• Title/Summary/Keyword: DTX

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Analysis of Heavy Metal Contamination and Shellfish Poisoning Toxins in Marketed Shellfishes (유통 패류의 중금속 및 패류독소 분석)

  • Kim, Jeong-Eun;Hwang, Seon-Il;Lee, Seong-Bong;Shin, Sang-Woon;Kwon, Hye-Jung;Lee, Ji-Yeon;Lee, Byoung-Hoon;Mo, A-Ra;Choi, Ok-Kyung
    • Journal of Food Hygiene and Safety
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    • v.37 no.3
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    • pp.159-165
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    • 2022
  • In this study, heavy metals (lead, cadmium, and mercury) and shellfish poisoning toxins (diarrhetic shellfish poisoning toxins, amnesic shellfish poisoning toxins) were investigated in a total of 104 shellfishes. According to the analysis of heavy metals, lead (Pb) was detected in the range of 0.0177-0.5709 mg/kg, cadmium (Cd) was detected in the range of 0.0226-1.4602 mg/kg, and mercury (Hg) was detected in the range of 0.0015-0.0327 mg/kg. Levels of Pb, Cd, and Hg were acceptable by Korean standards. Okadaic acid (OA) and dinophysistoxin-1 (DTX-1) were investigated for monitoring of diarrhetic shellfish poisoning toxins and OA and DTX-1 were not detected. As a result of monitoring of amnesic shellfish poisoning toxins, domoic acid was detected in 5 of 104 samples and detection ratio was 4.8%. The detection period was found as follows; 1 case in January, 1 case in February, 1 case in May, 2 cases in September. These showed that continuous monitoring for the management of shellfish poisoning toxins and heavy metals is required. In addition, this study can be used as reference data to strengthen managing heavy metals in fishery products.

Development and Validation of the Letter-unit based Korean Sentimental Analysis Model Using Convolution Neural Network (회선 신경망을 활용한 자모 단위 한국형 감성 분석 모델 개발 및 검증)

  • Sung, Wonkyung;An, Jaeyoung;Lee, Choong C.
    • The Journal of Society for e-Business Studies
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    • v.25 no.1
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    • pp.13-33
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    • 2020
  • This study proposes a Korean sentimental analysis algorithm that utilizes a letter-unit embedding and convolutional neural networks. Sentimental analysis is a natural language processing technique for subjective data analysis, such as a person's attitude, opinion, and propensity, as shown in the text. Recently, Korean sentimental analysis research has been steadily increased. However, it has failed to use a general-purpose sentimental dictionary and has built-up and used its own sentimental dictionary in each field. The problem with this phenomenon is that it does not conform to the characteristics of Korean. In this study, we have developed a model for analyzing emotions by producing syllable vectors based on the onset, peak, and coda, excluding morphology analysis during the emotional analysis procedure. As a result, we were able to minimize the problem of word learning and the problem of unregistered words, and the accuracy of the model was 88%. The model is less influenced by the unstructured nature of the input data and allows for polarized classification according to the context of the text. We hope that through this developed model will be easier for non-experts who wish to perform Korean sentimental analysis.

Modification of Late Radiation Response of Rat Salivary Glands by Pentoxifylline and Diltiazem (쥐의 타액선 방사선조사 후 만성반응에 Pentoxifylline과 Diltiazem이 미치는 영향)

  • Suh, Hyun-Suk;Yang, Kwang-Mo;Kang, Yun-Kyung
    • Radiation Oncology Journal
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    • v.17 no.3
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    • pp.230-237
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    • 1999
  • Purpose : To elucidate the effects of pentoxifylline and diltiazem on the late response of the salivary glands of the rat after irradiation. Materials and Methods : Sixteen Sprague-Dawley rats were divided into 4 groups : (a) irradiation alone (b) irradiation with pentixifylline (PTX) (c) irradiation with diltiazem (DTZ) (d) irradiation with both PTX and DTZ. Irradiation was given in a single fraction of 16 Gy using 4 MV photon energy through an anterior port encompassing the left side of the salivary gland leaving the right side of salivary gland as a control. PTX, 20 mg/kg and/or DTZ, 50 mg/kg were infused intraperitoneally before irradiation, Two rats from each group were sacrificed on the 10th week and the rest was sacrificed on the 16th week after irradiation. Histopathologic examinations were undertaken for each section and the proportion of vacuolated cells out of the total number of cells under light microscopic fields was calculated. The statistical significance in the difference of the proportion of the vacuolated cells among the experimental groups was evaluated by a $x^2$-test. Results : Irradiated salivary glands of the 10th week group revealed markedly increased number of vacuolated cells compared to those of unirradiated control. The proportion of vacuolated cells was significantly reduced in both the PTX group (p value=0.001) and the combined PTX and DTX group compared to those of irradiation alone group. The DTZ alone group did not reveal the significant reduction of vacuolated cells compared to those of irradiation alone group (p value, >0.05). The 16th week groups revealed similar findings to those of the 10th week group, but the degree of chronic inflammatory cell infiltrates and interstitial fibrosis was increased and the number of acinar cells was reduced compared to those of the 10th week group. Conclusions : PTX significantly reduced the late radiation response of salivary glands, but DTZ did not reduce the same degree as PTX did. Taking the positive results of this study into consideration, it seems reasonable to apply PTX into the clinical trial for the head and neck irradiation to reduce the late radiation sequelae of salivary glands in the near future. At the same time the further experiment to clarify the subcellar mechni는 involved in PTX should be preceded.

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