• 한국임상수의학회지
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• 제34권6호
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• pp.445-448
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• 2017

A 1.5-year-old neutered male domestic short hair cat was presented with multiple nodular mass, and suspected mast cell tumor on the surface of the right ear, accompanied by submandibular lymph node involvement. Histopathological Examinations and KIT (CD117) immunohistochemical staining was performed after the surgical resection of the entire right ear pinna. This patient was diagnosed with an anaplastic mast cell tumor with a diffuse positive cytoplasmic expression of KIT. Imatinib mesylate was prescribed after surgical resection; the patient presented without recurrence or metastasis for 2 years. Mild leukopenia was observed as the only side effect of imatinib mesylate during medication.

• 한국임상수의학회지
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• 제34권6호
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• pp.437-440
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• 2017

A five-month-old, male Domestic Korean shorthair was referred to our hospital with a history of lethargy, anorexia, and globoid cardiac silhouette on thoracic radiography. Physical examination showed dehydration and anemia was revealed on blood analysis. On thoracic radiography and echocardiography, the patient showed pericardial effusion and ultrasound-guided pericardiocentesis was performed. A Rivalta test of the pericardial effusion showed a positive result. As the patient had recurrent pericardial effusion, pericardiectomy was performed. He was tentatively diagnosed with wet form feline infectious peritonitis (FIP) and treated with Polyprenyl immunostimulant (PI). Neurological signs were eventually seen and he was euthanized. Histopathologic changes with markedly expanded neutrophils, lymphocytes, plasma cells, and macrophages with fibrous connective tissue and collagenous fibers were detected. Immunohistochemistry for FIP antigen was performed and results showed FIPV-positive multifocal aggregates of cells. Pericardial effusion is an atypical condition in cats with FIP, but can be presented. This case report describes FIP with pericardial effusion in a cat, in which definitive diagnosis of FIP was done using biopsy via pericardiectomy.

• 한국동물위생학회지
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• 제41권2호
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• pp.119-123
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• 2018

There has recently been a growing demand for pathodiagnosis to determine the cause of death in cats. We retrospectively analyzed the diseases diagnosed in cats that were submitted to Animal and Plant Quarantine Agency (APQA) in 2015~2017. Overall diagnostic rate in feline samples was 85.2% (n=104/122). Among diagnosed cases, infectious diseases (n=63) were responsible for most of the feline diseases and feline panleukopenia (n=29) were most prevalent. Highly pathogenic avian influenza (HPAI) H5N6 was first diagnosed in cats at the end of December 2016 in the HPAI outbreaks. One case in 2015, 4 cases in 2016, and 14 cases in 2017 were associated with animal abuse, such as trauma and poisoning. These results suggest that suitable vaccination of feline infectious diseases, monitoring of the susceptible domestic animals during HPAI outbreaks, and interest on veterinary forensics to prevent and determine animal abuse are needed.

• 한국임상수의학회지
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• 제25권1호
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• pp.19-22
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• 2008

Adenomyosis is a nonneoplastic proliforation of uterine glands characterized by multicentric infiltration of endometrial tissues into the myometrium. A female domestic short hair cat with unknown age was referred to local animal hospital in Busan for ovariohysterectomy to prevent the unwanted offspring. At the time of surgery, the uterus was enlarged with multiple nodular protrusion on the serosa. On the cut surface of uterus, elevation of the endometrium and hypertrophied myometrium were observed. Microscopically, the uterus was characterized by severe proliforation of endometrial glands into the lumen and within the myometrium. The intra-myometrial endometrium is circumferentially surrounded by bundles of hypertrophic smooth muscle cells. These endometrial glands had tall columnar epithelium lacking nuclear atypia and mitoses. In our best knowledge, this is the first report of feline adenomyosis in Korea.

• 한국동물위생학회지
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• 제40권2호
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• pp.143-147
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• 2017

A Korean domestic short hair (1-year-old, male) presented with 2 to 3 weeks of seizures, aggressive behavior, vomiting, anorexia, and lethargy. The frequency of seizure had gradually increased from once a week to once every 3 hours. Physical and neurologic examination, diagnostic screening tests, including complete blood count (CBC), serum chemistry, electrolyte, coagulation test, X-ray, ultrasonography, and urinalysis were performed. Feline Leukemia Virus (FeLV), Feline Immunodeficiency Virus (FIV) and Toxoplasma spp. All tested negative, but the Feline Corona Virus (FCoV) kit revealed a positive result. To determine the exact diagnosis, magnetic resonance imaging (MRI) was performed but yielded no specific findings. The patient was then diagnosed with idiopathic epilepsy and treatment of phenobarbital was initiated. A month's treatment with phenobarbital proved ineffective as symptoms worsened. Zonisamide was then selected as an additional anticonvulsant. After adding zonisamide, symptoms improved, and seizures abated for 15 months. This is the first case report in South Korea describing the use of phenobarbital and zonisamide in the treatment of a cat with idiopathic epilepsy.

