• Title/Summary/Keyword: DLS

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A Study on the Activation of School Library Consulting: Based on the Schools not Employing a Teacher Librarian (학교도서관 컨설팅의 활성화 방안에 관한 연구 - 사서교사 미 배치 학교를 중심으로 -)

  • Song, Gi-Ho
    • Journal of Korean Library and Information Science Society
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    • v.40 no.2
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    • pp.335-353
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    • 2009
  • The purpose of this study is to suggest practical plans to improve the school library consulting, especially in case of a teacher librarian is not assigned. As a result of analyses, consulting through methods of the School Library Assistant Group lacks spontaneity, expertise, council, and independence. Besides, each office of education operates it as a marketing. A main goal of school consulting is to foster independent problem- solving of individual schools. Accordingly, it is necessary to build an union management system, develop a standard staff manual, construct DLS based on-line consulting, and design educational training programs of consultants for its successful consulting.

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[ $W_{1}/O/W_{2}$ ] Multi-emulsion Capsules Containing Ascrobic Acid-2-Glucoside Prepared Using PCL-based Amphiphilic Di- and Tri-block Copolymers

  • Cho, Heui-Kyoung;Chang, Woo-Hyuck;Cheong, In-Woo
    • Proceedings of the Polymer Society of Korea Conference
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    • 2006.10a
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    • pp.262-262
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    • 2006
  • Biodegradable and amphiphilic di-block and tri-block copolymers, prepared with monomethoxy poly ethylene glycol (MPEG) and ${\varepsilon}-caprolactone\;({\varepsilon}-CL)$, were used for the application of W1/O/W2 multi- emulsion capsules. The effects of topology and the ratio of hydrophilic moiety of PCL-based polymers on the encapsulation efficiency of the $W_{1}/O/W_{2}$ multi-emulsion capsules containing Ascorbic Acid-2-Glucoside (AA-2-G) were investigated. The ratio of PEG and PCL was 1:0.5, 1:0.75, 1:1, and 1:1.25. PEG-PCL block copolymers were added to the first step of the preparation of $W_{1}/O$ emulsions. The dispersion stability, the particle size, the morphology of the $W_{1}/O/W_{2}$ multi-emulsion capsules were observed using an on-line turbidity meter, dynamic light scattering (DLS), a confocal microscopy (with FITC) and an optical microscopy. Biodegradable behavior of the PEG-PCL block copolymers and release behavior of AA-2-G were also observed by Gel Permeation Chromatography (GPC) and High Performance Liquid Chromatography (HPLC).

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Poly(vinyl pyrrolidone) Conjugated Lipid System for the Hydrophobic Drug Delivery

  • Lee, Hye-Yun;Yu, Seol-A;Jeong, Kwan-Ho;Kim, Young-Jin
    • Macromolecular Research
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    • v.15 no.6
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    • pp.547-552
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    • 2007
  • Water soluble polymer, poly(vinyl pyrrolidone) was chosen to conjugate with 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-(succinyl) (N-succinyl DPPE) to make a new drug delivery system. PVP with an amine group (amino-PVP) was polymerized by free radical polymerization. The amine group of amino-PVP was conjugated with the carboxylic group of N-succinyl DPPE. The resultant conjugate could form nanoparticles in the aqueous solution; these nanoparticles were termed a lipid-polymer system. The critical aggregation concentration was measured with pyrene to give a value of $1{\times}10^{-3}g/L$. The particle size of the lipid-polymer system, as measured by DLS, AFM and TEM, was about 70 nm. Lipophilic component in the inner part of the lipid-polymer system could derive the physical interaction with hydrophobic drugs. Griseofulvin was used as a model drug in this study. The loading efficiency and release profile of the drug were measured by HPLC. The loading efficiency was about 54%. The release behavior was sustained for a prolonged time of 12 days. The proposed lipid-polymer system with biodegradable and biocompatible properties has promising potential as a passive-targeting drug delivery carrier because of its small particle size.

Study on the Pixel Design for the Prerrue-stable Fringe-field Switching (FFS) Mode with 3 Slit Structure (압력에 안정한 3분할 FFS 모드의 화소 설계에 관한 연구)

  • Kim, Mi-Sook;Seen, Seung-Min;Jung, Yeon-Hak;Kim, Hayng-Yuil;Kim, Seo-Yoon;Lim, Young-Jin;Lee, Seung-Hee
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.18 no.7
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    • pp.647-651
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    • 2005
  • We studied the external pressure-stable advanced frnge field switching (FFS) pixel design with 3 slit sructue. In this mode, a patterned pixel slit is partitioned into 3 areas, namely, two edges and a center, where the edge slit angle is larger than the center slit angle. Thus the reverse twist region in the pixel edge is reduced comparing to the conventional FFS mode so that the LC dynamics in this region becomes very stable. And also, when the external pressure is applied to the panel at the high voltage, the disclination lines (DLs) were barely intruded into active area. Therefore, the structure is use for the pen based system such as the tablet personal computer (PC), personal digital asistant (PDA).

