• Title/Summary/Keyword: DOSE

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Comparison of Doses According to Change of Bladder Volume in Treatment of Prostate Cancer (전립선암 치료 시 방광의 용적 변화에 따른 선량의 비교 평가)

  • Kwon, Kyung-Tae;Min, Jung-Whan
    • Journal of radiological science and technology
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    • v.40 no.3
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    • pp.415-421
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    • 2017
  • In the case of radiation therapy for prostate cancer, a balloon infused with a certain amount of air through the anus is used to reduce rectal dose. Because of the reason, radiation therapy for prostate cancer has acquired CBCT for daily image induction. In order to maintain the anatomical structure most similar to the first CT taken before treatment, it is pretreated, but it can not be said to be perfectly consistent. In two actual treatment regimens, the volume of the bladder was measured as 45.82 cc and 63.43 cc, and the equivalent diameter was 4.4 cm and 4.9 cm. As a result of this study, the mean volume of the bladder was estimated to be 56.2 cc, 105.6 cc by 20 CBCT. The mean dose of CBCT was 1.74% and the mean Bladder mean dose was 96.67%. In case B, PTV mean dose was 4.31%, Bladder mean Dose was estimated to be 97.35%. The changes in the volume of the bladder resulted in changes in the dose of PTV and bladder. The correlation coefficient of bladder dose according to the change of bladder volume showed linearity of mean dose $R^2=-0.94$. The correlation coefficient of the PTV dose according to the volume change of the bladder showed linearity of mean dose $R^2=0.04$. It was found that the dose change of PTV was larger than that of bladder according to the change of bladder volume.

Selection of mAs with Using Table Strap in Computed Tomography Scan (전산화단층촬영 시 환자 고정 밴드를 이용한 선량의 선택)

  • Lee, Young-Hyen;An, Hyeong-Theck
    • Korean Journal of Digital Imaging in Medicine
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    • v.13 no.2
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    • pp.63-69
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    • 2011
  • Table strapis patient fixture for securing the patient movements and falls. if it designed to measure the abdominal circumference and used as an indicator of dose selection at CT scan. it will prevent the overexposure of dose without degradation of image quality and efficiently manage dose of each type of body to technician to deal with CT. First, in order to compare the dose used in CT image and qualitative characteristics. reference image is obtained by examining the abdominal phantom in same conditions with the hospital 120 kVp, 200 mAs, D-Dom (Dynamic Dose Of Modulation). SNR, PSNR, RMSE, MAE, CTDIvol of CT images are compared with reference image. for comparing with reference image, the image that Umbilicus level image of Abdomen CT is stored in the PACS were used. For comparison, the top 12 o'clock portion of the air drawn from the same ROI was measured. CTDIvol, mAs, etc. In order to analyze the characteristics of the image, by measuring the length of the umbilicus circumference, pattern of the dose was analyzed. by using the analyzed perimeter and dose information, To be identified visually, fixed band that scale marked were produced. Use them, If the length of circumference of less than 60 cm 100 mAs, Case of 61~80 cm 120 mAs, Case of 80~100 cm 150 mAs, more than 100 cm 200 mAs, dose selection based on the perimeter, the image was applied. by compare analyzed with the Reference Image, image quality was assessed. by compare with existing tests that equally 200 mAs applied, How much was confirmed that the dose reduction. 1. Depending on the Abdominal circumference, the average PSNR(dB) of the image that differently dose applied was 45.794. 2. Comparing with existing test. the dose of scan that adjusted the mAs depending on the circumference was decreased about 40%. SNR and PSNR of the image that obtained by adjusting the standard mAs based on dose modulation were not much different. Therefore, By choosing a low mAs. dose reduction can be obtained. and the dose selection method that measured Abdominal circumference using a fixed band can protect the overexposure and uniformly apply dose of each type of body to technician to deal with CT.

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A Study on the Dose Constraints for Occupational Exposure: Focusing on Expert Opinions by Field of Ridiation Industry (직무피폭의 선량제약치에 관한 연구: 분야별 전문가 의견 중심으로)

