weakly positive for IgG GQ1b and GT1a, and serum IgE was significantly elevated. He was transferred to a rehabilitation center with Medical Research Council grade 3 lower extremity weakness on admission day 65. We would suggest that hyper-IgE-emia may increase the magnitude and rate of neural damage in this case.

• 한국한의학연구원논문집
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• 제13권1호통권19호
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• pp.37-42
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• 2007

As the cholera was spread over the Joseon dynasty at 1821, Hwang Doyeon investigated the symptoms like diarrhea, vomiting, muscle cramp and so on, and he presented the cause of cholera as the damage of Primordial-gi caused by abnormal climate and Damp-heat made by taking inadequate foods. He regarded as of great importance the ordinary health condition by guessing the prognosis of the disease, and proposed how to make a diagnosis of dehydration by observing nails and toenails. To treat cholera, he presented the methods of Sipseon-bloodletting and Singwol-moxacautery, and mentioned compound herb remedies and single herbs like garlic etc. He wrote down Mulberry leaves and Argyi wormwood leaves as the preventor of cholera to emphasize the importance of prevention, and mentioned food contraindication in addition to keep from getting worse.