• 제목/요약/키워드: Dae Hee Lee

검색결과 3,592건 처리시간 0.04초

Triterpenoids from Trapa pseudoincisa

  • Song, Myoung-Chong;Yang, Hye-Joung;Lee, Dea-Young;Ahn, Eun-Mi;Kim, Dae-Keun;Kim, Ji-Young;Chung, Dae-Kyun;Baek, Nam-In
    • Journal of Applied Biological Chemistry
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    • 제50권4호
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    • pp.259-263
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    • 2007

  • Trapa pseudoincisa Nakai, an aquatic plant, was extracted with 80% aqueous MeOH, and the concentrated extract was successively partitioned with EtOAc, n-BuOH, and $H_2O$. The EtOAc fraction gave three compounds, which were isolated through the repeated silica gel and ODS column chromatographies. Based on the spectroscopic data obtained from NMR, MS, and IR, the chemical structures of the compounds were determined as cycloeucalenol (1), ursolic acid (2), and 2${\beta}$,3${\alpha}$,23-trihydroxyurs-12-en-28-oic acid (3). These triterpenoids were isolated for the first time from Hydrocaryaceae plants including T. pseudoincisa NAKAI.

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조선시대 간의대 천문관측기기 개발자 (MANUFACTURERS OF ASTRONOMICAL INSTRUMENTS INVENTED DURING THE GANUI-DAE PROJECT IN JOSEON DYNASTY)

  • 민병희;이민수;최고은;이기원
    • 천문학논총
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    • 제31권3호
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    • pp.77-85
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    • 2016

  • We study the manufacturers of the astronomical instruments invented as part of the so-called Ganui-Dae (astronomical platform) project in the reign of King Sejong (1418-1450) of the Joseon dynasty. The main purpose of this project was to compile the Chiljeongsan-Naepyeon, a Korean calendar, that lasted for 5.5 years from 1432 to 1438. Through this project, a total of 17 astronomical instruments such as the armillary sphere, celestial globe, and auto-striking clepsydra were developed. It is generally known that most of them were manufactured by Lee Cheon (李蕆, 1376-1451) and Jang Yeong-Sil (蔣英實, fl. 1423-1442). In this study, we investigate the accounts of the Veritable Records of King Sejong, Munjong, and Sejo, focusing on the inscription written out to memorize the completion of the Ganui-Dae project. We found that at least 12 persons took part in manufacturing the astronomical instruments of the Ganui-Dae project. Lee Cheon was involved in the production of four instruments, while Jang Yeong-Sil was involved in two; therefore, it seems that the achievement of Jang Yeong-Sil was overestimated. We also found that Jeong Cho (鄭招, ?-1434) was a scientist and Lee Cheon was an engineer in the early phase of the Ganui-Dae project, while King Sejong and Yi Sun-Ji (李純之, 1406-1465) played major role in the late phase. According to our study, King Sejong and Yi Sun-Ji were involved in the production of at least seven and five instruments, respectively. In conclusion, we believe that this study will be helpful to understand the practical manufacturers of the astronomical instruments invented during the Ganui-Dae project in the Joseon dynasty.

  • https://doi.org/10.5303/PKAS.2016.31.3.077 인용 PDF KSCI

Anti-Inflammatory Effect of Flavonoids from Brugmansia arborea L. Flowers

  • Kim, Hyoung-Geun;Jang, Davin;Jung, Young Sung;Oh, Hyun-Ji;Oh, Seon Min;Lee, Yeong-Geun;Kang, Se Chan;Kim, Dae-Ok;Lee, Dae Young;Baek, Nam-In
    • Journal of Microbiology and Biotechnology
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    • 제30권2호
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    • pp.163-171
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    • 2020

  • Brugmansia arborea L. (Solanaceae), commonly known as "angel's trumpet," is widely grown in North America, Africa, Australia, and Asia. It has been mainly used for ornamental purposes as well as analgesic, anti-rheumatic, vulnerary, decongestant, and anti-spasmodic materials. B. arborea is also reported to show anti-cholinergic activity, for which many alkaloids were reported to be principally responsible. However, to the best of our knowledge, a phytochemical study of B. arborea flowers has not yet been performed. Four flavonol glycosides (1-4) and one dihydroflavanol (5) were for the first time isolated from B. arborea flowers in this study. The flavonoids showed significant antioxidant capacities, suppressed nitric oxide production in lipopolysaccharide (LPS)-treated RAW 264.7 cells, and reduced inducible nitric oxide synthase (iNOS) and cyclooxygenase (COX-2) protein production increased by LPS treatment. The contents of compounds 1-4 in n-BuOH fraction were determined to be 3.8 ± 0.9%, 2.2 ± 0.5%, 20.3 ± 1.1%, and 2.3 ± 0.4%, respectively, and that of compound 5 in EtOAc fraction was determined to be 12.7 ± 0.7%, by HPLC experiment. These results suggest that flavonol glycosides (1-4) and dihydroflavanol (5) can serve as index components of B. arborea flowers in standardizing anti-inflammatory materials.

  • https://doi.org/10.4014/jmb.1907.07058 인용 PDF KSCI