• Journal of the Korean Home Economics Association
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• v.33 no.5
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• pp.129-142
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• 1995

The purpose of his research was to identify the time use of the middle aged apartment-residents in Seoul as a part of collaborative study of family life issues of them. The data were collected from 307 fulltime housewives with at least one child in a middle or high school. Data were analysed by means of the statistics of mean, frequency, Pearson's correlation, ANOVA and Multiple Regression, using a SPSS/PC+ program. The major findings of this research were as follows : Husbands and middle or high school children do much work or study, while housewives do housework about 6 hours a weekday. Much housewives don't manage their time use. Housewives have much leisure time and the in main Leisure activity is TV watching. Much of them don't satisfied with their leisure life. Satisfaction with time use of housewives are related to life satisfaction, and effected by time management and active leisure participation. Most of housewives don't satisfied with their time use.

• Journal of Physiology & Pathology in Korean Medicine
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• v.25 no.5
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• pp.837-842
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• 2011

The purpose of this research was to investigate the effects of 50% ethylalcohol extracts of Lespedeza cuneata G. Don (LE) on the activity of murine immune cells. LE was administered orally once a day for 7 days at the dose of 250 mg/kg. LE increased the cell viability of thymocytes, splenocytes and peritoneal macrophages in vitro and in vivo system, but decreased the cell viability of thymocytes and splenocytes in the presence of concanavalin A in vivo system. Also, the administration of LE was increased the production of ${\gamma}$-interferone, but did not affect the production of interleukin-2 and interleukin-4. Furthermore, LE decreased the phagocytic activity of peritoneal macrophages in vitro and in vivo system, but enhanced the production of nitric oxide. These results suggest that LE has a immuno-regulative action via stimulation of immune cells proliferation.

• Structural Engineering and Mechanics
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• v.59 no.2
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• pp.227-241
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• 2016

A circular plate with constant thickness, finite radius and stiff edge lying on an elastic halfspace is considered. The half-space consists of a soft functionally graded (FGM) layer with arbitrary varying elastic properties and a homogeneous elastic substrate. The plate bends under the action of arbitrary axisymmetric distributed load and response from the elastic half-space. A semi-analytical solution for the problem effective in whole range of geometric (relative layer thickness) and mechanical (elastic properties of coating and substrate, stiffness of the plate) properties is constructed using the bilateral asymptotic method (Aizikovich et al. 2009). Approximated analytical expressions for the contact stresses and deflections of the plate are provided. Numerical results showing the qualitative dependence of the solution from the initial parameters of the problem are obtained with high precision.

• Structural Engineering and Mechanics
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• v.58 no.4
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• pp.613-625
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• 2016

Contact interaction of a beam (flexible element) with an elastic half-plane is considered, when a soft inhomogeneous (functionally graded) interlayer is present between them. The beam is bent under the action of a distributed load applied to the surface and a reaction of the elastic interlayer and the half-space. Solution of the contact problem is obtained for different values of thickness and parameters of inhomogeneity of the layer. The interlayer is assumed to be significantly softer than the underlying half-plane; case of 100 times difference in Young's moduli is considered as an example. The influence of the interlayer thickness and gradient of elastic properties on the distribution of the contact stresses under the beam is studied.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.29 no.2
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• pp.112-122
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• 2016

Objectives : The purpose of this report is to know the effect of Korean medical treatments on pemphigus vulgaris with generalized pruritus. Methods : We treated a 44-years-old woman patient with pemphigus vulgaris on the whole body with Korean medicine. After Korean medical treatment for 17 weeks, we measured the extinction of blisters and decrease of pruritus. We recorded pictures of changes on symptoms. Results & Conclusions : The symptoms of pemphigus vulgaris were significantly improved. The blisters and itching were decreased and skin damages were almost recovered. Thus Korean medical treatments are effective on pemphigus vulgaris.