• 한국임상수의학회지
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• 제37권4호
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• pp.223-226
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• 2020

Cytauxzoonosis is caused by Cytauxzoon felis (C. felis) in wild and domestic cats. However, cytauxzoonosis is uncommon in Asia. Additionally, clinical reports of C. felis infection along with associated complications are rare. A seven-year-old neutered male Maine Coon cat was presented with acute dyspnea and lethargy despite the absence of a history of overseas travel. Mild regenerative anemia and autoagglutination were detected in hematological investigations. The parasitic and viral PCR assays revealed infection with C. felis and feline immunodeficiency virus (FIV). Thoracic radiographs showed pleural effusion with secondary bacterial infection. Ultimately, a diagnosis of infection-induced secondary immune-mediated hemolytic anemia (IMHA) and pyothorax was established. The cat was treated with a combination of atovaquone, prednisolone, and cyclosporine over 6 months and the final treatment was completed 8 months after initiation of therapy. This is the first report of its kind demonstrating successful management of feline IMHA and fatal pyothorax induced by FIV and C. felis in South Korea.

• 한국임상수의학회지
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• 제23권3호
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• pp.361-365
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• 2006

A spayed female, 5-year-old, weighing 2.7 kg, domestic short hair cat was referred to Veterinary Medical Teaching Hospital, Seoul National University. The clinical signs of this patient were weight loss, sneezing, respiratory distress, nasal discharge, epistaxis, ocular discharge, left exophthalmos, and left facial edema and deformity. The laboratory tests represented mild leukocytosis. On the skull radiographs, soft tissue density filled nasal cavity with loss of turbinate detail was found. Destructive and lytic changes of the left nasal bone with soft tissue swelling were identified. On the thorax radiographs, there were a tracheobronchial lymph node swelling and a soft tissue round mass in the left caudal lung field. On computed tomographic scan images, asymmetrical destruction of turbinate and nasal septum and increased soft tissue opacity in the nasal cavity were identified. Destruction of the lateral maxillary bone, invasion to the left retrobulbar region, and craniodorsal deviation of the left eye were seen. Also, there was lysis of hard palate and cribriform plate. Invasion to the brain was found. The patient was diagnosed as nasal lymphoma by cytology and histopathology.

• 한국임상수의학회지
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• 제31권2호
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• pp.108-111
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• 2014

7세 중성화된 암컷 고양이가 3개월 동안 지속된 간헐적인 구토 증상으로 진료 의뢰되었다. 혈액 검사와 진단영상학적 검사에서 비정상적인 소견은 관찰되지 않았다. 내시경 검사에서 위 동체 점막에 국소적인 미란이 관찰되었고, 해당 병변들에 대한 조직병리학적 검사를 통해 림프구성 위염으로 진단하였다. 프레드니솔론 투약 7일 후에 구토 및 식욕 부진 증상은 소실되었지만, 장기간 투약에 의한 부작용 발생 때문에 프레드니솔론 대신에 싸이클로스포린을 처방하였다. 환자의 상태는 개선되었고, 구토와 식욕부진은 더 이상 관찰되지 않았다. 본보는 만성 구토를 보이는 고양이 림프구성 위염에 있어 싸이클로스포린은 치료 약물로 적용 가능함을 시사한다.

• 한국임상수의학회지
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• 제34권5호
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• pp.388-391
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• 2017

A 8-month-old, spayed female, Domestic shorthair cat lived in a shelter was presented with pelvic limbs ataxia and dysuria. Serum biochemical profile abnormalities were hyperproteinemia and decreased albumin/globulin (A:G) ratio (0.70). Results of cerebrospinal fluid (CSF) analysis were mixed cells pleocytosis with predominance neutrophils and an increase in protein concentration. In addition, feline coronavirus was detected by realtime RT-PCR in CSF. Magnetic resonance imaging (MRI) findings revealed lesions of the lumbar spinal cord. Based on clinical signs, MR finding, CSF analysis and realtime RT-PCR result in CSF, this case was diagnosed as feline infectious peritonitis (FIP) associated meningomyelitis. Although prednisolone and mycophenolate mofetil were administrated, clinical signs were not resolved and progressed to tetraplegia and coma status. This case presentation describes that feline infectious peritonitis virus could affect the lumbar spinal cord only and cause meningomyelitis with pelvic limbs ataxia without other neurological signs.

• Parasites, Hosts and Diseases
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• 제48권2호
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• pp.145-149
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• 2010

Medically important arthropods, including fleas, play an important role in causing clinical disorders and disease in man and domestic animals. This study was conducted to determine the seasonal flea infestations for domestic dogs from different geographic regions of Iran. A total of 407 fleas, belonging to 5 different species, were recovered from 83 domestic dogs from 3 regions. There was a distinctive pattern of species distribution and infestations with the highest infestation rates observed in a temperate climate and higher rainfall. Additionally, fleas were observed over all seasons, except February and March, with the highest infestation rate observed in August (24.7%) and the lowest rate in January (1.7%). They also parasitize dogs with a different spectrum of species. The cat flea, Ctenocephalides felis (67.5%), exhibited the highest prevalence among all flea species found on dogs. Thus, climatic conditions and seasonal patterns impact on flea infestation and must be considered in developing control programs.