• Proceedings of the Korean Magnestics Society Conference
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• 2004.12a
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• pp.213-214
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• 2004

• Journal of the Korean Society of Costume
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• v.52 no.6
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• pp.1-13
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• 2002

This paper investigated the costumes of young girl dancers in Yon wha dae moo(연화대무: Lotus Stage dance) which were documented on the Ak-hak-guae-bum(악학궤범: Protocol of music) and the Jin-yeon-eui-guae(진연의궤: Archives of Royal Feast). The fashion of the costumes can be changed into three phases, based mainly on the changes of Hap-rip(합립: silk hat), Dan-eui(단의: long jacket) and Sang(상: apron type skirt). In the first phase the costume consisted of Hap-rip, round neck-line Dan-eui and tiered skirt decorated with pleat and Yu-so(유소: decorated cords). In the second phase. it consisted of Hap-rip, v-shape neck-line Dan-eui and skirt without pleat. In the third phase, it consisted of Yeon-wha-gwan(연화관: Lotus shape cap), round neck-line Dan-eui of later era and skirt with pleat and Yu-so. Yon-wha-dae dance appears to be adopted from Ja-ji-mu( 자지무: chinese dance) that originated in West and Central Asia. In both dances. young girl dancers danced mainly jump and spin. The costume of round neck-line Dan-eui seems to have been affected by the fashion in Dang Dynasty when young girls loved to wear Dan-ryung(단령: male coat with round neckline). And it satisfied the need of mobility for the dance which was Performed mainly with jump.

• Journal of Oriental Neuropsychiatry
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• v.15 no.2
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• pp.103-118
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• 2004

Objective : This experiment was designed to investigate the effect of KongJin-dan(KJD) on the Alzheimer's disease. Method : The effects of KJD on $LI-1{\beta}$, IL-6, $TNF-{\alpha}$, amyloid precursor proteins(APP), acetylcholinesterase(AChE), glial fibrillary acidic protein(GFAP) mRNA of PC-12 and THP-1 cell treated by CT105 and AChE activity, APP production of PC-12 cell lysate treated by CT105 were investigated, respectively. Results : 1. KJD suppressed $LI-1{\beta}$, IL-6, $TNF-{\alpha}$, APP, AChE, GFAP mRNA in THP-1 and PC-12 cell treated by CT105. 2. KJD suppressed AChE activity and production of APP significantly in cell lysate of PC-12 cell treated by CT105. Conclusions : This study shows that KJD might be usefully applied for prevention and treatment of Alzheimer's disease.

• Biomolecules & Therapeutics
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• v.15 no.4
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• pp.245-251
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• 2007

The object of this study was to evaluate the single dose toxicity of Kong-Jin-Dan (KJD), a polyherbal formula in male and female mice. KJD was administered to female and male ICR mice as an oral dose of 2000, 1000 and 500 mg/kg (body wt.) according to the recommendation of KFDA Guidelines. Animals were monitored for the mortality and changes in body weight, clinical signs and gross observation during 14 days after dosing, upon necropsy, organ weight and histopathology of 12 principle organs were examined. As results, we could not find any mortality, clinical signs, and changes in the body and organ weight except for increases of lymphoid organ weights in KJD-dosing groups. These increases of lymphoid organ weights considered that related to the immune modulate effect of KJD not toxicological signs. In addition, no KJD-treatment related abnormal gross findings and changes in histopathology of principle organs were detected except for some sporadic accidental findings. The results obtained in this study suggest that the KJD does not cause any toxicological signs. The $LD_{50}$ and approximate LD of KJD extracts in both female and male mice were considered as over 2000 mg/kg.