Analysis and Design of Branch Line Coupler using Microstrip Lines with Overlay (덮개층이 있는 마이크로스트립 선로를 이용한 브랜치 선로 결합기 해석 및 설계)

  • 이승엽
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.12 no.5
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    • pp.795-801
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    • 2001
  • A method of miniaturizing branch line coupler is presented. The method utilizes the microstrip line with overlay(or superstrate). The frequency dependent characteristics, dispersion and characteristic impedance, of this line are obtained by Immitance method in spectral domain and Method of Line. The relevant spectral domain Green's function is given and used to obtain numerical results. The branch line couplers with overlays are designed and fabricated at 2 GHz. The experimental results show that the size of coupler with overlay(${epsilon}_r$=10.2) is 31.4 precent smaller than conventional coupler. This minimized coupler is suitable for Butler Matrix as feeder for mobile communication beam forming antenna.

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Surface Modification of Magnetites Using Maltotrionic Acid and Folic Acid for Molecular Imaging

  • Selim, K.M.Kamruzzaman;Lee, Joo-Hee;Kim, Sun-Jung;Xing, Zhicai;Kang, Inn-Kyu;Chang, Yong-Min;Guo, Haiqing
    • Macromolecular Research
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    • v.14 no.6
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    • pp.646-653
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    • 2006
  • Highly hydrophilic, uniform, superparamagnetic and nontoxic maltotrionic acid (MA)-coated magnetite nano-particles (MAM) were prepared and characterized by TEM, DLS, XRD and VSM. MA was used to improve the biocompatibility, monodispersity and non-specific intracellular uptake of nanoparticles. Folic acid (FA) was subsequently conjugated to the MAM to preferentially target KB cells (cancer cells) that have folate receptors expressed on their surfaces and to facilitate nanoparticles in their transit across the cell membrane. Finally, fluorescence isothiocyanate (FITC) was added to the nanoparticles to visualize the nanoparticle internalization into KB cells. After the cells were cultured in a media containing the MAM and MAM-folate conjugate (FAMAM), the results of fluorescence and confocal microscopy showed that both types of nanoparticles were internalized into the cells. Nevertheless, the amount of FAMAM uptake was higher than that of MAM. This result indicated that nanoparticles modified with MA and FA could be used to facilitate the nanoparticle uptake to specific KB cells (cancer cells) for molecular imaging.

Transport behavior of PVP (polyvinylpyrrolidone) - AgNPs in saturated packed column: Effect of ionic strength and HA (포화 컬럼실험에서 이온강도 변화 및 유기물질 출현에 의한 PVP로 코팅된 은나노 입자의 거동 연구)

  • Heo, Jiyong;Han, Jonghun;Her, Namguk
    • Journal of Korean Society of Water and Wastewater
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    • v.30 no.3
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    • pp.263-270
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    • 2016
  • Recent Engineered nanoparticles were increasingly exposed to environmental system with the wide application and production of nanomaterials, concerns are increasing about their environmental risk to soil and groundwater system. In order to assess the transport behavior of silver nanoparticles (AgNPs), a saturated packed column experiments were examined. Inductively coupled plasma-mass spectrometry and a DLS detector was used for concentration and size measurement of AgNPs. The column experiment results showed that solution chemistry had a considerable temporal deposition of AgNPs on the porous media of solid glass beads. In column experiment, comparable mobility improvement of AgNPs were observed by changing solution chemistry conditions from salts (in both NaCl and $CaCl_2$ solutions) to DI conditions, but in much lower ionic strength (IS) with $CaCl_2$. Additionally, the fitted parameters with two-site kinetic attachment model form the experimental breakthrough curves (BTCs) were associated that the retention rates of the AgNPs aggregates were enhanced with increasing IS under both NaCl and $CaCl_2$ solutions.