• Toxicological Research
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• v.9 no.1
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• pp.13-21
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• 1993

The chromosomal aberration of the trichothecene mycotoxins such as T-2 toxin (T-2), HT-2 toxin (HT-2), nivalenol (NIV) and deoxynivalenol (DON) which are one of the most important food borne contaminants produced by Fusarium species fungi, was investigated in the chinese hamster lung cells. These trichothecene mycotoxins showed high cytotoxicity in order of T-2, HT-2, NIV, and DON to the chinese hamster lung cells. Nevertheless high cytotoxicity of these trichothecene mycotoxins, no clastogenicity of T-2 and HT-2 in the range of 0.01-0.0025 ng/ml, of NIV in that of 0.3-0.075ng/ml, and of DON in that of 1.0-0.25 ng/ml was observed in both with and without metabolic activation system.

• Proceedings of the Korea Information Processing Society Conference
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• 2008.11a
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• pp.179-182
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• 2008

본 논문에서는 디지털사진의 효율적인 관리를 위하여 EXIF정보를 이용한 위치 기반의 디지털사진 앨범을 설계하고 구현한다. 촬영된 디지털사진을 과거에 일어난 사건으로 정의하고, 인간이 사건의 인지에 시간적 배경인 시간정보와 공간적 배경인 공간정보를 사용하고 있는 점을 착안하여 이를 기반으로 한 앨범의 설계와 제작을 보인다. 시스템은 대표적인 디지털사진 파일의 포맷으로 사용되는 JPEG/EXIF 포맷의 EXIF정보에 포함된 사진촬영 날짜와 GPS정보를 이용하여 설계되어 기존의 사진 관리시스템보다 효율적인 사용자 상호작용이 가능하다.

• 우유
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• s.39 winter
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• pp.30-34
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• 1989

• 우유
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• s.38 fall
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• pp.37-38
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• 1989

• Asian-Australasian Journal of Animal Sciences
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• v.31 no.4
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• pp.595-606
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• 2018

Objective: The Fusarium mycotoxins of deoxynivalenol (DON) and zerolenone (ZEN) cause health hazards for both humans and farm animals. Therefore, the main intention of this study was to reveal DON and ZEN effects on the mRNA expression of pro-inflammatory cytokines and other immune related genes in the liver of piglets. Methods: In the present study, 15 six-week-old piglets were randomly assigned to the following three different dietary treatments for 4 weeks: control diet, diet containing 8 mg DON/kg feed, and diet containing 0.8 mg ZEN/kg feed. After 4 weeks, liver samples were collected and sequenced using RNA-Seq to investigate the effects of the mycotoxins on genes and gene networks associated with the immune systems of the piglets. Results: Our analysis identified a total of 249 differentially expressed genes (DEGs), which included 99 upregulated and 150 downregulated genes in both the DON and ZEN dietary treatment groups. After biological pathway analysis, the DEGs were determined to be significantly enriched in gene ontology terms associated with many biological pathways, including immune response and cellular and metabolic processes. Consistent with inflammatory stimulation due to the mycotoxin-contaminated diet, the following Kyoto encyclopedia of genes and genomes pathways, which were related to disease and immune responses, were found to be enriched in the DEGs: allograft rejection pathway, cell adhesion molecules, graft-versus-host disease, autoimmune thyroid disease (AITD), type I diabetes mellitus, human T-cell leukemia lymphoma virus infection, and viral carcinogenesis. Genome-wide expression analysis revealed that DON and ZEN treatments downregulated the expression of the majority of the DEGs that were associated with inflammatory cytokines (interleukin 10 receptor, beta, chemokine [C-X-C motif] ligand 9), proliferation (insulin-like growth factor 1, major facilitator superfamily domain containing 2A, insulin-like growth factor binding protein 2, lipase G, and salt inducible kinase 1), and other immune response networks (paired immunoglobulin-like type 2 receptor beta, Src-like-adaptor-1 [SLA1], SLA3, SLA5, SLA7, claudin 4, nicotinamide N-methyltransferase, thyrotropin-releasing hormone degrading enzyme, ubiquitin D, histone $H_2B$ type 1, and serum amyloid A). Conclusion: In summary, our results demonstrated that high concentrations DON and ZEN disrupt immune-related processes in the liver.