• Proceedings of the Korean Environmental Sciences Society Conference
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• 2018.10a
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• pp.86-86
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• 2018

• Journal of Haehwa Medicine
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• v.16 no.1
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• pp.41-59
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• 2007

From the study of prescription on low back pain, the following conclusions are obtained. 1. Among classified cause of low back pain, ShinHur(腎虛) lowback pain and its prescription was most mentioned. 2. Prescriptions such as ChungAWhan(靑娥丸), KookBangAnShinWhan(局方安腎丸) BoSooDan(補髓丹) BaekBaeWhan(百倍丸) DooChungWhan(杜沖丸) JangBonDan(壯本丹) NokKakWhan(鹿角丸) were used in ShinHur(腎虛) type low back pain. 3. Prescription such as TaekRanTang(澤蘭湯) JiRyongSan(地龍散) YoeShinSan(如神散) ShinKookJoo(神麴酒) SoeGuenSan(舒筋散) were used in JwaSumJilBak(閃挫跌撲) type low back pain. 4. Prescription such as ChangChulTang(蒼朮湯) JumTongTang(拈痛湯) ChulBuTang(朮附湯) YiChoChangBaekSan(二炒蒼栢散) were used in SeupYoel(濕熱) type low back pain. 5. Prescription such as ChunGoongYookGaeTang(川芎肉桂湯) GaMiSaMulTang(加味四物湯) PaHoelSanDongTang(破血散疼湯) JiRyongSan(地龍散) were used in UhHoel(瘀血) type low back pain. 6. Prescription such as (蒼術復煎散) (五積散) (摩腰丹) (滲濕湯) were used in HanSeup(寒濕) type low back pain. 7. Prescription such as GaMiYiJinTang(加味二陳湯) GongYeonDan(控涎丹) SaMoolTangHapYiJinTangGaMi(四物湯合二陳湯加味) were used in DamUem(痰飮) type low back pain. 8. Prescription such as OhJukSanGaMi(五積散加味) OhYakSoonGiSanGaMi(烏藥順氣散加味) GaMiYongHoSan(加味龍虎散) SoSokMyoungTang(小續命湯) were used in Poong(風) type low back pain. 9. Prescription such as (四物湯合二陳湯) (仰腰湯) were used in SikJuk(食積) type low back pain and (五積散) (煨腎散) (三花神祐丸) in Seup(濕) type low back pain. 10. Prescription such as ChilKiTang(七氣湯) ChimHyangGangKiTang(沈香降氣湯) ChoKiSan(調氣散) InSamSoonKiSan(人參順氣散) were used in Ki(氣) type low back pain.

• The Journal of Korean Medical History
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• v.34 no.1
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• pp.31-46
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• 2021

Shin Hong-Gyun and his family have been in medicine for many generations as Korean Medical Doctors (KMDs). In 1919 when Shin Hong-Gyun was participating in an independence movement in Jang-Baek-Hyun, his younger brother Shin Dong-Gyun was killed by Japanese military police forces. This tragic incident triggered Shin Hong-Gyun to establish an army for national independence called , holding 200 young men, to serve in armed struggle against the Japanese Government with Kim Jung-Geon in May, 1920. In March 1933, Shin Hong-Gyun, as a military surgeon, led his men to the Korean Independence Army to fight a battle. Once he became a member of the Korean Independence Army, he, in fact, participated in few battles: Sadohaja, Dong-Kyung-Sung, Deajeonjayeong. Daejeonjayeong was a waypoint that the Japanese military needed to pass through in order to reach the Wangcheong area. Shin Hong-Gyun's independence forces had to endure painful starvation and heavy rain while hiding in ambush for long periods of time until the Japanese military would appear. Due to its summer rainy season, rainwater overflowed into their trenches and was filled up to the waist. Even worse, food stockpiles were low and the Japanese army did not appear for longer time. Shin Hong-Gyun's entire team suffered severe hunger and extreme cold. At this critical moment, Shin Hong-Gyun used his expertise as a KMD to find edible black mushrooms that grow wild in the mountains and use them to feed his men. This event led to the victory of the independence army at the battle of Daejeonjayeong. The purpose of the paper is to inform and highlight the forgotten history of Shin Hong-Gyun who was, both, a Korean Medical Doctor and a military surgeon.