  • Il Park;Chan Hee Park;Kyu Hwan Jung;Chan Ho Park;Yong Geon Kim;Tae Jin Park
    • Journal of Radiation Industry
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    • v.17 no.1
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    • pp.61-67
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    • 2023
  • A Study on the Introduction of Dose Constraints for Occupational Exposures: Focusing on Experts' Opinions by Field of Radiation Industry. The International Commission on Radiological Protection suggests Justification, Optimization, and Dose Limits as the three principles of radiological protection, among which, as a means of protection optimization, ICRP 103 recommends to set dose constraints. In this study, opinions are collected from experts in each category of radiation industries for stakeholder participation to qualify dose constraints. A guidance and questionnaire for analyzing the dose constraints have been developed for their collection, and opinions were collected from radiation protection experts in selected categories. 20 out of 22 experts, consisted with 91%, have assessed the dose constraints setting is necessary, and 2 experts, consisted with 9%, assessed it is unnecessary. The average of dose constraint presented by experts for RI production institutions is to be the highest level of 15.3 mSv, and light-water reactors (14.6 mSv), non-destructive inspection (14.4 mSv), heavy-water reactor and medical institutes (13.9mSv) is to be above the overall average dose constraint. In case of public institutions, the average dose constraint is to be 8.6mSv, and research institutions (8.8mSv), educational institutions (9.6 mSv), waste disposal sites (9.7 mSv), and general industries (10.6 mSv) are resulted to below the overall average dose constraint. As for the means of setting dose constraints, 8 experts out of 22 suggested setting dose constraints for each specific industry or task. And, 5 experts especially suggest setting dose constraints for the specific groups with relatively high exposure, such as workers with above the record levels. As a countermeasure for workers who exceed the dose constraints, 15 experts out of 22 expressed that the cause analyses for them and preparation for a plan of reducing them are necessary.

Toxicity Study of Red Ginseng Acidic Polysaccharide (RGAP) : Single and 2-week Repeated Oral Dose Toxicity Study in Rats

  • Park, Jong-Dae;Song, Yong-Bum;Kwak, Yi-Seong;Kim, Jong-Choon;Im, Doo-Hyun;Junghee Han
    • Toxicological Research
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    • v.19 no.3
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    • pp.173-180
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    • 2003
  • The present study was conducted to investigate the single and 2-week repeated dose toxicity of red ginseng acidic polysaccharide (RGAP) in Sprague-Dawley rats. The test article was administered orally to rats at dose levels of 0, and 2000 mg/kg/day for single dose toxicity study and at dose levels of 0, 250, 500, and 1000 mg/kg/day for repeated dose toxicity study. In both studies, there were no treatment-related effects on mortality, clinical signs, food and water consumption, ophthalmoscopy, urinalysis, hematology, serum biochemistry, necropsy findings and organ weights of all animals treated RGAP. Based on these results, it was concluded that the 2-week repeated oral dose of RGAP may have no toxic effect in rats at a dose level of 1000 mg/kg/day. In the condition of this study, the no-observed-adverse-effect level (NOAEL) was considered to be 1000 mg/kg/day for both sexes.

Using RESRAD-BUILD for Potential Radiation Dose Estimation the Korea Research Reactor-1 When It Opens to the Public as a Memorial Hall

  • Lee, Sangbok;Yoon, Yongsu;Kim, Sungchul
    • International Journal of Contents
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    • v.16 no.2
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    • pp.102-108
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    • 2020
  • The purpose of this study was to estimate and analyze the potential radiation dose that the future visitors and the cleaning staff will be exposed to when the KRR-1 reactor is converted into a memorial hall. The radiation doses were estimated using the RESRAD-BUILD software, where case, building, receptor, shielding, and source parameters were applied as the input data. Also, the basic data for the assessment of the radiation doses were determined in an indirect manner using the data on the waste generated during the decommissioning process of the reactor. The assessment results indicate that the potential radiation dose to the visitors and the cleaning staff will be less than 1 mSv, the annual dose limit for the general public. However, if anyone for a significant period of time is close to the reactor, the overall dose will increase. The radiation dose for the future visitors and the cleaning staff was determined to be lower than the annual dose limit for the general public. Given such a risk, systematic measures, such as periodic monitoring or limiting hours, are imperative.

The Change of Pressure Pain Threshold of Myofascial Trigger Points by Ultrasound Application Method (초음파 적용방식에 따른 근-근막 발통점의 압통각 역치 변화)

  • Lee, Jeong-Woo;Yoon, Se-Won
    • Journal of the Korean Academy of Clinical Electrophysiology
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    • v.1 no.2
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    • pp.61-68
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    • 2003
  • The purpose of this study was to compare the application method of ultrasound on the alteration of pressure pain threshold of myofascial trigger points. We used thirty patients with mayofascial pain syndrome in upper trapezius. Participants classified according to each group in non noxious dose, noxious dose by the ultrasound. The test was measured continuously pre test, post-test by algometer. The following results were obtained; 1. Pressure pain threshold were significantly increased in non-noxious dose and noxious dose group(p<.001). 2. In noxious dose group, pressure pain threshold were more significantly increased than non-noxious dose group(p<.001). These results lead us to the conclusion that non-noxious dose and noxious dose were significantly increased pressure pain threshold of upper trapezius trigger points. Therefore, a further direction of this study will be to provide more evidence that noxious dose have more effect on pressure pain threshold of myofascial trigger points.