Policy for planned placement of sensor nodes in large scale wireless sensor network

  • Sharma, Vikrant;Patel, R.B;Bhadauria, HS;Prasad, D
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.10 no.7
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    • pp.3213-3230
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    • 2016
  • Sensor node (SN) is a crucial part in any remote monitoring system. It is a device designed to monitor the particular changes taking place in its environs. Wireless sensor network (WSN) is a system formed by the set of wirelessly connected SNs placed at different geographical locations within a target region. Precise placement of SNs is appreciated, as it affects the efficiency and effectiveness of any WSN. The manual placement of SNs is only feasible for small scale regions. The task of SN placement becomes tedious, when the size of a target region is extremely large and manually unreachable. In this research article, an automated mechanism for fast and precise deployment of SNs in a large scale target region has been proposed. It uses an assembly of rotating cannons to launch the SNs from a moving carrier helicopter. The entire system is synchronized such that the launched SNs accurately land on the pre-computed desired locations (DLs). Simulation results show that the proposed model offers a simple, time efficient and effective technique to place SNs in a large scale target region.

Synthesis and pH-Dependent Micellization of Sulfonamide-Modified Diblock Copolymer

  • Pal Ravindra R.;Kim Min Sang;Lee Doo Sung
    • Macromolecular Research
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    • v.13 no.6
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    • pp.467-476
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    • 2005
  • The main objective of this study was to develop and characterize pH-sensitive biodegradable polymeric materials. For pH-sensitivity, we employed three kinds of moieties: 2-amino-3-(lH-imidazol-4-yl)-propionic acid (H), N-[4-( 4,6-dimethyl-pyrimidin-2ylsulfamoyl)-phenyl]succinamic acid (SM), and 2- {3-[ 4-( 4,6-dimethyl-pyrim­idin- 2-ylsulfamoyl)-phenylcarbamoyl]-propionylamino} -3-(3 H - imidazol-4-yl)-propionic acid (SH). The pH -sensitive diblock copolymers were synthesized by ring opening polymerization and coupling reaction from poly(ethylene glycol) (MPEG), $\varepsilon$-caprolactone (CL), D,L-lactide (LA) and pH-sensitive moieties. The pH-sensitive SH molecule was synthesized in a two-step reaction. The first step involved the synthesis of SHM, a methyl ester derivative of SH, by coupling reaction of SM and L-histidine methyl ester dihydrochloride, whereas the second step involved the hydrolysis of the same. The synthesized SM, SHM and SH molecules were characterized by FTIR, $^{1}H$-NMR and $^{13}C$-NMR spectroscopy, whereas diblock copolymers and pH-sensitive diblock copolymer were characterized by $^{1}H$-NMR and GPC analysis. The critical micelle concentrations were determined at various pH conditions by fluorescence technique using pyrene as a probe. The micellization and demicellization studies of pH-sensitive diblock copolymers were also done at different pH conditions. The pH-sensitivity was further established by acid-based titration and DLS analysis.

Preparation and Characterization of Nanoparticles Using Poly(N-isopropylacrylamide)-$Poly({\varepsilon}-caprolactone)$ and Poly(ethylene glycol)-$Poly({\varepsilon}-caprolactone)$ Block Copolymers with Thermosensitive Function

  • Choi, Chang-Yong;Jang, Mi-Kyeong;Nah, Jae-Woon
    • Macromolecular Research
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    • v.15 no.7
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    • pp.623-632
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    • 2007
  • Thermosensitive nanoparticles were prepared via the self-assembly of two different $poly({\varepsilon}-caprolactone)$-based block copolymers of poly(N-isopropylacrylamide)-b-$poly({\varepsilon}-caprolactone)$ (PNPCL) and poly(ethylene glycol)-b-$poly({\varepsilon}-caprolactone)$ (PEGCL). The self-aggregation and thermosensitive behaviors of the mixed nanoparticles were investigated using $^1H-NMR$, turbidimetry, differential scanning microcalorimetry (micro-DSC), dynamic light scattering (DLS), and fluorescence spectroscopy. The copolymer mixtures (mixed nanoparticles, M1-M5, with different PNPCL content) formed nano-sized self-aggregates in an aqueous environment via the intra- and/or intermolecular association of hydrophobic PCL chains. The microscopic investigation of the mixed nanoparticles showed that the critical aggregation concentration (cac), the partition equilibrium constants $(K_v)$ of pyrene, and the aggregation number of PCL chains per one hydrophobic microdomain varied in accordance with the compositions of the mixed nanoparticles. Furthermore, the PNPCL harboring mixed nanoparticles evidenced phase transition behavior, originated by coil to the globule transition of PNiPAAm block upon heating, thereby resulting in the turbidity change, endothermic heat exchange, and particle size reduction upon heating. The drug release tests showed that the formation of the thermosensitive hydrogel layer enhanced the sustained drug release patterns by functioning as an additional diffusion barrier.