• 제목/요약/키워드: DNI

검색결과 24건 처리시간 0.022초

신생아 균혈증에서 Delta Neutrophil Index의 진단적 의의 (Diagnostic Significance of the Delta Neutrophil Index and Other Conventional Parameters in Neonatal Bacteremia)

  • 고일두;전인수;김황민
    • Pediatric Infection and Vaccine
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    • 제24권1호
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    • pp.1-6
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    • 2017
  • 목적: 본 연구에서는 delta neutrophil index (DNI)가 신생아 균혈증을 예측하는 지표로서의 효용성을 다른 지표들과의 비교를 통해 알아보고자 하였다. 방법: 원주세브란스 기독병원 신생아 중환자실에 발열을 주소로 입원한 환아들과 입원 중 발열이 있었던 생후 31일 미만 환아 146명을 대상으로 혈액배양검사와 동시에 시행한 총 백혈구 수, 절대호중구수, DNI, 혈소판 수, C-반응단백(C-reactive protein, CRP)에 대하여 분석하였다. 결과: 균혈증이 있었던 환아 77명의 평균 재태주수는 38.74주, 출생 체중은 3.20 kg였다. 대조군의 평균 재태주수는 33.34주, 출생 체중은 2.20 kg였다. 균혈증의 원인은 Staphylococcus aureus (22명), Staphylococcus epidermidis (18명), Streptococcus agalactiae (8명) 등이었다. DNI와 CRP만이 재태주수와 출생 체중 보정 후 균혈증과 연관성을 보여 area under the ROC curve를 조사하였고 DNI 0.70, CRP 0.68이었다. 결론: DNI는 신생아 균혈증을 예측하는 데 효과적인 지표이다. 다른 인자들과 함께 고려한다면 균혈증을 예측하는 데 더 도움이 될 것이다.

Delta neutrophil index as a predictor of vesicoureteral reflux in children with febrile urinary tract infection

  • Kim, Jae Eun;Oh, Jun Suk;Yoon, Jung Min;Ko, Kyung Ok;Cheon, Eun Jung
    • Childhood Kidney Diseases
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    • 제26권1호
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    • pp.46-51
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    • 2022
  • Purpose: Delta neutrophil index (DNI) indicates immature granulocytes in peripheral blood and has been confirmed to be effective as a prognostic factor for neonatal sepsis. Also, it has been reported to have diagnostic value in acute pyelonephritis and in predicting vesicoureteral reflux (VUR) in the infant. We conducted the study to verify whether DNI is also helpful in the entire pediatric age group with febrile urinary tract infection (UTI). Methods: Medical records of children hospitalized for febrile UTIs were analyzed retrospectively. All subjects underwent kidney ultrasound and voiding cystourethrography. In the group with and without VUR, we compared sex and age, and the following laboratory values: the white blood cell count, neutrophil, polymorphonuclear leucocyte, eosinophil, hemoglobin, platelet count, C-reactive protein, DNI value, and the finding of ultrasound. Results: A total of 315 patients (163 males and 152 females; range, 0-127 months) were eligible, and 41 patients (13%) had VUR. As a result of univariate analysis, the white blood cell count, neutrophil, DNI, and ultrasonic abnormalities were high in the reflux group, and the hemoglobin and lymphocyte fraction values were low. The value of DNI and the abnormal ultrasound were significantly higher in the reflux group on the multivariate analysis. The area under the curve value of the receiver operating curve was higher in DNI (0.640; 95% confidence interval, 0.536-0.744; P=0.004), and the DNI cutoff value for VUR prediction was 1.85%. Conclusions: We identified that ultrasound findings and DNI values were helpful predictors of VUR in pediatric febrile UTIs.

TRNSYS를 이용한 대규모 태양열발전시스템 성능 연구 (Study on the Large Scale Solar Thermal Power Plant System by Using the TRNSYS Program)

  • 김종규;강용혁;김진수;이상남;유창균;윤환기
    • 한국신재생에너지학회:학술대회논문집
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    • 한국신재생에너지학회 2006년도 추계학술대회
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    • pp.176-179
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    • 2006
  • This paper describes the procedure of the basic design and transient variation of performance for a 1MWe large scale solar thermal power plant system (STPPS) by using the commercial software tool of TRNSYS. In order to simulate the transient variation of STPPS's performance, the basic design of STPPS are preceded by using the THERMOFLEX, Three different days of DNI weather data of Daejeon in 2005 are used to calculate the performance. For a high DNI data values, the general ing power of 1.1 MWe and flow rate of 1.4kg/s at $804W/m^2$ are good agreement with the basic design value of 1.0 MWe, 1.36 kg/s at $800 /m^2$. Using the other weather data of low and sudden decreasing DNI values, the results show that the output power and flow rate follow well the DNI variation. Based on the results, it is allowed to use the Program to estimate the performance of STPPS for variety of DNI data.

