• Molecular & Cellular Toxicology
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• v.3 no.2
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• pp.107-112
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• 2007

o-Nitrotoluene is used to synthesize artificial dyes and raw materials of urethane resin. In this study, we have carried out in vitro genetic toxicity tests and microarray analysis to understand the underlying mechanisms and the mode of action of toxicity of onitrotoluene. TA1535 and TA98 cells were treated with o-nitrotoluene to test its toxicity by basic genetic toxicity test. Ames and two new in vitro micronucleus and COMET assays were applied using CHO cells and L5178Y cells, respectively. In addition, microarray analysis of differentially expressed genes in L5178Y cells in response to o-nitrotoluene was analyzed using Affymatrix genechip. The result of Ames test was that o-nitrotoluene treatment did not increase the mutations both in base substitution strain TA1535 and in frame shift TA98. o-Nitrotoluene has not increased micronuclei in CHO cells. But onitrotoluene increased DNA damage in L5178Y cell. Two-hundred two genes were initially selected as differentially expressed genes in response to o-nitrotoluene by microarray analysis and forty four genes among them were over 2 times of log fold changed. These forty four genes could be candidate biomarkers of genetic toxic action of o-nitrotoluene related to induction of mutation and/or induction of micronuclei and DNA damage. Further confirmation of these candidate markers related to the DNA damage will be useful to understand the detailed mechanism of action of o-nitrotoluene.

• Journal of the Korean Society of Environmental Restoration Technology
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• v.25 no.6
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• pp.51-64
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• 2022

Along with the urbanization, the risk of urban flooding due to climate change is increasing. Flood regulation, one of the ecosystem services, is implemented in the different level of function of flood risk mitigation by the type of ecosystem such as forests, arable land, wetlands etc. Land use changes due to development pressures have become an important factor in increasing the vulnerability by flash flood. This study has conducted evaluating the urban flood regulation service using InVEST UFRM(Urban Flood Risk Model). As a result of the simulation, the potential water retention by ecosystem type in the event of a flash flood according to RCP 4.5(10 year frequency) scenario was 1,569,611 tons in urbanized/dried areas, 907,706 tons in agricultural areas, 1,496,105 tons in forested areas, 831,705 tons in grasslands, 1,021,742 tons in wetlands, and 206,709 tons in bare areas, the water bodies was estimated to be 38,087 tons. In the case of more severe 100-year rainfall, 1,808,376 tons in urbanized/dried areas, 1,172,505 tons in agricultural areas, 2,076,019 tons in forests, 1,021,742 tons in grasslands, 47,603 tons in wetlands, 238,363 tons in bare lands, and 52,985 tons in water bodies. The potential economic damage from flood runoff(100 years frequency) is 122,512,524 thousand won in residential areas, 512,382,410 thousand won in commercial areas, 50,414,646 thousand won in industrial areas, 2,927,508 thousand won in Infrastructure(road), 8,907 thousand won in agriculture, Total of assuming a runoff of 50 mm(100 year frequency) was estimated at 688,245,997 thousand won. In a conclusion. these results provided an overview of ecosystem functions and services in terms of flood control, and indirectly demonstrated the possibility of using the model as a tool for policy decision-making. Nevertheless, in future research, related issues such as application of models according to various spatial scales, verification of difference in result values due to differences in spatial resolution, improvement of CN(Curved Number) suitable for the research site conditions based on actual data, and development of flood damage factors suitable for domestic condition for the calculation of economic loss.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.19 no.5
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• pp.611-617
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• 2018

The application of health monitoring, including a fault detection technique, is needed to secure the structural safety of large structures. A 2-step crack identification method for detecting the crack location and size of the beam structure is presented. First, a crack occurrence region was estimated using the modified Laplacian operator for the strain mode shape obtained from the distributed local strain data. The crack location and size were then identified based on the natural frequencies obtained from the acceleration data and the neural network technique for the pre-estimated crack occurrence region. The natural frequencies of a cracked beam were calculated based on an equivalent bending stiffness induced by the energy method, and used to generate the training patterns of the neural network. An experimental study was carried out on an aluminum cantilever beam to verify the present method for crack identification. Cracks were produced on the beam, and free vibration tests were performed. A crack occurrence region was estimated using the modified Laplacian operator for the strain mode shape, and the crack location and size were assessed using the natural frequencies and neural network technique. The identified crack occurrence region agrees well with the exact one, and the accuracy of the estimation results for the crack location and size could be enhanced considerably for 3 damage cases. The presented method could be applied effectively to the structural health monitoring of large structures.