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A Study for Optimal Dose Planning in Stereotactic Radiosurgery

  • Suh, Tae-suk
    • Progress in Medical Physics
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    • v.1 no.1
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    • pp.23-29
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    • 1990
  • In order to explane the stereotactic procedure, the three steps of the procedure (target localization, dose planning, and radiation treatment) must be examined separately. The ultimate accuracy of the full procedure is dependent on each of these steps and on the consistancy of the approach The concern in this article was about dose planning, which is a important factor to the success of radiation treatment. The major factor in dose planning is a dosimetry system to evaluate the dose delivered to the target and normal tissues in the patient, while it generates an optimal dose distribution that will satisfy a set of clinical criteria for the patient. A three-dimensional treatment planning program is a prerequisite for treatment plan optimization. It must cover 3-D methods for representing the patient, the dose distributions, and beam settings. The major problems and possible modelings about 3-D factors and optimization technique were discussed to simplify and solve the problems associatied with 3-D optimization, with relative ease and efficiency. These modification can simplify the optimization problem while saving time, and can be used to develop reference dose planning system to prepare standard guideline for the selection of optimum beam parameters, such as the target position, collimator size, arc spacing, the variation in arc length and weight. The method yields good results which can then be simulated and tailored to the individual case. The procedure needed for dose planning in stereotactic radiosurgery is shown in figure 1.

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UV Dose Predictions for Ultra Violet Flowing Water Purification of Axial Reactor Type based on the location of the exit by CFD (CFD에 의한 Axial Reactor Type 자외선 유수살균장치의 출구 위치에 따른 UV Dose 예측)

  • Choi, Jong-Woong;Kim, Seong-Su;Park, No-Suk;Lee, Young-Joo;Chae, Seon-Ha
    • Journal of Korean Society of Water and Wastewater
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    • v.26 no.4
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    • pp.521-533
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    • 2012
  • Interest in application of ultraviolet light technology for primary disinfection that used for the treatment of water for consumption and wastewater has increased significantly in recent years. Analysis of these systems has been carried out using Computational Fluid Dynamics (CFD) procedure. It offers advantages over other techniques in specific circumstances. CFD has emerged as a powerful tool to aid design of a UV reactor by providing the UV dose delivered by the proposed reactor design and allowing engineers to evaluate alternative designs in much less time and at a reasonable cost. In this study, five different configurations of the apparatus depending on the location of the exit are evaluated in terms of maximum dose, minimum dose, flow patterns, particle tracks and transient dose. The configuration 3 results have higher minimum UV dose value and uniform particle distribution of the UV dose on the outlet than other's.

Comparison of Dose Measurement of Glass Dose Meter, Semiconductor Dose Meter, and Area Dose Meter in Diagnostic X-ray Energy (진단영역 X선 에너지에서 유리선량계, 반도체선량계, 면적선량계의 선량 실측 비교)

  • Son, Jin-Hyun
    • Journal of radiological science and technology
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    • v.42 no.6
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    • pp.483-489
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    • 2019
  • This paper obtained and compared these dose values by setting and comparing the X-ray imaging conditions (tube voltage 60 kVp, 70 kVp, 80 kVp, tube current 10 mAs, 16 mAs and X-ray field size are 10 × 10 cm, 15 × 15 cm). Each dose value was measure 10 times and represented as an average value. The purpose of this experiment is to serve as a reference for the X-ray exposure of diagnostic areas according to the type of dosimeter and to help with another dose measurement. The results of the experiment showed very little difference between the glass dosimeter(GD) and semiconductor dosimeter values due to changes in tube voltage of 60, 70, 80 kVp, regardless of field sized, but for dose area product(DAP), the difference in dose value was significant according to field size.

Single and Two-Week Repeated] Oral Dose Toxicity Study of DHP2, a Hydrophobic Drug Delivery Vehicle in Mice

  • Han, Jung-Hee;Chung, He-Sson;Lee, Jong-Hwa;Suh, Jeong-Eun;Lee, Gab-Soo;Kim, Jong-Choon;Kang, Boo-Hyon
    • Toxicological Research
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    • v.20 no.2
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    • pp.123-129
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    • 2004
  • The present study was conducted to investigate the single and 2-week repeated dose toxicity of DHP2, a hydrophobic drug delivery vehicle, in ICR mice. The test article was administered orally to mice at the dose levels of 2.5, 12.5 and 37.5 g/kg for single dose toxicity study and at the dose levels of 0, 2.5, 5, and 10 g/kg for repeated dose toxicity study. In both studies, there were no treatment-related effects on mortality, clinical signs, food and water consumption, ophthalmoscopy, urinalysis, hematology, serum biochemistry, necropsy findings and organ weights of all animals treated DHP2. Based on these results, it was concluded that the 2-week repeated oral dose of DHP2 may have no toxic effect in mice at a dose level of 10 g/kg. In the condition of this study, the no-observed-adverse-effect level (NOAEL) was considered to be 10 g/kg/day for both sexes.