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화상환자에서 패혈증의 조기 예측인자로서의 DNI (Delta Neutrophil Index as an Early Marker of Sepsis in Burn Patients)

  • 김총명;하철민
    • 대한화상학회지
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    • 제22권2호
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    • pp.38-44
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    • 2019
  • Purpose: The immature granulocyte count has been reported to be a marker of infection and sepsis. The difference in leukocyte subfractions (delta neutrophil index, DNI) in ADVIA 2120 reflects the fraction of circulating immature granulocytes in the blood. This study evaluated the clinical utility of DNI as a severity and prediction marker in critically ill patients with burn sepsis. Methods: One hundred and sixty nine patients admitted to the burn care unit were studied. DNI (the difference in leukocyte subfractions identified by myeloperoxidase and nuclear lobularity channels) was determined using a specific blood cell analyzer. Results: Seventy one patients (42 %) were diagnosed with burn sepsis. DNI was significantly higher in patients with burn sepsis than in patients without (P<0.01). Delta neutrophil index was a better indicator of burn sepsis than C-reactive protein, lactate, white blood cell count, HCO3, base excess, lactate, procalcitonin (odds ratio, 6.31; confidence interval 2.36~16.90; P<0.01). And the receiver operating characteristic curves showed that delta neutrophil index, AUC 0.795 (95% confidence interval, 0.721~0.869; P<0.05) was a better predictor of burn sepsis than lactate, procalcitonin, white blood cell, base excess and abbreviated burn severity index. Conclusion: Delta neutrophil index may be used as a early marker of patients with burn sepsis.

Deep Neck Infection Caused by Infected Dentigerous Cyst: A Case Report

  • Kim, Gyeong-Mi;Oh, Ji-Su;You, Jae-Seek;Moon, Seong-Yong;Choi, Hae-In
    • Journal of Oral Medicine and Pain
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    • 제46권4호
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    • pp.150-154
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    • 2021
  • Deep neck infection (DNI) is a potentially serious pathology that can lead to serious complications and high rate of mortality. Since DNI affects the cervical spaces, which can compromise airway, aggressive antibiotic administration and prompt surgical drainage are essential for recovery. Although most causes of DNI are known to be dental infections, developmental cysts such as dentigerous cysts are relatively few causes. In this case, we report a rare patient with severe deep neck space infection caused by infected third molar with dentigerous cyst.

Effect of Delayed Inoculation After Wounding on the Development of Anthracnose Disease Caused by Colletotrichum acutatum on Chili Pepper Fruit

  • Kim, Sang-Gyu;Kim, Yn-Hee;Kim, Heung-Tae;Kim, Young-Ho
    • The Plant Pathology Journal
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    • 제24권4호
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    • pp.392-399
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    • 2008
  • Detached chili pepper fruits were inoculated with the conidial suspension of Colletotrichum acutatum JC-24 simultaneously (simultaneous inoculation, SI) and at delayed time (delayed inoculation, DI) after wounding with (delayed wound inoculation, DWI) or without additional wounding (delayed non-wound inoculation, DNI) at the inoculation time. Disease severity was significantly lowered by DNI, compared to SI. By DNI, the disease reduction rates were proportional with the length of delayed time, and greater at the high temperature range (18, 23 and $28^{\circ}$) than at the low temperature ($13^{\circ}$) tested. DWI was also effective in reducing the disease severity especially at 18oC; however, its effectiveness was lower than for DNI. In light microscopy, parenchyma cells at the wounding sites were modified structurally, initially forming new cell walls crossing cytoplasm, enlarged with multiple periclinal cell divisions, and finally layered like wound periderms. In DWI, the above structural modifications occurred, showing the restriction of the fungal invasion by the cell walls in enlarged modified cells, while no definite cellular modifications were found with proliferation of fungal hyphae in SI. Sclerenchyma-like cells with thickened cell walls were proliferated around the wounding sites, which were partially dissolved by DWI, probably leading to some disease development. All of these results suggest that the decline of the anthracnose disease in pepper fruit by the delayed inoculations may be derived from the structural modifications related to the healing processes of the previous wound inflicted on the tissues.

10 kW급 접시형 태양열발전시스템 사업모델 개발 및 운전특성 분석 (Development of 10 kW Dish-Stirling System for Commercialization and Analysis of Operating Characteristics)

  • 김종규;이상남;강용혁
    • 한국태양에너지학회 논문집
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    • 제30권6호
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    • pp.118-124
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    • 2010
  • In order to develop commercial model of 10kW dish-Stirling solar thermal power system, modification for the exiting facility was taken for a year as a Leading Project in KIER. During the project, solar tracking system, control and monitoring system and high durability reflector were developed and long term operation were performed. The solar tracking system was tested for four months to investigate the degree of precision and adapted to the control system for an actual operation from October in 2009. The sun tracking accuracy of ${\pm}4$ mrad using modified control system was obtained and the system operated successfully during the experimental period. The monitoring system displays engine pressure, electric generation amounts, generator RPM, receiver temperatures, and etc. from Stirling engine and weather data of Direct Normal Irradiation, Horizontal Global Insolation, wind speed & direction, and atmosphere temperature from weather station. According to the operating results in a clear sky day, electric power of 6,890 W was generated at the DNI value of 850 W/$m^2$ and the averaged solar-to-electricity efficiency during a whole day reached to 18.99%. From the overall operating results, linear power generation trend could be observed with increasing DNI value. The solar-to-electricity efficiency achieved to 19% around the DNI value of 700 W/$m^2$ and increased to 20% when the DNI value goes up to 900 W/$m^2$.