• The Journal of Internal Korean Medicine
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• v.29 no.4
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• pp.1037-1047
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• 2008

Background : A traditional Oriental medicine, GongJjn-dan (GJD), is one of the most well-known tonic agents in Korea. Among 6 types of GJD components, antler, red ginseng, and Cornus fructus have shown antioxidant effects, while EtOH-induced tissue damage may be a consequence of oxidative stress. Objectives & Methods : The hepatoprotective effects of GJD were evaluated on EtOH-mediated experimental liver damaged rats at 50, 100, 250 and 500mg/kg comparing with 100mg/kg of silymarin as a reference drug in the present study. Test substances were dosed once a day for 60 days with oral administration of 20% ethanol 2.5ml/100g body weight twice a day (equivalent to 7.9g ethanol/kg/day). Each of 8 rats per group was selected using body weight at 10 days after acclimatization. Experimental animals were sacrificed after 60 days of continuous oral treatment of test substances with 20% ethanol treatment, and changes on the body weight, liver weight, and serum AST and ALT were observed. Results : There were dramatic decreases of body weight and increases of liver weight and serum AST and ALT. Similar inhibition effects on the EtOH-induced hepatic damages were detected between equal dosages of GJD and silymarin. Conclusion : Based on these results. it is concluded that GJD showed clear hepatoprotective effects on EtOH-induced hepatic damage.

• Journal of Oriental Neuropsychiatry
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• v.17 no.2
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• pp.91-122
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• 2006

Objective : This research investigates the effect of the Jangwon-Dan,(JWD) on Alzheimer's disease. Method : The effects of the JWN extract on (1) $IL-1{\beta}$, IL-6, and $TNF-{\alpha}$ mRNA of PC-12 cells treated with LPS; (2) amyloid precursor proteins(APP), acetylcholinesterase(AChE), and glial fibrillary acidic protein(GFAP) mRNA, the AChE activity and the APP production of PC-12 cell treated with CT-105; (3) the behavior; (4) expression of $IL-1{\beta}$, $TNF-{\alpha}$, MDA, $IL-1{\beta}$ mRNA, and $TNF-{\alpha}$ mRNA, (5) the infarction area of the hippocampus, and brain tissue injury in Alzheimer's diseased mice induced with ${\beta}A$ were investigated. Result : 1. The JWN extract suppressed the expression of $IL-1{\beta}$, IL-6 and $TNF-{\alpha}$ mRNA in THP-1 cells treated with LPS. 2. The JWN extract suppressed the expression of APP, AChE, and GFAP mRNA in PC-12 cells treated with CT-105. 3. The JWN extract suppressed the AChE activity, and the production of APP significantly in PC-12 cells treated with CT-105. 4. For the JWN extract group a significant inhibitory effect on the memory deficit was shown for the mice with Alzheimer's disease induced by ${\beta}A$ in the Morris water maze experiment, which measured stop-through latency, and distance movement-through latency. 5. The JWN extract suppressed the over-expression of $IL-1{\beta}$ protein, $TNF-{\alpha}$ protein, MDA, $IL-1{\beta}$ mRNA, $TNF-{\alpha}$ mRNA, and CD68/GFAP, in the mice with Alzheimer's disease induced by ${\beta}A$. 6. The JWN extract reduced the infarction area of hippocampus, and controlled the injury of brain tissue in the mice with Alzheimer's disease induced by ${\beta}A$. Conclusion : These results suggest that the JWN extract may be effective for the prevention and treatment of Alzheimer's disease. Investigation into the clinical use of the JWN extract for Alzheimer's disease is suggested for future research.

• Proceedings of the IEEK Conference
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• 2004.06b
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• pp.339-342
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• 2004

본 논문은 밀리미터파 대역 무선통신 시스템 송신부의 응용을 위해 CPW 구조를 이용하여 V-band용 상향 주파수 혼합기와 2단 구동증폭기를 설계$\cdot$제작하였다. 능동소자는 본 연구실에서 제작한 $0.1{\mu}m$ 게이트 GaAs Pseudomorphic HEMTs(PHEMTs)를 사용하였으며 입$\cdot$출력단은 CPW를 사용해 정합 회로를 설계하였다. 제작된 상향 주파수 혼합기는 LO power 5.4 dBm, 2.4 GHz IF 신호를 -10.25 dBm으로 입력하였을 때 Conversion Loss 1.25 dB, LO-to-RF Isolation은 58 GHz에서 13.2 dB의 특성을 나타내었다 2단 구동 증폭기는 측정결과 60 GHz에서 S21 이득 13 dB, $58\;GHz\;\~\;64\;GHz$ 대역에서 S21 이득 12 dB 이상을 유지하는 광대역 특성을 얻었고 증폭기의 Pl dB는 3.8 dBm, 최대 출력전력은 6.5 dBm의 특성을 얻었다.