• International Journal of Fluid Machinery and Systems
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• v.10 no.1
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• pp.40-46
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• 2017

Small valves including ball valves, gate valves and butterfly valves have been adopted in the fields of steam power generation, petrochemical industry, carriers, and oil tankers. Butterfly valves have normally been applied to fields where in narrow places installing the existing valves such as gate valves and ball valves have proven difficult due to the surrounding area and the heavier of these valves. Butterfly valves are used to control the mass flow of the piping system under low pressure by rotating the circular disk installed inside. The butterfly valve is benefitted by having simpler structure in which the flow is controlled by rotating the disc circular plate along the center axis, whereas the weight of the valve is light compared to the gate valve and ball valve above-mentioned, as there is no additional bracket supporting the valve body. The manufacturing company needs to acquire the performance and life test equipment, in the case of adopting the improving factors to detect leakage and damage on the seat of the valve disc. However, small companies, which are manufacturing the industrial valves, normally sell their products without the life test, which is the reliability test and environment test, because of financial and manpower problems. Furthermore, the failure mode analysis of the products failed in the field is likewise problematic as there is no system collecting the failure data on sites for analyzing the failures of valves. The analyzing and researching process is not arranged systematically because of the financial problem. Therefore this study firstly tried to obtain information about the failure data from the sites, analyzed the failure mode based on the field data collected from the customers, and then obtained field data using measuring equipment. Secondly, we designed and manufactured the performance and life test equipment which also have the real time monitoring system with the naked eye for the butterfly valves. The concept of this equipment can also be adopted by other valves, such as the ball valve, gate valve, and various others. It can be applied to variously sized valves, ranging from 25 mm to large sized valves exceeding 3000 mm. Finally, this study carries out the life test with square wave pressure, using performance and life test equipment. The performance found out that the failures from the real time monitoring system were good. The results of this study can be expanded to the other valves like ball valves, gate valves, and control valves to find out the failure mode using the real time monitoring system for durability and performance tests.

• Proceedings of the KOSOMBE Conference
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• v.1993 no.11
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• pp.89-92
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• 1993

In this article, we present and analyze the results of the three consecutive in vivo experiments of the LVAD to evaluate the function of the LVAD and the adverse effects on living animals. We applied the LVAD consecutively to three mongrel dogs and the circulation of the blood was assisted under the anesthesia. We used in general both the asynchronous mode and the synchronous mode to drive the LVAD. During the experiments we monitored the dogs with a polygraph to evaluate the function of the LVAD and the additional effects on the natural hearts. We also examined several clinical pathologic tests in order to see the effects of the LVAD to the red blood cells and the other internal organs. The dogs survived for two to there days. The LVAD assisted the circulatory system at the maximum assist flow rate of 3.0 1/min. Although the red blood cells of the dogs had mechanical damages by the LVAD to result in the hemolysis, the degree of the hemolysis was not so high and the damages caused by the hemolysis on the dogs were not serious. The myocardium of the first dog was gradually worsened and eventually failed. The damage of the myocardium was due to the asynchronous driving mode of the LVAD. The other organs did not have serious damages due to the application of the LVAD. The main purpose of this paper is to evaluate the results of the in vivo experiments of the LVAD and to find better ways to the application of the LVAD to human beings.

• Journal of Korean Tunnelling and Underground Space Association
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• v.24 no.6
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• pp.539-552
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• 2022

In the case of train stations, due to the specificity of underground spaces with limited smoke emissions, if appropriate removal equipment is not equipped, the damage caused by fire smoke may increase in the event of a fire. As a result, the need for measures to ensure the safety of evacuation of underground stations has been highlighted, and research for safe evacuation of platform users in case of fire is continuously being conducted at home and abroad. However, although the smoke removal area is currently divided by smoke boundary walls and platform screen doors (PSD) and installed in the train platform, standards for smoke removal methods (air supply or exhaust) for each fire removal area, that is, smoke removal mode, are not presented. In this study, fire analysis and evacuation analysis were performed to estimate the number of deaths and to derive F/N guidance in order to quantitatively evaluate the fire risk according to the fire station fire, and the total risk was the lowest in the case of fire area exhaust and supply to adjacent areas.