Clinical Features of Deep Neck Infections and Predisposing Factors for Mediastinal Extension

  • Kang, Shin-Kwang;Lee, Seok-Kee;Oh, Hyun-Kong;Kang, Min-Woong;Na, Myung-Hoon;Yu, Jae-Hyeon;Koo, Bon-Seok;Lim, Seung-Pyung
    • Journal of Chest Surgery
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    • 제45권3호
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    • pp.171-176
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    • 2012
  • Background: Deep neck infections (DNI) can originate from infection in the potential spaces and fascial planes of the neck. DNI can be managed without surgery, but there are cases that need surgical treatment, especially in the case of mediastinal involvement. The aim of this study is to identify clinical features of DNI and analyze the predisposing factors for mediastinal extension. Materials and Methods: We reviewed medical records of 56 patients suffering from DNI who underwent cervical drainage only (CD group) and those who underwent cervical drainage combined with mediastinal drainage for descending necrotizing mediastinitis (MD group) from August 2003 to May 2009 and compared the clinical features of each group and the predisposing factors for mediastinal extension. Results: Forty-four out of the 56 patients underwent cervical drainage only (79%) and 12 patients needed both cervical and mediastinal drainage (21%). There were no differences between the two groups in gender (p=0.28), but the MD group was older than the CD group (CD group, $44.2{\pm}23.2$ years; MD group, $55.6{\pm}12.1$ years; p=0.03). The MD group had a higher rate of co-morbidity than the CD group (p=0.04). The CD group involved more than two spaces in 14 cases (32%) and retropharyngeal involvement in 12 cases (27%). The MD group involved more than two spaces in 11 cases (92%) and retropharyngeal involvement in 12 cases (100%). Organism identification took place in 28 cases (64%) of the CD group and 3 cases of (25%) the MD group (p=0.02). The mean hospital stay of the CD group was $21.5{\pm}15.9$ days and that of the MD group was $41.4{\pm}29.4$ days (p=0.04). Conclusion: The predisposing factors of mediastinal extension in DNI were older age, involvement of two or more spaces, especially including the retropharyngeal space, and more comorbidities. The MD group had a longer hospital stay, higher mortality, and more failure to identify causative organisms of causative organisms than the CD group.

일사량 직산분리 모델에 따른 표준기상연도 데이터와 태양광 발전 예측량의 불확실성 (Variation of Solar Photovoltaic Power Estimation due to Solar Irradiance Decomposition Models)

  • 조을효;이현진
    • 한국태양에너지학회 논문집
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    • 제39권3호
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    • pp.81-89
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    • 2019
  • Long-term solar irradiance data are required for reliable performance evaluation and feasibility analysis of solar photovoltaic systems. However, measurement data of the global horizontal irradiance (GHI) are only available for major cities in Korea. Neither the direct normal irradiance (DNI) nor the diffuse horizontal irradiance (DHI) are available, which are also needed to calculate the irradiance on the tilted surface of PV array. It is a simple approach to take advantage of the decomposition model that extracts DNI and DHI from GHI. In this study, we investigate variations of solar PV power estimation due to the choice of decomposition model. The GHI data from Korea Meteorological Administration (KMA) were used and different sets of typical meteorological year (TMY) data using some well-known decomposition models were generated. Then, power outputs with the different TMY data were calculated, and a variation of 3.7% was estimated due to the choice of decomposition model.

대규모 태양열발전 기본설계 및 동특성 계산 (Basic Design and Dynamic Simulation of Large Scale Solar Thermal Power Plant)

  • 김종규;강용혁;김진수;윤환기;유창균;이상남
    • 한국태양에너지학회 논문집
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    • 제27권1호
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    • pp.55-61
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    • 2007
  • This paper describes the procedure and calculation results of basic design and transient variation of performance of 1 MWe large scale solar thermal power plant (STPP) by using the commercial software of THERMOFLEX and TRNSYS, respectively. In order to simulate the transient variation of STPP, the results of basic design are necessary. The design standard of the STPP is 1 MWe generation with solar only at high DNI condition and then 0.6 MWe output power for 1 hour using stored energy when the DNI becomes lower unable to operate normally. The results of basic design show the important design data of flow rates, water/steam conditions at each equipments and the estimated efficiency of STPP. In addition, dynamic simulation results of STPP are predicted and plotted for one year and three different days weather data of Daejeon.