• Earthquakes and Structures
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• v.15 no.6
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• pp.667-685
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• 2018

In eccentrically braced steel frames (EBFs), the links are fuse members which enter inelastic phase before other structure members and dissipate the seismic energy. Based on the force-based seismic design method, damages and plastic deformations are limited to the links, and the main structure members are required tremendous sizes to ensure elastic with limited or no damage. Force-based seismic design method is very common and is found in most design codes, it is unable to determine the inelastic response of the structure and the damages of the members. Nowadays, methods of seismic design are emphasizing more on performance-based seismic design concept to have a more realistic assessment of the inelastic response of the structure. Links use ordinary steel Q345 (the nominal yielding strength $f_y{\geq}345MPa$) while other members use high strength steel (Q460 $f_y{\geq}460MPa$ or Q690 $f_y{\geq}690MPa$) in eccentrically braced frames with high strength steel combination (HSS-EBFs). The application of high strength steels brings out many advantages, including higher safety ensured by higher strength in elastic state, better economy which results from the smaller member size and structural weight as well as the corresponding welding work, and most importantly, the application of high strength steel in seismic fortification zone, which is helpful to popularize the extensive use of high strength steel. In order to comparison seismic behavior between HSS-EBFs and ordinary EBFs, on the basis of experimental study, four structures with 5, 10, 15 and 20 stories were designed by PBSD method for HSS-EBFs and ordinary EBFs. Nonlinear static and dynamic analysis is applied to all designs. The loading capacity, lateral stiffness, ductility and story drifts and failure mode under rare earthquake of the designs are compared. Analyses results indicated that HSS-EBFs have similar loading capacity with ordinary EBFs while the lateral stiffness and ductility of HSS-EBFs is lower than that of EBFs. HSS-EBFs and ordinary EBFs designed by PBSD method have the similar failure mode and story drift distribution under rare earthquake, the steel weight of HSS-EBFs is 10%-15% lower than ordinary EBFs resulting in good economic efficiency.

• Journal of Korea Water Resources Association
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• v.55 no.12
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• pp.1125-1135
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• 2022

Damages by heavy snow does not occur very often, but when it does, it causes damage to a wide area. To mitigate snow damage, it is necessary to know, in advance, the depth of snow that causes damage in each region. However, snow depths are measured at observatory locations, and it is difficult to understand the spatial distribution of snow depth that causes damage in a region. To understand the spatial distribution of snow depth, the point measurements are interpolated. However, estimating spatial distribution of snow depth is not easy when the number of measured snow depth is small and topographical characteristics such as altitude are not similar. To overcome this limit, satellite images such as Synthetic Aperture Radar (SAR) can be analyzed using Differential Interferometric SAR (DInSAR) method. DInSAR uses two different SAR images measured at two different times, and is generally used to track minor changes in topography. In this study, the spatial distribution of snow depth was estimated by DInSAR analysis using dual polarimetric IW mode C-band SAR data of Sentinel-1B satellite operated by the European Space Agency (ESA). In addition, snow depth was estimated using geostationary satellite Chollian-2 (GK-2A) to compare with the snow depth from DInSAR method. As a result, the accuracy of snow cover estimation in terms with grids was about 0.92% for DInSAR and about 0.71% for GK-2A, indicating high applicability of DInSAR method. Although there were cases of overestimation of the snow depth, sufficient information was provided for estimating the spatial distribution of the snow depth. And this will be helpful in understanding regional damage-causing snow depth.

• Earthquakes and Structures
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• v.4 no.4
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• pp.429-449
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• 2013

Current Design Codes for Reinforced Concrete (RC) interior beam-column joints are based on limited experimental studies on the seismic behavior of eccentric joints. To supplement existing information, an experimental study was conducted that focused on the effect of eccentricity of the deeper beams with respect to the shallow beams. A total of eight one-third scale interior joints with beams of different depths were subjected to reverse cyclic loading. The primary variables in the test specimens were the amount of joint transverse reinforcement and the cross section of the shallow beams. The overall performance of each test assembly was found to be unsatisfactory in terms of joint shear strength, stiffness, energy dissipation and shear deformation. The results indicated that the vertical eccentricity of spandrel beams in this type of joint led to lower capacity in joint shear strength and severe damage of concrete in the joint core. Increasing the joint shear reinforcement was not effective to alter the failure mode from joint shear failure to beam yielding which is favorable for earthquake resistance design, whereas it was effective to reduce the crack width at the small loading stages. Based on the observed behavior, the shear stress of the joint core was suggested to be kept as low as possible for a safe and practical design of this type of joint.

• Journal of Welding and Joining
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• v.30 no.6
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• pp.36-41
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• 2012

General condensers consist of many tubes supported by tube sheets and support plates to prevent the deflection of the condenser tubes. When a fluid at high pressure and temperature runs over the tubes for the purpose of transferring heat from one medium to another, the tubes vibrate and their surface comes into contact with the support plates. This vibration causes damage to the tubes, such as cracks and wear. We propose an ultrasonic guided wave technique to detect the above problems in the support plate region. In the proposed method, the ultrasonic guided wave mode, L(0,1), is excited using an internal transducer probe from a single position at the end of the tube. In this paper, we present a preliminary experimental verification using a super stainless tube and show that the defects can be discriminated from the support signals in the support region.